급성 백혈병 관해유도요법후 발생한 다발성 비장농양 1예

이홍기,김선운,박경동,이현성,주영돈,손창학 인제대학교 2000 仁濟醫學 Vol.21 No.1

Splenic abscess is a rare illness. Its incidence has ranged from 0.14 to 0.7 % in various autopsies conducted in the US. Even in the most recently published articles, diagnosis was made only in autopsies in 37 % of the cases. While splenic abscess may arise occasionally from contiguous spread of infection or direct trauma to the spleen, usually it develops with hematogenous spread or infection. But, bacterial endocarditis is the most common cause. RUQ pain of abdomen developed in only half of series. Splenomegaly, fever and leucocytosis was also present. When splenic abscesses are being considered in a differential diagnosis, CT scan of the abdomen has been the most sensitive diagnostic tool. Streptococcal species are the most common bacterial isolates from splenic abscesses, S. aureus is the next most common. Salmonella species are seen commonly in patients with sickle cell hemoglobinopathy. Because of the high mortality related for splenic abscess, the treatment of choice is splenectomy with adjunctive antibiotics. However, percutaneous drainage has been successful alternative. We reported a 19-years old female patient who had splenic abscess after remission induction chemotherapy of acute leukemia, successfully treated with splenectomy.

소아 만성 부비동염에서 단순촬영상과 OMU CT상의 비교

이병돈,박상호,김장묵,이승균,장혁순,강주원,김장욱 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Most commonly and widely used diagnostic tool for chronic paranasal sinusitis in children is plain X-ray check not only because of small radiation dose and easy performance, but because of low cost. However ostiomeatal unit computed tomography(OMU CT) was known to be more accurate and recommended recently by many physicians. The author have studied for both OMU CT and plain X-ray of paranasal sinuses and compaird their findings in 90 chidren(180 sides of sinus) aged from 4 to 14 years who suspected having sinusitis. OMU CT was taken after plain X-ray examination (Caldwell's view, water's view, lateral view), and the time interval betweeen these two examination was O to 14 days (average 4.7 days). The following results were obtained. Considering that OMU CT was accurate, the rate of correspondence in diagnosis of sinus pathology between plain X-ray and OMU CT was 48.3% in the ethmoid sinus, 51.1% in the maxillary sinus, 41.9% in the sphenoid sinus, 43.4% in the frontal sinus. If all OMU CT findings had been accurate, the incidence of false positives according to plain X-ray was 25.5% in the ethmoid sinus, 28.3% in the maxillary sinus, 70.8% in the spenoid sinus and 77.8% in the frontal sinus. While, the incidence of false negatives according to plain X-ray was 85.9% in the ethmoid sinus, 70.5% in the maxillary sinus, 50.0% in sphenoid sinus and 37.5% in the frontal sinus. A routine preoperative OMU CT is recommended, which allows a detailed evaluation of pathologic changes and anatomical relations of the paranasal sinuses before surgical interventiaon for the paranasal sinuses. Considering the above facts, diagnosis of pediatric sinusitis only by plain X-ray was inadequate and OMU CT was necessary.

몇 소나무類의 葉綠素 含量의 月別 變化

李慶學,金甲泰,朱洸영,曺炅眞,李敦求 서울大學校 農科大學 1985 서울대농학연구지 Vol.10 No.2

植物體는 生存 또는 生長을 위해 光合成作用을 하며, 綠色植物은 이를 위한 色素로서 葉綠體를 가지고 있다. 따라서 이의 含量은 生長能力이나 各種 stress에 대한 生理的 活成變化를 나타내는 指標로 이용되는데 이에 對한 硏究報告는 基礎的 資料로서의 重要性에도 불구하고 林木 특히 소나무類에 있어서는 극히 드물었다. 이에 서울大學交 農科大學 構內에 있는 소나무類 5樹種에 對한 針葉單位生重量當 葉綠素含量을 月別測定한 結果 樹種間의 含量差異는 뚜렷하니지 않았으나 測定時期間에는 差異를 보였다. 總葉綠素의 含量變化는 葉綠素 a의 含量變化에 起因하며 이는 여름철에는 높고 겨울철에는 낮았다. 또한 最大値는 2年生 針葉을 7, 8月에 測定했을 때 나타났다. 이러한 結果를 綜合해 볼 때 소나무類의 生理的 生活은 葉綠素 a와 密接한 關係를 갖고 있는 것으로 思料된다. To obtain the fundamental data about the chlorophyll contents of some conifers, monthly measurements of them per unit fresh weight(g) of needles were performed. The results were summarized as follows. 1. Difference of total chlorophyll contents between measuring times in a species was clear but not between species. Total chlorophyll content in summer showed high value and that in winter did low value. 2. In general, the total chlorophyll contents of the conifers showed the highest values in two-year-old needles, measured in July or August. 3. Monthly change of total chlorophyll contents was mainly due to that of the contents of chlorophyll a, and the contents of chlorophyll b was not varied greatly with measuring times. 4. It seems that the physiological activity of needles was closely related with the contents of chlorophyll a.

