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      • KCI등재

        고로슬래그시멘트를 사용한 다공성 황토콘크리트의 성능 평가

        김황희,강수만,박종식,박상우,전지홍,이진형,차상선,박찬기,Kim, Hwang-Hee,Kang, Su-Man,Park, Jong-Sik,Park, Sang-Woo,Jeon, Ji-Hong,Lee, Jin-Hyung,Cha, Sang-Sun,Park, Chan-Gi 한국농공학회 2010 한국농공학회논문집 Vol.52 No.3

        This study aims to evaluate a porous concrete using hwang-toh, blast furnace slag and blast furnace slag (BFS) cement instead of type I cement. The tests that were carried out to analysis the properties of porous hwang-toh BFS cement concrete included compressive strength, continuous void ratio, absorption rate, and pH value, repeated freezing and thawing test were conducted. Test results indicated that the performance in porous hwang-toh concrete are effective on the kaoline based binder materials. The pH value were shown in about 9.5 ~ 8.5. The compressive strength was increased and void ratio was decreased with increasing the kaoline based binder materials, respectively. The void ratio and compressive strength were in the range of about 21 ~ 30 %, 8 ~ 13 MPa, respectively. The increased in void ratio of more than 25 % is showed to reduce the resistance of repeated freezing and thawing. Also, the resistance of repeated freezing of thawing and the compressive strength of porous hwang-toh BFS cement concrete are independent with hwang-toh content and BFS cement amount. But, the void ratio was decreased with increasing the high volume hwang-toh contents (more than 15 %).

      • KCI등재
      • 급성 골수성 백혈병 환자에서 관해 유도 항암 화학요법 후 발생한 베르니케 뇌증

        황진원,정재현,서광원,최병진,송영진,김종윤,이은지,임홍규,이상민 인제대학교 2009 仁濟醫學 Vol.30 No.-

        Wernicke's encephalopathy is characterized by the triad of ocular symptoms, ataxia, and mental confusion and neuropsychiatric condition generally caused by acute thiamine deficiency. Although it is common in the severe alcoholics, several other causes also have been identified, such as total parenteral nutrition (TPN) use, hyperemesis gravidarum, anorexia nervosa, hemodialysis, uremia, and acquired immunodeficiency syndrome(AIDS). Chemotherapy in patient with malignanacy and long term total parenteral nutrition following bone marrow transplantation are related with Wernicke's encephalopathy. A 48-year-old woman had been treated with Daunorubicin and Cytarabine for remission induction chemotherapy of acute myeloblastic leukemia and intravenous hyperalimentation due to persistent hematochezia and ileus caused by infiltration of leukemic cell in terminal ileum. She suddenly complained of diplopia, tremor, and mental confusion at 32th day after chemotherapy and generalized tonic-clonic seizure at 34th day after chemotherapy. The diagnosis of Wernicke's encephalopathy was made with clinical presentations and brain MRI. Brain MR T2-weighted & Flair image revealed a high signal intensity lesions bilaterally at the medial thalamus and peri-acueductal grey matter of the midbrain. The patient was successfully treated with vitamin B1. We presented a case of acute Wernicke's encephalopathy developed after remission induction chemotherapy followed by intravenous hyperalirnentation in a patient with acute myeloblastic leukemia.

      • KCI등재

        The expression patterns of RANKL and OPG in murine tooth eruption

        Hwang, Kyung-Mun,Kim, Eun-Jung,Kim, Hyun-Jung,,Kim, Young-Jin,Nam, Soon-Hyeun 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

