Insecticidal toxicities of carvacrol and thymol derived from Thymus vulgaris Lin. against Pochazia shantungensis Chou & Lu.

Jun?Hwan Park,Na-Hyun Lee,Sang-Guei Lee,Hoi-Seon Lee 한국농약과학회 2017 한국농약과학회 학술발표대회 논문집 Vol.2017 No.4

ImmunoDot법에 의한 전신성 류마티스 질환의 자가항체 검사

박성환,김선준,김성일,민준기,이상헌,홍연식,조철수,김호연 최신의학사 1997 最新醫學 Vol.40 No.7

써키트트레이닝 부하강도에 따른 고등학교 유도선수들의 체력향상 효과

박순진,김준환 龍仁大學校 武道硏究所 2003 武道硏究所誌 Vol.14 No.1

The research which it sees bitterly the circuit training this against the physical strength improvement effect of the high school induction bow to examine and it was for. 20 person Kyonggi-Do subject matter K high school induction staffs in 10 person two group A group and 10 person B group it shared in the object and beriberi of the different load burglar the kit Tray ning it executed bitterly. Week 3 month, possibility, Friday, A group to execute load burglar 50% B group per the each item to execute with load burglar 80% the disturbance hour did 30 middle age. Bitterly the circuit training the item which is necessary to the induction bow selected 12 items. The Tray of 8 weeks circuit training with after words it came down a same conclusion after executing. There is a difference which first, the Tray ning 8 weeks considers statistically from after B group the Tray ning war results comparison hour B group A group more is a possibility of knowing the fact that the muscular power improves a lot. There is a difference which first, the training 8 weeks considers statistically from after B group the training war results comparison hour B group A group more is a possibility of knowing the fact that the muscular power improves a lot. The secondth, training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more is a possibility of knowing the fact that the pure foot power improves. The thirdth, training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more pliability some is a possibility of knowing the fact that it improves. The fourthth, training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more agile characteristic improves a lot is a possibility of knowing the fact that. Fifth, the training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more the core abolition old calendar some is a possibility of knowing the fact that it improves. Sixth, the training 8 weeks there is a difference which considers statistically from after B group and the training war results comparison hour B group A group more muscle endurance some is a possibility of knowing the fact that it improves. When it tries to the result of over, the circuit training from of 8 weeks training under high school judo player improves the physical strength of the induction bow and it gives the help which even from in the that is many in muscular power improvement the possibility of knowing the thing it was.

이중관에서의 응축열전달 최적화에 관한 연구

박일환,박준석 한국기술교육대학교 2003 論文集 Vol.10 No.1

The present study has been conducted entropy analysis on a saturated R134a vapour flowing through and condensed outside or inside horizontal cooling tube. The flow condensation heat transfer performance is dominated by the phase change process with low mass flux, and by two phase flow condensation with high mass flux. And there exists an optimum mass flux and a tube diameter ratio that results in minimum of entropy generation.

血栓症과 打撲性 充血 및 高脂血症에 順氣導痰湯 및 化瘀湯이 미치는 影響

박원환,최달영,文濬典 東國大學校韓醫學硏究所 1993 東國韓醫學硏究所論文集 Vol.2 No.1

To see both Shunqidaotantang(dissipate phlegm and promote vital energy circulation) and Huayutang(blood circulation and disperse blood stasis) influencing on thrombosis, contusion-hyperemia, and hyperlipidemia, at first we measured the density of FDP, the quantity of fibrino-gen, prothrombin time, and the number of platelet of rat taken thrombosis by endotoxin. Secondly we measured the increase-rate of "paw swelling", the number of platelet, the quantity of fibrino-gen, and pothrombin time of rat taken contusion-hypermia. And then we measured the quantity of total cholesterol in serum and of H.D.L-cholesterol and of triglyceride and of phospholipid and of β-lipoprotein, its weight, and the variation of the quantity of electrolyte of rat taken hyperlipidemia by the oral-injection of cholesterol. As a result, we can conclude as follows: 1. Out of the test of thrombosis, we can recognize not only the noticeable increae of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and the density FDP in case of Shunqid?otant?ng-injected rat and Huay?t?ng-injected rat. 2. Out of the test of contusion-hypermia, we can recognize not only the noticeable increase of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and "increase-rate of paw swelling" in case of Shunqid?otant?ng-injected rat and Huay?t?ng-injected rat. 3. Out of the test of hyperlipidemia, at first we can recognize that test rat's weight increased as close as that of normal rat. And we can recognize the noticeable decrease of the triglyceride and phospholipid and β-lipoprotein. " Also, in case of the variation of electrolyte we can recognize the decrease of calcium and potassium in Shunqidaotantang-injected rat, and of sodium and magnesium in Huayutang-injected rat. Thus, as the above-mentioned, in covering thrombosis, contusion-hypermia, and hyperlipidemia, the effect of Shunqiduotantang and Huay?t?ng can be recognized. Granting that Huayutang reveals its effectiveness in thrombosis and contusion-hyperemia, and Shunqid?otant?ng in hyperlipidemia, it can be inferred that contusion-hyperemia is like "model of blood stasis form" as thrombosis and hyperlipidemia "phlegm-retention diseases form ", and both phlegm-retention and blood stasis have correlation each other.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

