Electrochemical Deposited Hydroxyapatite Film on the Anodized Titanium

Kwon SS,Park CH,Kim BH,Ko YM 대한치과재료학회 2011 대한치과기재학회 학술대회 Vol.2011 No.5

쌍태아임신에서 치사성 이형성증 1 예

이유미,차경섭,이위현,김종욱,권계원,최윤정 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.2

We present male monozygotic twin with thanatophoric dysplasia type I concordant for long bone abnormalities and narrow thorax without cloverleaf skull. The diagnosis was made at 21weeks 3days` gestation. Prenatal diagnosis and postmortem examination showed severe micromelia, bowed long bones with "telephone-receiver" shapes and narrow thorax with short ribs in both twin. Finally it was confirmed by radiologic and pathologic examinations. The case will be presented in more details with a brief review of literature.

MR Angio 영상의 Ray Casting 가속화 Algorithm에 관한 연구

정용규,권영만,김욱동 凡石學術奬學財團 2001 凡石學術論文集 Vol.- No.5

단일 신장 섬유근성 이형성증에 의한 급성신부전

권경아 ( Kyung A Kwon ),조성 ( Seong Cho ),김성록 ( Sung Rok Kim ),김정훈 ( Jung Hun Kim ),박건태 ( Geon Tae Park ),송준휘 ( Jun Hwi Song ),임상우 ( Sang Woo Ym ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.3

Among complications of fibromuscular dysplasia are uncontrolled hypertension, aneurysm and, albeit very rare, renal failure, especially in a single kidney. We report a case of severe stenosis of fibromuscular dysplasia leading to renal failure, in need of temporary hemodialysis in 29-year-old hypertensive woman. When she was 13-year-old, she underwent a left nephrectomy because of the left renal cyst and she was treated with antihypertensive medication for several years. A few day before admission, she complained of oliguria, generalized edema and aggravated dyspnea. On the day of admission, she took emergency hemodialysis. A renal angiogram showed focal irregular stenosis in the right proximal renal artery, compatible with fibromuscular dysplasia; therefore, we performed percutaneous renal artery angioplasty. Following successful renal angioplasty, her urine output increased and creatinine level was normalized.

자궁경부암에서 cis-Platin을 포함한 복합항암요법에 의한 오심 및 구토의 조절에 있어 Ondansetron-Dexamethasone의 효과에 대한 비교분석

김승조,송승규,권용일,김미란,이유미,한상균,남궁성은 대한부인종양 콜포스코피학회 1993 Journal of Gynecologic Oncology Vol.4 No.2

