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효율적으로 방위각 이노베이션을 구하는 다중표적 방위각 추적 알고리즘
유창수,이장식,이균경,Ryu, Chang-Soo,Lee, Jang-Sik,Lee, Kyun-Kyung 대한전자공학회 2001 電子工學會論文誌-SC (System and control) Vol.38 No.6
최근에 Ryu 등은 추정된 신호부공간(signal subspace)으로부터 구한 방위각 이노베이션을 이용하여 다중표적의 방위각을 추적하는 알고리즘을 제안하였다. 이 알고리즘은 데이터를 연관시키면서 동시에 표적의 방위각을 구하기 때문에 기존의 추적 알고리즘과 달리 별도의 데이터연관 기법이 필요 없으며, 구조가 간단하다는 장점을 가지고 있다. 그러나 표적의 개수가 N일 때, 각 표적의 방위각 이노베이션을 구하기 위하여 차원이 (2N+1)${\times}$(2N+1)인 실행렬의 역행렬을 구하는 것이 필요하다. 본 논문에서는 표적의 조향벡터를 신호부공간에 투영할 때, 투영오차가 0이 된다는 사실로부터 방위각 이노베이션을 구하기 위한 새로운 선형 방정식을 제안하였다. 제안한 새로운 선형방정식은 Ryu의 알고리즘에서 사용하는 식과는 달리 한 개의 방위각 이노베이션만을 변수로 사용하기 때문에 역행렬을 구할 필요가 없고 효율적이다. Recently, Ryu et al. proposed a multiple target angle tracking algorithm using the angular innovation extracted from the estimated signal subspace. This algorithm obtains the angles of targets and associates data simultaneously. Therefore, it has a simple structure without data association problem. However it requires the calculation of the inverse of a real matrix with dimension (2N+1)${\times}$(2N+1) to obtain the angular innovations of N targets. In this paper, a new linear equation for angular innovation is proposed using the fact that the projection error is zero when the target steering vector is projected onto the signal subspace. As a result, the proposed algorithm dose not require the matrix inversion and is computationally efficient.
항균펩타이드인 Pexiganan (MSI-78) 과 모델 이중 지질막 간의 상호 작용으로생성되는 지질막 파괴에서 Resveratrol 분자의 영향
유창수,정준호,이동국 한국생체재료학회 2013 생체재료학회지 Vol.17 No.4
This study has investigated the effect of Resveratrol(3,5,4'-trihydroxy-trans-stilbene) on membrane fragmentation of model lipid bilayer membranes caused by the antimicrobial peptide, Pexiganan (MSI-78). Large unilamellar vesicles (LUVs) of 7:3 POPC/POPG has been used for the model cellular membrane in the study of interaction between biomolecules and lipid molecules. Recently, this model was used to investigate lipid composition-dependent membrane fragmentation and pore-forming mechanism of membrane disruption by Pexigan (MSI-78). Results showed that the peptide induces micelle-like fragments evidenced by the 31P NMR signal at 0 ppm compared to the typical powder pattern of unperturbed lipid bilayers. In the present study, Resveratrol molecules were added to the LUVs before the peptide was applied to them. 31P spectra were collected for each sample and monitored any changes in the 31p NMR spectra. Our observations show that resveratrol inhibits MSI-78 interaction to POPC/POPG lipid bilayer and protect the lipid membrane evidenced by the disappearance of the isotropic 31P NMR intensity near 0.0 ppm. We suggest that resveratrol binds to the surface of the POPC/POPG bilayers and alters the properties of the lipid membrane.
Polymerization-induced Self-assembly of Janus Bottlebrush Polymers
유창수,남지윤,서명은 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.1
Polymerization-induced self-assembly (PISA) has been recognized as a facile and effective strategy to prepare block copolymer-based nano assemblies in solution at high concentration. Here, we investigate PISA of Janus bottlebrush polymers by growing another side chain from a bottlebrush homopolymer in a selective solvent. A synthetic route to such Janus bottlebrush polymers and detailed polymerization kinetics will be presented. The in situ self-assembly behavior will be interpreted based on competition between backbone stiffness and interfacial tension.
유창수,남지윤,서명은 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
Polymerization-induced Self-Assembly (PISA) is a facile and versatile method for preparation of block polymer nanoparticles at high concentrations. So far, most PISA examples are based on linear diblock copolymer systems and investigation of architecture effect in PISA such as bottlebrush has been largely unexplored. Here, we report synthesis of Janus bottlebrush polymers by combination of grafting-through and grafting-from polymerizations, and PISA behavior in the grafting-from stage. This approach enables evaluating the effect of bottlebrush architecture compared to linear diblock PISA by varying the grafting number, which can be set in the grafting-through step. Synthetic details of the bottlebrush polymers and their self-assembly behavior will be discussed.