고량강의 항염증 작용에 대한 연구

박히준,이제현,김수영,심범상,구헌종,강전모,최일환,이재동,김남재,이지숙,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objective : The use of herbal therapy is becoming an increasingly attractive approach for the treatment of various inflammatory disorders. The Alpiniae officinari Rhizoma is popular in Aisa as a traditional herbal medicine. Alpiniae officinari Rhizoma is a species of the ginger family(Zingiberacease). Method : This study was performed to investigate the anti-inflammatory effect of Alpiniae officinari Rhizoma extract by the methods of "carrageenan induced paw edema" and "Lipopolysaccharide-induced inflammatory mediators in mouse macrophage RAW 264.7 cells". Result : We suggest that Alpiniae officinari Rhizoma extract decreased paw volume induced by plantar injection of carrageenan. Also Alpiniae officinari Rhizoma extract inhibited nitric oxide, prostaglandin E₂production and induced nitric oxide synthase, cyclooxygenase-2 protein expression in Mouse macrophage RAW 264.7 cells stimulated with lipopolysaccharide. Conclusion : This study shows that Alpiniae officinari Rhizoma extract seems to have anti-inflammatory effect by inhibition of nitric oxide, prostaglandin E_(2) production and nitric oxide synthase, cyclooxygenase-2 protein expression.

血栓症과 打撲性 充血 및 高脂血症에 順氣導痰湯 및 化瘀湯 미치는 影響

朴元煥,崔達永,文濬典 동국대학교 한의학연구소 1993 東國韓醫學硏究所論文集 Vol.2 No.1

To see both Shunqidaotantang(dissipate phlegm and promote vital energy circulation) and Huayutang(blood circulation and disperse blood stasis) influencing on thrombosis, contusion-hyperemia, and hyperlipidemia, at first we measured the density of FDP, the quantity of fibrinogen, prothrombin time, and the number of platelet of rat taken thrombosis by endotoxin. Secondly we measured the increase-rate of "paw swelling", the number of platelet, the quantity of fibrinogen, and prothrombin time of rat taken contusion-hyperemia. And then we measured the quantity of total cholesterol in serum and of H.D.L-cholesterol and of triglyceride and of phospholipid arid of P-lipoprotein, its weight, and the variation of the quantity of electrolyte of rat taken hyperlipidemia by the oral-injection of choleserol. As a result, we can conclude as follows : 1. Out of the test of thrombosis, we can recognize not only the noticeable increae of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrornbin tirne and the density of FDP in case of Shunqidaotantang-injected rat and Huayutang-injected rat. 2. Out of the test of contusion-hyperemia, we can recognize not only the noticeable increase of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and "increase-rate of paw swelling" in case of Shunqidaotantang-injected rat and Huayutang-injected rat. 3. Out of the test of hyperlipidemia, at first we can recognize that test rat s weight increased as close as that of normal rat. And we can recognize the noticeable decrease of the triglyceride and phospholipid and P-lipoprotein. Also, in case of the variation of electrolyte we can recognize the decrease of calcium and potassium in Shunqidaotantang-injected rat, and of sodium and magnesium in Huayutang-injected rat. Thus, as the above-mentioned, in covering thrombosis, contusion-hypermia, and hyperlipidemia, the effect of Shunqidaotantang and Huayutang can be recognized. Granting that Huayutang reveals its effectiveness in thrombosis and contusion-hyperemia, and Shunqidaotantang in hyperlipidemia, it can be inferred that contusion-hyperemia is like model of blood stasis form as thrombosis and hyperlipidemia "phlegm-retention diseases form", and both phlegm-retention and blood stasis have correlation each other.

촉각센서를 위한 실리콘 마이크로다이어프램 배열의 제조

박기열,심준환,류인식,조찬섭,이종현 경북대학교 센서기술연구소 1994 센서技術學術大會論文集 Vol.5 No.1

Silicon diaphragm arrays were fabricated by silicon micromachining using porous silicon. Fabricated diaphragms consist of 3x3 array. The thickness of diaphragm is 5μm and theire size are 200x200, 300X300 and 400X400μm^(2), respectively. Several % of resistance change is observed, when stress was applied at diffused resistor on the diaphragm. Microdiaphragm arrays were easily fabricated by silicon micromachining using porous silicon, and we confirmed feasibilty of application at tactile sensor.

계지의 항염 효과에 관한 연구

박히준,이지숙,이재동,김남재,표지희,강전모,최일환,김수영,심범상,이제헌,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : Cinnamomi Ramulus (CR), the young twing of Cinnamomi loureirii nees, has been used for treating symptoms related to pain. rheumatic arthritis and inflammation in Korean herb medicine. This study was carried out to investigate the anti-inflammatory effect of CR in vivo and in vitro. Methods : Extracts of CR were prepared and the chemical components of the extracts were examined by gas chromatography-mass spectrometry (GC-MS). The extracts were administrated to the rat paw edema model induced by carrageenan to evaluate the anti-inflammatory effect of CR. The expressions of nitric oxide (NO). prostaglandin E2(PGE2), inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 were also quantified in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages to survey the effect of CR in vitro. The main components were cinnamaldechyde and coumarin. Results : We examined the anti-inflammatory activity of the 80% ethanol extract of Cinnamomi Ramulus in vivo by using carrageenan-induced rat paw edema model. Maximum inhibition of 54.9% was noted at the dose of 1000㎎/㎏ after 2 hours of drug administration in carrageenan-induced rat paw edema and this showed a potent anti-inflammatory effect. Conclusions : The results showed that Cinnamomi Ramulus suppressed dose-dependently LPS-induced NO production in RAW 264.7 macrophages and also decreased iNOS protein expression. Cinnamomi Ramulus also showed a significant inhibitory effect in LPS-induced PGE2 production and COX-2 expression.