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이세준,김득영 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.47 No.3
The optical properties of multilayered porous-Si formed by using electrochemical anodization with a current pulse modulation method were investigated. The photoluminescence intensity was observed to increase dramatically and to be slightly blue-shifted with increasing the period of the porous multilayer. The improvement in the photoluminescence property for multi-stacked porous-Si layers might be attributed to an enhancement of the overall size-effect resulting from the insertion of an interlayer with a high porosity between sandwiched layers with low porosity because these multi-stacked porous-Si layers might provide many luminescence centers in the vertical direction as well as the lateral direction. From the photoluminescence and optical ransmittance results for thermally treated porous-Si multilayers, the luminescence from multilayered porous Si is thought to originate from nanocrystallites structured with Si-H and SiH2 rather than from interface traps between porous-Si and SiOx.
이세준,김득영 한국물리학회 2007 Current Applied Physics Vol.7 No.2
The correlation of electrical properties with magnetic properties for the (Ga1xMn x)As epilayer was investigated. For electrical trans-port measurements, it was clearly observed that the electrical mobility is increased with decreasing temperatures for both the (Ga0.974-Mn 0.026)As/LT-GaAs epilayer and the LT-GaAs:Be epilayer. However, a dierent behavior was observed at the cryogenic temperatureregion. The electrical mobility of (Ga0.974Mn 0.026)As/LT-GaAs epilayer increases with decreasing temperature, while the mobility of LT-0.974Mn 0.026)As/LT-GaAsepilayer, the critical point is observed at 69 K, and this value is almost the same as theTC. This result indicates that the carrier transportin ferromagnetic (Ga1. xMn x)As epilayers might be related to a spin-ordering eect because the spins will be arranged with the samedirection below theTCdrop below theTC in the temperature-dependent resistivity curve is expected to be a result of the spin-ordering eect in the ferromagnetic(Ga0.974Mn 0.026)As/LT-GaAs epilayer.
이세준,백용한,이동기,이관식,이상인 연세대학교의과대학 2005 Yonsei medical journal Vol.46 No.1
Esophageal leiomyoma derived from the muscularis mucosae (MM) is a rare condition, and the optimal modality for diagnosis and treatment is controversial. Endoscopic ultrasonography can provide an accurate image of esophageal layer structure, providing information on lesion suitability for potential endoscopic therapy. We attempted to investigate the diagnostic value of a transendoscopic balloon-tipped miniature ultrasonic endoprobe for small esophageal leiomyomas derived from MM. We resected 7 small esophageal leiomyomas derived from MM by endoscopic mucosal resection (EMR), all of which were diagnosed by a balloon-tipped endoprobe. The endosonographic and pathologic features of 7 cases of small esophageal leiomyomas derived from MM were compared. The balloon-tipped endoprobe clearly showed all 7 small esophageal leiomyomas derived from MM, even those under 5mm in size (smallest lesion, 3.0mm). The endosonographic characteristics of small esophageal leiomyomas derived from MM were a hypoechoic mass with smooth, regular, and a well-defined outer margin and homogenous inner echogram arising from the second hypoechoic layer. Complete resections were possible in all 7 cases by EMR without any complications. Tumor size was 3.0-13.5mm (mean 7.8mm) in maximum diameter. In all cases, endosonographic findings by endoprobe were exactly concordant with pathologic finding in determining the tumors depth in the esophageal wall, tissue origin and characteristics, growth pattern, and size. We detail the balloon-tipped endoprobe is a simple, convenient, and very useful in making accurate diagnosis of small esophageal leiomyomas derived from the MM and the appropriate applications of EMR.
이세준,김똘미,정준표,이정일,박영년,김정환,문병수,이관식,이상인,박인서 대한소화기내시경학회 2002 Clinical Endoscopy Vol.24 No.2
Malignant melanoma is one of the most common malignancies associated with metastatic disease to the gastrointestinal tract. Malignant melanotic melanomas metastasized to the stomach and duodenum, stomach, small bowel, and rectum have been reported in Korea. However, amelanotic malignant melanoma metastasized to the gastrointestinal tract, to our knowledge, has not been reported in Korea. Recently, we experienced a case of amelanotic malignant melanoma metastasized to the duodenum in a 48 year-old man. The primary site was presumed to be the soft tissue near the right knee. Pulmonary and pancreatic metastasis were also noted at presentation. Despite systemic chemotherapy, the patient died of progressive disease at about 13 months after presentation. (Korean J Gastrointest Endosc 2002;24:104-107) 흑색종은 소화관으로의 전이가 흔한 악성 종양 중의 하나이다. 악성 흑색종 환자의 약 1~4%는 생전에 임상적으로 명백한 소화관 침범이 있으며, 부검에서는 약 60% 환자에서 소화관 침범이 있다. 악성 흑색종은 색소성과 무색소성으로 나눌 수 있는데, 이 중 무색소성 악성 흑색종은 전체 악성 흑색종의 2~8%를 차지하며 다른 악성 흑색종은 색소 침착의 변화가 있지만 무색소성 흑색종은 이러한 색깔 변화가 없는 것이 특징이다. 국내에서는 위, 십이지장, 소장 및 직장 등의 전이성 악성 흑색종이 보고된 바 있는데 모두 색소성 악성 흑색종이었으며, 아직 무색소성 악성 흑색종의 소화관 전이에 대한 보고는 없다. 저자 등은 최근 48세 남자 환자에서 십이지장으로 전이된 무색소성 악성 흑색종을 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
이세준,박효진,장진혁,Jeffrey L Conklin 연세대학교의과대학 2006 Yonsei medical journal Vol.47 No.2
Lipopolysaccharide (LPS), given in vivo, modulates opossum esophageal motor functions by inducing the inducible nitric oxide synthase (iNOS), which increases nitric oxide (NO) production. Superoxide, a NO scavenger, is generated during this endotoxemia. Superoxide is cleared by superoxide dismutase (SOD) and catalase (CAT) to protect the physiological function of NO. This study examined whether lower esophageal sphincter (LES) motility, NO release, and iNOS and nitrotyrosine accumulation in the LES are affected by LPS in vitro. Muscle strips from the opossum LES were placed in tissue baths containing oxygenated Krebs buffer. NO release was measured with a chemiluminescence NOx analyzer, and Western blots were performed to analyze iNOS and nitrotyrosine production. The percent change in resting LES tone after a 6-hour exposure to LPS was significantly increased compared to pretreatment values. The percent LES relaxation upon electrical stimulation was significantly decreased in the control group at 6 hours, indicating that the LPS treatment had an effect. The NO concentration in the tissue bath of LPS- treated muscle without nerve stimulation was significantly less than that of LPS treatment combined with SOD/CAT or SOD/CAT alone. iNOS and nitrotyrosine were detectable and increased over time in the LES muscle of both the control and LPS-treated groups. Antioxidant enzymes may play a role in regulating NO-mediated neuromuscular functions in the LES.