단계중합법에 의한 Core-Shell 구조의 Acrylic Composite Particle 제조에 관한 연구

이선룡,윤주섭,강돈오,설수덕 동아대학교 생산기술연구소 2001 生産技術硏究所硏究論文集 Vol.6 No.2

Core-shell composite latex has the both properties of core and shell components. This unique behavior of core-shell composite latex can be used in many industrial fields. However, in preparation of core-shell composite latex, several unexpected are observed, such as, particle coagulation, low degree of polymerization, and formation of new particles during shell polymerization. To solve the disadvantages, we study the effect of initiator concentrations, surfactant concentrations, and reaction temperature on the core-shell structure of Polymethyl methacrylate/polystyrene and polystyren/polymethyl methacrylate. Particle size and particle size distribution were measured by using Particle Size Analyzer, and the morphology of the core-shell composite latex was determined by using Transmission Electron Microscope. Glass temperature was also measured by using Differential Scanning Calorimeter. To identify the core-shell structure, pH of the two composite latex solutions were measured.

황해 동남 해역의 수괴지표성 요각류 및 모악류의 분포와 수괴특성

박주석,이삼석,강영실,이병돈,허성회 동의대학교 기초과학연구소 1993 基礎科學硏究論文集 Vol.3 No.1

Distribution of indicator species of copepods and chaetognaths were studied as an indicator species of water mass in the southeastern area of the Yellow Sea. Undinula darwini, Lucicutia flavicornis, Pleuromamma gracilis, Euchaeta resselli, Euchaeta plana and Sagitta enflata were found to be reliable indicator species for determining warm water mass. Of these species, E. plana and E. russelli have a weak tolerance on the low temperature. Sagitta crassa was indicator species of neritic waters: Sagitta bedoti was that of mixing waters. Centropages agdominalis represented neritic cold waters. In February U. darwini, L. flavicornis, P. gracilis, E. russelli, E. plana and S. enflata occurred in the western waters of Cheju-Do where warm waters over 14℃ occupied. Centropages abdominalis occurred in the northern area beyond Chindo with water temperature less than 10℃. E. plana, E. russelli and S. bedoti were found at the regions between Cheju-Do and Chindo where the water temperature was 12∼14℃ corresponding to the mixing waters. Based on cluster analysis and T-S diagram in February three different water masses were identified from the south to the north. In August, water masses were analyzed at two different layers, 0∼20m and 20m∼bottom layers, separated by thermocline depth. In 0∼20m layer, E plana and E. russelli were found from the western waters of Cheju-Do to Daehuksando. In 20m∼bottom layer, E. russelli and E. plana occurred at the northwestern waters of Cheju-Do with the water temperature warmer than 12℃. C. abdominalis was found at the northern area beyond Chindo. Based on the cluster analysis and T-S diagram in August three different water masses at 0∼20m and 20m∼bottom layers were identified from the coast to the offshore. C. abdominalis was found at the adjacent water of Chindo at 0∼20m layer and the northern area beyond Chindo at 20m∼bottom layer. This fact suggested that the cold water mass existed at the adjacent waters of Chindo in summer.

김치 발효중 생체활성 아민 생성에 관한 연구

서일원,류춘선,이주돈,이영환,변광의 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2

Biogenic amines can be formed and degraded either as the result of endogenous amino acid decarboxylase activity in raw materials or by the growth of decarboxylase-positive microorgannisms under conditions favorable to enzyme activity. Three biogenic amines(Tryptamine, Histamine, Tyramine) were intensively investigated by the HPLC during Kimchi fermentation at 5℃. The patterns of microfloral changes in lactic acid bacterial group, Leuconostoc, Streptococcus and Lactobacillus, were similar to the typical low-temperature fermentation. The population of microbial growth were high after 10 days and gradually decreased. The levels of Tyramine were lowered(10mg/kg) during this mid-periods(8∼16 days) but very high in initial-(15mg/kg) and final-periods (30mg/kg), in which the total acidity ranged between 0.2∼0.35% and 0.4∼0.6%, while the acidity in mid-periods revealed 0.35∼0.4% beginning the initial ripening period. Leuconostoc was highly increased in number in mid-period but slightly declined as the acidity increased, whereas Streptococcus was highly distributed in initial-period and Lactobacillus in final-period. The levels of Tryptamine and Histamine were relatively low throughout the whole fermentation period, but the profile of Tryptamine level was very similar to the case of Tyramine. Histamine was maintained at a certain level after mid-period of fermentation.

