바이오 디젤유로서 미강유의 분무개선에 관한 연구

주은선,정석용 慶尙大學校生産技術硏究所 1994 生産技術硏究所論文集 Vol.10 No.-

This paper is focused on the propriety examination and application plan as a substiution fuel in the rece-bran oil which is obtained as by-product when the rice is milled. Compared with the light-oil, the rice-bran oil has high viscosity, and causes erosion of nozzle, clogging phenomenon. So, in order to solve these problems, the ultrasonic oscillator device has been used and the design of horn was performed, on the basis of physical experimental data of the rice-bran oil. The purpose of the paper is to construct the optimal fuel-injection system using rice-bran oil, therefore it has been performed the experiment to improve the characteristics of an atomization by adding ultrasonic energy on spraying fuel. The sauter mean diameter(SMD) and distribution of spary was measured by using the magnesium oxide method and the immersion one.

원발성 유방암에서 Sodium Iodide Symporter의 발현과 ^(99m)Tc-MIBI 유방스캔의 관계

석주원,김성장,곽희숙,이창훈,김인주,김용기,배영태,김동수 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.6

목적: hNIS는 갑상선 조직 외에 다른 조직들에서도 발현된다고 알려져 있다. 유방암 세포는 그런 조직들 중에 하나이며, 그에 의한 유방암의 방사성옥소치료의 가능성이 제시되고 있다. 본 연구에서는 유방암 조직에서 hNIS의 발현정도를 알아보고, ^99mTc-MIBI 유방스캔과 hNIS의 발현 정도와의 관계를 조사하여 보았다. 대상 및 방법: 본 연구에서는 유방암으로 수술을 시행했던 56명의 환자를 대상으로 하였다. hNIS의 발현은 면역조직화학염색에 의해서 평가되었으며, 그 결과를 ^99mTc-MIBI 유방스캔의 판정 결과와 비교하였다. 결과: 전체 56명의 환자에서 hNIS의 발현율은 41.1%였다. 병리학적 진단에 의해 침윤성관상피암종이었던 49명에서의 발현율은 42.9%, 관상피내암종이었던 7명에서의 발현율은 28.6%였다. ^99mTc-MIBI 유방스캔에서 국소섭취 소견이 관찰되었던 41명에서의 hNIS의 발현율은 31.7%였다. 비정상적인 섭취 소견이 관찰되지 않았던 15명의 환자에서의 hNIS의 발현율이 의미있게 높게 관찰되었다(66.7%, p>0.05). 결론: 유방암 환자에서의 hNIS의 발현율은 그다지 높지 않았다. ^99mTc-MIBI 유방스캔에서 섭취증가 소견이 없을 때 hNIS의 발현율이 더 높았다. Purpose: Human Na^+/I- symporter (hNIS) is known to be expressed in many tissues other than thyroid gland. The breast cancer cells are one of them and the possibility of radioiodine therapy in treatment of the breast cancer may be suggested. We investigated the expression rate of hNIS and the relationship between the expression of hNIS and the finding of 99mTc-MIBI scintimammography in the breast cancer. Materials and Methods: Surgically proved 56 patients with breast cancer were the subjects of this study. The expression of hNIS were evaluated by immunohistochemistry and the results were compared to the findings of 99mTc-MIBI scintimammography. Results: Overall expression rate of hNIS was 41.1% in 56 patients. According to the pathologic diagnosis, it was 42.9% in 49 patients with invasive ductal carcinoma and 28.6% in the 7 patients with ductal carcinoma in situ. The expression rate of hNIS in the 41 cases with a focal increased uptake at he breast lesion on 99mTc-MIBI scintimammogram was 31.7%. That in the 15 cases without any abnormal uptake on the scan was significantly higher(66.7%, p<0.05). Conclusion: The expression rate of hNIS in the patients with breast cancer was not so high. The rate was higher in the patients with no increased uptake at the breast lesion on 99mTc-MIBI scintimammography. (Korean J Nucl Med 2002;36;325-32)

순천향대학교 천안병원에 입원한 로타바이러스 감염 위장관염 환자의 임상양상

최석주,전세윤,김승수,박경배,김용배,박준수 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

..

직장에 발생한 원발성 악성 흑색종 1예

이석주,김광일,김동호,김홍성,우상민,최덕례,정현용 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

An extremely rare case of primary melanoma involving only rectum is reported. This 59 year-old male patient was admitted to the hospital because of hematochezia, difficulty of defection. Endoscopic examination and radical excision showed polypoid lesion with ulceration which measured 6x6x3cm in 2cm from the anal verge. Histopathologic, H&E stain and electron microscopic examination(EM) were performed from endoscopic biopsies and excisional mass. We are reporting a case primary rectal melanoma with brief review of literature.

