學校場面에서 사용되는 現行 心理檢査의 問題點

黃禎奎 漢陽大學校 學生生活硏究所 1989 大學生活硏究 Vol.7 No.-

전기 화상 환자의 수술 전 평가,고압손상과 저압손상 비교

황정원,이정기,전영태,강종만,오용석,노규정,김현철 대한정맥마취학회 2004 정맥마취 Vol.8 No.1

블리딩저감용 AE감수제의 개발 및 실용성 검토

황인성,장덕우,김규동,이승훈,한천구 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

This study is intended to develop AE water reducing agent for reduction of bleeding and investigate its practical use. According to the results, fluidity and air content increases with an increase of superplasticizer and MC viscosity agent, AE water reducing agent for reduction of bleeding is developed after determining the ratio of superplasticizer and MC viscosity agent as 3:1 to satisfy the same fluidity and air content to conventional concrete and reduce bleeding amount. As the adding ratio of developed AE water reducing agent for reduction of bleeding increases, fluidity also increases, air content satisfies the aimed range, bleeding and sinking amount of concrete are reduced, and compressive strength is almost not different from plain concrete. Therefore, developed AE water reducing agent for reduction of bleeding satisfies the aimed air content in the range of slump 12~21cm, and can also reduce bleeding amount effectively without quality deterioration of compressive strength.

페트리 네트(Petri Net)를 利用한 FMS 모델 表現 方法

하정진,황규완,김성희 동아대학교 공과대학 부설 한국자원개발연구소 1994 硏究報告 Vol.18 No.2

Petri Nets is one of the analytical technique for solution of FMS problems. It is a graphical and mathematical modeling and promising tool for describing and studying systems that are characterized as being concurrent, asychronous, dynamic, distributed and parrallel. The objective of this study is to described analytical techniques of FMS and presented for FMS model by using Petri Net.

유기주석 노출에 의한 Mysid, Neomysis awatschensis의 독성 영향

지정훈,김상규,황운기,강주찬 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4

Tests for the toxicity of tributyltin (TBT) were conducted on mysid collected from Dadepo beach, Pusan, Korea. The toxic effects of tributyltin on the survival, growth and oxygen consumption of the mysid, Neomysis awatschensis have been evaluated. Mysids were exposed to several concentrations of TBT (0, 0.56, 1.15, 3.07 and 6.12 ㎍/L) for 6 weeks. Survival rate was decreased with increases in concentration and exposure time and the reduction of more than 40% occurred at TBT concentration greater than 1.15 ㎍/L after 6 weeks. Growth rate was significantly decreased at concentrations greater than 1.15 ㎍/L Oxygen consumption rate was also decreased in a concentration-dependent way and significantly decreased to 39, 47 and 69% of the control at 1. 15, 3.07 and 6.12 ㎍/L, respectively. These results indicate that the contamination of aquatic environment by TBT has the potential to significantly reduce coastal and estuaries recruitment of mysid.

Simvastatin이 골결손부 회복에 미치는 영향

강정호,김규태,최용석,이현우,황의환 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.3

Purpose : To observe and evaluate the effects of Simvastatin-induced osteogenesis on the wound healing of defective bone. Materials and Methods : 64 defective bones were created in the parietal bone of 32 New Zealand White rabbits. The defects were grafted with collagen matrix carriers mixed with Simvastatin solution in the experimental group of 16 rabbits and with collagen matrix carriers mixed with water in the controlled group. The rabbits were terminated at an interval of 3, 5, 7, and 9 days, 2, 4, 6, and 8 weeks after the formation of defective bone. The wound healing was evaluated by soft X-ray radiography. The tissues within defective bones were evaluated through the analysis of flow cytometry for the manifestation of Runx2 and Osteocalcin, and observed histopathologically by using H-E stain and Masson’s trichrome stain. Results : 1. In the experimental group, flow cytometry revealed more manifestation of Runx2 at 5, 7, and 9 days and Osteocalcin at 2 weeks than in the controlled groups, but there was few difference in comparison with the controlled group. 2. In the experimental group, flow cytometry revealed considerably more cells and erythrocytes at 5, 7, and 9 days in comparison with the controlled group. 3. In the experimental group, soft x-ray radiography revealed the extended formation of trabeculation at 2, 4, 6, and 8 weeks. 4. Histopathological features of the experimental group showed more fibroblasts and newly formed vessels at 5 and 7 days, and the formation of osteoid tissues at 9 days, and the newly formed trabeculations at 4 and 6 weeks. Conclusion : As the induced osteogenesis by Simvastatin, there was few contrast of the manifestation between Runx2 and Osteocalcin based on the differentiation of osteoblasts. But it was considered that the more formation of cells and erythrocytes depending on newly formed vessels in the experimental group obviously had an effect on the bone regeneration.

Cone beam형 전산화 단층영상을 이용한 하악전치부 영양관의 연구

강정호,김규태,최용석,황의환 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.3

Purpose : To evaluate location, distribution, diameter, and length of the nutrient canals on mandibular anterior region using a cone beam computed tomography (CBCT). Materials and Methods : Mandibular CBCT was performed on 33 adults (18 males and 15 females) with no history of systemic disease, and any other dental surgery history. Location, distribution, diameter, and length of the nutrient canals on mandibular anterior region were radiographically evaluated. A statistical comparison was done by SPSS. Results : In the location and distribution of nutrient canals, they were found in 6.8% at labial portion above root apex, in 93.28% at lingual portion above root apex in 46.2% at labial portion below root apex, and in 53.6% at lingual portion below root apex. Nutrient canals at lingual portion above root apex were most frequently observed between central and lateral incisors, and those at labial and lingual portion below root apex were most frequently observed between central incisors. The mean diameters of nutrient canals were 0.54 mm at labial portion above root apex, 0.61 mm at lingual portion above root apex, 0.66 mm at labial portion below root apex, and 0.76 mm at lingual portion below root apex. The mean lengths of nutrient canals were 2.63 mm at labial portion above root apex, 3.74 mm at lingual portion above root apex, 4.51 mm at labial portion below root apex, and 6.77 mm at lingual portion below root apex. Conclusion : CBCT is useful device to evaluate the anatomical structure of nutrient canals on mandibular anterior region.

