Solar urticaria in Korean patients

( Sung Min Kim ),( Young Ah Cho ),( Ji Su Lee ),( Ji Youn Hong ),( Jin Hee Kim ),( Joo Ran Hong ),( Hye In Cheon ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Solar urticaria (SU) is an uncommon type of photodermatoses characterized by erythematous wheal with pruritus after sunlight exposure, which shows a female predominance. Only a few studies to analyze the clinical features of SU were reported in Asia. Objectives: We aimed to analyze the clinical and photobiological characteristics of SU in Korea. Methods: We retrospectively investigated the medical records of patients with SU who visited the department of dermatology, Konkuk university medical center from January 2005 to January 2020. Results: Of a total of 44 patients, 36 (81.8%) were male and 8 (18.2%) were female. The mean age at onset was 17.6 years (range, 5-47) and the mean threshold time was 19.7 minutes. Among 32 patients who underwent phototesting, the action spectrum most commonly implicated was ultraviolet (UV) A only in 12 (37.5%), and then visible light (415nm) only was responsible for SU in 8 (25.0%). Three patients (9.4%) were induced by both UVA and visible light (415nm). Even 4 patients (12.5%) were triggered by only natural sunlight. Serum immunoglobulin E levels were measured in 33 patients, and 17 (51.5%) showed values higher than normal. The treatment most widely used were oral antihistamine (43.2%), followed by phototherapy (13.6%). Conclusion: SU is a rare photodermatosis in Korea, which shows a male preponderance. In this study, UVA and visible light (415nm) were predominant action spectrum of SU.

족궐음간경(足厥陰肝經) 오수혈 주치(主治)의 특성(特性)과 시동병(是動病)의 연관성(聯關性)에 관한 연구(硏究) -<침구갑을경(鍼灸甲乙經)>을 중심(中心)으로-

성수민,이성수,오세형,황민섭,윤종화,Sung, Su-Min,Lee, Seong-Su,Oh, Se-Hyoung,Hwang, Min-Sub,Yoon, Jong-Hwa 대한침구의학회 2006 대한침구의학회지 Vol.23 No.3

Objectives : It is known that the five Su points are very useful clinically. The following study was undertaken in order to find out the general characteristic and the origin of the five Su points. Methods: We investigated the relation of symptoms that are treated by five Su points and Shi-Dong Suo-Sheng-Bing(是動 所生病). The main reference book was Zhen Jiu Jia Yi jing(鍼灸甲乙經) and the author took Liver Meridian of Foot Gworeum(足厥陰肝經) as an example. Results : 1. Five Su point of Liver Meridian of Foot Gworeum(足厥陰肝經) treats Shi-Dong-Bing(是動病) of Liver Meridian of Foot Gworeum. It is peculiarity of Five Su point of Liver Meridian of Foot Gworeum, differed from the others acupoints. Symptoms of Shi-Dang-Bing appears with the abnormal pulsation of Merdian Gi(脈氣), and the special feature of Shi-Dang-Bing is the symptoms are consisted of disorders of whole body, trobles of an internal organ, and psychosomatic disorders. 2. In <Su Wen San Bu Jiu Hou Lun (素問 三部九候論)>, it is described the part of pulse feeling for Shi-Dong-Bing(是動病) of Liver Meridian of Foot Gworeum(足厥陰肝經) as ‘A region that is 2 Chon(寸) from the basic digital joint of the first toe’. This region is agree with the acupoint of Liver Meridian of Foot Gworeum in <Mai-Jing(脈經)>, <Qian-Jin-Yao-Fang(千金要方)>. And Haeng-gan(行間) Tae-chung(太衝), members of five Su-points of Liver Meridian of Foot Gworeum is situated the same region. So we suppose that the part of pulse feeling for Shi-Dong-Bing of Liver Meridian of Foot Gworeum is transformed into Haeng-gan(行間) Tae-chung(太衝), among the five Su points.

족궐음간경(足厥陰肝經) 오수혈 주치(主治)의 특성(特性)과 시동병(是動病)의 연관성(聯關性)에 관한 연구(硏究) -<침구갑을경(鍼灸甲乙經)>을 중심(中心)으로-

성수민,이성수,오세형,황민섭,윤종화,Sung, Su-Min,Lee, Seong-Su,Oh, Se-Hyoung,Hwang, Min-Sub,Yoon, Jong-Hwa 대한침구의학회 2006 대한침구의학회지 Vol.31 No.3

