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PGSFR중간열교환기의 정상상태 고온 구조 건전성 평가
이성현,구경회,김성균,Lee, Seong-Hyeon,Koo, Gyeong-Hoi,Kim, Sung-Kyun 한국압력기기공학회 2016 한국압력기기공학회 논문집 Vol.12 No.1
Four cylindrically shaped IHXs(Intermediate Heat Exchangers) are installed in the PHTS(Primary Heat Transfer System) of the PGSFR(Prototype Gen IV Sodium cooled Fast Reactor). As for the IHX, the temperature difference of structure is inevitable result caused by heat transfer between primary coolant sodium and IHTS(Intermediate Heat Transport System) sodium. It is necessary to evaluate the high temperature structural integrity of IHXs which operate at the elevated temperature condition over the creep temperature. In this paper, the high temperature structural integrity of IHX under assumed loading conditions has been reviewed according to ASME code.
이성현 한국중국현대문학학회 2015 中國現代文學 Vol.0 No.74
Dianshizhai Pictorial 點石齋畵報 launched in May 8th, 1884 in Shanghai, China, covered various subjects ranging from politics, society, diplomacy, new Western civilizations, popular culture to everyday life, folk religions and custom. So far, research on Dianshizhai Pictorial has evolved around these various subject topics. More importantly, previous studies on Dianshizhai Pictorial have tended to focus on the subjects primarily related to the Western civilizations and its modernity due to their strong interest in the issue of modernity. As the result, subjects which are considered strange and weird from the present point of view have been excluded from this branch of the Pictorial studies. My paper focuses on the two factors that have been overlooked by previous Pictorial studies: the form and the strangeness of its subject matters. More specifically, I analyze the peculiar characteristics of the Pictorial as a medium in terms of the strangeness of its topics. The main focus of analysis is an article titled “銅人跨海” (A Statue Standing across the Sea). Particularly, I examine how various European and Chinese traditions are overlaid in its illustration and the accompanied article intervening in its meaning and form. Seven Wonders of the World, especially Colossus of Rhodes, 17th century European cartography, Ferdinand Verbiest’s The Kunyu tushuo 坤輿圖說 in early Qing dynasty will be suggested and analyzed as the examples of such traditions multiply embedded in the article. Throughout the examination, I ultimately demonstrate how Dianshizhai Pictorial uses old forms to represent new knowledge on the things whose specific images are not accessible and therefore hard to imagine. The phenomenon of histrorical pseudomorphosis, a phenomenon by which old and familar forms are deployed to accomodate new knowledge and information is characteristic in the experience of Chinese modernity; the powerful and time-honored Chinese traditional culture played a crucial role in accommodating new knowledge and information from the Western civilization. And it is this phenomenon of historical pseudomorphosis that defines the peculiar characteristics of the Pictorial as a media. Unknown things represented by familar forms yield curious weirdness both in terms of the forms and the contents. And this curiosity was in fact one of the essential elements that constitute Chinese experience of the modernity.
CFD 분석에 의한 느타리버섯 재배사 환경균일성 향상 연구
이성현,유병기,이찬중,임영택 한국버섯학회 2017 한국버섯학회지 Vol.15 No.1
The oyster mushroom cultivation house typically has multiple layers of growing shelves that cause the disturbance of air circulation inside the mushroom house. Due to this instability in the internal environment, growth distinction occurs according to the area of the growing shelves. It is known that minimal air circulation around the mushroom cap facilitates the metabolism of mushrooms and improves their quality. For the purpose of this study, a CFD analysis FLUENT R16 has been carried out to improve the internal environment uniformity of the oyster mushroom cultivation house. It is found that installing a section of the working passage towards the ceiling is to maintain the internal environment uniformity of the oyster mushroom cultivation house. When all the environment control equipment – including a unit cooler, an inlet fan, an outlet fan, an air circulation fan, and a humidifier – were operated simultaneously, the reported Root Mean Square (RMS) valuation the growing shelves were as follows: velocity 23.86%, temperature 6.08%, and humidity 2.72%. However, when only a unit cooler and an air circulation fan operated, improved RMS values on the growing shelves were reported as follows: velocity 23.54%, temperature 0.51%, and humidity 0.41%. Therefore, in order to maintain the internal environment uniformity of the mushroom cultivation house, it is essential to reduce the overall operating time of the inlet fan, outlet fan, and humidifier, while simultaneously appropriately manage the internal environment by using a unit cooler and an air circulation fan.
