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      • 자궁경부 소세포암 4예의 임상적 특징과 예후에 관한 연구

        오영림,김흥열,어완규,김홍배 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        Background : To investigate clinicopathologic finding of patients with small cell carcinoma of uterine cervix, and to evaluate the recurrence pattern and survival time of small cell carcinoma of uterine cervix Methods : The medical records of four patients who were diagnosed with small cell carcinoma of the uterine cervix and whose initial treatment was between January 1990 and December 2006 were studied retrospectively Results : Patient ages ranged between 43 and 50 years. The clinical stages at diagnosis were Ib, IIa, IIb, IIIa. All patients presented with abnormal vaginal bleeding. Tumor size at diagnosis was under 2cm in 1 patient and over 2cm in 3 patients. Disease recurred in 3 patients at 5~26 months and all of them died. Through analyzing overall survival time, FIGO stage and tumor size were significant prognostic factors in small cell carcinoma of the uterus Conclusion : Small cell carcinoma of uterine cervix revealed poor prognosis. Our study found FIGO stage and tumor size were significant prognostic factors in small cell carcinoma of the uterine cervix. Because of limitation of number of patients, further large scaled multicenter studies are needed.

      • 토양으로부터 항세균성 물질을 생산하는 Streptomyces sp. 의 분리

        오현정,정완석,김세재,김창진,고영환 제주대학교 생명과학연구소 1999 제주생명과학연구 Vol.2 No.-

        제주도의 토양에서 분리된 방선균 307주를 대상으로, paper disc법과 시험관 희석 배양법을 사용하여 항세균성 물질을 생산하는 균주를 선별하였다. 약 3.3%에 상당하는 분리주들이 Escherichia coli 8749, Staphylococcus aureus 6538 그리고 Pseudomonas solanacearum 10692에 대해 항균효과를 나타냈고, 그 중에서 가장 높은 항균활성을 나타내는 BL93 균주를 최종선별하여 동정하였다. BL93 균주의 배양학적, 형태학적, 생리학적, 생화학적 그리고 화학분류학적 특성을 기준으로 볼 때 Streptomyces violaceus와 유사하였기에, Streptomyces sp. BL93으로 명명하였다. 이 균주가 생산하는 항세균성 물질은 butanol보다도 물에 더 잘 녹는 극성화합물로 chloroform이나 ethylacetate에는 거의 용해되지 않았다. 100℃에서 30분간 가열 처리해도 활성의 소실이 거의 없었고, pH 3∼9범위에서 안정하였다. 분리균주 BL93은 aspartocin을 생산하는 Streptomyces violaceus와 유사함으로, BL93이 생산하는 항세균성 물질의 동정 및 aspartocin과의 비교 검토가 선행되어야 할 것이다. Three hundred and seven isolates of Actinomycetes were isolated and purified from soil samples in Cheju Is. to screen antibacterial compounds. About 3.3% of the isolates showed antibacterial activity, and one of them, BL93, showed relatively higher antibacterial activity against Escherichia coli 8749, Staphylococcus aureus 6538 and Pseudomonas solanacearum 10692 by both paper disc method and tube dilution incubation method. The isolate BL93 was similar to Streptomyces violaceus based upon its cultural, morphological, physiological, biochemical and chemotaxanomic characteristics. It was designated as Streptomyces sp. BL93. The antibacterial substance produced by the isolate BL93 had higher affinity for water than butanol and was insoluble in chloroform or ethylacetate. Most of its antibacterial activity was retained even after heating at 100℃ for 30min and was stable at pH ranges 3 to 9. As the isolate BL93 was tentatively identified to be Streptomyces violaceus, the antibacterial substance preferentially need to be identified and compared with aspartocin, an antimicrobial compound produced by Streptomyces violaceus.

