하악골 전돌자의 악교정 수술을 동반한 교정치료 전후 하악골 주위조직의 변화에 관한 연구

양병호,차경석 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.2

심한 골격성 전후방 및 수직적 악골 부조화를 동반하는 경우는 교정치료 만으로는 만족할 만한 결과를 얻기 어렵고 많은 전후방적인 이동과 치료의 안정성을 얻기 위하여 교정치료와 동반한 악교정수술이 필요하다. 하악전돌증 환자에서의 치료의 목적은 저작,발음 등 악구강계의 기능을 개선하고 안모의 심미성을 증진시키는 한편 안정성을 유지하는 데에 있다. 악교정수술에 의한 하악골의 이동으로 위치의 변화를 보이는 조직으로는 설골, 인두, 혀 등이 있다. 악교정수술을 동반한 교정치료를 받은 골격성 하악전돌증 환자에서 주위 조직들에서 변화 양상을 관찰하고 악교정수술 전후와 보정기간 후의 회귀나 재발에 의한 설골, 인두, 혀 및 상하순의 변화를 살펴보기 위하여 본 연구를 시행하였다. 본 연구에서는 하악전돌증을 주소로 내원하여 하악상행지 시상골절단술을 동반한 교정치료를 받은 환자 22명의 측모두부방사선 규격사진을 수술 전 (T1), 수술 후 (T2), 교정장치의 제거 2년 보정 후 (T3) 3회에 걸쳐 계측 및 비교한 후 다음과 같은 결과를 얻었다. 1.수술 후 설골이 상악골 및 교합평면에 대해 시계방향으로 회전하였으며 보정기간 후 회귀함을 보여주었다. 2.하악골의 수술에 의한 후방이동 후 설골이 후하방으로 이동하였으며 보정기간 후 상전 방으로 회귀함을 보여주었다. 3.인두의 깊이 변화는 상부에서 수술직후 약간 감소하는 경향을 보여 주었으나 보정 전후에 전반적으로 유의한 차이가 없는 것으로 나타났다. 4.혀의 기저부와 관련해서는 혀 기저부 각 (Cv4ia-hy-pt)이 감소하고, 혀의 기저부 배면이 후하방으로 변화하는 양상을 보여주었으며 보정기간 후에 상방으로 변화하였다. 5.상하순의 두께는 상순에서는 수술 후 감소하였다가 다시 증가하는 양상을, 하순이하의 연조직에서 두께가 증가하였다가 감소하는 형태로 나타났다. 이는 하순에서는 수술 후 잉여 연조직에 의한 두께의 증가가 나타나고 상순에서는 구륜근에 의한 장력에 의해 상순의 두께가 감소하였다가 보정 기간 후 새로운 악골 위치로 적응하는 것으로 생각된다. Severe skeletal anteroposterior and vertical discrepancy is difficult to obtain satisfactory result by only orthodontic treatment, and much anteroposterior movement and treatment stability require orthodontic treatment with orthognathic surgery. The treatment goal of mandibular prognathic patients is to promote the function of stomatognathic system including mastication and phonetics, to improve the esthetics of facial profile and to maintain stability. Positional changes of hyoid bone, pharynx and tongue were seen with mandibular movement after orthognathic surgery. This study was performed to observe the changes of perimandibular tissues of orthodontic patients with skeletal mandibular prognathism who treated with orthodontic treatment, and the changes of hyoid bone, pharynx and tongue by relapse or recurrance after before and after orthognathic surgery and retention. The 22 patients who had mandibular prognathism were selected. They treated with orthodontic treatment with sagittal split ramus osteotomy as orthognathic surgery. And lateral cephalometric radiographs were taken 3 times : pre-surgery (T1), immediate post-surgery (T2) and 2 years after retention (T3). The results were as follows : 1.The hyoid bone returned back after clockwise rotation to maxilla and occlusal plane during retention (p〈0.01). 2.The hyoid bone moved posterior-interiorly by mandibular surgery and returned back anterior-superior after retention. (p〈0.01) 3.The changes of pharyngeal depth showed a little decrease at upper area in post- surgery, but it was not a significant difference generally through before, after and retention. 4.In relating to tongue base, the angle of tongue base was decreased and the dorsal area of tongue base moved to inferior-posterior direction and to superior direction again after retention (p〈0.01). 5.Related to the thickness of upper and lower lip, the thickness of upper lip decreased after surgery, and the soft tissues below lower lip increased after surgery and decreased after retention.