Objectives : It is known that the five Su points are very useful clinically. The following study was undertaken in order to find out the general characteristic and the origin of the five Su points. Methods: We investigated the relation of symptoms that are treated by five Su points and Shi-Dong Suo-Sheng-Bing(是動 所生病). The main reference book was Zhen Jiu Jia Yi jing(鍼灸甲乙經) and the author took Liver Meridian of Foot Gworeum(足厥陰肝經) as an example. Results : 1. Five Su point of Liver Meridian of Foot Gworeum(足厥陰肝經) treats Shi-Dong-Bing(是動病) of Liver Meridian of Foot Gworeum. It is peculiarity of Five Su point of Liver Meridian of Foot Gworeum, differed from the others acupoints. Symptoms of Shi-Dang-Bing appears with the abnormal pulsation of Merdian Gi(脈氣), and the special feature of Shi-Dang-Bing is the symptoms are consisted of disorders of whole body, trobles of an internal organ, and psychosomatic disorders. 2. In <Su Wen San Bu Jiu Hou Lun (素問 三部九候論)>, it is described the part of pulse feeling for Shi-Dong-Bing(是動病) of Liver Meridian of Foot Gworeum(足厥陰肝經) as ‘A region that is 2 Chon(寸) from the basic digital joint of the first toe’. This region is agree with the acupoint of Liver Meridian of Foot Gworeum in <Mai-Jing(脈經)>, <Qian-Jin-Yao-Fang(千金要方)>. And Haeng-gan(行間) Tae-chung(太衝), members of five Su-points of Liver Meridian of Foot Gworeum is situated the same region. So we suppose that the part of pulse feeling for Shi-Dong-Bing of Liver Meridian of Foot Gworeum is transformed into Haeng-gan(行間) Tae-chung(太衝), among the five Su points.

뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향

이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP Patients who were treated with electroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain from stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from 7.7±1.7 to 4.4±2.0 with pain treatment(p<0.05). In accordance with improvement of pain scores, RS and MBI scores were also improved from 2.88±0.95 to 2.13± 1.01 and from 83.0± 16.9 to 94.7±9.5(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.

Antigastritis effects of <i>Armillariella tabescens</i> (Scop.) Sing. and the identification of its anti-inflammatory metabolites

Lee, Seulah,Lee, Dahae,Park, Jun Yeon,Seok, Soonja,Jang, Tae Su,Park, Hyun Bong,Shim, Sang Hee,Kang, Ki Sung,Kim, Ki Hyun Pharmaceutical Society of Great Britain 2018 Journal of pharmacy and pharmacology Vol.70 No.3

봉독약침이 류마티스 관절염 환자의 기능회복 및 삶의 질에 미치는 영향

이상훈,이현종,박상민,김수영,박재경,홍승재,양형인,이재동,최도영,김건식,이두익,이윤호 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Objective: To evaluate the effects of bee venom acupuncture(BVA) on the rehabilitation and quality of life in rheumatoid arthritis(RA) patients Methods: Patients with RA were treated with the BVA therapy twice a week for 3 months. Tender joint counts, swollen joint counts, morning stiffness, Erythrocyte Sedimentation Rate(ESR), C-reactive protein(CRP), patient global assessment, physician global assessment, Korean health assessment questionnaire(KHAQ) were estimated and analyzed before and after BVA therapy. Results: Tender joint counts, swollen joint counts, morning stiffness showed significant decrease after BVA therapy. But, as acute inflammatory reactants, ESR showed no significant difference and CRP showed significant increase after BVA therapy. Patient global assessment physician global assessment, and KHAQ index showed significant improvement after BVA therapy. Conclusions: BVA therapy can improve rehabilitation and health-related quality of life RA patients as well as clinical symptom and signs. Further study is required in more population with large scale including acute inflammatory reaction of BVA therapy.

임상 검체에서 분리된 nontyphoid Salmonella에서의 integron의 빈도와 특징

이정은,박수진,김성한,김미나,이남용,이복권,이상오,김양수,우준희,최상호 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

Background : Nontyphoid Salmonella (NTS) is a leading cause of human food-borne enteritis, It has been known that integron, a naturally occurring gene capture and expression element, Plays an important role in the development and dissemination of multidrug-resistance. In this study, we investigated the prevalences and molecular characteristics of integrons in NTS clinical strains. Materials and Methods : Between 1995-96 and 2000-03, a total 261 NTS clinical strains comprising 39 serotypes were collected from clinical specimens. All strains were serotyped, and the MICs of ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, tetracycline, and trimethoprim were determined by agar dilution method. Integrons were detected by PCR amplification of integrase genes, and gene cassettes were determined by PCR and sequencing, Conjugation experiments were performed using E. coli J53 as a recipient. The clonal relationship was analyzed by pulsed-field gel electrophoresls (PFGE). Results : Of the 261 strains tested, class 1 integrons were present in 21 strains (8.0%). Class 2 and class 3 integrons were not found. The integron-positive rate was higher in S. Typhimurium (24.2% [8/33]) than in S. Enteritidis (2.0% [3/153]). Overall rates of antimicrobial resistance were higher in integron-positive strains. dhfr12-orfF-aadA2gene cassette was detected in 5 strains, aadA2in 4 strains, dhfr17-orfF-aadA5 in 2 strains, and addA1 in 1 strain. Ten integron-positive transconjugants were successfully selected. Among 8 integron-positive strains of S. Typhimurium, 7 had similar PFGE patterns. Conclusion: This study suggests that integrons are already playing a significant role in antimicrobial resistance in NTS. Continuous monitoring is needed to detect the emergence and spread of integron-mediated antimicrobial resistance.

