제 3형 Gaucher세병으로 인한 진행성 근간대성 간질 2예

허경,예종수,김상진,김성은,김응규,조효근,김찬환,김현주 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

재발 또는 불응성 비호즈킨 림프종 환자에서 CDME 구제항암화학요법 후 고용량 항암화학요법 및 자가말초혈액 조혈모세포이식의 효과

김세형,한강원,배상병,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Background and objectives : The long-term survival in patients with non-Hodgkin's lymphoma (NHL) after conventional dose chemotherapy is about 35% and the rest of the patients tend to have relapse. So, in relapsed or refractory NHL, we compared the outcome of patients undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation(APBSCT) with only salvage chemotherapy of cisplatin, dexamethasone, mitoxantrone, and etoposide(CDME). Materials and methods : From June 1993 to December 1999, 25 patients with relapsed or resistant NHL were treated with CDME regimen as salvage chemotherapy. Twelve patients were received four cycles of CDME chemotherapy, and 13 patients were received high-dose chemotherapy with APBSCT following two cycles of CDME chemotherapy. Results : The median follow-up duration was 12.8 months(range:4-68). The overall response rate was 41.7% (complete response rate 25%, partial response rate 16.7%) in 12 patients with CDME only. Thirteen patients who were treated with high-dose chemotherapy with APBSCT achieved 61.5% complete response rate and 15.4% partial response rate, with an overall response rate of 76.9%. The estimated 3-year progression-free survival rate was significantly higher among patients who received high-dose therapy than patients who received CDME only(41.5% vs 20.0%, p<0.05). And, 3-year overall survival rate was significantly higher among patients who received high-dose therapy(51.3% vs 25.0%, p <0.05). Conclusions : In relapsed or refractory NHL, CDME chemotherapy is an effective salvage chemotherapy and allow peripheral blood stem cell collection. Also, high-dose chemotherapy with APBSCT following CDME is superior to CDME salvage chemotherapy only.

위발성 위장관 악성림프종 환자에서 항암치료의 효과

김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

니켈(II)의 암모늄 디티오카바메이트류 착물의 탈양성자 반응 속도와 메카니즘

김인식,김찬우,김창수 大邱大學校附設 基礎科學硏究所 1997 基礎科學硏究 Vol.14 No.1

In ethanol and pyridine, the molar extinction coefficents of nickel( II ) complexes of A, B, and C except D increase with the variation of time. From the result it is known that ethanol and pyridine may interact with the complexes, and then they may also remove a proton of the ammonium group of the ligand to form the five coordinate complexes of nickel( II )- ammonium dithiocarbamates. It is suggested that the rate-determining step is a process of deprotonation of the ammonium group in nickel( II )-ammonium dithiocarbamates complexes.

디티오카바메이트류의 수은(II)착물의 합성과 그 성질

金讚宇,金昌洙 대구대학교 기초과학연구소 1997 基礎科學硏究 Vol.14 No.1

[Hg(A)₂](A=diethanolaminedithiocarbamate), [Hg₂(B)(ClO₄)₂](B=bis(2-hydroxyethyl) ethylenediaminebis(dithiocarbamate), and [Hg(C)ClO₄]₂(C=N,N'-dimethylethylenediamine야-kthiocarbamate) have been prepared. [Hg(B)(ClO₄)₂] and [Hg(C)ClO₄]₂ are dissolved in water but [Hg(A)₂ not in water. The new mercury(II) complexes have been characterized by conductivity measurements and infrared and UV-visible spectrum studies. The possible structure of the mercury(II) complexes were proposed on the basis of spectroscopic results.

반도체 제조 공정의 진단 및 고장 예측 시스템 개발

김수희,유성록,박희찬 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

반도체 제조 공정의 진단 및 고장 예측 시스템을 개발하기 위해 PCA(Principal Component Analysis) 기법을 적용하여 데이터 분석을 하고자 하며, 이에 대한 이론적인 연구와 연구 수행 절차를 구체적으로 정립하였다. 비츄얼 C++에서 MATLAB과 PLS_Toolbox 등을 연동하여 직관적으로 시각적이며 사용자가 효율적으로 공정 현장에 적용할 수 있는 시스템을 개발하고자 한다. 지금까지 PCA와 관련된 다양한 문헌 조사를 수행하였고, 이론적인 연구를 하였다. 비쥬얼 C++ 프로그램에서 MATLAB과 PLS_Toolbox 등을 연동하기 위해 필요한 환경 설정 등을 완료하였으며, 초기 단계의 간단한 모습들을 개발하였다. 다음 단계의 모듈들은 좀 더 빠른 시간에 개발할 수 있을 것으로 기대된다. 이를 공정 현장에서 수집한 다양한 데이터에 적용하여 그 결과를 피드백하여 시스템을 수정하고 보완하고자 하며, 마지막으로 현장에 적용하고자 한다.

