ImmunoDot법에 의한 전신성 류마티스 질환의 자가항체 검사

박성환,김선준,김성일,민준기,이상헌,홍연식,조철수,김호연 최신의학사 1997 最新醫學 Vol.40 No.7

한국인의 심근 조직내 카드뮴 농도의 참고치

박정덕,임헌방,최병선,권일훈,이상연,강은용,홍연표,장임원 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.1

Cadmium(Cd) is an ubiquitous, toxic and nonessential metal which is controversial about the association with a cardiovascular disease. In this study, we investigated the reference level of Cd in myocardium in Korean general population. The level of Cd and zinc(Zn) concentration in myocardium of 252 cases of "sudden and unexpected death" autopsies (male: 172, female : 60) aged 0 to 87 years was analyzed. The concentration of Cd and Zn was determined with atomic absorption spectrophotometer(Perkin-Elmer Model 5100) by flameless and flame method, respectively. The content of Cd and Zn in myocardium showed the log-normal distribution rather than normal distribution. Geometric mean concentration of Cd was 0.19 ㎍/g wet weight in myocardium. The level of Cd in myocardium was not significantly different between male (0.18㎍/g wet weight) and female (0.22㎍/g wet weight). Geometric mean concentration of Zn in myocardium was 25.25 ㎍/g wet weight. The level of Zn between male (25.13 ㎍/g wet weight) and female (25.57㎍/g wet weight) was not different. The deposit of Cd in myocardium was age-dependent of biphasic pattern, but the Zn level by age was not significantly different. The level of Cd in myocardium was increased to the fifties of age, thereafter a leveling-off was shown. The regression model of Cd deposit in myocardium by age was predicted as the following equation: Log Heart-Cd= -1.2726 + 0.0234 ·Age -0.0002 ·Age². The maximum Cd deposit in myocardium was estimated to be 0.26 ㎍/g wet weight at the age of 58.5 in Korean general population. In addition, the total Cd burden in heart by age was predicted as a following equation: Total Cd burden in Heart= -10.165+2.891 ·Age -0.0258 ·Age². The maximum heart burden of Cd was estimated to be 70.7㎍ at age of 55.4. The positive correlation between Cd and Zn was observed in myocardium. The linear regression equation was Log Heart-Zn = 1.4195+0.0262 ·Log Heart-Cd.

초등학생의 1000m 달리기-걷기 평가방법에 관한 연구

박철호,박은경,고봉민,우상헌,안민호,차유림 東亞大學校附設스포츠科學硏究所 2002 스포츠科學硏究論文集 Vol.20 No.-

This research aims to develop a new evuluation method of endurance for elementary school students. The norm of the event of 1,000m running-walking was examined and reviewed. As a result, a new highly-valid norm for the present 1,000m running-walking was made. Among the 5th and 6th graders, 2,144 pupils were chosen. The subjects were given 1,000m running-walking and step test. The new norm led to the following results: 1. The frequency distribution of PEI according to Cajori's 5-stage evaluation method turned out to be normal for both 5th and 6th graders. In conclusion, this new norm of 1,000m running-walking is believed to provide more valid and credible scores for elementary school students. The 1,000m running-walking records and the PEI will be used as the basic data for foretelling one's endurance.

PVDF 압전소자 활용 전기 에너지 수집

"이수헌", "여인권", "정재성", "박종대" 배재대학교 자연과학연구소 2015 自然科學論文集 Vol.26 No.1

PVDF(Polyvinylidene Fluoride)를 사용하여 진동에너지를 전기적 에너지로 수집할 수 있는 소형 발전시스템을 개발하였다. 개발된 시스템은 온도, 진동, 압력 등의 데이터를 수집하고 무선으로 전송하는 센서 네트워크의 전원으로 사용될 수 있다. We have developed a small electrical energy harvesting system using PVDF(Polyvinylidene Fluoride) which can convert vibrational energy into electrical energy. The developed system can be used as a power source for sensor network which acquire data such as temperature, vibration, pressure, etc and transmit data to a data center