        치아의 맹출은 치아기 (dental organ)와 치조골의 세포와 연관된 매우 복잡한 과정이다. 우선 치아 맹출이 일어나기 전에 파골세포가 치낭으로 집결하게 된다. 이러한 치낭의 역할은 파골세포와 조골세포의 상호작용으로 이루어 지는 골개조와 밀접한 관련이 있는데, 이는 치아 맹출과 연관된 많은 유전자들이 치낭에서 발현되기 때문이다. RANKL는 TNF ligand family로써 조골세포에 존재하며 파골세포의 형성 및 전구세포로 부터의 활성화를 유도한다. 이러한 RANKL은 OPG에 의해 그 작용이 억제되며 RANKL와 OPG의 상대적인 비율이 파골세포의 형성에 영향을 미친다. 또한 Runx2유전자의 변이는 조골세포의 분화와 활성에 차질을 가져오고 결국 RANKL/OPG pathway를 통해 파골세포 형성에 영향을 줄 수 있다. 치아의 발육 및 맹출에 미치는 RANKL 및 OPG의 영향을 알아보고 Runx2와의 연관성을 알아보기 위해 in situ hybridization 방법으로 태생 1, 3, 5, 7, 9, 11일된 쥐의 하악 및 제1대구치를 사용하여 실험을 실시한 결과 RANKL, OPG, Runx2의 mRNA가 태생 1일부터 11일까지 치낭 및 치아주위조직에 특성있게 나타났다. 이중 태생 5일에서 9일 사이에 RANKL 및 Runx2는 치아의 교합면측과 하방 치조골 부위의 발현이 강하게 나타난 반면 OPG는 약한 발현을 보였다. 이는 또한 파골세포의 활성부위를 알아보기 위해 TRAP염색을 실시하여 태생 5일에서 9일 사이에 최대의 활성화를 나타낸 결과와 연광성 있게 나타났다. RANKL, OPG, Runx2의 특성있는 발현양상들을 종합해 볼 때, 치아 맹출은 치낭, 치아기, 치조골 사이의 상호 작용을 통해 이루어 지며, 이는 치낭이 치아 맹출에 있어서 매우 중요하다는 것을 의미한다. 또한, 이러한 유전자들 (RANKL, OPG, Runx2) 이 치아의 맹출에 중요한 역할을 하는 것으로 사료된다. Tooth eruption is a complex and tightly regulated process that involves cells of the tooth organ and the surrounding alveolus. Osteoclast precursors must be recruited into the dental follicle prior to the onset of eruption. This function of dental follicle may be regarded as the ability of bone remodeling characterized by the interaction of osteoclasts and osteoblasts. This is because tooth eruption is a localized event in which many of the genes required for eruption are expressed in the dental follicle. RANKL is a membrane-bound protein that is a member of the TNF ligand family, which is present on bone marrow stromal cells and osteoblasts, and induces osteoclast formation and activation from precursor cell. The biologic effect of RANKL is inhibited by OPG and, in bone, the relative ratio of RANKL and OPG modulates osteoclastogenesis. To evaluate the roles of RANKL and OPG in tooth eruption and the relations with the expression pattern of Runx2, in situ hybridization was performed with mandibles of mice at postnatal stage 1, 3, 5, 7, 9 and 11. mRNA of RANKL, OPG, and Runx2 are expressed in dental follicle and surrounding tissue from P1 to 11. To determine the sites of osteoclastic activity duing tooth eruption, mandibles were dissected. Peak osteoclastic activity in alveolar bone along the occlusal and basal regions was observed from P5 to 9, with osteoclasts in these regions being large and strongly TRAP-positive. The specific spatic-temporal expression patterns of RANKL, OPG and Runx2 in our study suggest that tooth eruption could be progressed through the interactions of molecular signaling among dental follicle, dental organ and alveolar bone, furthermore it means that dental follicle is quite important in tooth eruption. In addition, it indicates that these genes (RANKL, OPG, and Runx2) play critical roles in tooth eruption.

      • KCI등재

        A Study on the Revitalization Model of Traditional Markets in Korea through typifying their decline factors