암모니아 및 아질산성 질소 산화세균의 분리 및 특성

이용석,유주순,정수열,박춘수,최용락 한국농화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.1

본 연구는 폐수 중의 질소 제거를 위한 생물학적 처리용 미생물 개발을 위한 목적으로 질소의 산화 능력이 뛰어난 균주를 분리하였다. 분리된 세균 중에서 질소 산화능과 생육 속도가 뛰어난 CH-N 균주를 선별하였으며, 생리, 생화학적인 특성 조사에 의해 Bacillus sp로 추정되어 Bacillus sp. CH-N이라 명명하였다. 분리 균주는 0.5% glucose가 포함된 초기 pH가 7.0인 암모니아 및 아질산성 질소 함유 배지에서 30시간 배양 후 가가 85%와 90%의 암모니아성과 아질산성 질소가 단시간에 질소의 감소율을 나타내었다. 폐수 및 생활하수에 분리 균주를 이용한 결과, 수질 속의 암모니아성 질소가 단시간에 크게 감소시키는 효과를 확인하였다. 균주를 고정시킨 담체의 질소산화 효과를 시험하고자 Bacillus sp. CH-N을 고정시킨 세라믹 담체를 이용한 결과, 배양 2일 후에는 암모니아성 질소가 전부 제거되었다. In order to improve the system for biological nitrogen oxidizing process in sewage and wastewater, a bacterium having high abilities to oxidize of nitrogen was isolated from wastewater and polluted soils. The strain was identified to Bacillus sp. CH-N, based on the physiological and biochemical properties. Characteristics and oxidizing ability of both ammonia and nitrite were examined for the strain, Bacillus sp. CH-N. The strain showed the oxidizing rate about 80% to 90% on the sewage and wastewater after 48 h culture. The nitrogen oxidizing rate was increased in proportion to the initial concentration of glucose. The microorganism, Bacillus sp. CH-N cell immobilized on ceramic carrier were evaluated for the oxidation of ammonia in culture media.

피로시험에 의한 다단변후재의 응력확대계수 해석

최용식,장세인,박종주,석창성 成均館大學校 科學技術硏究所 1991 論文集 Vol.42 No.1

Variable thickness plates have been used as structural members in practical engineering services. The stress intensity factor values near and at the thickness interface of the plate must be determined for use of integrity evaluation and designing of such structures. Several studies of the stress intensity factor on the variable thickness plates have been reported by the theoretical and the finite element analysis. Besides, there exists no clear solution for that. In this study, another experimental analysis method of the stress intensity factor on the variable thickness plate using fatigue test technique was introduced. And the stress intensity factor on the plate was determined by the method using SS41 carbon steel plate.

Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

Prevotella nigrescens의 용혈특성에 관한 연구

곽주석,장훈상,장석우,이수종,유용욱,민경산 大韓齒科保存學會 2005 Restorative Dentistry & Endodontics Vol.30 No.4

세균의 용혈활성은 세균이 숙주 내에서 생존하기 위해 필요한 철을 획득하기위한 특성이며 기능면에서 볼 때 숙주에 대한 중요한 독력인자로 간주될 수 있다. 본 연구에서는 괴사치수 및 치근단 치주염으로 진단된 환자의 근관에서 분리한 Prevotella nigrescens의 용혈활성을 다양한 조건 하에서 측정하여 그 특성을 규명하는 것을 목적으로 한다. 1. 임상에서 분리한 P. nigrescers와 표준균주인 P. nigrescers ATCC 33563에서 모두 용혈활성이 나타났다. 2. 사람, 면양 및 말 세 가지 종에 대해 용혈활성을 비교한 결과 사람의 적혈구에서 가장 강한 용혈활성을 나타내었다. 3. 용혈소 억제제인 NaN₃와 dithiothreitol (DTT)는 농도의존적으로 P.nigrescers의 용혈활성을 감소시켰다 (p<0.05). 4. P. nigrescers가 최대 용혈활성을 나타내는 최적의 pH는 4이었으며, 50℃이하의 온도에서는 용혈활성을 보였으나 95℃에서 급격히 감소하였다. 5.배양조건에 따른 P. nigrescens의 용혈활성을비교한 결과 10% CO₂배양기에 배양한 경우혐기성 조건에서 배양한 것보다 더 높은 용혈활성을 보였다. Hemolytic property is a specific feature of bacteria to obtain iron which is essential for its survival in host tissues. Therefore, it is thought to be one of several factors of virulence. The purpose of this study was to investigate the hemolytic properties of Prevotella nigrescens isolated from the teeth diagnosed as pulp necrosis and apical periodontitis under the presence of hemolysin inhibitors such as NaN3 and dithiothreitol, heat, various pH and cultural conditions. The results were as follows; 1. Clinically isolated P. nigrescens strains and standard P. nigrscens ATCC 33563 showed hemolytic activity. 2. P. nigrescens showed higher hemolytic activity against human erythrocytes than sheep or horse erythrocytes. 3. NaN₃ and dithiothreitol (DTT) reduced the hemolytic activity of P. nigrescens in a dose dependent manner (p<0.05). 4. Optimal pH for the maximum hemolytic activity of P. nigrescens was 4.0 and the hemolysin was stable under the 50℃, but the hemolytic activity was significantly decreased at 95℃. 5. P. nigrescens cultured in 10% CO₂ condition showed higher hemolytic activity than the bacteria cultured in the anaerobic condition.[J Kor Acad Cons Dent 30(4):335-343,2005]

