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      • 혈액투석환자 배우자의 스트레스와 대응에 관한 연구

        원삼순,권혜진 중앙대학교 의과대학 의과학연구소 1992 中央醫大誌 Vol.17 No.4

        This descriptive study designed to identify stress factors and level and helpful coping methods of hemodialysis patient's spouse. Data were collected from 60 subjects who were spouses of hemodialysis patient of conveniently selected 4 Hemodialysis Units in the city of Seoul. The Collection of data it was carried out by the researcher from the 7th of Octobor to 20th of October, 1992. Two instruments were used to collect the data ; 1. Stress questionaire was developed by researcher which was combined review of literature and the result of interviewer, consisted 30 stress factor items and measured by five point Likert scale. The items were categorized physical, psychological and socioeconomic area. 2. Helpful coping questionaire developed by investigator through literature review and result of interviewer, included 50 items and measured by five point Likert scale. Helpful coping items were classified into two categories, the problem oriented and the affective oriented. Data was analyzed by S.A.S. computer porgram using percentile, means and standard deviation, t-test and Pearson correlation coefficient. The results of this study are summerized as follows 1. The spouses of hemodialysis patient were found to be stressful in general and the items with high stress were "To be treated indefinite period of time", "Uneasiness of trevel", "To be say with their spouse who suffer pain", "To ingest medication continuously", "Financial burden", "No treatment except kidney transplantation", "Anxious about disease transmission due to transfusion" and the highest stress category was physical. 2. The spouses of hemodialysis patient were shown to be helpful by the coping methods and the most helpful coping items "To accept as a fate" and "Self condolence comparing others who were in a more serious rather than thier sitution" and the higher helpful coping method was affective oriented. 3. The result of the analysis of the relationship between scores of stress categories and general characteristics was as follows : Spouse's sex, house shape, and occupational status before the patient got illness showed a statistically significant difference in score of stress categories(P<0.05) 4. The result of the analysis of the relationship of the relationship between helpful coping methods and general characteristics was as follows : The number of family, the state of medical insurrance, spouse's disease, the number of hemodialysis, and having or not having complication related with hemodialysis showed a statistically significant differance in helpful coping methods(P<0.05) 5. There was significant differance among stress categories and coping methods.(P<0.01)

      • 갑상선기능저하증 이환견에 대한 치료 증례

        김혜원,이선희,임수정,박형진,김태신,송은식,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

        A 10-year-old, male, poodle dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University because of continuous cough and cardiomegaly. Weight gain, lethargy, unwillingness to exercise and decreased activity was revealed on history. Obesty and alopecia was also observed on physical examination. Hypercholesterolemia and increased ALP was revealed on blood exam. So, evaluation of thyroid gland function was performed and cTSH concentration was increased. tT4 and fT4 concentrations was decreased. Results of a history, physical examination, blood exam, and thyroid gland fuction test support a diagnosis of hypothyroidism. Initial therapy with sodium levothyroxine was indicated. On 32 days after treatment of hypothyroidism, clinical signs was relieved and cTSH concentration was decreased, tT4 and fT4 concenctrations was increased.

      • 벼 엽록체 small HSP의 과발현에 의한 형질전환 식물체의 내열성 증가

        원성혜,조진기,이병현 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

        To investigate the function of chloroplast small heat shock protein (HSP), transgenic tobacco plants (Nicotiana tabacum L, cv. SR-1) that constitutively overexpress the rice chloroplast small HSP (Oshsp26) were generated. Effects of constitutive expression of the Oshsp26 on thermotolerance were investigated with the chlorophyll fluorescence. After 5-min incubation of leaf discs at high temperatures, an increase in the Fo level, indication of separation of LHCII from PSII, was mitigated by constitutive expression of the chloroplast small HSP. When tobacco plantlets grown in Petri dishes were incubated at 52℃ for 45 min and subsequently incubated at 25℃, leaf color of wild-type plant became gradually white and all plantlets were finally died. Under the conditions in which all the wild-type plants died, more than 80% of the transformants remained green and survived. It was also found that the levels of Oshsp26 protein accumulated in transgenic plants were correlated with the degree of thermotolerance. These results suggest that the chloroplast small HSP plays an important role in protecting photosynthetic machinery, as a results, increases thermotolerance of whole plant during heat stress.

