제 4세대 시멘트 기법을 이용한 Hybrid 인공 고관절 전치환술의 초기결과

김신윤,백승훈,박일형,김풍택,인주철,김창윤,김영모 대한고관절학회 2003 Hip and Pelvis Vol.15 No.3

제2형 당뇨병 남성 환자에서 유리 테스토스테론과 성호르몬 결합 글로블린 농도

남기덕,김영설,박철영,오승준,김덕윤,우정택,김성운,양인명,김진우,최영길 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.24 No.6

연구배경:인슐린저항성은 제2형 당뇨병과 심혈관질환의 주요한 위험 인자로 성호르몬과 상호 관계가 있다고 알려져 있다. 그러나 여성과는 달리 남성에서는 연령과 인슐린저항성에 따른 유리 테스토스테론과 성호르몬 결합 글로블린 농도의 변화에 대한 연구가 부족한 실정이다. 그러므로, 본 저자등은 제2형 당뇨병 남성 환자에서 정산인과 비교해서 유리 테스토스테론과 성호르몬 결합 글로블린 농도를 측정하고 연령에 따른 변화 정도를 알아보고자 하였다. 방법:대상 환자 모두에서 연령과 체질량지수, 총 콜레스테롤, 중성지방, 공복혈당과 인슐린 농도를 측정하였다. 혈중 유리 테스토스테론 농도는 방사면역측정법(radioimmunoassay)을 이용해서 측정하였고, 혈중 성호르몬 결합글로불린은 면역방사계측측정법(immunoradiometric assay)을 이용해서 측정하였다(Diagnostic System Laoratories, Wbster, TX, USA). 결과:1)제2형 당뇨병 남성 환자에서 정상 대조군 남성에 비해 성호르몬 결합글로불린은 104.1±35.0 vs 25.7±3.5 mole×10??로 의미 있게 높았으나(p<0.001), 유리 테스토스테론은 13.7±9.5 vs 13.6±6.5 ng/dL로 차이가 없었다. 2)연령과 성호르몬 결합 글로블린 사이의 상관 계수는 제2형 당뇨병 남성 환자에서 0.40로 중등고의 양의 상관 관계를 보였고(p<0.001), 정상 대조군 남성에서 0.11로 유의한 상관 관계를 보이지 않았다. 연령과 유리 테스토스테론 사이의 상관 계수는 제2형 당뇨병 남성 환자에서 0.08, 정상 대조군 남성에서-0.17로 모두에서 유의한 상관 관계를 보이지 않았다. 3)연령과 체질량지수를 보정한 후에 제2형 당뇨병 남성 환자와 정상 대조군 남성에서 혈중 인슐린 농도, 유리 테스토스테론과 성호르몬 결합 글로블린 사이에는 상관 관계가 없었다. 결론:제2형 당뇨병 남성 환자에서 정상 남성에 비해 성호르몬 결합 글로블린 농도가 증가되어 있었으며, 유리 테스토스테론은 차이가 없었다. 연령이 증가함에 따라 성호르몬 결합 글로블린이 제2형 당뇨병 남성 환자에서 정상 남성에 비해 증가 폭이 의미있게 컸으며, 유리 테스토스테론은 변화가 없었다. Background: Insulin resistance is a risk factor for cardiovascular disease and type 2 diabetes mellitus. There are many previous studies indicating that insulin lowers serum sex hormone-binding globulin levels, and there is inverse correlation between insulin resistance and serum sex hormone-binding globulin levels in women. However, in men, a limited number of studies are available to explain the effect of sex hormone on age and insulin. Therefore, the present study was undertaken to investigate the relationship among free testosterone, hormone-binding globulin and age in type 2 diabetic men and control subjects. Method: Age, body mass index, total cholesterol, triglyceride, fasting blood sugar, and insulin concentrations were examined on 89 type 2 diabetic men and 47 control subjects. The free testosterone level was measured by commercially available double-antibody system (Radioimmunoassay). The sex hormone-binding globulin level was also measured by commercially available double-antibody system(Immunoradiometric assay). Results: 1) Sex hormone-binding globulin level was significantly increased in patients with type 2 diabetes. However, there was no significantly difference in free testosterone level between the two groups. 2) Sex hormone-binding globulin was positively correlated with age (r=0.4, p <0.001) in patients with type 2 diabetes. Sex hormone-binding globulin and free testosterone were not correlated with age in control sujects. 3) Free testosterone and sex hormone-binding globulin concentrations were not significantly related to serum insulin concentration after adjusting for age and body mass index. Conclusions: We observed increased sex hormone-binding globulin concentration in diabetes man, and was a positively related to age. Further studies are needed to understand the relationships between age, insulin resistance, testosterone, and sex hormone-binding globulin concentrations(J Kor Diabetes Asso 24:699~707,2000).