        Hwang,Suk-Hui,Kim,Jong-Jin 한국주거환경학회 2012 주거환경(한국주거환경학회논문집) Vol.10 No.3

        전통(재래)시장의 침체는 단순히 열악한 물리적환경과 소비자들의 소비형태의 변화만이 아니라 사회적, 물리적, 경제적, 문화적, 환경적부문의 쇠퇴가 함께 진행되면서 나타난 현상이라고 할 수 있다. 본 연구는 다양한 쇠퇴측면에서 접근하는 다계층 의사결정모형(AHP)을 구축하여 전통시장의 침체요인에 기반을 둔 활성화 방안을 도출하고자 하였다. 연구결과 전문가들은 소비자들의 유입을 통하여 시장 및 상인에게 경제적으로 도움이 될 수 있는 지원방안과 상가 및 상인들의 역량을 강화시키는 것이 전통시장 활성화에 큰 도움을 줄 것으로 인식하고 있었다. 세부적으로는, 전문가들은 현재 부분적으로 시행하고 있는 전통시장 상품권인 온누리상품권 유통확대, 전통시장의 통합적 운영조직 구성, 공동마케팅 운영, 셔틀버스의 운행을 통한 접근성 향상과 수변공간과 쉼터 등을 조성하여 쇼핑 환경을 향상시키는 것이 중요하다고 인식하고 있는 것으로 나타났다. 반면에 정부와 지방자치단체가 중점적으로 지원해온 문화적 측면의 재생방안 및 아케이드 설치, 보행로 정비등 물리적재생은 전통시장의 활성화에 큰 도움이 되지 않는 것으로 인식하고 있다. 따라서 전통시장의 효율적 활성화를 위해서는 상인역량강화 및 경제적재생 측면의 활성화를 중심으로 하는 방향으로의 전환이 필요한 것으로 나타났다.

      • KCI등재후보

        열전대(thermocouple)를 이용한 Buchanan Plugger 표면의 온도상승 분석

        조진숙,황윤찬,김선호,황인남,최보영,정영진,정우남,오원만 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.4

        This study was performed to evaluate the actual temperature rise on the surface of Buchanan plugger using thermocouple. The heat carrier system 'System B Heatsource'(Model 1005, Analytic Technologies, Redmond, WA, USA) and the Buchanan pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200℃ on digital display and the power level on it was set to 10. Five thermocouples were placed in direct contact with the surface of each size of Buchanan's pluggers at 1 mm increments from the tip to the 4 mm length of shank. The heat control spring was touched for 5 seconds, and temperature rise on the surface of the pluggers were measured at 1 sec intervals for more than 5 seconds with an accuracy of 0.01 using Data Logger. The data were statistically analyzed by one-way ANOVA. The results were as follows. 1. The position at which the temperature peaked was approximately at 1~2 mm far from the tip of Buchanan plugger (p<0.01). 2. The peak temperature was 215.25±2.28℃ in F plugger, 185.94±2.19℃ in FM plugger, 169.51±9.12℃ in M plugger, and 160.79±1.27℃ in ML plugger and the peak temperature was highest in F plugger and followed by, in descending order, FM plugger, M plugger. ML plugger showed the lowest peak temperature (p<0.01). 3. The temperature on the pluggers was decreased with the increase of touching time. This results suggest that the actual temperature on the surface of the pluggers dose not correlate well with the temperature set on digital display. Heat concentrates around the up. The larger plugger reveals lower temperature rise relatively.