이성현 충북대학교 의과대학 충북대학교 의학연구소 1998 忠北醫大學術誌 Vol.8 No.1
연구목적 : 약물 난치성 간질환자의 임상적 특성을 파악하고 약물 난치성 간질로 이행할 가능성을 높인다고 제시된 인자들을 재평가함으로써 간질환자를 처음 대하였을 때 예후를 예측하고, 치료방침을 정하는데 도움을 얻고자 이 연구를 시행하였다. 대상 및 방법 : 충북대학교 병원 신경과의 간질환자 등록지에 등록된 간질 환자 중 조사 시점에서 전문가에 의해 악물 치료를 받은 경력이 2년 이상이면서 한 달에 최소한 1회 이상 발작이 있는 23명의 약물 난치성 간질 환자를 대상으로 하였다. 이들의 임상양상(발병연령, 발착의 빈도, 발작 유형, 간질 증후군 등)과 약물 난치성 간질로 이행할 가능성을 높이는 것으로 제시된 인자 중 중추신경계 내의 해부학적 병변의 존재 유무, 뇌파소견상의 이상 소견, 신경학적 결손 등의 빈도를 조사하였다. 결과 : 약물 난치성 간질환자는 충북대학교 병원 신경과의 간질환자 등록지에 등록되어 투약을 받고있는 317명의 환자 중 23명으로 7.3%였다. 최초 발작의 평균 발생연령은 16세였고, 대부분이 독립적인 생활이 불가능한 상태로 주위의 도움을 필요로 하였으며, 2개에서 6개(평균 3.5개)의 항경련제가 시도되었다. 부분발작이 21명(91.3%)으로 압도적으로 많았고 전신발작은 2명(8.7%)에 불과하였다. 부분발작 중 단순부분발작이 8명(38.1%)이었고, 복합부분발작이 13명(61.9%)이었다. 간질 증후군에 따른 분류에서는 증후성 간질이 15명(65.2%), 잠재형 간질이 7명(30.4%), 특발성 간질은 1명(4.4%)이었다. MRI 혹은 CT상의 국소적 병변은 18명(78.3%)에서 발견되었는데, 허혈성 뇌병변으로 생각되는 경우가 6례로 가장 많았고 이 중 5례는 주산기 허혈성 뇌손상이 원인으로 생각되었다. 그 밖에 외상성 뇌병변이 3명, 해마위축이 3명, 동정맥 기형이 2명, 기타의 원인 4명 등이었다. 21명(91.3%)의 뇌파에서 이상소견이 발견되었고, 신경학적 결손은 12명(52.2%)에서 관찰되었는데 정신지체가 8명으로 가장 빈번하게 존재하는 이상 소견이었다. 결론 : 중추신경계 내의 국소성 병변의 존재, 뇌파상의 이상 소견, 신경학적 결손 특히 정신지체의 존재 등은 약물 난치성 간질로 이행할 가능성을 높이는 인자로 생각된다. 따라서, 이러한 소견을 갖고있는 환자는 약물 난치성이 될 가능성이 높음을 예측할 수 있고 치료 초기에 대상이 되는 경우 수술과 같은 좀 더 적극적인 치료를 고려하는 것이 필요하다. Purpose : To know the clinical characteristics of the patients with medically intractable epilepsy and evaluate the factors known to increase the possibility of intractability, I performed this study. Materials and Methods : I analysed clinical characteristics(onset age, seizure frequency, seizure type, epilepsy syndrome, etc.) and the variables(the presence of focal lesion on brain MRl or CT, abnormalities in EEG, and focal neurologic deficits) proposed to increase the possibility of medical intractability in the 23 patients with medically intractable epilepsy in the epilepsy registry of the department of neurology, Chungbuk National University Hospital. All 23 patients had been treated for more than 2 years by specialists and had at least 1 seizure per month. Results : The patients with medical intractable epilepsy were 23 (7.3%) of the 317 patients in the registry. Mean onset age of seizure was 16, most patients could not live independently, and 2 to 6(mean : 3.5) antiepileptic drugs had been tried. Patients with partial seizures were 21 (91.3%) and those with generalized seizures only 2 (8.7%). Among the patients with partial seizures 8 (38.1%) patients had simple partial seizures and 13 (61.9%) complex partial seizures. In the epilepsy syndrome classification symptomatic seizures were 15 (65.2%), cryptogenic 7 (30.4%), idiopathic 1(4.4%). In the 18 patients (78.3%), brain MRI or CT revealed focal lesions : ischemic lesions in 6 patients ; traumatic lesions 3 patients ; hippocampal atrophy 3 patients ; arterio-venous malformation 2 patients ; and other lesions 4 patients. Twenty-one (91.3%) had some abnormalities in EEG and 12(52.2%) had focal neurologic signs among which mental retardation (8 patients) was most frequent. Conclusion : This study suggests that the presence of focal lesions in the brain, abnormalities in EEG, and focal neurologic signs especially mental retardation might be the factors to increase the possibility of medical intractability. Therefore, when we treat epilepsy patients with these variables it is advisable to consider more active treatment in early stage such as epilepsy surgery if it is indicated.