양측성 상지훈련이 편마비아동의 환측상지 운동학습에 미치는 영향

김미현,박상범,안승택 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.3

The purpose of this study was to investigate the applicability of bilateral transfer paradigm to the rehabilitation programs for children with hemiplegia by analyzing the effect of simultaneous training of upper limbs with a tapping task on the motor learning of the affected limb. Seven children with hemiplegia performed three tasks, tapping, reaching and grasping, and stamping, in three limb conditions, affected, unaffected, and both. After six weeks of bilateral using tapping task, post-test was performed on three tasks. For the tapping task, reaction times of the affected and unaffected limb were found to be longer when they performed the task simultaneously compared to when they performed the task separately. The initial difference in reaction time between limb conditions, however, became reduced as the bilateral training proceeded. In addition, the bilateral training led to a reduction in movement time of the affected limb in post-test. These results suggest that the bilateral training may facilitate the motor learning of the affected limb by the overflow from the unaffected limb to the affected limb.

원발성 폐암 환자의 생존율에 관한 보고

김현태,이상무,어수택,박춘식,정성환,허승재,남충희,강창희,김용훈 순천향대학교 1994 논문집 Vol.17 No.4

We analysed 404 patients with primary lung carcinoma who were treated at Soonchunhyang University Hospital from July, 1985 to september, 1993 in order to investigate the survival rate and epidemiolgical properties of primary lung cancer. They were 330 males and 74 females. The most prevalent decade was seventh. In terms of cell type, the squamous cell was 225 patients (55%), and adenocarcinoma, small cell, mixed type was 21%, 19%, 4%, respectively. Among non-small cell lung carcinoma, stage Ⅲa was the most prevalent one(92%). In case of small cell carcinoma, the limited stage was 64%. The 12-, 24-, 36- month survival rate of total patients was 57%, 31%, 22%, respectivley and median sruvival time was 15 months. The 36-month survival rate tended to be longer in non-small cell lung carcinoma than that of small cell lung cancer, but there was no difference between two groups, statistically. In non-small cell carcinoma, The 36-month survival rate and meidan survival time were longer in the stage Ⅰ and Ⅱ than those of Ⅲa, Ⅲb, Ⅳ (80% versus 38%, 22%, 0%, p<0.05). According to involvement of lymph node, the 36-month survival rate was longer in NO and N1 than those of N2, N3 (61.9%, 48.7% versus 17.7%, 17.3%, p<0.05). In small cell carcinoma, The 36-month survival rate and median survival rate were higher and longer in limited stage than those of extensive stage(16.1% and 13 month vs 10% and 8 month, p<0.05). In conclusion, we report here the incidence of primary lung carcinoma and the survival rate of paients with primary lung carcinoma who were treated in Soonchunhyang University Hospital.

양수검사에서 small supernumerary marker chromosomes(sSMCs) 발견과 산전상담

문성택,김윤숙,전섭,최승도,선우재근,배동한 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

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고온·고압 처리한 키토산을 이용한 수중의 납 제거에 관한 연구

김동석,이승원,우형택 한국환경과학회 2003 한국환경과학회지 Vol.12 No.12

In order to know the effect of autoclaving on the heavy metal removal using chitosan, lead removal capacities and removal rates by various chitosans in aqueous solution were compared according to the various autoclaving time. The lead removal efficiencies and removal rates by the autoclaved chitosan were found to be on the order of 15 min(98%) > 10 min(95%) > 30 min(83%) > 5 min(53%) > 60 min(47%) > 0 min(22%) chitosan. The molecular weight of chitosan was decreased by the increase of autoclaving time. Therefore, the heavy metal removal capacity was not well correlated to the molecular weight. Langmuir isotherm was well fitted to experimental results of equilibrium adsorption on chitosan. In order to examine the process of lead removal by the autoclaved chitosan, TEMs, SEMs and FT-IR analyses were used. The surface of autoclaved chitosan was much more porous and the lead removal was mainly occurred on the surface of chitosan. The structure of autoclaved chitosan was same as that of controlled chitosan.

