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박철호,오상엽 한국정보기술학회 2023 한국정보기술학회논문지 Vol.21 No.6
IP movement support is based on terminal operation to recognize mobility while moving and maintain a continuous communication session. The main content of the paper is that the proposed HMIPv6 aims to reduce the delay time of location updates because of movement of MH. This paper in order to work out the problem that can cause excessive traffic and long delay, IP address locations are stored in geographically distributed mobility management servers, and when a request comes in, it is proposed to request information from the nearest server. By doing so, performance was improved by utilizing packet transmission through an optimized path. In the proposed method of this paper, if the average interaction CNs increases, the mobility location update cost extends. However, due to the hierarchical structure using the Mobility Management Server, the location update cost () showed an average decrease of 12.8%. As a result, it is shown that the suggested method effectively lessen the cost compared to the existing method despite the high packet forwarding cost and not high mobility location update cost.
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Inflammasome-Dependent Peroxiredoxin 2 Secretion Induces the Classical Complement Pathway Activation
박철호,이현숙,곽만섭,신전수 대한면역학회 2021 Immune Network Vol.21 No.5
Peroxiredoxins (Prxs) are ubiquitously expressed peroxidases that reduce hydrogen peroxide or alkyl peroxide production in cells. Prxs are released from cells in response to various stress conditions, and they function as damage-associated molecular pattern molecules. However, the secretory mechanism of Prxs and their roles have not been elucidated. Thus, we aimed to determine whether inflammasome activation is a secretory mechanism of Prxs and subsequently identify the effect of the secreted Prxs on activation of the classical complement pathway. Using J774A.1, a murine macrophage cell line, we demonstrated that NLRP3 inflammasome activation induces Prx1, Prx2, Prx5, and Prx6 secretion in a caspase-1 dependent manner. Using HEK293T cells with a transfection system, we revealed that the release of Prx1 and Prx2 relies on gasdermin-D (GSDMD)-mediated secretion. Next, we confirmed the binding of both Prx1 and Prx2 to C1q; however, only Prx2 could induce the C1q-mediated classical complement pathway activation. Collectively, our results suggest that inflammasome activation is a secretory mechanism of Prxs and that GSDMD is a mediator of their secretion. Moreover, secreted Prx1 and Prx2 bind with C1q, but only Prx2 mediates the classical complement pathway activation.
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박철호,김경희,김찬주,김주영 대한운동학회 2024 아시아 운동학 학술지 Vol.26 No.4
OBJECTIVES The aim of this study was to investigate hydration awareness among youth baseball players and the effect of sports nutrition education on hydration-related indicators. METHODS Eighty-two youth baseball players who participated in a winter training camp hosted by the Korea Baseball Organization (KBO) participated in this study. A questionnaire was used to assess hydration awareness, and sports nutrition education focused on hydration-related topics was implemented. Hydration-related indicators such as fluid intake and urine color were measured to determine the effect of sports nutrition education. RESULTS Although the hydration awareness of youth baseball players was low, sports nutrition education had a positive effect on changes in fluid intake and urine color during the training camp. CONCLUSIONS Sports nutrition education should be actively implemented in the field to improve hydration awareness and status among youth baseball players.
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고령자 낙상에 의한 응급 상황의 4족 로봇 기반 알리미 시스템 설계 및 구현
박철호,임동하,김남호,유윤섭,Park, ChulHo,Lim, DongHa,Kim, Nam Ho,Yu, YunSeop 한국정보통신학회 2013 한국정보통신학회논문지 Vol.17 No.4
In this paper, we introduce a quadruped robot-based alarm system for monitoring the emergency situation due to falling in the elderly. Quadruped robot includes the FPGA Board(Field Programmable Gate Array) applying a red-color tracking algorithm. To detect a falling of the elderly, a sensor node is worn on chest and accelerations and angular velocities measured by the sensor node are transferred to quadruped robot, and then the emergency signal is transmitted to manager if a fall is detected. Manager controls the robot and then he judges the situation by monitoring the real-time images transmitted from the robot. If emergency situation is decided by the manager, he calls 119. When the fall detection system using only sensor nodes is used, sensitivity of 100% and specificity of 98.98% were measured. Using the combination of the fall detection system and portable camera (robot), the emergency situation was detected to 100 %.
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한우에서 $PGF_{2{\alpha}}$ 투여에 의한 발정유도 후 난소 구조물 및 호르몬의 변화와 수태율
박철호,류재선,유대중,박인철,김종택,서국현,오기석,손창호,Park, Chul-Ho,Ryu, Jae-Sun,Yu, Dae-Jung,Park, In-Chul,Kim, Jong-Taek,Suh, Guk-Hyun,Oh, Ki-Seok,Son, Chang-Ho 한국수정란이식학회 2012 한국동물생명공학회지 Vol.27 No.3
This study was carried out to develop the useful inducing method of estrus for Korean native cows. Under the condition of estrus induction by administering $PGF_{2{\alpha}}$ for the cows in which corpus luteum (CL) in ovaries was detected by ultrasonography, ovarian responses and the changes of progesterone ($P_4$) concentration against $PGF_{2{\alpha}}$ compared with conception rate were observed in cows and heifers. In inducing estrus administering $PGF_{2{\alpha}}$. to the cows which has corpus luteum in ovaries, ovarian reponses, the changes of progesterone concentration, and conception rate were identified and compared. The results attained from the studies were as follows. Significant decreases of CL in size over time after $PGF_{2{\alpha}}$ administration were detected in both cow and heifer groups (p<0.001), but not different between groups in the CL regression rate (p>0.05). In addition, the percentage changes relative to the plasma $P_4$ concentration on day 1 after $PGF_{2{\alpha}}$ treatment were decreased to below 1ng/ml. The growth rate of follicle was observed as 31% on day 1 and 42% on day 2 in cows, and 34% on day 1 and 97% on day 2 in heifers, resulting that growth of heifers are faster than that of cows (p<0.05). The conception rate after $PGF_{2{\alpha}}$ treatment were 60.5% and 64.2% in cows and heifers, respectively. It also indicated that the conception rate after estrus observation with $PGF_{2{\alpha}}$ injection was as high as 66.6% while that with timed-artificial insemination (TAI) regardless of the estrus observation was 56%, which means the pregnancy rate of artificial insemination after estrus observation was higher than that of TAI (p<0.05). In the result of all above, there were significant decreases in CL size and the plasma $P_4$ concentration by days but rapid growth in follicles, which has no differences in cows and heifers. The conception rate was commonly high after estrus observation and more than 50% under TAI.
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