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황정원 대한영상의학회 1988 대한영상의학회지 Vol.24 No.5
Authors analysed the CT findings of the congenital ear anomalies of twenty-nine patients for 2 years and 3 moths. The results were as follows: 1.Most of the patients were under the age of 20 (82.7%) and prevalent in male (72,4%) 2. Clinically congenital ear anomalies were detected in 20 patients (68.9%) conductive hearing loss in 4 sensorineural hearing loss in 1 and the remained 4 patients were detected incidentally without clinical symptom. 3. In the cases of unilateral involvement of 20 patients right ear was more common (12/20), Eight of 9 bilateral involvement showed similar degree. 4. The middle ear malformations were found in 22 patients(75.9%) and bilateral in 4 patients. 26 cases of middle ear malformations had been classified by Frey into 4 groups; Group in 5 Group II in 9 Group III in 9 and Group IV in 3. 5. Incidentally found ear anomaly was lateral semicircular canal formed a single cavity with the vestibule in aoo patients(5 pts) 6. Inner ear malformations accompanying sensorineural hearing loss were found in 3 patients with bilateral involvement and middle ear malformations were accompanied in 2 patients, The degree of involvement of labyrinth was variable.
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Site-specific Mutagenesis에 의한 PRD1 DNA Polymerase의 활성부위 결정
황정원,정구홍 한국미생물학회 1991 미생물학회지 Vol.29 No.4
The PRD1 DNA polymerase is a small multi-functional enzyme containing conserved amino acid sequences shared by family B DNA polymerases. Thus the PRD1 DNA polymerase provides an useful model system with which to study structure-functional relationships of DNA polymerase molecules. In order to investigate the functional and structural roles of the highly conserved amino acid sequences, we have introduced three mutations into a conserved amino acid of the PRD1 DNA polymerase. Genetic complememtation study indicated that each mutation inactivated DNA polymerase catalytic activity.
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황정원,신상완,Hwang, Jung-Won,Shin, Sang-Wan 대한치과보철학회 1997 대한치과보철학회지 Vol.35 No.1
Proper hygienic care of removable dentures is an important means of maintaining a healthy oral mucosa on denture wearers. Denture cleansing is often poor due to improper mechanical and the inefficient chemical cleansing of dentures. Dentists and patients should realize that microbial plaque on dentures may be harmful to both the oral mucosa and the patient's general health. This literature review was aimed to evaluate materials and methods for cleansing dentures and to discuss different means of keeping dentures plaque-free. A routine denture cleansing regimen should be designed to remove and prevent reaccumulation of microbial plaque and also to remove mucin, food debris, calculus, and exogenous discoloration. The combined use of chemical and mechanical cleansing is highly recommended for patients to clean their denture effciently.
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