우유에서 분리된 포도상구균속 세균의 항생제 감수성

김지훈,고문주,김가희,이승훈,최성숙,Kim, Ji-Hoon,Ko, Mun-Joo,Kim, Ka-Hee,Lee, Seung-Hoon,Choi, Sung-Sook 한국미생물학회 2010 미생물학회지 Vol.46 No.4

The prevalence and antimicrobial susceptibilities of Staphylococcal isolates from bovine milk samples were assessed. From January 2009 to October 2009, a total 287 bovine milk samples were randomly collected from 15 stock raising farms located in northern area of Kyunggi province and cultured for the presence of Staphylococci spp. A total 79 staphylococcal isolates were recovered from the milk samples. The predominant isolates were S. aureus (43.03%) and S. chromogenes (24.05%). Antimicrobial resistance patterns of 79 Staphylococcal isolates against ampicillin, chloramphenicol, ciprofloxacin, erythromycin, gentamicin, oxacillin, teicoplanin, tetracyclin, and vancomycin were tested. Staphylococcal isolates revealed the highest resistance to ampicillin (56.96%) and oxacillin (39.23%). Of 31 oxacillin resistance strains, 8 strains carry mecA gene which is responsible for methicillin resistance.

인접전류패턴을 사용한 변형된 방향 대수적 영상복원법

김지훈,김찬용,김경연,최봉열,Kim, Ji Hoon,Kim, Chan Yong,Kim, Kyung Youn,Choi, Bong Yeol 대한전자공학회 2012 전자공학회논문지 Vol.50 No.8

전기 임피던스 단층촬영법(electrical impedance tomography, EIT)에서 관심 대상물 내부 영상을 복원하는 방법 중 하나인 방향 대수적 영상복원법(directional algebraic reconstruction technique, DART)은 삼각함수형태로 설계된 전류패턴을 외부 전극에 인가하고 이로부터 얻어지는 전압과의 상관관계를 이용하여 영상복원 알고리즘의 입력인 각 전극사이의 저항을 유도하게 된다. 이때, 저항유도 시간이 발생하고 이는 DART 알고리즘을 실시간 영상복원에 적용하는데 장애가 되고 있다. 이 논문에서는 저항유도 시간의 문제를 해결하기 위하여 기존에 사용하던 삼각함수형태의 전류패턴대신 인접전류패턴을 사용한 변형된 방향 대수적 영상복원법(modified directional algebraic reconstruction technique, mDART)을 제안한다. 제안한 방법은 주입한 전류와 측정된 전압으로부터 저항을 유도하지 않고 측정전압을 바로 복원 알고리즘의 입력으로 사용하기 때문에 DART의 영상복원시간의 대부분을 차지하는 저항유도 시간을 없앨 수 있을 뿐만 아니라 인접전류패턴을 사용하여 복원영상의 질도 향상시킬 수 있다. 이 논문의 타당성을 입증하기 위하여 모의실험을 수행하였으며 제안한 방법은 기존 방법보다 복원시간의 개선뿐만 아니라 영상오차 관점에서도 성능이 개선됨을 확인하였다. The directional algebraic reconstruction technique (DART) using the trigonometric current pattern is one of the image reconstruction algorithms in electrical impedance tomography (EIT). This method needs to compute resistances between electrode pairs as using relation between the injected currents and measured voltages for the reconstruction of the inner image. The delay time is incurred in this process. Therefore this paper proposes modified directional algebraic reconstruction technique (mDART) using the adjacent current pattern instead of the trigonometric current pattern to solve the delay time for initial resistance values. The proposed method uses measured voltages instead of computed resistances in the reconstruction algorithm. Hence this method can eliminate the delay time because it does not use the resistances. In conclusion, the proposed method improves image quality and image reconstruction time by using the adjacent current pattern. To prove performance of the proposed method, we carried on computer simulation of various cases.