      • 한국 근해안강망어업의 조석에 따른 주간 어황변동 추세 분석

        김진영,황진수,임양재,홍승현,연인자,황학진,김지연 한국수산자원학회 2003 한국수산자원학회지 Vol.6 No.-

        조류의 강세에 의존하여 조업이 이루어지는 근해안 강망어업의 어황이 조석에 따라 어떻게 변동하는지를 연구하기 위하여 1994년부터 1996년까지 주간 어획량, 조업척수, 척당어획량의 자료를 판매량이 증가하는 조금 전후와 그 반대의 현상이 나타나는 사리 등으로 구분하여 시계열분석기벅으로 장기변동추세를 분석하였다. 단계별 구분에 따른 어획량에 대한 분석결과, 3단계 구분에서 전체적으로 모형의 적합도가 가장 높게 나타났다. 3단계로 구분한 경우의 어획량은 조금에 (1-0.6891B+2.1168B²)(1-B)Z₁=(1-0.9730B)a_(?) 사리에 Z_(t)=(1+0.41659B)a_(t₁) 중간물에 (1+1.38253B+0.63391B²)Z₁-(1+1.15390B+0.64547B²)Z₁-(1+1.15390B+0.64547B²)a_(t)로 표현되었으며, 조업척수는 조금에 (1-0.19699B)Z₁=(1-0.66259B)a_(t?) 사리에 (1+0.45672B)Z₁=1+0.006094B)a_(t?) 중간물에(1.0.74814B) Z₁=((1-0.21476b)a_(t)로 표현되었다. 척당어획량은 조금에 (1-0.54709B+0.26967B^(6))Z_(t)=a_(t₁) 사리에 (1-0.26622B-0.28067B^(6))(1+0.45081B^(8))Z_(t)=(I+0.21652B^(15))a 중간물에 (1-0.23881B-0.10487B^(5))Z_(t)=a_(t)로 나타낼 수 있었다. Z_(t)는 시간 t에서의 어획량, 조업척수, 척당 어획량을 나타낸다. B는 후향연산자 로서 ㅇ?P를 들면 B^(d)를 Z_(t)에 작용시키면 Z_(t-d)이 된다. A seasonal Autoregressive Integrated Moving Average (ARIMA) time series model was applied to the weekly prediction of landings. number of operating boats and catches per unit effort of large stow net fisheries as ebb and flow in Korean wafers for 1994-1996. The estimated seasonal ARIMA models are presented as the fellowing equations:(1-0.6891B+2.1168B²)(1-B)Z₁=(1-(0.9730B)a₁ at the neap tides. Z₁=(1+0.41659B)a₁ at the spring tides, and (1+1.38253B+0.63391B²) Z₁=(1+1.15390B+0.64547B²)a₁ at the middle tides between the neap tide and the spring tide fer landings.(1-0.19699B) Z₁=(1-0.662593)a₁ at the neap tides. (1+0.45672B) Z₁=(1+D.0.006094B)a₁ at the spring tides, and (1-0.74814B) Z₁=(1-0.214766)a₁ at the middle tides between the neap tide and the spring tide for the number or operating boats, and(1-0.54709B+0.26967B)Z₁=a₁at the neap tides, (1-0.26622B-0.28067B^(6))(1+0.45081B^(8)) Z₁=(1+0.21652B^(15))a₁ at the spring tides, and (1-0.23881B-0.10487B^(5)) Z₁=a₁t the middle tides between the neap tide and the spring tide for the catch per unit efforts, where: :Z_(t)=the value at week t: B^(D)=a backward shift operator that is used as follows: B^(D)Z_(t)=-Z_(t-p); and a_(t)=error term at week t. The prediction error by the Box-Cox transformation on weekly landings, number of operating boats and CPUB of stow net in Korea were less than that by the Iogarithmic transformation.

      • Thermocouple을 이용한 Buchanan Plugger 표면의 온도상승 분석

        조진숙,황윤찬,김선호,황인남,최보영,정영진,정우남,오원만 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.4

        This study was performed to confirm the actual temperature rise on the surface of Buchanan plugger by evaluating the temperature rise on the surface of it, the peak temperature of pluggers of various size using thermocouple. The heat carrier system 'System B Heatsource' (Model 1005, Analytic Technologies, USA) and the Buchanan pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200 which Dr. Buchanan's "Continuous wave of condensation" technique recommended on digital display and the power level on it was set to 10. The touch mode was used. Five thermocouples were placed in direct contact with the surface of each size of Buchanan's pluggers at 1 ㎜ increments from the tip to the 4 ㎜ length of shank. Each thermocouple was secured with cyanoacrylate adhesive and orthodontic resin block. The two wire leads of each thermocouple were connected to the appropriate channels of Data Logger. This was configured to simultaneously record input from the five thermocouples. The heat control spring was touched for 1, 2, 3, 4 and 5 seconds, and the temperature rise on the surface of the pluggers were measured at 1 sec intervals for more than 5 seconds with an accuracy of 0.01. Ten trials was determined for each plugger. The average of temperature rise and standard deviation was calculated for each size of plugger. The data were statistically analyzed by one-way ANOVA to determine their significance. The results as follows. 1. The position at which the temperature peaked was approximately at 1∼2㎜ far from the tip of Buchanan plugger (p<0.01). 2. The peak temperature was 215.25±2.28℃ in F plugger, 185.94±2.19℃ in FM plugger, 169.51±9.12℃ in M plugger, and 160.79±1.27℃ in ML plugger and the peak temperature was highest in F type and followed by, in descending order, FM type, M type. ML type showed the lowest peak temperature (p<0.01). This results suggest that the actual temperature on the surface of the pluggers does not correlate well with the temperature set on digital display. Heat concentrates around the tip. The larger plugger reveals lower temperature rise relatively.

      • KCI등재

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