Chemotherapy induced nausea and vomitting remain important concerns for patients. In recent years, many antiemetics based on diphenhydramine, dexamethasone, metoclopramide or lorazepam have eiinically demonstrable antiemetie effects. Cis-Platin, which is one of the most effective chemotherapeutic agents, produces severe emesis after its administration and delayed emesis also. Metoclopramide, which is a potent dopamine receptor antagonist, have been shown to be safe and effective single agent for the control of nausea and vomitting. But the antiemetic effects of metoclopramide was thought to be mediated by dopamine receptor blockade and so produced adverse events like as extrapyramidal reactions. Recently, Ondansetron is a highly selective 5-HT, (5-Hydroxytryptamine,) receptor antagonist that dose not have any activity at dopamine receptors. It has been shown to be an effective antiemetic activity especially when combined with dexamethasoe and also be safe and less side effects. All patients suffering from a diaease with cervical cancer were receiving cis-Platin (80 to 120 mg/ m) containing combination chemotherapy. OD( Ondan,setron (Hmg)-Dexamethasone (20mg) $gt;was given to 30 patiente. Their mean ages were 43 and 47 years old, respectively. In the OD group, Ondansetron 8mg and Dexamethasone 20mg were given by intravein 30 minutes prior to chemotherapy and administered intravenously by 8 hour intervals after chemotherapy on day 1 on days 2~3, the patients reveived Ondansetron at a dose of 8mg tid Fro the 3 days following, Ondansetron was administered as an oral dosage of 8 mg every 8 hours. In the MD group, Metoclopradmide 30 mg in normal saline 100ml and Dexamethasone 20mg were of given by intravein 30 minutes prior to cis-Platin administration for 30 minutes and administered intravenously by 8 hour intervals on days 1~3. For the 3 days following, the drugs were administered as an oral dosage of 30mg every 8 hours. In the MDL group, Metoclopramide 2mg/kg in normal saline 100ml, Dexamethasone 20mg and Lorazepam 1mg were fiven by intravein 30 minutes prior to chemotherapy and administered intravenously by 8 hour intervals on day 1. On days 2~3, the patients received Metoclopramide and Dexamethasone at a dosage of 2mg/kg and 20mg tid. For the 3 day following, Metoclopramide was administered by oral dosage of 100mg every 8 hours. In the OD group, MD group and MDL gorup, mausea was controlled in 100% of the patients(none:48.4%, mild $quot; 51.6%), 55% (5%, 50%(, 46%(13%, 33%) and vomitting was controlled in 100% of patients (complete: 87.1%, major: 12.9%), 60%(25%, 35%), 83%(43%, 40%) on day 1. On days 2 to 3, nausea was controlled in 71% of the patients(none: 12.9%, mild: 58.1%), 57.5(2.5%, 55%), 66.6%(13.3%, 53.3%) and vomitting was controlled in 80.7%(complete: 48.4%, major:32.3%), 67.5%(7.5%, 60%), 80%(23.3%, 56.7%). On days 4 to 6, mausea was controlled in 77.5% (none: 45.2%, mild: 32.3%), 77.5%(2.5%, 75%), 93.3%(33.3%, 60%), and vomitting was controlled in 87.1%(complete: 67.7%, major: 19.4%), 77.5%(20%, 57.5%), 96.7%(56.7%, 40%). The side effects of the OD group were mild with dystonic reaction(4 patients), headache(5 patients), constipation(5 patients), xerostomia(7 patients), nonspecific abdominal pain(6 patients) and cutaneous flushing(4 patients). In the MD group, expyramidal, side reaactions were seen with exrostomia(25 patinets), cutaneous flushing(26 patients), headache(10 patients), acute dystonic reaction(9 patients), restlessness(8 patients) and abdominal pain(8 patients), In the MDL group, the side effects were mild with sedation(6 patients), restlessness(1 patient) and no expyramidal reaction was seen, There is no patients who had treatment failure in 101 patients. the results showed that OD group was more effective than MD or MDL groups in a controlled envrionment of acute emesis induced by cis-Platin based combination chemotherapy. But in delayed emesis, the MDL group was the most effective regimen among the three groups. Lorazepam was an effective regimen in controlling the expyramidal side reactions

다량의 복강 내 출혈을 동반한 파열된 간세포암 : 간동맥색전술로 치료한 환자에서의 예후인자의 다중인자분석 A Multivariate Analysis of Prognostic Factors in Patients Treated with Hepatic Arterial Embolization

이정민,한영민,임성희,한현영,권근상 의과학연구소 2000 全北醫大論文集 Vol.24 No.1

Purpose : TO evaluate the safety and effectiveness of transarterial oily chemoembolization(TOCE) or transarterial Gelfoam embolization(TGE) for ruptured hepatocellular carcinoma(HCC) with massive intraperitoneal hemorrhage and to describe the most important prognostic factors of the emergency embolization. Materials and Methods : Fifty-dight consecutive patients with spontaneous rupture of HCC underwent emergency TOCE(n=28) or TGE(n=30). In TOCE group, we used infusion of lipiodol(3-10cc), adriamycin(20-50㎎), and mitomycin(2-10㎎) and followed by blockade of the hepatic arterial flow with gelatin sponge particles. In TGE group, patients received only Gelfoam embolization. The survival time was estimated from the time of the embolization by the Kaplan-Meier Method and to analyze prognostic factors, the Cox's proportional hazard regression model was used. Reuslts : Successful hemostasis was achieved in 56 patients(97%). The mean survival was 222 days in these patients. Eleven of 41 patients died of hepatic failure ; six ere in TOCE group(21%) and five in TGE group(17%). Two factors proved to significantly influenced prognosis(P<0.05) ; portal vein involvement by the tumor had the most important prognostic significance followed by higher serum total bilirubin level greater than 3.0㎎/㎗. Conclusion : Although TOCE and TGE effectively controlled the hemorrhage from the ruptured HCC, they carry a high risk of hepatic failure. In addition, tumor thrombus in the major portal vein branch and high serum total bilirubin level were the most important factor for survival.