복소함수 T_c(z)=z^n+c의 쥴리아 집합

양승갑,조경숙,조성훈 명지대학교 교육대학원 1998 敎育大學院 論叢 Vol.1 No.-

복소 함수의 쥴리아 집합이란 무한대로 발사하는 점들의 집합의 경계를 말한다. 이것은 쥴리아 집합의 어떤 점은 무한대로 발산하지 않는 궤도를 갖고 있으나, 이 궤도의 근방에서 무한대로 발산하는 궤도를 갖는 점이 존재함을 의미한다. 본 논문의 목적은 T_c(z)=z^n+c 형태의 복소 함수의 쥴리아 집합에 대한 연구에 있다. 이 때 z와 c는 복소수이고, n≥2이다. 특히, 매개 상수 c 에 대한 여러 가지 형태의 쥴리아 집합에 대하여 살펴보고, 또한 쥴리아 집합에 대한 주기성과 대칭성을 조사하였다.

Cone-beam CT를 이용한 제II급 부정교합 아동의 상기도 형태에 관한 3차원적 연구

홍지숙,김대성,오경민,김윤지,이규홍,박양호 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.3

Objective: The aim of this study was to evaluate the volumes and areas of the upper airways in children with Class II malocclusion, using three dimensional cone-beam computed tomography (CBCT) and to compare the volumetric and cross-sectional measurements and cephalometric variables to investigate possible relationships between the upper airway and facial morphology. Methods: CBCT scans were obtained from 37 subjects (17 boys and 20 girls; average age, 11.02 years). The upper airway volumes and areas were measured, and compared with cephalometric variables. Results: The area of the PNS-posterior plane (SPP) was significantly smaller in the Class II malocclusion group (p < 0.05). Also, the volumetric and cross-sectional measurements were lower in Class II than in Class I malocclusion groups, although the differences were not significant between the two groups (p > 0.05). The Class II malocclusion group showed significantly smaller values of PFH, mandibular body length, pog to N perp and showed larger values of FMA, ANB, and facial convexity than the Class I malocclusion group. The volume of the upper airway in front of PNS point (WN) showed negative correlation with ANB (p < 0.05). Conclusions: The Class II malocclusion group had a narrower upper airway associated with a decreased posterior facial height and a divergent growth pattern than the Class I malocclusion group. 성장기 아동의 상기도 협착은 두개안면 성장에 영향을 미칠 수 있다. 본 연구는 3차원 cone-beam computed tomography (CBCT)를 이용하여 제II급 부정교합 아동의 상기도 부피 및 단면적 계측치와 측모두부계측치를 비교하여 상기도와 안면 형태와의 연관성을 알아보고자 하였다. 37명의 아동(남자 17명, 여자 20명, 평균 연령 11.02세)의 CBCT를 촬영하였다. 연구 결과, 상기도의 PNS-posterior plane에서의 단면적(S_(PP))은 제II급 부정교합군에서 유의하게 작았다 (p < 0.05). 상기도 부피 계측치는 제II급 부정교합군에서 제I급 부정교합군보다 작았으나, 두 군 간 통계적으로 유의한 차이는 없었다. 제II급 부정교합군은 후안모고경(PFH), mandibular body length (p < 0.05), Pog to N perp (p < 0.01)에서 제I급 부정교합군보다 유의하게 작은 값을 보였고, FMA (p < 0.05), ANB, facial convexity (p < 0.01)는 유의하게 큰 값을 보였다. 제II급 부정교합군의 PNS 전방의 상기도 부피(W_(N))는 ANB difference 각도와 음의 상관관계를 보였다 (p < 0.05). 제II급 부정교합 아동은 상대적으로 좁은 상기도 부피를 가지며 이에 따른 감소된 후안모고경(PFH)과 하악골의 divergent한 안면 성장 양상을 보였다.