농촌지역 노인들의 우울증상에 관련된 요인들의 특성

송미숙,전기홍,송현종,김정은,박승구,신상건,이동훈,정성현,최연주,최완철,최민규,황재철,홍지만 아주대학교 1997 아주의학 Vol.2 No.2

This study was performed to identify risk factors for depression among the elderly in a rural area. A survey was done for the elderly living in Gosam-myenn, Ansung-kun during the period of July 28, 1997 and July 30, 1997. Demographic and sodoeconornic characteristics, and functional and health Status were assessed using a structured questionnaire, and the level of depression was measured by GDS score. The data obtained were analyzed by frequencies, percentage, t-test, ANOVA, and multiple regression, and the results were as follows: 1. The total sample consisted of 133 elderly. Of them, 47 elderly (35.4%) showed significant depressive Symptoms. 2. The GDS score was the highest for the group over 85 years of age (p < 0.05). Those living alone or widowed showed lower GDS score than those living with someone or married (p < 0.05). 3. The GDS score was the highest in the absolutely dependent group, followed by the partially dependent group, and the independent group (p < 0.01). The elderly who perceived their health Status as excellent showed the lowest GDS score. In contrast, those who had more than five chronic diseases showed the highest GDS score. 4. The elderly receiving financial and emotional support from their family or friends showed lower GDS score compared to those without any support. 5. The economically dependent group showed higher GDS score than that of independent group. 6. The elderly who involved in leisure activities showed lower GDS score than those without any involvement. 7. In terms of risk factors for depression, we found that perceived health Status, subjective economic Status, leisure activities, living arrangement and financial support were inversely associated with GDS score, whereas labor support was positively associated with GDS score. Based upon the above findings, this study suggests that these risk factors for depression in the elderly should be taken into consideration for a comprehensive mental health program for the elderly living in the rural area.

HPLC를 이용한 백삼,홍삼,홍삼농축액의 유리당 성분 및 함량 확인

맹주양;이용구;이숙재;정진아;황규찬;김태희;문용현 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

Free sugars-Fructose, Glucose, Sucrose, Maltose-were isolated from white ginseng, red ginseng, and red ginseng concentrate by HPLC. The results for the content of sugar was as follows: in white ginseng, Sucrose(30.70ppm) > Maltose (7.45ppm) > Fructose(0.42ppm) > Glucose(0.22ppm), in red ginseng, Maltose(33.65ppm) > Sucrose(8.84ppm) > Fructose (0.81ppm) > Glucose(0.43ppm), and in red ginseng concentrate, Sucrose(14.12ppm) > Fructose(9.23ppm) > Maltose(6.86ppm) > Glucose(5.87ppm). Overall results suggest that, in the contents of sugar, monosaccharide(Glucose) is lowest and disaccharide(Sucrose, Maltose) is highest, in all of ginseng.

Identification of novel therapeutic targets in the secretome of ionizing radiation-induced senescent tumor cells

HWANG, HYUN JUNG,JUNG, SEUNG HEE,LEE, HYUNG CHUL,HAN, NA KYUNG,BAE, IN HWA,LEE, MINYOUNG,HAN, YOUNG-HOON,KANG, YOUNG-SUN,LEE, SU-JAE,PARK, HEON JOO,KO, YOUNG-GYU,LEE, JAE-SEON Spandidos Publications 2016 Oncology reports Vol.35 No.2

<P>Cellular senescence is a state of irreversible growth arrest that can be triggered by multiple mechanisms, including telomere shortening, the epigenetic derepression of the INK4 alpha/ARF locus and DNA damage. Senescence has been considered a tumor-suppressing mechanism that permanently arrests cells at risk for malignant transformation. However, accumulating evidence shows that senescent cells have deleterious effects on the tissue microenvironment. Some of these effects could be attributed to the senescence-associated secretory phenotype that has the ability to promote tumor progression. However, secreted proteins from senescent tumor cells and their effects on the tumor microenvironment due to ionizing radiation (IR) exposure have not yet been fully elucidated. In the present study, we analyzed cytokines secreted from IR-induced senescent MCF7 cells by using cytokine microarrays and confirmed by western blot analysis that increased secretion of osteoprotegerin (OPG), midkine (MDK) and apolipoprotein E3 (ApoE3) occurs in these cells. Invasive, migratory and wound-healing activities were observed in MDA-MB-231 and MCF-10A cells following treatment with recombinant human OPG, MDK and ApoE3 proteins. Additionally, tube-formation activity was assessed in OPG-, MDK- and ApoE3-treated human umbilical vein endothelial cells (HUVECs). We found that OPG, MDK and ApoE3 affected cell motility and tube-formation activity. Since OPG markedly affected cell motility, we examined the effect of senescent conditioned media containing neutralizing OPG antibodies on migration and wound-healing activity. Our results demonstrated that IR-induced senescent tumor cells influence the tumor microenvironment by increasing the production of cytokines, such as OPG, MDK and ApoE3. Furthermore, these data suggest that OPG is likely a promising target capable of reducing the deleterious effects on the tumor microenvironment during radiation therapy.</P>