Hypoglycemic effect of Cordyceps militaris Polymolecules in Streptozotocin-lnduced Diabetic Rats

Lee MW,Lee SJ,Lee YA,Kim JH,Cho SM,Kwon YM 大韓藥學會 2001 大韓藥學會 總會 및 學術大會 Vol.2001 No.2

여러가지 형태의 난관결찰 부인에서 고정대를 이용한 미세난관문합수술

김장흡,김수평,김진홍,임용택,김은중,정기욱,권동진,고영미 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.6

저자들은 고정대를 이용한 미세난관복원수술 후 난관의 소통성과 여러가지 난관복원수술에 영향을 미치는 요인들에 따른 임신율을 알아보고져 1988년 3월부터 1994년 2월까지 가톨릭 의과대학부속 성모병원 산부인과 불임크리닉을 내원하여 고정대를 이용한 난관복원수술을 받았던 285예중 1년이상 추적이 가능했던 110예를 분석하여 다음과 같은 결론을 얻었다. 1. 난관복원술 당시의 환자의 평균 연령은 30.4±1.3(24~39)세 였으며 불임수술 후 복원수술까지의 기간은 평균 6.5±2.7(1~16)년 이었다. 2. 과거에 시술 받았던 불임수술의 종류중 복강경 시술이 88.2%로 대부분을 차지하였고 그중 전기소작법이 47.3%, ring을 이용한 난관결찰술이 40.9%였다. 3. 시행된 난관문합술의 부위별 분포는 협부-팽대부 문합이 49.1%로 가장 많았으며 그 다음으로는 협부-협부 문합이 36.4%로 많았다. 4. 고정대를 이용한 난관복원수술 후 전체적인 임신율은 80.0%였고 그 결과를 보면 만삭분만이 40.9%, 현재 진행중인 임신이 32.8%, 자연유산이 4.5%, 자궁외임신이 1.8%였다. 5. 불임시술방식에 따른 임신율과 복원수술 후 난관길이를 보면 복강경에 의한 ring삽입의 경우 각각 93.3%와 7.3±1.2cm로 전기소작술의 69.2%와 5.1±1.3cm보다 통계적으로 의의있게 높고 길었다. 6. 난관문합 부위에 따른 난관소통성과 임신율은 협부-협부 문합에서 각각 100.0%와 90.0%로 가장 높았다. 7. 임신이 된 군의 복원수술 후 평균 난관 길이는 6.6±1.5cm으로 임신이 안된 군의 4.4±1.6cm보다 통계적으로 의의있게 길었다. 8. 복원수술 후 양쪽 난관의 길이가 모두 4cm이상인 경우, 한쪽만 4cm 이상인 경우, 양쪽 모두 4cm이하인 경우의 순으로 임신율이 통계적으로 의의있게 높은 것으로 나타났다. 9. 고정대 삽입기간(3일 또는 7일)에 따른 난관소통성과 이신율의 차이는 없었다. 10. 복원수술 당시의 월경주기(중식기 또는 분비기)에 따른 임신율의 차이는 없었다. 이상의 결과로 이미 저자들에 의한 가토 난관에서 실험결과 고정대의 잔존이 난관의 점막세포 및 난관의 운동성에 영향을 주지 않고 난관의 소통성을 높여준다는 사실이 확인된 바와 같이 영구피임 목적으로 여러가지 형태의 난관결찰 수술을 받은 부인들에서 난관복원 수술시 1주일 동안의 고정대 삽입은 난관의 소통성과 임신율을 증대시킬 뿐만 아니라 문합부위의 노출을 좋게하여 문합수술의 시간을 단축시켜 수술 후 입원기간의 단축에도 많은 도움이 될 것으로 생각된다. Many methods have been tried to raise the rate of success of tuboplasty. The purpose of tuboplasty is to maintain tubal patency, to prevent postoperative adhesion, and to prevent abortion and tubal pregnancy for term delivery. Various kinds of tubal splints have been used to maintain the tubal patency after tubal anastomosis of experimental animals and human. Therefore, this investigation was performed to examine the clinical effectiveness of the Nylon splint for women who had underwent various types of tubal ligation and wanted tubal reversal. For target of study, 110 splinted women among 285 women who had underwent the tubal reversal using splint at Department of Obstetrics and Gynecology in St.Mary`s Hospital affiliated to Catholic University Medical College from Mar. 1989 to Feb. 1995 were selected and could be traced more than one year. The were assorted by tubal ligation method, tubal length after anastomosis, splint duration, menstrual phase at the time of operation, age and postoperative hysteroalpingopragphy. The results were as follows; 1. The mean age was 30.4 years and 88.2% of them had been sterilized by laparoscopic ring or cauterization. 2. The most common site of anastomosis was isthmic-ampular portion(49.1%). 3. The overall pregnant rate was 80.0% and the outcome of the pregnancy were as follows; term pregnancy(40.9%), on going pregnancy(32.8%), spontaneous abortion(4.5%), ectopic pregnancy(1.8%). 4. The mean pregnancy rate and postoperative tubal length of women who received the tubal ligation by laparoscopic ring were(93.3%, 7.3cm), statistically significantly higher and longer than that of the women by laparoscopic cauterization(69.2cm, 5.1cm). 5. The postoperative tubal patency patency and pregnancy rate of isthmic-isthmic anastomosis were the higher rate(100%, 90%). 6. The mean postoperative tubal length of pregnant group(6.6cm) was statistically significantly longer than that of non-pregnant group(4.4cm). 7. No statistical differences were found in pregnancy rates according to the time of splint removal(3 days or 7 days after operation) and menstrual phase at that time of operation.

