정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여

신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.

HPLC/FLD를 이용한 성별·연령별 혈장 homocysteine 정상치 조사

이경옥,류광석,이규범,이경옥,류광석,이규범 대한임상검사정도관리학회 1999 臨床檢査와 精度管理 Vol.21 No.1

화학적 요부 교감신경절 차단에서 한 분절 차단과 두 분절 차단의 비교

김종일,이규종,이상곤,민병우,반종석,문철준 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4

Chemical Lumbar Sympathetic Block: Comparison of One- Versus Two-needle Techniques Chul-Jun Mun, M.D., Kyu-Jong Lee, M.D., Sang-Gon Lee, M.D., Jong-Il Kim, M.D.^* Jong-Suk Ban, M.D., and Byung-Woo Min, M.D. Department of Anesthesiology, Fatima Hospital, Daegu, Korea ^*Kim Jong Il Pain Clinic, Daegu, Korea Background: It was frequently noticed in the course of performing a two-needle sympathectomy, that satisfactory spread of contrast solution could be produced by injection through only one of the needles. This led to a closer examination of the merits of single-needle technique. Methods: Forty patients were randomized into two groups. Patients in the single-needle group (n = 20) were injected at the second or third lumbar sympathetic ganglia, while patients in the two-needle group (n = 20) were injected at the second and thired lumbar sympathetic ganglia. Lumbar sympathetic blocks were performed using 3 ml of alcohol and the spread of injectate was verified with C-arm fluoroscopy. The indicators of a successful sympathetic block are increasing skin temperature, decreasing pain, and anhidrosis in the distal extremity. Results: The duration of anhidrosis was 12.2 ?? 2.6 months (mean ?? SD) in the single-needle group versus 13.6 ?? 3.6 months (mean << SD) in the two-needle group. Conclusions: As these results were not significantly different from those obtained in patients having considered to be effective for a neurolytic ;i,bar sympathectomy. (korean J Anesthesiol 2001; 41: 439~443)

전립선 비대 증상 자각군과 일반 남성군의 전립선 비대 증상, 일상생활 활동, 성생활 만족 및 안녕감 비교

이규은,오점숙,김현주,김남선 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: This study was designed to explore and compare the prostatic hypertrophoc symptoms, activities of daily living, satisfaction of sexual activities and well-being among subjects with prostatic hypertrophic symptoms and the general population. Method: One hundred subjects with prostatic hypertrophic symptoms and one hundred general persons were recruited in K medical center. The data were collected from October 20, 2001 to March 30, 2002 by structured questionnaire. Result: The results were the following; 1. The percentage of mild(0~7), moderate(8~19) and severe(20~35) symptoms between subjects with prostatic hypertrophic symptoms and general persons were 6% : 60%, 54% : 39%, 40% : 1%. 2. There was a significant difference in prostatic hypertrophic symptoms(t=12.82, p<.001), in activities of daily living(t=-7.77, p<.0001), in satisfaction of sexual activities (t=-4.80, p<.0001), in well-being(t=-4.80, p<.0001) between subjects with prostatic hypertrophic symptoms and general persons 3. There was a significant difference in activities of daily living(F=16.28, p<.0001), satisfaction of sexual activities(F=3.98, p<.05) according to prostatic hypertrophic symptoms in subjects with prostatic hypertrophic symptoms. Conclusion : According to the above findings, prostatic hypertrophic symptoms influence activities of daily living, satisfaction of sexual activities, well-being of subjects with prostatic hypertrophic symptoms negatively.

아토피 피부염 환자에서 혈청내 Cu와 Zn치 및 Cu/Zn비에 관한 연구

이성열,정현,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

아연과 구리는 피부를 포함하는 인체의 거의 모든 기관에서 일어나는 대사과정에 작용하는 metallonenzyme의 보조인자로 상당히 중요한 역할을 수행한다. 저자들은 정상대조군 10명, 전신성 아토피성 피부염 환자 16명을 대상으로 atomic absorption spectrometry를 사용하여 혈청 아연과 구리치를 측정하였고 그결과로 혈청 구리/아연 비를 구하였다. 그 결과 혈청 구리치는 대조군에 비하여 아토피성피부염 환자에서 통계적으로 의의있게 높게 나타났다. 이는 아마도 아토피성 피부염에 의한 염증반응으로 이차적으로 ceruloplasmin이 증가되어 나타난 것으로 생각되나 이 것이 명확히 규명된 것은 아니다. 혈청 아연치는 약간 감소하였으나 통계적인 유의성은 없었고 혈청 구리/아연 비의 값은 약간 증가되었으나 역시 통계적 유의성을 찾을 수는 없었다.