느타리 병버섯 재배사 원격환경 모니터링 및 제어시스템 개발
이성현,유병기,이찬중,윤남규 한국버섯학회 2017 한국버섯학회지 Vol.15 No.3
This study was carried out to develop the technology to manage the growth of mushrooms, which were cultivated based on long-term information obtained from quantified data. In this study, hardware that monitored and controlled the growth environment of the mushroom cultivation house was developed. An algorithm was also developed to grow mushrooms automatically. Environmental management for the growth of mushrooms was carried out using cultivation sites, computers, and smart phones. To manage the environment of the mushroom cultivation house, the environmental management data from farmers cultivating the highest quality mushrooms in Korea were collected and a growth management database was created. On the basis of the database value, the management environment for the test cultivar (hukthali) was controlled at 0.5 °C with 3–7% relative humidity and 10% carbon dioxide concentration. As a result, it was possible to produce mushrooms that were almost similar to those cultivated in farms with the best available technology.
Kainic acid로 유발된 경련에 의한 해마의 손상과정에서 nimodipine의 신경세포 보호효과
이성현,서중배,이호승 충북대학교 의학연구소 2000 忠北醫大學術誌 Vol.10 No.1
연구목적: 경련에 의해 해마의 신경세포가 사멸하는 과정에서 칼슘이 관여한다는 것이 알려져 왔다. 따라서 칼슘통로 차단약물인 nimodipine 이 이러한 과정에서 신경세포 보호효과가 있을 것이라고 가정할 수 있으며 흰쥐의 kainic acid (KA) 간질모델에서 이 가설을 검증하고자 하였다. 재료 및 방법: 특정무균 수컷 Sprague-Dawley 흰쥐를 무작위로 A (5 마리), B (5 마리), 및 대조군(2 마리)으로 나누었다. A군 흰쥐에게는 40㎎/㎏의 nimodipine을 복강내로 주사하고 30분 후에 age-specific dose의 KA를 복강내로 주사하였다. B군에게는 대신에 동량의 생리식염수를 주사한 다음 30분 후에 KA를 주사하였다. 대조군에게는 nimodipine과 KA 대신에 생리식염수를 주사하였다. KA를 주사한 후 발작의 일어나는 시간과 지속시간을 관찰하였고, 3일이 경과한 다음 희생시켜 헤마톡실린-에오신 염색으로 해마의 병리를 관찰하였다. 결과: A, B군의 흰쥐는 모두에서 발작과 해마의 신경세포사가 관찰되었다. A군에서 alternate limb scratching이 나타난 시간이 51.0±4.2 분으로, B군 흰쥐의 26.6±5.5 분에 비하여 늦었고(p=0.008) 지속시간도 짧은 경향이 관찰되었다. 또한 A군에서 더 많은 해마 신경세포가 살아남아 있음이 관찰되었다. 한편, 대조군의 흰쥐에서는 경련이 관찰되지 않았고, 해마도 정상이었다. 결론: 본 실험결과에 의하면 칼슘통로봉쇄약물인 nimodipine은 KA 간질모델에서 항경련 효과 및 신경세포보호 효과가 있는 것으로 사료된다. Purpose: It has been known that seizure-induced hippocampal neuronal death was partly mediated by the Ca2+ influx, We performed this study to investigate the effect of calcium channel blocker, nimodipine in preventing hippocampal neuronal death caused by kainic acid (KA)-induced seizures. Materials and Methods: Specific pathogen-free, Sprague-Dawley male rats were assigned randomly to one of three groups: (ⅰ) A group (n=5), (ⅱ) B group (n=5), and (ⅲ) control group (n=2). The A group received an intraperitoneal injection of nimodipine (40㎎/㎏) and an age-specific dose of KA 30 minutes later. The B group received an injection consisting of a volume of saline and the same dose of KA. Control rats were injected with equal volumes of saline instead of nimodipine and KA. After the KA injection, the latency and duration of each KA seizure was observed. Three days later the rats were sacrificed for hematoxylin and eosin staining of the hippocampus. Results: all rats of the A and the B groups showed prolonged seizures and hippocampal neuronal degeneration. In the A group, seizures were milder and more hippocampal neurons were spared. Control rats showed no seizure and hippocampal neuronal degeneration. Conclusion: These results suggest that calcium channel blocker nimodipine have cell protecting effect during the hippocampal neuronal degeneration caused by KA-induced seizures.