Ga_(0.6)Sb_(1.4)Se₃單結晶의 光傳導度 特性

宋燦日,劉炳守,李愚宣,金南伍,金亨坤 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.2

Ga_(0.6)Sb_(l.4)Se₃single crystals were grown by the Bridgman technique method, These single crystals had orthorhombic structure, and lattice constant and electric conduction type of Ga_(0.6)Sb_(l.4)Se₃single crystals was a = 11.860Å , b = 12.057Å, c = 4.103Å and p-type, respectively. Direct band gap of Ga_(0.6)Sb_(l.4)Se₃single crystals obtained from optical absorption spectrum were 1.17 eV. Photoconductivity spectrum measured at 10K showed that the photoconductivity peak in Ga_(0.6)Sb_(l.4)Se₃single crystals was located in 960 nm.

2002학년도 조선대학교 신입생 특성 분석

류찬수,김강진 조선대학교 학생지도연구소 2003 生活指導硏究 Vol.22 No.1

신도시 아파트 단지내 근린상가 업종의 수직적 기능분화에 관한 연구

송지수,김찬호 중앙대학교 건설환경연구소 2000 環境科學硏究 Vol.11 No.2

This study identifies the vertical functional differentiation of commercial facilities in apartment complexes of new towns in the microscopic landuse level. The data used in the study are originally from the previous study by Kim and Song (2000). It is properly cleaned up for the analysis in the study. This study constructs two hypotheses. They are ; 1) vertical functional differentiation of landuse in commercial facilities would exist, 2) vertical functional differentiation of lease rate in commercial facilities would exist. This paper suggests conclusions about type of industry ; 1) which is influenced of accessibility, and more influenced of lease rate, 2) which is only influenced of lease rate, 3) which is only influenced of accessibility. Consideration of horizontal location characteristics and external characteristics incoperated with vertical location characteristics would provide more reliable results and identify inherent relationships between them. It remains for future research.

스포츠의 경기실적 산정모형의 분석 : 농구의 평가공식을 중심으로 Focused on a Estimated Formula of Basketball

한필수,김찬회 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

This study was intended to examine whether the existing player assessment formulas by the sports game factors sufficiently explained/assessed a quality of games for a high reliability between the calculation-relevant parties in calculating a part of sports game results which impacted the sports player assessment, and to investigate why a difference between the sports game results and an evaluative result of player'ss actual value occurred, This analysis assumed that there was a contradiction in the player assessment for the sports game results, Searching how the players assessment has been done so for and what advantages and disadvantages of assessment are, could be a basis for structuring the assessment model. The model for the study analyzed the Power Ranking Formula per position expressed by Sports Cosun (records×(40/total playing time), Rank ER Index of NBA (ER=A-B/total number of athlete play), assessment formula of KBL's player contribution (assessed score of sports game results =extra score per item - deduction per item), NSP/SP formula of Harder, the contribution formula of Sports Chosun (contribution =points +rebound +assist +steal+ block +defense +minutes]-[error =number of failed shootings]), and ATR formula evaluating the point guard (ATR=assist (error), First, 'Sports Chosun' has the meaning of players comparison per position, but cannot do the relative comparison between positions and doesn't provide an exact mathematical information, Second, ER has a similar computing method to the formula of 'Sports Chosun' except that its mathematical information is more concrete. It is not reasonable method to evaluate all players at the same time, Third, KBL's formula accepted a diversity of assessment methods compared with other formulas, There are factors of addition/deduction even in some section, It attempted to carry out the player assessment such as granting the same weight in a concrete way, However, variables which are absolutely necessary for the assessment of underground results and extension of addition/ deduction need to be generated. Also, an objectivity of weight for a removal of voluntary grant is required, Forth, ATR formula evaluates the part of player's ability, but nobody can know whether the results are influenced by any role, Compared with other formulas, this formula is very improper, Fifth the formula of 'Sports Seoul! is almost consistent to the formula that deducts the weight in KBL formula, It is very similar to the KBL formula except an easy calculation of the formula, Consequently, a careful consideration is required, Sixth the formula of Harder seems to have the save context of flow as the formula of KBL and 'Sports Seoul'.