노인 위암의 임상 병리학적 특징 및 Helicobacter pylori 감염

김혜랑,문영수,박영숙 凡石學術奬學財團 1999 凡石學術論文集 Vol.3 No.-

만성 신부전 환자에서 과도한 수분섭취로 유발된 심한 저나트륨혈증 1예

문기원,권순길,김혜영 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

만성 신부전에서는 사구체 여과율이 감소함에 따라 농축능은 손상되지만 희석능은 오랜 기간 유지되기 때문에 심한 저나트륨혈증은 잘 발생하지 않는 것으로 알려져 있다. 저자들은 잘못된 민간 의료지식으로 인하여 만성 신부전 환자에서 과도한 수분섭취로 유발된 심한 저나트륨혈증을 합병증 없이 치료한 증례를 경험한 바 있어 보고하는 바이다. Hyponatremia is one of the most common electrolytes imbalances in clinical medicine. However, it may be fatal if not corrected appropriately. In pre-dialytic chronic renal failure patients, severe hyponatremia is rare, because the dilutional capacity of the nephron is well preserved despite of diminished glomerular filtration rate. We report a case of severe hyponatremia induced by excessive water intake in a 33-year-old woman with chronic renal failure, treated successfully with diuretics and 3% saline. She had drunken 2-3 liters of free water daily for 7 days, and nausea, vomiting and dyspnea were developed 2 days later. At admission, serum sodium concentration was 103 mEq/L and serum creatinine was 4.7 mg/dL. Salt and free water intake were restricted and furosemide was administered intravenously, but serum sodium concentration rose only by 2 mEq/L. Then, 3% saline was added and serum sodium concentration rose to 118 mEq/L after 48 hours. On 7th hospital days, serum sodium concentration was 132 mEq/L, the patient discharged without any complication at all.

외식업 경영주의 직업만족도 및 경영의식 조사연구 : 경남지역을 중심으로 Focused Mainly in the Gyeong-nam Area

윤지영,문혜경 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

The purpose of this research was to analyze the job satisfaction and business attitudes of restaurant owners in order to explore solutions for improving restaurant management. The results were as follows:1) The motive for starting a restaurant business was vocational aptitude → possibilities → good income:2) In terms of job satisfaction, most respondents were satisfied with both the work itself and the income. It was also observed that the younger owners were more satisfied with their jobs than the older owners:3) Increased costs, including labor and food costs, was indicated as the biggest problem in restaurant management. Respondents also perceived labor shortage as one of the most difficult problems. Men were more likely than women to consider the following problems as being more serious: rent, financial problems, taxes, regulation restrictions, menu development and customer complaints. It was found that as the size of the restaurants grew, the respondents perceived the shortage of labor as the hardest part of running a business:4) Respondents agreed that employing good foodservice workers was the most important part of foodservice management. Owners also believed that they needed more research time for menu and service development:5) To be successful, the restaurant owners paid the most careful attention to food taste. Service, sanitation, and menu development were also emphasized. Respondents stressed the focus on service, good relationships, diligence, and faithfulness in order to be a good restaurant owner. The results of this research suggest that restaurant owners should have more professional conscientiousness to succeed in their own businesses, as well as improve the quality of the foodservice industry. Other important aspects related to the overall improved quality of the foodservice industry are: the continuation of government support, the enlargement of educational opportunities and greater respect for foodservice employees.

난소 기형종에 동반된 직장후방 기형종

오보영,이령아,구혜수,문혜성 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

‘병동 중심의 처치수가 산정지침 개발’ 등을 통한 간호업무 표준화 및 그 효과

한혜정,설미진,김영주,박소영,박아리스,문한경,이현영 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.1

문제: 병동 처치수가 산정 부정확 및 누락으로 인한 부적절한 재고관리로 진료차질, 불필요한 업무발생 및 수익이 감소한다. 목적: 병동 처치수가 산정 정확화를 위한 업무 표준화 도구 및 시스템을 개발하여 적정 재고관리를 통한 수익증대 및 직무만족도를 향상시킨다. 의료기관: 서울시 종로구에 소재한 대학병원 질 향상 활동: 병동중심의 처치 산정지침 개발 및 수가물품의 적정재고 관리방안을 모색하였다. 개선효과: 병동중심의 처치수가 산정 지침서를 제작하여 업무표준화를 기하였음. 응급청구 품목 및 수량이 ’07년 대비 71%감소하고 타 병동 차용품목이 활동 전에 비해 61% 감소, 수량은 77% 감소함. 응급청구 총소요시간이 활동 전에 비해 ’07년 대비 77% 감소하고 타 병동 차용 총 소요시간이 61% 감소함. 전년 동기간 대비 수익이 4% 증가하였으며 또한 54병동과 보험 심사팀에서 직원들의 직무만족도가 향상되었다.