      • KCI등재후보

        컴포머 충전과정에 따른 상아질 투과도의 변화

        조혜진,이경하,이세준,이광원 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

        Compomer is composed of matrix and filler; matrix is made of the combination of resins and polycarboxylic molecules that are light-cured. and a filler is a glass component which is capable of ion-release. The resin content of compomers produces polymerization shrinkage which can adversely affect marginal adaptation. Pretreatment is a fundamental step which is treated with conditioner or primer in the use of these materials. Microleakage of restorative materials has been investigated mostly by dye penetration method. Dye penetration method was not quantitative and not measured repeatedly. Fluid filtration method. introduced and developed by Pashley's group, has been extensively used for 20 years for research purpose to understand the physiology of dentin, as well as the effects of various restorative treatments on dentin permeability. It permits quantitative, nondestructive measurment of microleakage in a longitudinal manner. The purpose of this study was to evaluate the change the change of dentin permeability according to the process of compomer restoration. In this study, CI Ⅴ cavities were prepared on buccal surface of thirty extracted human molars. The prepared cavities were etched by 37% phosphoric acid. The experimental teeth were randomly divided into three groups. Each group was treated with following materials; Group 1 : Prime & Bond NT/Dyract AP, Group 2: Single Bond/F2000 compomer, Group 3 : Syntac Single Component/Compoglass. The bonding agent and compomer were applied for each group following manufactures information. Dentin permeability of each group was measured at each process by fluid filtration method; Step 1 : preparation(smear layer), Step 2 : etching(smear layer removal), Step 3 : applying the bonding agent, Step 4 : filling the compomer. Dentin permeability was expressed by hydraulic conductance(㎕ min^-1cmH_2O^-1). The data were analysed statistically using One-way ANOVA and Sheffe's method. The results were as follows : 1. Dentin permeability differences between each process were significant except between step 1 and step 2(p<0.01). 2. Dentin permeability after removal of smear layer was highly increased(p<0.01). 3. In most case, decrease of dentin permeability was obtained by applying bonding agent(p<0.01). 4. Dentin permeability differences among the experimental groups were not significant(p>0.05). 5. None of compomers used in this study showed perfect seal at the interface.

      • 낙동강 하구의 환경요인과 미생물의 상호관계에 관한 연구

        김원진,이혜주 동아대학교 환경문제연구소 1998 硏究報告 Vol.21 No.2

        The influences of estuary barrage on the changes of physiocochemical environmental factors and distribution of microorganisms were investigated 23 times from Sep. 1997 to Aug. 1998 at three sites of Naktong river estuary. Inorganic nutrients were higher in Site I (freshwater, upper side of estuary barrage) rather than in Site Ⅱ and Ⅲ(seawater, under side of estuary barrage). The spatial distribution of three inorganic nitrogen compounds at Site Ⅰwas high because of domestic sewage and agricultural water, and the seasonal distribution was high in winter. This may be due to the expended residence time of water in estuary by the construction of the barrage. The distribution of microorganism was also higher in Site I than in other sites spatially. There were significant correlations between environmental factors and distribution of bacteria according to multiple correlation analysis. Especially, bacteria were positively correlated with concentration of inorganic nutrients and precipitation. Factor analysis with 16 parameters led to extraction of 4 factors that accounted for 58% of the ecosystem variation of Naktong River Estuary. The factors were identified in the following order ; 1) the effect of Naktong river estuary barrage, 2) phytoplankton, 3) characteristics of season, especially summertime, 4 input of soil and fecal contamination.