봉독약침이 류마티스 관절염 환자의 관절 통증, 종창 및 급성 염증 반응에 미치는 영향

이상훈,이현종,백용현,김수영,박재경,홍승재,양형인,김건식,이재동,최도영,이두익,이윤호 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Objective In order to study the effects of bee venom(BV) on the pain, edema, and acute inflammatory reactant of rheumatoid arthritis(RA) patients. Methods Patients with RA who met the ACR(American College of Rheumatology) 1987 revised criteria for the diagnosis of RA were treated with the BV therapy twice a week for 3 months. Tender Joint counts, swollen joint counts, Visual analog scale(VAS), morning stiffness, ESR. C-reactive protein(CRP) were analyzed before and after BV therapy. Results The results as follows. 1. Tender joint counts in patients after BV therapy were significantly lower than those before BV therapy(9.0±7.9 vs 15± 11.4, p=0.002). 2. Swollen joint counts of the patients after BV therapy were significantly lower than those before BV therapy(50±61 vs 15±23, p=0.001). 3. VAS in patients after BV therapy was significantly lower than those before BV therapy(608± 17.6 vs 380± 159, p=0.000). 4. Duration of morning stiffness in patients after BV therapy was significantly reduced compared with that before BV therapy(119.1± 112.6 min vs 59.0±89.7 min, p=0.009). 5. ESR and CRP were not significantly changed before and after BV therapy, suggesting BV itself could make inflammatory reaction as well as therapeutic effect. Conclusions BV therapy improved tender joint counts, swollen joint counts and duration of morning stiffness in this study, and further study is needed on long-term effect of BV therapy.

사상체질에 따른 류마티스 관절염 환자 대조군 연구

김수영,이상훈,이현종,이두익,이윤호,이재동 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective: The purpose of this study is to examine the susceptibility of the patients diagnosed by rheumatoid arthritis to Sasang Typology. Methods: This study are planned to detect the susceptibility of the patients diagnosed by rheumatoid arthritis to Sasang Typology. In order to analyze the susceptibility of rheumatoid arthritis to Sasang Typology, 147 rheumatoid arthritis patients and 147 matched controls are assessed with QSCCⅡ question for Sasang Typology. Then the frequencies of patients by Sasang constitution are compared to those of control, which are statistically analyzed and adjusted by age, sex, smoking status, alchol intake, BMI, and economic status. Results: The demographic characteristics of the study population are similar in sex and age distribution, smoking status, and alcohol intake(p>0.05). 147 rheumatoid arthritis patients and 147 matched controls are assessed with QSCCⅡ question for Sasang constitution. Soeumin is die most susceptible to rheumatoid arthritis compared to Taeumin or Soyangin(Crude OR [95% Cl] ; 3.82 [2.19-6.64]). lt is statistically significant after adjusting age, sex, smoking status, alcohol intake, BMI, and economic status(Adjusted OR [95% Cl] ; 3.01 [1.47-6.15]). Conclusions: lt is suggested that the specific Sasang Typology associated with rheumatoid arthritis is used as its susceptibility marker and further as basic date to prevent the risk factors for rheumatoid arthritis.

광중합형 구치부 수복재료의 중합수축량과 중합수축력

박성호,이순영,조용식,김수선,이창재,김영주,이봉희,이광성,노병덕 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.4

The purpose of present study was to evaluate the polymerization shrinkage stress and amount of linear shrinkage of composites and compomers for posterior restoration. For this purpose, linear polymerization shrinkage and polymerization stress were measured. For linear polymerization shrinkage and polymerization stress measurement, custom made Linometer (R&B, Daejon, Korea) and Stress measuring machine was used (R&B, Daejon, Korea). Compositers and compomers were evaluated; Dyract AP (Dentsply Detrey, Gumbh, German) Z100 (3M Dental Products, St. Paul, USA) Pyramid (Bisco, Schaumburg, USA) Synergy Compact (Coltene, Altstatten, Switzerland), Heliomolar (Vivadent/Ivoclar, Liechtenstein), and Compoglass (Vivadent Ivoclar/Liechtenstein) were used. 15 measurements were made for each material. Linear polymerization shrinkage or polymerization stress for each material was compared with one way ANOVA with Tukey at 95% levels of confidence. For linear shrinkage ; Heliomolar, Surefil<Synergy Compact, Z100<Dyract AP<Pyramid, Compoglass F (p<0.05) For Shrinkage stress ; Heliomolar < Z100, Pyramid<Synergy Compact, Compoglass F<Dyract AP<Heliomolar HB, Surefil (p<0.05)