교정용 미니 임플랜트 고정원과 SWA en masse sliding retraction 시 전치부 치축 조절 요인에 관한 유한요소해석

정혜심,성상진,문윤식,조영수,임승민 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.5

교정용 미니 임플랜트 고정원을 이용한 교정 치료가 보편화되며, SWA와 이를 이용한 en masse sliding retraction은 임상에서 흔히 사용하는 치료법이 되었다. 그러나 고정원을 성공적으로 보존하려는 노력에 비해, 발치 공간 폐쇄 시 전치부 치축 조절에 관여하는 요인에 대한 보고는 아직까지 부족한 실정이다. 본 연구에서는 제1소구치를 제거한 상악 치아와 치주 인대 그리고 치조골에 대한 3차원 유한요소 기준모델을 제작하였고, 제1대구치와 제2소구치 사이 주호선 10 mm 상방에 식립된 교정용 미니 임플랜트를 고정원으로 사용할 경우, 측절치-견치 사이의 견인 훅의 높이를 변화시키며 후상방 견인력을 가하거나, 주호선에 보상 만곡을 부여하는 것이 전치부 치축 조절에 어떤 영향을 미치는지 시뮬레이션 하였다. 또한 전치부 치축이 설측 경사된 모델을 같은 실험 조건으로 시뮬레이션 하여 발치 공간 폐쇄 시 설측 경사된 전치부 치축을 유지하거나 개선할 수 있는 요인을 검토하였고, 다음과 같은 연구 결과를 얻었다. 2 mm 높이의 견인 훅에 대하여 후상방으로 견인력을 가할 경우 발생하는 함입력으로 인하여 전치부 설측 경사가 더 감소되지는 않았다. 견인 훅의 높이가 5 mm인 경우 후상방 견인력을 가하면, 측절치의 치관 순측 및 치근 설측 이동이 일어나고, 견치의 비조절성 후방 경사 이동이 심화되었다. 4 mm의 보상 만곡은 측절치의 치관 순측 및 치근 설측 이동을 일으키고, 견치의 비조절성 후방 경사 이동을 감소시켰다. 또한 전치부가 설측 경사된 모델을 기준모델과 같은 실험 조건으로 시뮬레이션 한 경우 치근면의 응력 분포와 25000배 확대된 그래프 상에서의 치아 이동 양상은 매우 유사하였다. 이상의 결과는 미니 임플랜트-SWA sliding 생역학을 구사 시 견인 훅의 위치와 와이어 상의 보상 만곡의 유무에 의해 전치부의 치축 조절이 달라지며 실제 임상에서 가이드라인으로 활용될 수 있을 것이다. Objective: With development of the skeletal anchorage system, orthodontic mini-implant (OMI) assisted en masse sliding retraction has become part of general orthodontic treatment. But compared to the emphasis on successful anchorage preparation, the control of anterior teeth axis has not been emphasized enough. Methods: A 3-D finite element Base model of maxillary dental arch and a Lingual tipping model with lingually inclined anterior teeth were constructed. To evaluate factors influencing the axis of anterior teeth when OMI was used as anchorage, models were simulated with 2 mm or 5 mm retraction hooks and/or by the addition of 4 mm of compensating curve (CC) on the main archwire. The stress distribution on the roots and a 25000 times enlarged axis graph were evaluated. Results: Intrusive component of retraction force directed postero-superiorly from the 2 mm height hook did not reduce the lingual tipping of anterior teeth. When hook height was increased to 5 mm, lateral incisor showed crown-labial and root-lingual torque and uncontrolled tipping of the canine was increased. 4 mm of CC added to the main archwire also induced crown-labial and root-lingual torque of the lateral incisor but uncontrolled tipping of the canine was decreased. Lingual tipping model showed very similar results compared with the Base model. Conclusion: The results of this study showed that height of the hook and compensating curve on the main archwire can influence the axis of anterior teeth. These data can be used as guidelines for clinical application.

데이터마이닝을 이용한 의료의 질 측정지표 분석 및 의사결정지원시스템 개발

김혜숙,채영문,탁관철,박현주,호승희 한국의료QA학회 2001 한국의료질향상학회지 Vol.8 No.2

Background : This study presented an analysis of healthcare quality indicators using data mining and a development of decision support system for quality improvement. Method : Specifically, important factors influencing the key quality indicators were identified using a decision tree method for data mining based on 8,405 patients who discharged from a medical center during the period between December 1, 2000 and January 31, 2001. In addition, a decision support system was developed to analyze and monitor trends of these quality indicators using a Visual Basic 6.0. Guidelines and tutorial for quality improvement activities were also included in the system. Result : Among 12 selected quality indicators, decision tree analysis was performed for 3 indicators ; unscheduled readmission due to the same or related condition, unscheduled return to intensive care unit, and inpatient mortality which have a volume bigger than 100 cases during the period. The optimum range of target group in healthcare quality indicators were identified from the gain chart. Important influencing factors for these 3 indicators were: diagnosis, attribute of the disease, and age of the patient in unscheduled returns to ICU group ; and length of stay, diagnosis, and belonging department in inpatient mortality group. Conclusion : We developed a decision support system through analysis of healthcare quality indicators and data mining technique which can be effectively implemented for utilization review and quality management in a healthcare organization. In the future, further number of quality indicators should be developed to effectively support a hospital-wide Continuous Quality Improvement activity. Through these endevours, a decision support system can be developed and the newly developed decision support system should be well integrated with the hospital Order Communication System to support concurrent review, utilization review, quality and risk management.