      • KCI등재

        주의산만을 주소로 소아정신과를 내원한 아동의 인지적 특성 : T.O.V.A. 양상을 중심으로

        신의진,이수진,이혜란,고려원 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.2

        본 연구에서는 주의산만을 주소로 내원하는 아동을 진단 준거에 따라 분류하고 각 진단 집단을 설명할 수 있는 인지적 특성을 T.O.V.A. 양상을 중심으로 설명하였다. 소아정신과를 방문한 65명의 아동을 각각 주의력결핍 과잉행동장애(38명), 틱장애(17명), 그리고 기타 정서장애(10명) 집단으로 분류한 후 주의산만의 정도에 영향을 미칠 수 있는 집단의 연령 및 지능(전체 지능, 동작성 지능, 언어성 지능)을 먼저 파악한 후 T.O.V.A.의 중다구인(누락오류, 오경보오류, 정반응시간, 반응시간 표준편차, 예기반응, 다중반응)을 통해 주의산만의 양상을 살펴보았다. 세 집단 간에 연령에서 집단 간에 유의미한 차이가 나타나 연령 수준의 차이에서 기인한 효과를 배제한 결과, 언어성 지능에서 세 집단 간에 유의미한 차이가 나타났다. 또한, T.O.V.A.의 정반응 시간(전반부, 후반부, 전체)에서 세 집단간에 유의미한 차이가 있는 것으로 나타났다. 주의력결핍 과잉행동장애 집단은 틱장애 및 기타 정서장애 집단보다 T.O.V.A.의 정반응 시간이 길어 정보처리의 지연을 시사해 주었다. 한편 주의산만을 주소로 내원하는 아동의 경우 T.O.V.A. 양상과 더불어 연령과 지능의 효과에 대해 신중히 고려해야 할 필요가 있겠다. 중심 단어 : 인지적 특성ㆍ주의산만ㆍT.O.V.A.ㆍ정반응시간ㆍ주의력결핍 과잉행동장애ㆍ틱장애ㆍ기타 정서장애. Objective : This study aims to investigate the cognitive characteristics of clinically referred children with symptoms of inattention, cash as having ADHD, tic disorder, and emotional disorder. Methods : 65 boys(38 with ADHD, 17 with Tic disorder, and 10 with Emotional disorder) were individually assessed using the KEDI-WISC(FIQ, VIQ, PIQ) and T.O.V.A.(errors of omission, errors of commission, reaction time, variability, anticipatory response, multiple response), and the results of those tests were analyzed. Results : There was significant difference among three diagnostic groups of the VIQ of KEDI-WISC and the reaction time of T.O.V.A. after the correction of the effect of age difference. Conclusion : The finding suggest that the reaction time of T.O.V.A. might be the useful variable to differentiate the ADHD from other psychiatric disorders and the effect of age and IQ difference should be considered carefully to diagnose in clinical setting. KEY WORDS : Cognitive characteristicㆍInattentionㆍT.O.V.A.ㆍReaction time.

      • 대학생의 성별, 학년별, 전공별 스트레스에 관한 연구

        김보혜,안윤정,정민영,차지영,최경원,김지현,김수지,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

