複合 韓藥劑 淸籬滋坎湯의 抗癌效果 및 作用機轉 糾明

Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.

배달 미니 게임 개발:"최고의 웨이터를 꿈꾸며"

김정훈,정한교,김영옥,김중곤,박정윤,윤진성,김경식 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 미니 게임은 웨이터라는 직업을 모티브로 하여서 남녀노소 누구나 재미를 느낌과 동시에 기억력 향상시켜 주는 게임제작이라는 목적아래 제작되었다.본 논문에서는 이 게임의 제작과정을 기술하고자 한다.이 게임은 제3회 AGC(한국 아마추어 게임제작 공모전)에서 우수 작으로 선정되었다.

서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

자동 형상제어용 측정롤의 특성에 관한 연구

전언찬,김중완,김순경,김문경 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.2

The continuing demand for quality products requires better understanding and improved control of the production process. And, in recent year requirements for flatness control in strip rolling have become increasingly severe because of the control for flatness of cold rolled strip is essential for further down stream processing. Also a speeds of rolling mills to meet productivity requirements puts a demanding requirement on the control of flatness of rolled strip. The demands on a total flatness control system therefore are a measuring and indication system consisting of a measuring roll that is robust, accurate, reliable and require a minimum of maintenance. The critical part of any control system is the quality of the information being provided by measurement instrument or device. It is therefore of utmost importance to have an accurate, repeatable measuring system.

강판의 자동 형상제어 장치의 특성에 관한 연구

전언찬,김중완,김문경,김순경 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.2

In this paper, the performance and functions of automatic flatness control system installed on the 4 hi-reversing mill and has been investigated under actual conditions. A new automatic flatness control system incorporates a measuring roll for measurement and correction calculations, hydraulic roll benders, selective roll cooling, and a programmable controller forinterface and data logging. The test results are as following. The more the exit steel strip thickness is thick, the smaller the I value, and the more it is thin, the larger the I value. And, a complex distribution of strip tension was controlled, for example, not only a quarter buckle but also a simple center wave and edge wave. Because the tension deviation is larger at acceleration speed and deceleration speed than steady speed. so automatic flatness control system of contact type is better to adopt over 450 m/min, automatic flatness control system reduces rapidly large flatness deviation. The maximum I value of strip has been decreased to 13 I, and defects caused by poor flatness have been drastcally decreased. And coolant temperature for work roll cooling system on the automatic flatness control system is better to adopt about 50-55℃.

Yamaguchi index에 의한 파라쿼트 중독 환자의 예후 결정

김인병,최성욱,김성중,김경수,이영수 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Study objective: To evaluate the significance of Yamaguchi index as a predictor of outcome in patients with acute paraquat poisoning Design: Retrospective chart review Setting: Two university Hospital EDs Methods: We reviewed the medical records of 47 patients with acute paraquat poisoning(18 survived and 29 died). The Eq1 was defined as : Eq1=[K+] x [HCO₃] / 0.088[Cre] mEq L¹ The patient's data were plotted as calculated Eq1 values(y-axis) against interval of time from ingestion to admission (T) (x-axis). The study patients were divided into three groups. Group A consisted of patients with Eq1> 1500-399LogT; Group B consisted of patients with Eq1: 930-399LogT < Eq1 ≤ 1500-399LogT; Group C consisted of patients with Eq1 ≤ 930-399LogT. Results: There was a significant difference among three groups (A, B and C) as far as prognosis was concerned(P<0.01). In group A, all patients survived(survival rate 100%). In group B, six of 13 patients survived(survival rate 46%). In group C, none of patients survived Isurvival rate 0%). Conclusion: Yamaguchi index is a significant predictor of outcome in patients with acute paraquat poisoning

Regular C -algebra Norm에 대한 고찰

金重熙,嚴璟漣 聖心女子大學校 1994 論文集 Vol.26 No.-

F가 r≥2의 generator를 갖는 discrete free group이고 f∈1¹(F)가 적당한 조건을 만족할 때 C*-algebra norm을 계산하는 공식이 알려져 있다. 그 공식이 F가 infinitely generated free group인 경우에도 유효함을 보이고, r≥2가 반드시 필요한 조건임을 반례를 들어보였다. Let F be a discrete free group on r≥2 generators. Under a condition on f∈1¹(F), we have a formular in [3] for computing the regular C*-algebra norm of f. In this paper, we show the validity of the formula for an infinitely generated free group F and that the condition r≥2 is essential by giving a counterexample.

Involutive Banach algebra인 l¹[G]와 Uρ(G)

金中熙,嚴璟蓮 聖心女子大學校 1991 論文集 Vol.23 No.-

요약 G가 discrete group 일때 ℓ¹[G] ⊆ Uρ(G)이며 특히 G가 discrete amenable group 일때는 ℓ¹[G] = Uρ(G)임을 보였다. We show that ℓ¹[G] ⊆ Uρ(G) when G is a discrete group and ℓ¹[G] = Uρ(G) when G is a discrete amenable group.

급성 중독 환자에 대한 역학적 고찰 : 서울과 지방의 비교

김성중,김인병,최성욱,김경수,이영수,Choi, Jong Moo 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Study objective: To compare patients with acute poisoning between urban and rural areas Design: Retrospective chart review of 217 patients with acute poisoning Setting: Two University Hospital EDs Methods: patients were divided into two groups according to hospital. The group A was 109 patients who came to ED of Asan Medical Center and the group B was patients who came to ED of Ajou University Hospital from June 1994 to February 1995. We analysed the age and sex distributions, poisoning substances. causes of poisoning and the past history of psychiatric problems in patients of the two groups. Results: Total number of patients with acute poisoning were 109 in the group A and 108 in the group B. Female was more prevalent than male in the group A and male was more than female in the group B. There was a significant difference in sex distribution between two groups. The mean age of the group A was 27.7 years which was significantly different from the mean age of the group B, 33.7 years. The age incidences in both group were highest in 2nd decade. The accidental poisoning cases were 37% in the group A and 31% in the group B. The rates of committed suicide were 7% in the group A and 22% in the group B. The most common agent of poisoning was therapeutic drug in the group A and agricultural or industrial chemical in the group B. The overall mortality was 5% in the group A and 15% in the group B. Conclusion: There were significant differences in age and sex distributions. poisoning substances, causes of poisoning and the past history of psychiatric problems between two groups.

Gelman과 Gallistel의 수세기 이론에 기초한 유아수학교육방향 : 사회극놀이를 통한 유아수학교육프로그램 활동제시

김영중,김경희 제주관광대학 2003 論文集 Vol.9 No.-

유아기 수학교육은 생활 속에서의 경험을 재구성하여 수학적 사고와 의사소통이 이루어질 수 있도록 해야 한다. 그런데 유아의 수학적 사고발달과 학습과정, 그리고 다양한 교수방법에 관한 연구결과를 바탕으로 보다 바람직한 유아수학교육의 방향을 제기하는 이론적 동향과는 달리, 많은 유아교육기관에서의 수학교육은 매우 제한되거나 적합하지 않은 방법으로 이루어지고 있다. 이에 본 논문에서는 최근에 보다 타당하고 적합한 것으로 공감을 얻고 있는 Gelman과 Gallistel의 수세기 이론에 기초하여 바람직한 수학교육의 방향을 제시하고 실제로 유아교육현장에서 적용 가능한 활동내용과 방법을 제시하고자 한다.