초음파 조사에 의한 트리암시놀론 아세토니드 겔의 피부투과

송경숙,김영일,양재헌 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.2

This study is to enhance drug penetration via skin and investigate anti-inflammation effect following adoption of ultrasound. For this goal gel containing triamcinolone was prepared and the skin penetration rate and the change effects of blood plasma ingredients and serum enzyme were investigated. Using Franz type diffusion cell and the skin of hairless mouse, the permeation enhancing effect of ultrasound was tested. After the injury by direct trauma, the blood test was performed by measuring WBC, lymphocyte, and neutrophyl, and by analyzing CPK and LDH. The ultrasound transducer whose technical specification is geometric area(GA) 1.4㎠, effective radiation area(ERA) 0.8㎠, and beam non-uniformity ratio(BNR) 6.0 max was used. The influence of frequency having an effect on skin permeation rate was higher in the case of using 1MHz and continuous treatment. The temperature of receptor phase was not influenced in skin permeation by phonophoresis. Skin permeation increase attended by intensity of ultrasound, the permeation of triamcinolone was accelerated at 2.5 w/㎠ than 1.0 w/㎠. Following muscle injury phonophoretic group the number of WBC, neutrophil and lympholyte were decreased significantly as compared with both control group and ultrasound group. The result of variation of serum CPK and LDH activity conformed to the phonophoretic effect as same pattern with the variation of WBC, neutrophil and lymphocyte.

세침 흡입 생검으로 진단된 간의 혈관근지방종 1 예

이경아,유은실,민영일,김해련,심기남,정훈용,양석균,홍원선,박의련,이문규 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6

Hepatic angiomyolipoma is a rare benign tumor of the liver composed of blood vessel, smooth muscle cells, fat and myelocomponent. The preoperative diagnosed of the lesion is important because of its therapeutic implications. Radiologic findings are not specific because the composed elements are variable in proportion and distribution. Thus, the findings at computed tomography, ultrasono graphy and magnetic resonance imaging may be only suggestive and its definitive diagnosed requires histologic confirmation. We experienced a case of hepatic angiomyolipoma in patient with chronic hepatitis diagnosed preoperatively by fine-needle aspiraton biopsy under ultrasound guidance. To our knowledge, this is the first case of hepatic angiomyolipoma diagnosed preoperatively in Korea. We report it with review of literatures.

RSS기반 블로그 에이전트를 사용한 교육용 블로그 구현

황의경,문양세,김혜숙,김진호,이상민 강원대학교 정보통신연구소 2007 정보통신논문지 Vol.11 No.-

More than 80% of the Internet users are familiar with blogs and exploit blogs as their primary communication tools in Korea. These blogs are widely used as a representative personal media service in educational applications as well as business marketing or information sharing applications. In this paper, we present an efficient mechanism of using blogs for educational applications. For this, we first investigate the major problems that the current educational blog sites have. We then propose a new notion of the blog agent that solves the problems and makes it easy to exploit blogs for educational applications. Contributions of the paper can be summarized as follows. First, we investigate the problems with respect to the homework management by analyzing the existing educational blog sites. Second, we present how we can solve the problems by using blog agent. Third, we show that, if exploiting the blog agent, we can easily design blog sites for homework, consultation, or lecture material management. Fourth, through a survey on current blog-related techniques, we select the RSS-based technique to implement our intelligent blog agent. Fifth, we implement the blog sites for homework, consultation, and lecture material management by using "Cyworld's Paper," which is one of RSS-based blog techniques.

대황황련해독탕의 항고지혈증 작용

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2001 No.-

Whangryunhaedok-Tang (WT) is formulated with Coptidis Rhizoma, Phellodendri Cortex, Scutellariae Radix and Gardeniae Fructus, and Daewhang-whangryunhaedok-Tang (DWT) is made by the combination of Rhei Rhizoma, a wellknown anticostipation drug in WT. Therefore, DWT has been evaluated for antihyperlipidemic effects on experimental hyperlipidemic rats and mice induced by corn oil and high cholesterol-diet. Oral administration of DWT significantly inhibited the increase of serum triglyceride and LDL-cholesterol levels, and the decrease of serum HDL-cholesterol levels in hyperlipidemic rats induced by corn oil. Also, oral administration of DWT significantly prevented the increase of serum total cholesterol, triglyceride and LDL-cholesterol, and liver total cholesterol and triglyceride in 1% cholesterol-diet fed mice. These results suggest that DWT is effective for the treatment of hyperlipidemia.

