Feasibility and Effects of a Postoperative Recovery Exercise Program Developed Specifically for Gastric Cancer Patients (PREP-GC) Undergoing Minimally Invasive Gastrectomy

Cho, In,Son, Younsun,Song, Sejong,Bae, Yoon Jung,Kim, Youn Nam,Kim, Hyoung-Il,Lee, Dae Taek,Hyung, Woo Jin The Korean Gastric Cancer Association 2018 Journal of gastric cancer Vol.18 No.2

Purpose: Exercise intervention after surgery has been found to improve physical fitness and quality of life (QOL). The purpose of this study was to investigate the feasibility and effects of a postoperative recovery exercise program developed specifically for gastric cancer patients (PREP-GC) undergoing minimally invasive gastrectomy. Materials and Methods: Twenty-four patients treated surgically for early gastric cancer were enrolled in the PREP-GC. The exercise program comprised sessions of In-hospital Exercise (1 week), Home Exercise (1 week), and Fitness Improvement Exercise (8 weeks). Adherence and compliance to PREP-GC were evaluated. In addition, body composition, physical fitness, and QOL were assessed during the preoperative period, after the postoperative recovery (2 weeks after surgery), and upon completing the PREP-GC (10 weeks after surgery). Results: Of the 24 enrolled patients, 20 completed the study without any adverse events related to the PREP-GC. Adherence and compliance rates to the Fitness Improvement Exercise were 79.4% and 99.4%, respectively. Upon completing the PREP-GC, patients also exhibited restored cardiopulmonary function and muscular strength, with improved muscular endurance and flexibility (P<0.05). Compared to those in the preoperative period, no differences were found in symptom scale scores measured using the European Organization for Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire (QLQ-C30) and Quality of Life Questionnaire-Stomach Cancer-Specific Module (QLQ-STO22); however, higher scores for global health status and emotional functioning were observed after completing the PREP-GC (P<0.05). Conclusions: In gastric cancer patients undergoing minimally invasive gastrectomy, PREP-GC was found to be feasible and safe, with high adherence and compliance. Although randomized studies evaluating the benefits of exercise intervention during postoperative recovery are needed, surgeons should encourage patients to participate in systematic exercise intervention programs in the early postoperative period (Registered at the ClinicalTrials.gov, NCT01751880).

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

Developing Core Elements and Checklist Items for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals: A Modified Delphi Survey

Cheong Hae Suk,Park Kyung-Hwa,Kim Bongyoung,Eun Byung Wook,Kim Hyung-Sook,Kim Yong Chan,Lee Hyukmin,Jeong Su Jin,Moon Chisook,Kim Shin-Woo,Yoon Young Kyung,Hwang In Sun,Park Choon-Seon,Lee Mi Suk,Kim 대한감염학회 2023 Infection and Chemotherapy Vol.55 No.1

Background: Antimicrobial stewardship programs (ASPs) aim to optimize antimicrobial use by minimizing the spread of antimicrobial resistance. The core elements for implementing ASPs in healthcare facilities have been developed by the World Health Organization, international research group and government agencies of various countries. However, to date, there is no documented core elements for implementation of ASP in Korea. This survey aimed to establish a national consensus on a set of core elements and their related checklist items for the implementation of ASPs in Korean general hospitals. Materials and Methods: The survey was conducted from July 2022 to August 2022 by the Korean Society for Antimicrobial Therapy with support from the Korea Disease Control and Prevention Agency. A literature review was conducted by searching Medline and relevant websites to retrieve a list of core elements and checklist items. These core elements and checklist items were evaluated by a multidisciplinary panel of experts using a structured modified Delphi consensus procedure, using two-step survey included online in-depth questionnaires and in-person meeting. Results: The literature review identified 6 core elements (Leadership commitment, Operating system, Action, Tracking, Reporting, and Education) and 37 related checklist items. Fifteen experts participated in the consensus procedures. Ultimately, all 6 core elements were retained, and 28 checklist items were proposed, all with ≥80% agreement; in addition 9 items were merged into 2 items, 2 items were deleted, and 15 items were rephrased. Conclusion: This Delphi survey provides useful indicators for the implementation of ASP in Korea and suggests national policy improvement about the barriers (e.g., shortage of staffing and financial support) existing in Korea for optimal implementation of ASPs.