청소년 야외활동이 사회성 함양에 미치는 영향

김성택,김주훈 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.4

The purpose of this study was to develope a social skill training and assess its effectiveness to bring about adolescent's self-realization and to help to prevent and to resolve the adolescent problem2s This social skill training based on mind training, recreation, and adolescent training program was developed focusing on improving adolescent's self-esteem, self-effectiveness and self-concept. The research hypotheses of this study are as follows : Based on the above study, the further research and educational implications were2 proposed : First, Trained professionals are need2ed to lead the social-program. Second, it is nessessary to put this program into practical use more than once a year systematically and constantly for every student. Third, there was no significant difference between one-night-two-day and two-night-three-day program. So it would be effective to put this program into practical use as much as possible during school days. Fourth, it is nessessary to put this program into practical use to elementary school and high school student as well as boy's and girl's middle school student and study the difference among the groups. Fifth, it is needed to study further on constant effectiveness after this program. Sixth, for the development and practice of this program more professional and systematical, multi-systematic approach (education office, school, and social-educational organizations) is needed.

대두단백질 가수분해물의 특성

김동수,양승택,문윤희,류병호,김희숙,염동민,김진목 慶星大學校 1998 論文集 Vol.19 No.1

The present study was conducted to elucidate some characteristics of soy protein hydrolysates. The soy protein was obtained from defatted soy power by the treatment of n-hexan. The hydrolysates of soy protein were prepared from hydrolysis by bromelian and pepsin with the two kinds of samples of precooking for 30 min in steam oven and noncooking, and fractionated through Bio-gel P-4 column chromatography. Fractions of hydrolysates separated on the Bio-gel column chromatography were carried out to SDS-PAG electrophoresis, resulting to show some different bends from 66kD to 14.2kD of molecular weight. In addition, the fractions showed different activities of superoxide dismutase. From these results, it was found that the hydrolysates could be available to use in a lot of food industrial fields as new functional food materials because the hydrolysates had different characteristics in electrophoresis and could increase the activity of superoxide dismutase.

복어卵巢 鹽藏品 製造中의 化學的 成分 및 毒性의 變化

김동수,박지현,류병호,양승택,문윤희,김희숙 慶星大學校 1993 論文集 Vol.14 No.4

Attempts were made to investigate the levels of chemical components and detoxification of the salted puffer overies, Fugu xanthopterus, "Ggachibog" and Fugu rubripes rubripes, "Chambog", processing of solid salt mixtures containing sodium bicarbonate, during storage period. Fresh ovaries of the puffers were divided into three portions, sprinkled with a solid salt mixture containing 0,1 or 2% NaHCO₃, and were stored at room temperature for 12 weeks. The samples were examined at each step and assayed for pH, VBN, amino-N, toxicity and thin- layer chromatogram pattern. The results were summarized as follows: The values of pH were appeared to be different with the added amount of siodium bicarbonate and the values of pH were over 7.0 in a salt mixture containing 2% NaHCO₃. The change of VBN value was also revealed about 85mg/100g in A division and 90-100mg/100g in both B and C, respectively, in the salted ovary of puffer "Ggachibog" from 8 weeks. In case of salted product from the "Chamboh" ovary, it had slightly lower value than that of "Ggachibog" ovary. Also, the value of amino-N was increased until 4-6 weeks and was slowly down after the weeks in all samples. All salted products were found to lose most of the toxicity during storage period when the salt containing NaHcO₃was used for sprinkling. In the case of raw ovaries being weak toxicity below 5.0 MU/g or 24.1 MU/g, the toxicity of salted product was dropped near the level to be edible. Therefore there was significant detoxification of the puffer ovaries by the salt mixture containing sodium bicarbonate. Finally, the toxins isolated from each raw puffer ovary were detected to be TTX-related components by thin-layer chromatogrphy.

S. cerevisiae와 A. pullulans를 이용한 수용액 중의 납 제거에서 온도와 pH의 영향

김동석,서정호,우형택,송승구 대구효성가톨릭대학교 응용과학연구소 1997 응용과학연구논문집 Vol.6 No.1

The environmental factors, temperature and pH, were controlled to investigate the effects on the removal of lead in the solution by S. cerevisiae and A. pullulans. The range of experimental temperature was 20℃∼50℃, and that of Ph was 2.5∼6.5 and 2.5∼12, respectively. The optimum temperature of S. cerevisiae and A. pullulans in the removal of lead was 30℃ and 40℃, respectively. And the initial removal rate of lead by, S. cerevisiae was increased according to the increase of temperatue. The variation of the amounts of lead removal by S. cerevisiae according to the variation of temperature was steeper that by A. pullulans. The optimum pH condition was existed on both of the microorganisms, S. cerevisiae and A. pullulans, in our experimental range and that is 4.5 and 9.0, respectively.