가족성 고콜레스테롤혈증 유병자에서 HMG Co-A Reductasen Inhibitor 및 Bile Acid Resin의 투여로 인한 아킬레스건 황색종의 감소

채인호,한기훈,박영배,조주희,김효수,손대원,김철호,오병희,이명묵,최윤식,서정돈,이영우 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.9

삼출성 중이염 환자에서의 혈중 및 아데노이드 면역글로불린 E의 면역혈청학적 연구

장혁순,강성호,유창수,김성현,이병돈,박영진,윤세동,안희영,강주원 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1

Otitis media with effusion (OME) is one of the most common disease in children but its pathogenesis is not clear. In particular the role of allergy has revealed conflicting support with widely varing opinions as to its importance. Within recent years, striking biochemical and immunochemical analytic techniques have opened a new approach the study of otitis media with effusion. So we focused on distributions of IgE in adenoid tissue and serum IgE levels. Authors compared the serum IgE and the distribution of IgE in adenoid tissue between the 20 patients underwent tonsillectomy, adenoidectomy and ventilating tube insertion and control group of 11 patients underwent tonsillectomy and adenoidectomy. The results were as follows; 1. In the distribution of IgE in adenoid tissue, there was a significant increase in the group of patients with OME compared to the control group (P<0.01). 2. In the analysis of serum IgE levels, the levels of IgE in the OME patients an control group were higher than normal level, although the level of IgE in the OME patients were less than that of control group, there was no significance P>0.05).

Long-Term Survival and Tumor Recurrence of Patients with Superficial Esophageal Cancer after Complete, Non-Curative Endoscopic Resection: a Single Center Case Series

Ji Wan Lee,Charles J. Cho,Do Hoon Kim,Ji Yong Ahn,Jeong Hoon Lee,Kee Don Choi,Ho June Song,Sook Ryun Park,Hyun Joo Lee,Hyun Joo Lee,Gin Hyug Lee,Hwoon-Yong Jung,Sung-Bae Kim,Jong Hoon Kim,Seung-Il Par 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.5

Background/Aims: To report the long-term survival and tumor recurrence outcomes in patients with superficial esophageal cancer(SEC) after complete non-curative endoscopic resection (ER). Methods: We retrieved ER data for 24 patients with non-curatively resected SEC. Non-curative resection was defined as the presence ofsubmucosal and/or lymphovascular invasion on ER pathology. Relevant clinical and tumor-specific parameters were reviewed. Results: The mean age of the 24 study patients was 66.3±8.3 years. Ten patients were closely followed up without treatment, while14 received additional treatment. During a mean follow-up of 59.0±33.2 months, the 3- and 5-year survival rates of all cases were90.7% and 77.6%, respectively. The 5-year overall survival rates were 72.9% in the close observation group and 82.1% in the additionaltreatment group (p=0.958). The 5-year cumulative incidences of all cases of recurrence (25.0% vs. 43.3%, p=0.388), primary ECrecurrence (10.0% vs. 16.4%, p=0.558), and metachronous EC recurrence (16.7% vs. 26.7%, p=0.667) were similar between the twogroups. Conclusions: Patients with non-curatively resected SEC showed good long-term survival outcomes. Given the similar oncologicoutcomes, close observation may be an option with appropriate caution taken for patients who are medically unfit to receive additionaltherapy

Bortezomib, doxorubicin, and dexamethasone combination therapy followed by thalidomide and dexamethasone consolidation as a salvage treatment for relapsed or refractory multiple myeloma: analysis of efficacy and safety

Lee, Sung Sook,Suh, Cheolwon,Kim, Bong-Seog,Chung, Jooseop,Joo, Young-Don,Ryoo, Hun-Mo,Do, Young Rok,Jin, Jong-Youl,Kang, Hye Jin,Lee, Gyeong-Won,Lee, Moon Hee,Shim, Hyeok,Kim, Kihyun,Yoon, Sung-Soo,B Springer-Verlag 2010 Annals of hematology Vol.89 No.9