      • 원자의 선택적 2광자 공명성 3광자 이온화 과정에 관한 밀도행렬의 수치해

        오완영,남백일,강석찬,김영순 명지대학교자연과학연구소 1991 자연과학논문집 Vol.9 No.-

        2광자 공명성 3광자 이온화 과정에서 밀도행렬의 시간에 대한 미적분방정식을 수치해 석적으로 계산하여 기저상태와 2광자 공명 여기상태의 전자밀도 행렬요소 σ??와 σ??,이온화율 P, 그리고 동위원소 선택율 S를 Li과 Sr원자들에 대하여 계산하였고, Rate Approximation에 기초한 준정상해의 결과와 비교하였다. 비교적 큰 동위원소이동 값을 갖는 ??Li와 ??Li의 경우 레이저의 세기가 매우 작은 영역과 큰 여역에서는 P와 s의 수치해의 계산결과와 준정상해법 계산결과는 비교적 잘 맞는 경향을 볼 수 있었으며, ??Sr와 ??Sr의 경우 즉, 동위원소 이동값이 700MH?에 불과한 경우 Li원자보다 민감하여 준정상해법의 결과는 제한적으로 적용됨을 볼 수 있었다. We present results of numerical calculations obtained through solving integro-differential equations for the electron density matrices ?? and?? and the ionization rate P in two-photon resonant three-photon ionization of Li and Sr, as well as the selectivity S for the isotope separation. We also compare our results with the predictions from quasi-stationary solutions based on the rate approximation. Our numerical results for P and S show that the quasi-stationary solutions are valid at very high and very low laser intensities when the isotope shift is large as in the case with 4s of ??Li and ??Li, and that the validity is rather limited in the cases with small isotope shift as in 5p? ?S of ??Sr and ??Sr.

      • 생쥐 정소 발달과정에 대한 미세구조적 연구

        안영모,오승한,이정환,김완종 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.2

        Differentiation and development of the mouse testis were studied by light and electron microscopes from the newborn up to the adult stage. The purpose of the present study was to investigate the morphological changes of developing germ cells in seminiferous tubule and Leydig cells in interstitial tissue during the developmental process of mouse testis. The results were as follows: the seminiferous tubule diameter began to increase from 1 day and was fully developed at the 30th day after birth, particularly, the seminiferous tubule diameter was rapidly increased between 15 days and 30 days of age. Germ cells of various stages were embedded in cytoplasm of the Sertoli cell. Leydig cell contained numerous mitochondria with tubular cristae and well developed smooth endoplasmic reticulum. Spermatogonia were located close to the basal layer. Spermatocytes were connected to each other by the intercellular bridge until the late spermatid stage. An acrosome located to the head apex and the microtubule arrangement of flagellum shown the typical "9+2" pattern. At the newborn stage, the Sertoli cell and germ cells started to be already differentiated. Spermatids and immature spermatozoa were appeared at 30 days of age, and thereafter, spermatogenesis occurred actively. In conclusion, the development of mouse testis was completed after 30 days of age at which the secondary sexual characteristics and the spermatogenesis began to occur. These results suggest that ultrastructural features of developing germ cells and Leydig cell were thought to have close interrelationship with their functional accomplishment.

      • 야구경기 볼카운트에 따른 안타발생빈도에 관한 연구

        이용완,오수일 江原大學校附設體育科學硏究所 1994 江原大學校附設體育科學硏究所論文集 Vol.- No.18

        This study was tried to be analyzed in the object of ninety five games, ninety eight schools had joined in three competitions in order to find out hits-made-percentage according to ball count in these high school baseball games. The conclusions to this analysis were as follows. 1. Hits-made-ratio (HMR) according to the ball count. HMR was the highest when the ball count was no ball, no strike (0-0) and as a whole hits were made within the third ball. But batting average was over 30% when ball count was advantageous for hitters. Each team in each game produced 7.99 hits on the average and hit more than one when ball count was no ball, no strike (0-0) and one ball, one strike (1-1). Thes was almost the same as HMR. Superior schools in the competitions were higher than non-superior schools in HMR and Batting Average. 2. HMR according to the base-runner or no base-runner HMR was high in case runner was on no base, but BA was high when runner was no bases. These were almost same between superior them and non-superior team, but superior teams were high in batting ability irrespective of runner. 3. HMR according to the ball count when there is base runner or not. HMR and BA was high irrespective of runner in third ball of pitcher. In HMR there is little difference batween superior team and non-superior team, but in BA superior team was high under the various ball counts. 4. HMR according to the pitched number. HMR according to the pitched number was produced within the third ball of pitcher. 5. HMR according to ball count was high in the first ball of pitcher. Especially when ball count was advantageous for hitter, percentage of slugging very frequent. This tells that slugging gives a great influence on winning the game. 6. Bases on balls, hit by pitched ball, sacrifice hits, batting obstruction, errors and strikeouts according to the ball count. Bases on balls was so high in 3-2 that hitters was patient, and hit by pitched ball, sacifice hits ans errors happened so often in 0-0 that discomfort of pitcher, bunt and discomfort of defence could be showed, in the first pitching. Stride-outs after two strikes is the reason why hitters was not flexible to the various changed balls.

      • KCI등재후보

        소형엔진의 배출가스측정방법에 따른 질소산화물 및 매연에 관한 연구

        한영출,나완용,오용석,문병철,박봉규,박귀열 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.3

        Recently, increasing usage of diesel vehicle, many countries try to reduce the pollutant materials by emission regulation standard. Particularly, in our country, the supplement ratio of diesel vehicle is high, and air pollution by vehicle exhaust gas is very serious. So, in study, we tested exhaust gas by various mode in light duty diesel engine. Therefore, we can know about NOx and smoke seriousness.

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