오세아니아 跆拳道에 관한 小考

李圭錫 龍仁大學校 1989 용인대학교 논문집 Vol.5 No.-

The aim of this paper is to provide a guide material for those who age going to the Oceanian countries as Taekwondo teachers. The body of this paper covers the current situations of Taekwondo in Australia, New Zealand, Fiji, Papus New Guinea, Samoa and Tonga, including the teaching methods and test rules along with a brief history of Taekwondo there.Besides, I suggested some directions for futured. Since the Oceanians are deelpy concerned about their health and sports, it is desirable to develop such programs as to be used with good sports facilities. Also the Taekwondo masters who are going to teach in these areas should be qualified with good capability and techniques, good personality, and competence for the related language.

병원행정직직원의 보수만족에 영향을 미치는 요인

이영석,류구수 慶山大學校 保健福祉硏究所 1999 保健福祉硏究 Vol.2 No.-

After national insurance system is launched, the number of hospital managing staffs have been increased to cover the new demands. To justify their labor costs, hospitals need efficient control in wage level of their empolyees, especially in administrative personnel. This study aims to figure out factors associated with the degree of wage satisfaction of administrative personnel in hospitals. I survey 260 administrative personnel in 5 general hospitals for the study. The results are as follows. First, high level of wage is not always related with their satisfaction of wage level. The level of satisfaction is affected by demographics such as age, sex, education level, and etc... Second, the wage level of administrative personnel is higher than other industry. However, college graduates in hospitals receives less salary than other industry's. Therefore, hospitals should raise wage level for their college graduates employees. Finally, the service years of employees is highly related with the level of wage satisfaction. As working years goes by, the level of satisfactions reduced. Therefore, hospital managers should pay more salaries for employees who have been serving long period by developing payment system such as a longevity allowance.

플라즈마를 이용한 유리섬유강화 복합절연재료의 표면처리에 관한 연구

이규철,남창우,김희대,황영한,김경석 울산대학교 1997 공학연구논문집 Vol.28 No.1

본 연구에서는 에폭시계 복합 절연재료 Glass-cloth/Epoxy 의 계면 접착특성을 향상시키기 위하여 표면처리 조건에 따라 각각 복합 절연재료를 제작하였고, 전기·기계적특성의 상관관계를 다음과 같은 실험을 행하여 비교하였다. Glass의 젖음의 정도를 평가하기 위하여 표면처리 조건에 따라 주위온도 80[℃]에서 접촉각을 측정하였고, 주위온도 및 인가전압을 변화시키면서 비유전율(εr), 유전정접(tanδ) 및 전기적 절연강도를 측정하였다. 기계적 특성을 측정한 후에 파단면의 형상을 SEM으로 분석, 검토하였다. 실험 결과, (1) 주위온도가 상승함에 따라 비유전율 및 유전정접은 증가하였고, 전기적 절연강도는 감소하였으며 플라즈마 처리함으로서 전기·기계적특성은 전반적으로 향상되었다. (2) 접촉각 측정 주위온도가 80[℃]일 때, 표면처리 조건에 따른 젖음성은 각각 다르게 나타났고 플라즈마 처리효과는 표면세정, 미세요철, 표면대전 및 젖음성의 감소와 같은 복합효과로 볼 수 있다. (4) 전기·기계적특성의 관점에서 복합 절연재료의 경화온도가 80[℃]일 때, Glass-cloth/Epoxy복합 절연재료의 최적처리시간은 3분 정도로 나타났다. The Glass-cloth/Epoxy composite insulating materials for this study have been prepared with several different surface treatmenttechniquen such as untreatment ultrasonic treatment and plasma treatment, and their electrical and mechanical characteristics have been compared each other. It has been found that plasma-treated glass has the smallest contact angle with a drop of epoxy. The plasma-treated composite materials have superior dielectric strength and mechanical tensile-strength compared to the materials subjected to other surface treatments. Also, the experiment showed that there exists an optimum plasma treatment duration for improving the interfacial characteristics of the composite insulating materials. The optimum plasma treatment durations are about 3 minutes for Glass-cloth/Epoxy at 80[℃]. Longer plasma treatment has been appeared to degrade the interfacial characteristics.