당뇨병환자의 신기능 평가지표로서 혈청 Cystatin C 측정의 유용성
이성현,안균열,정옥연,박영진,장숙진,문대수 대한진단검사의학회 2005 Annals of Laboratory Medicine Vol.25 No.3
Background : Diabetic nephropathy is the most frequent complication in patients with diabetes mellitus (DM). In clinical practice, the glomerular filtration rate (GFR) is often estimated from serum creatinine. Recently, serum cystatin C has been suggested being a better parameter for diagnosis of impaired renal function. We evaluated serum cystatin C as a potential new marker of GFR in diabetes patients. Methods : Serum cystatin C and serum creatinine (sCr) were measured in 73 DM patients to evaluate their usefulness in diabetic patients. DM patients were divided into three groups (whole DM patients, albuminuric patients, and DM patients with sCr<1 mg/dL). Serum cystatin C and sCr were compared with creatinine clearance (CCr). Results : The overall correlation coefficient for the reciprocal of serum cystatin C was superior to that of the reciprocal of serum creatinine in all three patient groups. With CCr cut-off values of 60 mL/min and 80 mL/min, receiver operating characteristic (ROC) plotting demonstrated that serum cystatin C had a higher sensitivity and specificity for detecting decreased GFR than did serum creatinine in all three patient groups. Conclusions : These findings suggest that serum cystatin C is superior to serum creatinine as a marker of GFR measured by correction or mean ROC-plot AUC in diabetic patients; therefore, serum cystatin C could be used for the early detection of the impairment of renal function. 배경 : 당뇨병성 신증은 당뇨병 환자의 가장 흔하게 발생하는합병증 중의 하나이다. 현재 임상에서 사구체 여과율을 평가하기위한 지표로서 혈청 크레아티닌을 사용하고 있지만, 최근에 사구체 여과율을 반영하는 새로운 지표인 cystatin C가 소개되었다. 이에 본 연구에서는 당뇨병 환자에서 혈청 cystaitn C의 유용성에 대해 평가해보고자 하였다.방법 : 73명의 당뇨병 환자에서 혈청 크레아티닌과 혈청 cystatinC를 측정하였으며, 실험 환자군은 전체 당뇨병 환자군, 알부민뇨증을 보이는 당뇨병 환자군, 혈청 크레아티닌이 정상인 당뇨병 환자군으로 나누었다. 세 가지 환자군에서 각각 혈청 cystatin C, 혈청 크레아티닌, 24시간 요를 이용하여 산정된 크레아티닌 청소율을 기 준 으 로 서 로 비 교 하 였 다 .결과 : 모든 세 환자군에서 혈청 cystatin C가 혈청 크레아티닌보다 높은 상관계수를 보였다. 사구체 여과율의 역치를 60 mL/min과 80 mL/min 2가지로 설정하여 ROC 곡선 분석을 하였을때 세 환자군에서 모두 혈청 cystatin C가 혈청 크레아티닌 보다,민감도와 특이도가 더 높은 값을 보였다. 결론 : 이러한 결과로 볼 때 당뇨병 환자군에서 사구체 여과율을 반영하는 지표로서 혈청 cystatin C가 혈청 크레아티닌보다 조기에 신기능 저하를 찾아내는데 유용하게 이용될 것이다.