접착제의 다층적용이 복합레진의 전단결합강도에 미치는 영향

박헌동,이난영,이창섭,이상호 대한소아치과학회 2006 大韓小兒齒科學會誌 Vol.33 No.3

Midazolam의 경비투여와 경구투여 시 진정효과에 대한 비교연구

박헌동,이창섭,이상호,이난영 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

Midazolam은 현재 치과에서 널리 사용되고 있는 의식하 진정용 약물이다. 그러나 주로 경비투여로 사용될 뿐 경구투여 특히 소아에서 경구투여에 대한지침이 없어 본 연구를 통해 midazolam의 경구투여 시 진정효과에 대해 알아보고자 하였다. 전신상태가 양호하며 2회 이상의 치료가 필요한 남아 15명, 여아 13명, 총 28명의 환아를 대상으로 midazolam (Dormicum??, Roche)을 경비투여(0.2mg/kg)와 경구투여 (0.5mg/kg)하여 치과치료를 시행한 후 치료과정을 6단계로 구분하여 각 단계별로 수면지수와 울음지수, 움직임지수, 전반적인 행동지수를 측정, 비교하여 다음과 같은 결과를 얻었다. 1. 전체 치료과정동안 수면지수와 울음지수, 움직임지수, 전반적인 행동지수 비교 시 Ⅰ군 (경비투여)과 Ⅱ군(경구투여) 사이에 유의한 차이가 없었다(p>0.05). 2. 보호자 설문조사 결과 Ⅰ군에서는 67.8%의 보호자가 투여 시 아이가 고통스러워한다고 답하였으며 Ⅱ군에서는 17.8%의 보호자가 투여에 어려움이 있다고 답하였다. 3. 귀가 후 행동양상에 대한 질문에서 '평상시와 비슷하다'가 Ⅰ군에서는 78.6%, Ⅱ군에서는 57.1%로 경비투여 시 더 빠른 회복을 보이는 것으로 나타났다. 위와 같은 결과를 종합하여 볼 때 midazolam의 경구투여는 경비투여와 유사한 적절한 진정효과를 가지면서 환자에게 더 잘 받아들여지는 투여방법으로 생각된다. The purpose of present study was to compare the sedative effect of intranasal and oral midazolam treatment. The study was conducted on twenty eight child patients who required at least two visits. All the patients showed a good physical status (ASA-I). The patient was randomly assigned to receive midazolam either intranasal (Group Ⅰ, 0.25 mg/kg) or oral (Group Ⅱ, 0.5mg/kg) route at each visit. Treatment procedure was divided into six stages. In each stage, sleep score, crying score, movement score and overall behavior score were evaluated. The overall results can be summarized as follows: 1. Through all treatment procedures, no significant difference was observed between Group Ⅰ and Group Ⅱ in terms of sleep, crying, movement and overall behavior index. 2. In a questionnaire to the parents, 67.8% of parents answered that the child suffered at intranasal administration, while only 17.7% of parents responded the same way at oral administration. 3. In a questionnaire regarding patients' behavior at home after midazolam treatment, 'Similar to normal behavior was 78.6% in Group Ⅰ and 57.1% in Group Ⅱ, indicating that intranasal treatment of midazolam may be more effective for the recovery.

장기간의 40분 달리기 운동이 비만학생의 호흡순환능력과 혈청 지질에 미치는 영향

박철호,고봉민,박은경,우상헌,안민호 동아대학교 스포츠과학연구소 2000 스포츠科學硏究論文集 Vol.18 No.-

The purpose of study was to investigate the effect of 12wks before and after running exercise of obsese in D high school in Pusan city, exercise group(7) performed 12wks running exercise and control group(7), before and after subjects performed the maximal exercise test on treadmill's 12wks running exercise. Through the comparision and analysis of change respiro-circulatory and serum lipids the results of this study were as follows. 1. In 12wks before and after running exercise, physique and body composition of exercise group was found to have a great decrease in %Fat(6%), Fat(kg)(6%), Triceps(7%) and to have a significant in crease in %LBM(6%). 2. Respiro-circulatory Capacity of exorcise group at the maximal exercise, was found to have a great decrese in VE(5%), RR(8%), RQ(5%). 3. In 12wks before and after running exercise at rest time, in seam lipids of exercise group was found to have a great decrease in TC(8%), TG(29%), LDL-C(7%) and to have a significant in crease in HDL-C(20%), FFA(74%). 4. At rest time, the control group was found to have a little decrease in TG, HDL-C, LDL-C and to have little change in TC and FFA. 5. In 12wks before and after running exercise at the maximal exercise, in serum lipids of the exercise group was found to have significant decrease in TC(18%), TG(23%) and to have a significant in crease in HDL-C(20%), LDL-C(25%), FFA(23%) and TG and HDL-C were found to have a significant change. 6. At maximal exercise, was found to have little change in the control group.