제4경추의 형태와 초경을 통한 성숙지표에 관한 연구

이규홍,황용인,김윤지,박양호,백승학,차경석 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.1

본 연구는 측모 두부 규격 방사선사진을 이용하여 성장 중인 아동의 제4경추 형태를 경추 몸체부 하연의 만곡 정도에 따라 분류하고 초경의 시기와 수완부 골 성숙 단계를 평가하여, 성장 중인 아동의 골격적 부정교합의 진단 및 악정형 치료를 위한 성장 시기 평가에 제4경추의 형태 변화가 진단의 참고자료로 활용될 수 있는지를 연구하였다. 11-14세 여자 환자 중, 같은 날짜에 촬영된 측모 두부 규격 방사선사진과 수완부 방사선사진이 모두 있는 81명을 대상으로 환자의 측모 두부 규격 방사선사진상 제4경추 몸체부 하연의 만곡 정도에 따라 세 그룹으로 분류하였다. (Group A - 제4경추 몸체부 하연의 만곡 정도가 1.05 mm 이하, Group B -제4경추 몸체부 하연의 만곡 정도가 1.05- 2.07 mm 사이, Group C -제4경추 몸체부 하연의 만곡 정도가 2.07 mm 이상)세 그룹에서 각각 제4경추 몸체부의 수직 길이, 수평 길이, 수직/수평 비율, 초경의 시기, 수완부 골 성숙 단계를 측정한 결과 다음과 같은 결론을 얻었다. 평균 수완부 골 성숙 단계는 Group A가 SMI 5.67 ± 2.57단계, Group B는 SMI 8,73 ± 2.41 단계, Group C는 SMI 10.00 ± 1.47단계로 나타났다. GroupA에서 Group B, Group C로 갈수록 제4경추의 수직 길이, 수평 길이, 수직/수평 비율, 수완부 골 성숙 단계에 있어서 각각 유의하게 더 큰 값을 보였다. 본 연구대상 아동의 평균 초경 시기는 11.64 ± 0.92세를 보였다. 제4경추 몸체부 하연의 만곡 정도, 수직 길이, 수평 길이, 수직/수평 비율은 수완부 골 성숙 단계와 각각 서로 유의한 양의 상관관계를 나타냈다. 초경을 경험한 그룹이 초경을 경험하지 않은 그룹에 비해 제4경추의 수직 길이, 수평 길이, 수직/수평 비율, 수완부 골 성숙 단계에 있어서 유의하게 큰 값을 보였다. 연구 결과 측모 두부 규격 방사선사진상 제4경추 하연의 만곡 깊이가 2.07 mm 이상인 경우 성장의 완료 단계에 가까운 시기로 나타나 이 시기의 악정형적 치료는 큰 효과를 얻을 수 없을 것으로 사료된다. Objective: This study analyzed the morphologic changes of the fourth cervical vertebra body to determine the skeletal age of orthodontic patients during growth. Methods: Eighty-one female patients aged from 11 to 14 who had cephalograms taken on the same day were examined. The subjects were divided into three groups depending on the depth of the concavity of the lower border of the fourth cervical vertebra (Group A: less than 1.05 mm, Group B: 1.05 - 2.07 mm, Group C: greater than 2.07 mm). Menarcheal timing, SMI stage, length, width and ratio of length and width of the fourth cervical vertebra body were analyzed and the following results were obtained. Results: The average SMI stage of group A,B and C were 5.67 ± 2.57, 8.73 ± 2.41, and 10.00 ± 1.47, respectively. Length, width, ratio of length and width, and SMI stage were greater in group B than group A and in group C than group B. Mean menarcheal timing was 11.64 ± 0.92 years. Concavity depth, length, width, ratio of length and width showed a significant positive correlation with SMI stage, especially with the concavity depth. Conclusion: The results of this study propose a simple method for determining the timing of orthopedic treatment by measuring the concavity depth of the fourth cervical vertebra on the cephalogram.

움직임 보상을 통한 움직임 기반의 디인테레이싱 기법

이성규,강석규,이동호 漢陽大學校 工學技術硏究所 2001 工學技術論文集 Vol.10 No.-

본 논문에서는 움직임 보상을 이용한 움직임 기반의 디인터레이싱 알고리즘을 제안한다. 정확한 움직임 추정을 위해 전처 리로서 EBMF(Edge Based Median Filter)를 사용하며 2 개의 같은 위상을 갖는 필드와 1개의 다른 위상을 갖는 필드를 이용한 새로운 BMA(Block Matching Algorithm) 움직임 보상 방법을 제안한다. 시간축 필터로서 모션 미싱 에러를 제거하기 위해 입력 영상의 움직임 영역에 따라 각각 다른 임계값을 적용하는 AMPDF(Adaptive Minimum Pixel Difference filter)를 적용하였으며 MMD(Maximum Motion Detection)와 SAD(Sum of Difference)를 이용하여 빠른 움직임 영역에서 화질을 향상시켰다. 최종적으로 잘못된 움직임 보상에 기인하는 화질의 열화를 방지하기 위한 후처리로서 움직임 보정 필터를 제안한다. 모의 실험을 통해 제안하는 방법이 기존의 방법에 비해 우수한 성능을 갖는 것을 확인하였다. In this paper, we propose a motion-adaptive de-interlacing method using motion compensated interpolation. In a conventional motion compensated method, a simple pre-filter such as line averaging is applied to interpolate missing lines before the motion estimation. However, this method causes interpolation error because of inaccurate motion estimation and compensation. In the proposed method, EBMF(Edge Based Median Filter) as a pre-filter is applied, and new matching method, which uses two same-parity fields and opposite-parity field as a reference, is proposed. For further improvement, motion correction filter is proposed to reduce the interpolation error caused by incorrect motion. Simulation results showed that the proposed method provides better performance than existing methods.