독시사이클린 나노입자가 함유된 치주용 키토산 스트럽의 제조 및 특성

송경숙,양재헌,김영일,정규호 한국약제학회 2001 Journal of Pharmaceutical Investigation Vol.31 No.4

Local drug delivery by using biocompatible polymers has been developed in the treatment of periodontitis for many years. In the field of dental therapy, doxycycline is usually a first choice because of its broad-spectrum antibiotic activity. The strip releases antibiotics for a week, and the polymer should be degradable after a week. In this study, we prepared and evaluated the chitosan strips and nanoparticle strips containing doxycycline hydrochloride, and studied their antiacterial activity, dissoultion, and degrability in vitro. The weight of cast strip containing a 5 mg of doxycycline hydrochloride and a 45 mg of chitosan polymer was 57.67±0.17 mg. The release rate of doxycycline hydrochloride from the strip was measured by HPLC. The drug released from chitosan strip and nanoparticle strip was shown to be 50 ㎍/ml, in first 24 hours. In antibacterial test showed growth inhibitory activity after 24 hrs anaerobic incubation. In vitro degradability showed demolished weight of 93.74±0.08% chitosan strip, 82.48±1.29% chitosan nanoparticle strip, 2.47±1.99% polycarprolactione strip (control). These results showed that, with this doxycycline hydrochloride strip, it is feasible to obtain a sustained release of the drug within the periodontal pocket for seven days which may be improve for local drug delivery system for treatment of periodontal disease.

대황황련해독탕의 사염화탄소 유발 간장해 보호효과 미치 급성독성

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-

ABSTRACT - This study was performed to evaluate hepatoprotective effect of daewhang-whangryunhaedok-Tang(DWT) on liver injured rats induced by CCI_4 and the acute oral toxicity of it in mice. The activities of serum transaminase(ALT/AST), alkaline phosphatase(ALP) and lactic dehydrogenase(LDH), the levels of serum total cholesterol(TC) and triglyceride(TG), change of liver enlargement, and inhibitory activities of lipid perotidation, catalase and glutathione-S-transfrease(GST) in liver microsome were determined in hepatotoxic rats induced by CCI_4. DWT was significantly reduced the serum ALT, AST, ALP, LDH. TC and TG lecels. And, the increase of lipid peroxidation, decrease of catalase and GST activities in the liver microsome of CCI_4-intoxicated rat were significantly improved by the treatment of DWT. Male and female mice were administered maximum dosages of 5.000 mg/kg b.w. of DWT. After single oral administration of DWT to mice, we observed them daily for 2 weeks.DWT did not induce any toxic signs in the mortalitie, clinical signs, body weight changes, and gross necropsy finfings of mice. Based in these results. It is concluded that DWT may have the hepatoprotective effect on CCI_4 induced hepatotoxicity in rats. Also. DWT may have no side effect and its LD_50 value may be over 5.000mg/kg b.w. in mice.

ACL 손상환자의 보행형태 분석

이경일,박양현,김용숙 朝鮮大學校 스포츠科學硏究所 2004 스포츠科學硏究 Vol.15 No.-

By analyzing on walking patterns of patients who have damaged ACL, we intended to use this study as data for several walking researches. Followings are the result of angles and angular velocities that are variables in the study. 1. The angle of ankle showed flection of 91.28˚ and 93.54˚ at the point E2 (opposite toe off) and at the point of E3(opposite heel contact). The angle of normal left foot was flection of 96.66˚ and 92.30˚ when it was at the point of E1(heel strike) and E2(opposite toe off). 2. The angle of knee showed the biggest curve of 121.07˚ at the point of E2(opposite toe off ) and there was a significant difference with the angle of left knee. 3. The angle of hip joint was the biggest numerical value extension, 49.93˚ at the point of E1(heel strike ) and at the point of E3(opposite heel contact), it showed the curve of 38.43˚. We could see the significant difference at normal left hip joint but at the point of E3(opposite heel contact) the numerical value of the curve appeared to be 89.49˚. 4. The angular velocity of ankle was the biggest as 67.33 at the point of E1(heel strike) and simultaneously, the angular velocity of left ankle appeared to be the smallest as -19.80˚. 5. The angular velocity of knee was -78.28 at the point of E2 (opposite toe off) and at the same point, the velocity of normal left knee was 46.68˚ which was the biggest numerical value. 6. The angular velocity of hip joint were -7.18˚ and -58.03˚ at the point of E1(heel strike) and E2(opposite toe off). At the same point, the velocity of left hip joint showed bigger number of 27.45˚ and -6.11˚.