후포분지 홀로세 퇴적물의 유기물에 대한 지화학 분석 결과 및 의미

김지훈,박명호,공기수,한현철,정태진,최지영,김진호,강무희,이치원,오재호,Kim, Ji-Hoon,Park, Myong-Ho,Kong, Gee-Soo,Han, Hyun-Chul,Cheong, Tae-Jin,Choi, Ji-Young,Kim, Jin-Ho,Kang, Moo-Hee,Lee, Chi-Won,Oh, Jae-Ho 대한자원환경지질학회 2010 자원환경지질 Vol.43 No.1

Geochemical approaches on the two recovered piston cores were performed to understand the characteristics of organic matters and the influence of the sea level variation of the East Sea in the Hupo Basin since the Holocene. The analyzing results on organic components (TOC and TN), and isotopic compositions of organic matters showed the variation to core locations and sampling depths. In core 08HZP-01, their values were gradually changed with depth from 4 mbsf to seafloor. However, rapid variation was observed at the boundary of 4.71 mbsf (meter below seafloor) in core 08HZP-03. Based on TOC/TN, $\delta^{13}C_{org}$ and $\delta^{15}N_{org}$, the origin of organic matters in the Hupo Basin can be divided into three groups; 1) predominant marine algae, 2) $C_3$ land plant, and 3) mixture of $C_3$ land plant and marine/freshwater algae. It is likely that the vertical and spatial variations of organic and isotopic compositions reflect the shifts in sedimentary environment (including sediment transportation) by ocean currents and sea-level changes and others during the Holocene period.

소아 궤양성 대장염의 수술적 치료 성적

김지훈,김현영,정성은,박귀원,김우기,Kim, Ji-Hoon,Kim, Hyun-Young,Jung, Sung-Eun,Park, Kwi-Won,Kim, Woo-Ki 대한소아외과학회 2005 소아외과 Vol.11 No.2

Ulcerative colitis, an inflammatory bowel disease, is primarily managed medically with a combination of 5-ASA and steroids. However, this chronic disease requires surgical management if symptoms persist or complications develop despite medical management. The clinical course, indications and outcome of surgical management of 21 patients under the age of 15 who were endoscopically diagnosed with ulcerative colitis at the Seoul National University Children's Hospital between January, 1988 and January, 2003 were reviewed. Mean follow up period was 3 years and 10 months. The mean age was 10.3 years old. All patients received medical management after diagnosis and 8 patients (38 %) eventually required surgical management. Of 13 patients who received medical management only, 7 patients (53 %) showed remission, 4 patients are still on medical management, and 2 patients expired due to congenital immune deficiency and hepatic failure as a result of sclerosing cholangitis. In 8 patients who received surgical management, the indications for operation were, 1 patient sigmoid colon perforation and 7 patients intractability despite medical management. The perforated case had a segmental colon resection and the other 7 patients underwent total colectomy with ileal pouch-anal anastomosis. One patient expired postoperatively due to pneumonia and sepsis. and 1 is still on medical management because of mild persistent hematochezia after surgery. Six other operated patients are doing well without medical therapy. Pediatric ulcerative colitis patients can be surgically managed if the patient is intractable to medical management or if complications such as perforation are present. Total colectomy & ileal pouch-anal anastomosis is thought to be the adequate surgical method.

김제시 간척지역 천부 지하수내 철 환원작용 특성에 대한 고찰

김지훈,정태진,류종식,김락현,Kim, Ji-Hoon,Cheong, Tae-Jin,Ryu, Jong-Sik,Kim, Rak-Hyeon 대한자원환경지질학회 2013 자원환경지질 Vol.46 No.1

The study area is located on the western coastal region of Korea, partly had been reclaimed lands. Groundwaters of the coastal area show lower Eh and DO values (Eh: 0.57 V ${\rightarrow}$ 0.13 V, DO; 9.7 mg/l ${\rightarrow}$ 1.3 mg/l), and higher Fe concentrations (> 20 mg/l) than those of the inner land (< 0.3 mg/l), indicating that the redox condition of groundwater changes from oxic into suboxic/anoxic conditions as it flows from the inland toward the coastal area. In addition, Fe speciation of groundwater from the coastal area demonstrates that the most dissolved Fe exist as $Fe^{2+}$, reflecting that groundwater is under the anoxic condition to sufficiently occur Fe reduction. According to the result of Fe extraction with the sediment samples from three wells (A, B, C), the sediments provide enough $Fe^{3+}$ to occur the Fe reduction in the groundwater. Integrated all results of the groundwater and sediment, we infer that the Fe reduction to occur in groundwater is associated with the reclamation processes of the study area.