Hierarchical FSM과 Synchronous Dataflow Model을 이용한 재구성 가능한 SoC의 설계
李成賢,최기영,劉承周 대한전자공학회 2003 電子工學會論文誌-SD (Semiconductor and devices) Vol.40 No.8
본 논문은 최근에 많이 사용되는 정형 계산 모델 중 하나인 hierarchical FSM (HFSM)과 synchronous dataflow (SDF) 모델(줄여서 HFSM-SDF)을 이용한 재구성 가능한 SoC 설계에서 실시간 구성 스케줄링(configuration scheduling) 방법을 제시한다. HFSM-SDF 모델을 이용한 재구성 가능한 SoC 설계에서는 HFSM이 갖는 동적인 특성들(예를 들면, AND 관계에 의해 동시에 일어나는 state transition, HFSM이 갖는 복잡한 control flow, 그리고 그에 따른 SDF actor firing의 복잡한 스케줄 등)로 인해 구성 스케줄링이 어려운 일이 된다. 그리고 이러한 동적인 특성들로 인해 정적인 구성 스케줄링 방법을 이용해서는 구성에 의한 지연(configuration latency)을 적절히 감추는 것이 어렵다. 본 논문에서는, 이 문제를 해결하기 위해, 실시간에 정확한 구성 순서를 찾은 후, 이를 이용한 동적인 구성 스케줄링 방법을 제안한다. 우선, 실시간에 필요한 구성 순서를 찾기 위해서는, HFSM-SDF 모델이 갖는 특징, 즉, SDF actor들의 실행 순서(firing schedule)는 최상위 FSM의 state transition 직전에 알 수 있다는 점을 이용할 수 있다. 이렇게 최상위 FSM의 매 transition마다 SDF actor들의 구성 순서를 찾아, ready configuration queue(ready CQ)에 저장한 후에, 전체 시스템의 state transition을 수행하며, 이 과정에서 FPGA에 (기존에 FPGA를 점유하고 있던 SDF actor의 종료 등으로 인해) 공간이 남으면, 실시간 구성 스케줄러는 ready CQ를 살펴보고, 필요한 구성을 다운로드한다. 본 논문에서 제시한 실시간 구성 방법을 MPEG4의 natural video decoder와 IS95의 modem 예제에 적용해 본 결과, 수행 시간이 최대 21.8%까지 향상되었으며 메모리 사용의 부담은 무시할 수 있을 정도였다. We present a method of runtime configuration scheduling in reconfigurable SoC design. As a model of computation, we use a popular formal model of computation, hierarchical FSM (HFSM) with synchronous dataflow (SDF) model, in short, HFSM-SDF model. In reconfigurable SoC design with HFSM-SDF model, the problem of configuration scheduling becomes challenging due to the dynamic behavior of the system such as concurrent execution of state transitions (by AND relation), complex control flow (HFSM), and complex schedules of SDF actor firing. This makes it hard to hide configuration latency efficiently with compile-time static configuration scheduling. To resolve the problem, it is necessary to know the exact order of required configurations during runtime and to perform runtime configuration scheduling. To obtain the exact order of configurations, we exploit the inherent property of HFSM-SDF that the execution order of SDF actors can be determined before executing the state transition of top FSM. After obtaining the order information and storing it in the ready configuration queue (ready CQ), we execute the state transition. During the execution, whenever there is FPGA resource available, a new configuration is selected from the ready CQ and fetched by the runtime configuration scheduler. We applied the method to an MPEG4 decoder and IS95 design and obtained up to 21.8% improvement in system runtime with a negligible overhead of memory usage.
韓國의 勞動組合 및 임시직고용이 製造業의 經濟的 安全性에 미치는 效果에 關한 硏究
이성현,이근수 안성산업대학교 1998 論文集 Vol.30 No.2
This paper explores the hypothesis that temporary work and unions play a distinct role in the adjustment strategies of firms in the face of economic shocks. The economic role of unions are to enhance workers’ welfare, for example, to raise wage and improve working conditions by monopolizing the labor supply and seizing the power of collective bargaining against a specific firm, and their demands’ legitimization could be obtained by providing something for their firms. For these, unions must also make efforts for the purpose of yielding their firms’ profits and increasing productivity. Therefore, when unions and firms are coexistent, the welfare of unions as well as that of firms could be maximized. In this case, whether unions have a positive or negative influence upon economic safety of firms become important issues in appraising the unions’ economic functions. However, when we look into the effects of unions temporary work on economic safety through an empirical study, we must pay attention to a point that organization of union itself is not a exdogenous but endogenous variable. Finally, the results lends support to the notion that temporary work and unions provide an important source of economic safety in some manufacturing in Korea.