Nd-YAG Laser를 이용한 가토의 미세 난관 문합술에서 문합부의 조직학적 소견

김장흡,이진우,김수평,김진홍,김은중,정기욱,권동진,고영미 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.10

To study tubal adhesion, tubal patency and histologic difference under light, electronic microcopy in a site of anastomosis, authors performed three anastomosis surgery in rabbit fallopian tube;1-layer and 2-layer anastomosis in splint-not-used group(group 1) and in splint-used group(group 2) and laser anastomosis in splint-used group(group 3). 10 rabbits were used in each group, therefore the total number of experimental rabbits in 3 groups were 30. The results were as follows; 1. The degree of gross adhesion in group Ⅱ was significantly high as compared with other groups but there was no difference between left and right tube in the degree of adh- esion in each group(Table 1). 2. The incidence of tubal patency in group Ⅱ was significantly high(89%) as compared with group Ⅰ(44%). Especially, the incidence of tubal patency in group Ⅲ was significantly high(100%) but there was no difference between left and right tube in incidence of tubal patency in each group. 3. Inflammatory cell infiltration appeared in each group on optical microscopic examin- ation. Especially, fibrosis and inflammatory cell infiltration appeared more in group Ⅱ but there was no statistically significant difference. And there was no significant difference between left and right tube in each group. 4. Transmission electron microscopic examination of group I, as compared with normal control group, showed increase of microvilli and secretory granules and decrease in size of epithelial cell. Epithelial cell was morphologically transformed but maintained the original structure comparatively. TEM examination of group Ⅱ, as compared with normal control group, showed decrease of microvilli and secretory granules and flattening of epithelial cell. It showed that epithelial cell vanished in it`s original structure. TEM examination of group Ⅲ, as compared with normal control group, showed decrease of microvilli and increase of secretory granules and morphological transformation of epithelial cell. Group Ⅲ showed the resemblence to normal control group. From the above results, in reversal tuboplasty and tubal factor infertility, it is consi- dered that simple splint-used anastomosis or splint-used anastomosis with Nd-YAG laser will improve the successful rate of tubal anastomosis.

제대주위 피부종양으로 재발된 난소암 1 예

남계현,조태호,진소영,이민철,권소연,허영문,박혜경 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.10

저자들은 본원에서, 제대주위 피부종양으로 재발된 난소암 1예를 경험하였기에 간단한 문헌고찰과 함께 이에 보고하는 바이다. We present a case of recurrent cutaneous metastasis which origniated from an internal organ. The patient had been a 63 years old female who had had ovarian carcinoma stage III and total abdominal hysterectomy with bilateral salpingooophorectomy, partial omentectomy, pelvic lymphadenectomy and chemotherapy had been done. She presented a nodule measuring 1×1cm on her umbilical area. Histopathologic findings were consistent with metastatic papillary serous cystadeno-carcinoma and clinically it was associated with carcinoma of the ovary.