혈액질환에 속발하는 이차성 위암

김지훈,지성배,허훈,진형민,김욱,김동욱,이종욱,민우성,김춘추,전해명,Kim, Ji-Hoon,Jee, Sung-Bae,Huh, Hoon,Chin, Hyung-Min,Kim, Wook,Kim, Dong-Wook,Lee, Jong-Wook,Min, Woo-Sung,Kim, Choon-Choo,Jeon, Hae-Myung 대한위암학회 2007 대한위암학회지 Vol.7 No.4

Purpose: Patients with hematologic diseases such as chronic myeloid leukemia (CML) or chronic lymphoid leukemia (CLL) are known to have an increased chance of acquiring a secondary neoplasm. Stomach cancer is one of the most common malignant diseases in Korea, and we investigated whether the incidence of secondary stomach cancer in patients with a hematologic disease increases, in order to determine if a more intensive screening program for detecting secondary gastric cancer was required. We also investigated the safety of performing a gastrectomy in hematologic disease patients. Materials and Methods: From 1992 to 2006, the medical records of 8376 patients diagnosed with one of the six common hematologic diseases were reviewed. Results: Nine secondary stomach cancers were found among the 8376 patients during the 15-year observation period. No surgical-related complications occurred, and there was no recurrence of stomach cancer if detected early. Conclusion: It seems that a more intensive screening program for detecting secondary gastric cancer in hematologic disease patients is not required, and surgery is not risky in these patients.

근위부 위절제술 후 재건 술식에 따른 경과 관찰

김지훈,육정환,김병식,오성태,Kim, Ji-Hoon,Yook, Jeong-Hwan,Kim, Byung-Sik,Oh, Sung-Tae 대한위암학회 2006 대한위암학회지 Vol.6 No.1

Purpose: A proximal gastrectomy is performed for gastric cancer in the upper part of the stomach to preserve the function of the stomach after surgery. An esophagogastrostomy is one of the common reconstruction methods for a proximal gastrectomy, but this method results in a high incidence of reflux esophagitis. This study was undertaken to compare subjective and functional results between esophagogastrostomy and jejunal interposition reconstructions. Materials and Methods: From June 1998 to December 2002, proximal gastrectomies were performed in 33 patients with tumors in the upper third of the stomach; 8 had reconstruction using jejunal interposition between the esophagus and the remnant stomach (JI group) while 25 had reconstruction using esophagogastrostomy (EG group). The postroperative courses of the patients were reviewed in terms of symptoms, weight changes, and endoscopic findings. Results: The mean age of the patients was 59 years; 26 were men and 7 were women. There were no significant differences in general complications, operating times, or histologic features between the two groups. Fifty-two percent (52%) of the EG group complained of dysphagia, and 16% them experienced heartburn and acid belching. Twelve percent (12%) of the JI group complained of dysphagia, but heartburn and acid belching did not occur. Incidences of reflux esphagitis (36%) and balloon dilatation for anastomotic stricture (16%) were more common in the EG group than in the JI group (0% and 12%). Conclusion: To prevent or minimize complications, such as reflux esophagitis and postoperative symptoms, a proximal gastrectomy with a jejunal interposition is an alternative method as an organ-preserving surgical strategy to improve quality of life for patients. (J Korean Gastric Cancer Assoc 2006;6:1-5)

말초성 안면신경마비의 한양방 협진치료에 관한 임상적 연구

김지훈,송재준,홍승욱,Kim, Ji-Hoon,Song, Jae-Jun,Hong, Seung-Ug 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.1

Objectives : Facial palsy is not uncommon disease and most patients with facial palsy are peripheral type, as in Bell' s palsy. In western medicine, oral steroid is the mainstay of the treatment. Recently, oriental-western treatment became one of the alternative modality for the treatment of the facial palsy. However, the treatment result and the degree of patient' s satisfaction were not evaluated. In this study, we tried to characterize the clinical characteristics, short-term recovery rate and degree of patient' s satisfaction after oriental-western medicine treatment on facial palsy of peripheral type. Methods : Between May 2008 and December 2008, we examined 16 patients who presented with facial palsy of peripheral type in Dongguk University Medical Center. Clinical characteristics and recovery rate was analyzed by retrospective chart review. The degree of patient' s satisfaction was measured by 5 point scale. Results : The causes of facial palsy were Bell' s palsy (87.5%) and the Ramsay-Hunt syndrome (12.5%). The highest age groups of facial palsy were 6th and 7th decades. Most frequent accompanying symptom was postauricular pain. After oriental-western medicine treatment, 10 patients (62.5%) showed recovery of facial palsy better than House-Brackmann grade 2. 11 patients (68.8%) were satisfied with the oriental-western medicine treatment. Conclusions : Considering the degree of patient' s satisfaction and treatment result, we believe that oriental-western treatment could be safe and reliable protocol for the treatment of facial nerve palsy of peripheral type.