OCT 플라스미드를 갖는 원유 분해세균에 의한 Octane 분해능

최순영,김창숙,이명혜,황문옥,민경희 숙명여자대학교 자연과학연구소 1991 자연과학논문집 Vol.- No.2

원유 분해세균에 의한 원유 분해능을 조사한 결과, Xanthomonas campestris M12. Xanthomonas sp. M28, Acinetobacter lwoffi G1, and Klebsiella pneumoniae L25, 그리고 Pseudomonas maltophilia N246 등의 순서로 나타났다. Xanthomonas campestris M12, Xanthomonas sp. M28, 그리고 Pseudomonas maltophilia N246 균주 모두 octane 분해시의 온도는 30℃에서 최적이었으며, 최적 pH는 X. campestris M12와 Xanthomonas sp. M28이 7.0∼7.5이었고, P. maltophilia N246이 7.5∼9.0이었다. N246 균주의 최적 NaCl 농도는 3.0∼3.5%이었다. P. maltophilia N246와 X. campestris M12는 모두 플라스미드를 갖고 있음을 확인하였고, N246 균주로부터 플라스미드를 제거하였을 경우 octane 분해능이 소실되었으므로 이 플라스미드 위에 octane 분해 유전자가 있음이 확인되었다. 이 균주의 OCT 플라스미드의 크기는 118kb이었다. 또한, N246 균주는 ampicillin 항생제에 내성을 나타내었다. Xanthomonas campestris M12. Xanthomonas sp. M28. Acinetobacter lwoffi G1, and Klebsiella pneumoniae L25, Pseudomonas maltophilia N246 were screened to increase the ability for crude oil utilization. All of these could utilize hexadecane and octane with the exception of N 246 strain for only octane biodegradation. Thus N246, M12, and M28, strains were specially examined for octane oxidation. Octane biodegradation by three strains showed the optimal conditions at 30C, pH7.0∼9.0 and 0.2∼0.3% octane concentration as a substrate. It was found that P. maltophila N246 and X. campestris M12 had plasmid and the cured plasmid from N246 strain lost octane utilization. Therefore, it was confirmed that certain genes for octane utilization were located on OCT plasmid in N246 strain. The size of OCT plasmid in N246 strain was 118 kb. The N246 strain was resistant to ampicillin.

Dibucaine-금속 요오드 착물을 이온교환체로서 이용한 Dibucaine의 정량

최현영,이지연,허문회,안문규 慶星大學校 1998 論文集 Vol.19 No.1

Dibucaine-selective poly(vinyl chloride) menbrance electrodes were designed based on ion-association complex between dibucaine and metal iodide complex such as H??, Bil?? and CdI??. Stable potentiometric response was obtained with Meyer reagent at pH 3.0-5.5, with Dragendorff reagent at pH 3.0-5.0 and with Marume reagent at pH 3.0-5.5. The best plasticizer was 49 w/w% acetyl-tri-n-butly critrate for Meyer reagent, 65.3 w.w% for Marume reagent. The electrodes exhibited a linear response based on Meyer, Dragendorff and Marume complex were the concentration range of 2×10?4×10?M ,2×10×4×10?M, 2×10?1×10?M,respectively. The potentiometric response slope of optimized membrane electrodes based on Meyer, Dragendorff and Marume complex for dibucaine were 56.12,57.81 and 56.45?? with relative standard deviation of 2.75, 2.29 and 1.96%, respectively. This ISE methods are found to be sensitive, rapid, fairly accurate and are able to be empolyed successfully for the determination of dibucaine preparations.

소프트웨어 컴퍼넌트 재구축을 위한 개념 인식 및 정제

현창문,한은주,남혜영,김행곤 대구효성가톨릭대학교 응용과학연구소 1995 응용과학연구논문집 Vol.4 No.-

Most of present-day information system have been in use for a long time. They have been developed using the system development methods, programming tools data base hand-less. Even if the systems are adapted to chagned requirements from the surrounding world, the basic structure and the original technical and methodological ties have been retained. Our goal is to show how an object-oriented development method can be used to grandu-ally moderning an old system. We do this by showing how object-orientd reengineering method solve the software maintainability.