        The purpose of this study was to investigate the level and effect of stress on physical and mental health. Based on that result, we offer the basic research to lessen students' stress and make a program to promote health condition effectively. Subjects were 526 university students. (male: 232(44.1%) female: 294(55.9%). composed of 7 majors: human studies&social science, management, Science&technology, education. law, medicine, entertainment. freshman 108(20.5%), sophomore 140(26.6%) junior 148(28.1%), senior 130(24.7%)) Subjects were filled with 127 questionnaires. T test and ANOVA were used to evaluate each stress levels. The .05 level of significance was the critical for this research. Also used the correlation to know the relation between stress levels and effects. The result of the study were as follows: 1. According to gender, male students got 2.37, female students got 2.46 on the stress level(p=.05). And also the belonging items showed female students got higher stresses than male students. 2. According to grade, the average score of stress level was 2.42. sophomores got the highest stress and freshmen got the lowest stress level. But that was not meaningful difference. freshman and sophomore got higher stress on studying. and except the freshman, all grades got severe stress on employment. 3. According to major, there were differences on university life and surroundings. On university life, the students who majored management got highest stress and the students who majored Education got the least stress. And on surroundings, the students who majored Law got highest stress. 4. According to gender, female students suffered from more stress effects than male students.(male 2.3725 female 2.4657 t:-1.968 p:.050) 5. According to grade, the average score of stress was 2.2285. sophomore got 2.3042 and junior got 2.2148 on stress effects. 6. According to major, The students who major in law got more stress effects caused by family than any other students. The students who major in entertainment and gymnastics got more stress effects than any other students in surroundings. 7. There were significant correlations between the stress level and effects(r.=847, p=.000).

      • KCI등재

        8.3% Carbamide Peroxide 함유 펜 형 자가미백제인 BIancTis Forte의 색조개선 및 안전성에 관한 임상연구

        이진경,민선홍,홍성태,오소람,정신혜,황영혜,유성엽,배광식,백승호,이우철,손원준,금기연 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.2

        This clinical study evaluated the whitening effect and safety of polymer based-pen type BlancTis Forte(NIBEC) containing 8.3% carbamide peroxide. Twenty volunteers used the BlancTis Forte whitening agent for 2 hours twice a day for 4 weeks As a control. Whitening Effect Pen (LG) containing 3% hydrogen peroxide was used by 20 volunteers using the same protocol. The change in shade (ΔE^(*) color difference) was measured using Shadepilot™ (DeguDent) before, during and after bleaching (2 weeks, 4 weeks and postbleaching 4 weeks). A clinical examination for any side effects (tooth hypersensitivity or soft tissue complications) was also performed at each check-up. The following results were obtained. 1 Both the experimental and control groups displayed a noticeable change in shade (ΔE) of over 2 No significant differences were found between the two group (p>0.05) implying that the two agents have a similar whitening effect. 2 The whitening effect was mainly due to changes in a and b values rather than in L value (brightness). The experimental group showed a significantly higher change in b value thus yellow shade than the control(p < 0.05) 3 None of the participants complained of tooth hypersensitivity or soft tissue complications confirming the safety of both whitening agents 8.3%의 carbamide peroxide를 함유한 펜형 코팅용 미백제인 BlancTis Forte (NIBEC, Seosul & JinCheon)를 실험군으로, 3% hydrogen peroxide를 함유한글 Whitening Effect Pen (LG. Seoul) 제재를 대조군으로 각각 피험자 20명에게 2시간씩 1일 2회 제조사의 지시대로 치아표면에 4주간 적용하도록 지시하고 색조개선 효능과 안전성을 평가하였다. 미백 효과는 미백 전 및 미백 2주, 4주 및 미백 종료 4주 후에 Shadopilot™을 이용하여 색 변화를 측정하였고, 매 내원시기마다 모든 환자는 치수생활력 검사와 치주 및 치태 검사를 통해 부작용 여부 (치아과민증 및 구감 내 연조직의 부작용)를 기록한 후 다음과 같은 결과를 얻었다. 1.실험군 및 대조군의 색 변화량 (ΔE)은 2이상으로 인지할 수 있는 색 변화를 보였으며, 두 제품 간에는 통계적으로 유의한 차이를 보이지 않아 (p > 0.05) 유사한 미백효능을 나타냄을 알 수 있었다. 2,미백효과는 명도의 개선보다는 주로 a. b값의 변화에 의한 것으로 특히 실험군에서 b값의 변화, 즉 황색조의 개선효과가 대조군에 비해 유의성 있게 높은 것으로 나타났다 (p <0.05). 3.치아나 치은의 과민증이나 이상증상을 호소하는 피험자는 없어 두 제품 모두 안전성을 확인할 수 있었다.

      • KCI등재

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