후두 결핵의 임상 양상 분석: 최근 10년간 단일 기관의 경험

김지훈,공태훈,최홍식,변형권,Kim, Ji-Hoon,Kong, Tae Hoon,Choi, Hong-Shik,Byeon, Hyung Kwon 대한후두음성언어의학회 2020 대한후두음성언어의학회지 Vol.31 No.2

Background and Objectives The overall incidence of laryngeal tuberculosis (LT) has generally decreased over the recent years, yet there is still a discrete population of patients newly diagnosed with the disease. This study is aimed to examine the patients with LT over the recent 10 years and to investigate the changes in clinical pattern with respect to the past period. Materials and Method A retrospective review has been performed on 20 patients who have been initially diagnosed with LT between 2005 and 2015. Results The age of the patients ranged from 25 years to 95 years with an average age of 45.6 years. Seventeen patients (85%) showed hoarseness, which was the most common clinical symptom. Most affected lesion was the true vocal cord. Laryngoscopic examination showed various clinical manifestations: polypoid 30%, granulomatous 25%, nonspecific 25%, ulcerative 20%. A variety of methods were used for diagnostic confirmation of LT [acid-fast bacilli (AFB) smear 45%, AFB culture 40%, polymerase chain reaction 30%, surgical pathology 45%]. Coexisting pulmonary tuberculosis (PT) was detected in 10 patients (50%). Relative to the patients with inactive PT or normal lung status, those with active PT showed higher incidence of laryngeal lesions located in areas other than true vocal cord (p=0.050). Conclusion Based on the analytic results from this study, laryngologists should recognize the changes in the recent clinical patterns of LT and always be ready for clinical suspicion of this disease on such atypical laryngeal findings which can often mimic laryngeal malignancies to provide the pertinent treatment.

작업치료사의 직업윤리와 교육에 대한 인식이 직무스트레스와 직무몰입에 미치는 영향

김지훈,정재훈,Kim, Ji Hoon,Jung, Jae Hun 한국디지털정책학회 2021 디지털융복합연구 Vol.19 No.10

본 연구는 작업치료사의 직업윤리와 교육에 대한 인식이 직무스트레스와 직무몰입에 미치는 영향을 파악하기 위한 조사연구이다. 이를 위하여 작업치료사 173명을 대상으로 직업윤리와 교육에 대한 인식, 직무스트레스와 직무몰입을 평가하였으며, 본 연구의 결과는 다음과 같다. 첫째, 직업윤리와 교육에 대한 인식, 직무스트레스와 직무몰입(p<.01) 간에는 유의한 상관관계가 있었다. 둘째, 직업윤리와 교육에 대한 인식의 하위요인 중 교육경험(p<.01)과 윤리문제의 심각성(p<.05)은 직무스트레스에 영향을 미치는 것으로 나타났다. 셋째, 직업윤리와 교육에 대한 인식의 하위요인 중 교육경험(p<.05)은 직무몰입에 영향을 미치는 것으로 나타났다. 본 연구의 결과들을 통하여 직업윤리의 중요성을 인식하고, 이를 향상하기 위한 체계적인 교육이 필요할 것이다. The aimed of this research was to identify the influence of perception of the vocational ethics and education on job stress and job commitment in occupational therapists. 173 occupational therapists measure for perception of vocational ethics and education, job stress and job commitment, the findings of the study were as follows. First, perception of vocational ethics and education was correlated with job stress, job commitment(p<.01). Second, perception of vocational ethics and education sub-factor of education experience(p<.01), seriousness of ethical issues(p<.05) was found to have affected the job stress. Third, perception of vocational ethics and education sub-factor of education experience(p<.05) was found to have affected the job commitment. Through the results of this study, systematic education will be needed to recognize the importance of vocational ethics and improve it.