수중식물과 침전물에 의한 용존산소 변화량 결정 : 하천모델 이용법;a Stream Model Approach

이용석,최은주,박민대,박석순 江原大學校 附設 環境硏究所 1993 環境硏究 Vol.10 No.-

하천모델을 이용하여 한강 지류인 탄천에서 수초와 침전물에 의한 용존산소 변화량을 측정하였다. 수질자료에 따르면 탄천은 상류의 부영양화 지역 (Eutrophic Zone)과 하류의 강부수성 지역 (Polysaprobic Zone)으로 구분되며 상류는 수초의 광합성과 호흡이, 하류는 침전물 산소요구량이 수중 용존산소 농도 결정에 주 역할을 하고 있다. 하천조사는 1990년5월과 10월 2회에 걸쳐 2일간 연속적으로 실시되었다. 조사 결과 상류의 경우 수초 광합성과 호흡에 의한 매우 큰 용존산소 일주변화가 관찰되었다. 그러나 하류의 경우 침전물 산소요구량이 크고 수초 성장이 없기 때문에 일주변화가 거의 나타나지 않는 매우 낮은 농도가 측정되었다. 1차 조사시 상류에서 수중식물의 광합성량과 호흡양은 각각 55~100g 0₂/m²/day, 30~70g 0₂/m²/day으로 측정되었으며, 2차 조사시 각각 40~80g 0₂/m²/day, 25~55g 0₂/m²/day으로 측정되었다. 하류에서는 침전물 산소요구량이 1차 및 2차 조사시 동일하게 4~100g 0₂/m²/day로 측정되었다. The dissolved oxygen changes caused by aquatic plants and sediments were comput-ed in the Tancheon, a tributary of the HanRiver, by utilizing a stream model. According to the collected water quality conditions, the Tancheon was classified into two distinc-tive zones which were eutrophic zone in upstream area and polysaprobic zone in downstream area. The dissolved oxygen levels of the stream were determined mainly by the photosynthesis and respiration of the macrophytes in upstream area and by the sediment oxygen demand in downstream. Field data were obtained from two synoptic stream surveys performed during May and October, 1990 for two consecutive days The high diurnal dissolved oxygen variation was observed in upstream area due to an excessive growth of aquatic plants. In downstream area, however, little diurnal varia-tion with low dissolved oxygen level was observed, which would be attributed to high sediment oxygen demand and no discernible aquatic plant growth. In upstream area, the dissolved oxygen changes caused by the photosynthesis and respiration were ranged from 55g 100g 0₂/m²/day from 30 to 70 g 0₂/m²/day, respectively, during the first survey. The changes were ranged from 40 to 80g 0₂/m²/day for the photosynthesis and from 25 to 55g 0₂/m²/day for the respiration during the second survey, In downstream area, the sediment oxygen demands were measured from 4 to 100g o₂/m²/day during both surveys.

유동해석을 사용한 공조기 입구형상의 최적설계

최영석,이용갑,주종일 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 논문에서는 전산유체해석 기법을 이용하여 저소음 · 고효율 공조기의 입구형상에 대한 유동해석을 하였다.공조기 입구형상을 결정하는 여러 설계변수가 입구와 출구의 유동조건과 유로의 압력손실에 미치는 영향을 평가하였다.이를 바탕으로 입구와 출구유동의 균일성과 압력손실의 최소화를 만족하는 최적의 설계변수를 결정하여 공조기의 최적설계를 달성하였다.