고강도 저항성 운동이 24시간 평균동맥압과 심박수에 미치는 영향

박철호,우상헌 東亞大學校附設스포츠科學硏究所 2002 스포츠科學硏究論文集 Vol.20 No.-

As this study is to examine the effect of resistance exercise, it was made an experiment on resistance-trained group which conducted more than three times a week during 12 weeks and high-intensity resistance exercise of once during 60 minutes in the object of a young man in his 20s with normotensive and irregular exercise habit. After the exercise, MAP and heart rate(HR) during 24-h were changed as the following results. 1. On rest HR of resistance-trained group compared with non-trained group were significantly(p<.05) low, MAP of resistance-trained group compared with non-trained group were low but they were not significantly different. 2. The change of 24-h HR in resistance-trained group both resistance exercise day and control day didn't have the significant difference in all sections. 3. 24-h HR of non-trained group was significantly(p<.05) low between 9AM to 1PM on resistance exercise day compared with control day. 4. On control day, HR of resistance-trained group compared with non-trained group were significantly(p<.05) low between 9AM to 1PM. 5. On resistance exercise day, 24-h HR of resistance-trained group compared with non-trained group were significantly(p<.05) low, 24-h MAP is significantly(p<.05) high between 9AM to 1PM. In conclusion, rest heart rate(RHR) of resistance trained group were significantly(p<.05) low compared with mean, cardiovascular's function of resistance trained group compared with non-trained group were good. In all comparisons, 24-h heart rate(HR) and MAP were similar patterns, it showed they didn't have an influence on the change of 24-h blood pressure(BP) no matter how resistance exercise may be executed.

콩의 개화기전후 공급과 수용부위의 무기영양성분함량 및 흡수량에 대한 질소의 효과

박재홍,송범헌,이철원,손석용,김홍식,박상일 忠北大學校 農業科學硏究所 2002 農業科學硏究 Vol.19 No.-

This study was conducted to examine the nitrogen effects on the uptaken amounts and utilization of mineral nutrients between source and sink tissues at major growth stages before and after the flowering stage with different nitrogen levels Hwangkeum cultivar(Glycine max L Mereill) was cultivated under five different mtrogen levels, 0, 2, 4, 6, 8 N kg/10a Comparing contents of total-N with different plant tissues at major growth stages before and after the flowering, total-N contents of leaves was gradually decreased from the flowering to the beginning maturity, while it of pod was continuously increased from the full seed to the beginning maturity Total-N content was higher in the treatment of 4 N Kg/10a that those of others The uptaken amount of N determined with different growth stage was rapidly increased maturity Higher proportion of uptaken N were into the leaves at the full seed stage, and they were transported from the leaves into pod at the beginning maturity stage Comparing major mineral elements of the leaves and the pod with different N leaves, in case of the leaves, the content of Fe, Mn, and Zn was decreased throughout the growth stages, whereas the content of Ca and Mg was decreased from the flowering to the full seed and then it was increased after the full seed stage In case of pod, the content of K, Fe, Mn, Zn, and Na was decreased from the flowering to the beginning maturity, while contest of Mg was increased.

타리비드 정(오플록사신 100㎎)에 대한 파비드 정의 생물학적동등성

박완수,조성희,이헌우,임호택,홍성제,서성훈,류재환,이경태 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.1

The purpose of the present study was designed to evaluate the bioequivalence of two ofloxacin tablets, Tarivid (Jell Pharm. Co., Ltd.) and Favid (ILHWA Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Twenty-four normal male volunteers, 23.67±3.12 year in age and 68.50±7.23 kg in body weight, were divided into two groups and a randomized 2x2 cross-over study was employed. After four tablets containing 100 mg of ofloxacin were orally administered, blood was taken at predetermined time intervals and concentrations of ofloxacin in plasma were deter mined using HPLC. Pharmacokinetic parameters such as AUC_(t) and T_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t), and C_(max) and untransformed T_(max). There were no sequence effects between two formulations in these parameters. The 90% confidence intervals for the log transformed data were acceptance range of log 0.8 to log 1.25 (e.g., log 0.94-log 1.04 and log 0.90-log 1.07 for AUC_(t) and C_(max) respectively). The major parameters. AUC_(t) and C_(max) met the criteria of KDFA for bioequivalence indicating that Favid tablet is bioequivalent to Tarivid tablet.