탈희동결건조골과 이종골이 사람태아 골모세포의 골형성에 관한 효과

윤호상,최희인,유형근 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.1

The ultimate goal of periodontal disease therapy is to promote the regeneration of lost periodontal tissue, there have been many attempts to develop a method to achieve this goal. The purpose of this study was to evaluation the effects of BBP, DLB on bone formation in human fetal osteoblasts. We examined the effect of BBP, DLB on collagen synthesis of human fetal osteoblasts. Collagen synthesis level of 5mg of BBP(5.80±0.18㎍/mg/ml), DLB(5.51±0.57㎍/mg/ml) showed significant difference compare with control group(3.58±0.35㎍/mg/ml). We also examined expression of BMP-2 by Western blot analysis. BMP-2 was expressed in both of BBP and DLB. These results suggest that BBP, DLB have an inductive effect on bone formation in vitro increasing with collagen synthesis and expression of BMP-2.

솔라셀을 이용한 그린하우스용 도난 경보 및 자동 온도 유지 관리 시스템

이정일(Jung-Il lee),윤석암(Suk-Am Yoon),윤형상(Hyung-Sang Yoon),최장균(Jang-Gyun Choi),정학수(Hak-Su Jung),윤용선(Yong-Sun Yoon),차인수(In-Su Cha) 전력전자학회 1999 전력전자학술대회 논문집 Vol.- No.-

In this paper, we transformed photovoltaic energy to electric energy using solar cells for drive power source and charged 1t with batteries. This system was programmed in a one-chip microprocessor PIC. This system can be available for the greenhouses set at countrysides and suburbs because it keeps the temperature ins1de constant and can also be used as a protection against burglars at the harvesting season. This alarm system detects the intrusion or the variation of rap1d temperature inside of the greenhouse and warns an alarm and turn on and off the siren

항정신병 약물치료하에서 주관적 안녕감을 평가하는 한국형 척도의 개발

윤진상,국승희,이형영,이철,백인호 대한신경정신의학회 2000 신경정신의학 Vol.39 No.6

연구목적 : 본 연구의 목적은 1994년 Naber 등이 개발한 38문항의 '항정신병 약물치료하에서 주관적 안녕감을 평가하는 자가평정척도(a self-rating scale to measure subjective well-being under neuroleptic tre-atment : SWN)'를 문항수를 줄이고 문항내용을 수정하여 한국형으로 개발하고자 하였다 방 법 : 204명의 정신분열병 환자들에게 22문항의 KmSWN과 General Health Questionnaire/Quality of Life-12(GHQ/QL-12)를 실시하였고, 사회인구학적 및 임상적 특징을 조사하였다. 자료분석에는 척도에 대한 반응과 정보가 신뢰로운 176명의 자료를 포함시켰다. 첫째, KmSWN의 신뢰도와 타당도를 평가하였다. 둘째, KmSWN총점과 사회인구학적 및 임상적 특징의 관계를 조사하였다. 끝으로 KmSWN의 총점을 예측하는 변인들을 알아보기 위해 KmSWN총점과 유의한 상관이 있는 변인들을 독립변인으로 하고 KmSWN총점을 종속변인으로 하여 단계적 중다회귀분석을 실시하였다. 결 과 : 22문항의 KmSWN중 세문항은 내적 일치도가 낮아서 추후분석에서 제외되었다. 19문항의 KmSWN(KmSWN-19)은 반분신뢰도(.91), 문항간 상관의 평균(.38), 내적 일치도(Cronbach alpha .92)가 높았다. 요인분석에서는 '불만족', '신체 및 정신기능', '정서조절 및 자기통제'의 3개요인이 추출되었다. KsSWN-19총점과 GHQ/QL-12총점간의 상관은 -.83으로 공존타당도가 높았다. 사회인구학적 및 임상적 특징중 연령, 용돈, 사회경제적 수준, 과거 입원횟수, 투약에 대한 순응 투약에 대한 만족도는 KmSWN-19 총점과 정적 상관이 있었던 반면, 질병의 심도, 파킨슨 증상의 심도, 지연성 운동장애의 심도, 투약횟수 및 투약을 빠뜨린 횟수는 KmSWN-19 총점과 부적 상관이 있었다, 단계적 중다회귀분석결과, KmSWN-19총점을 유의하게 예측하는 변인은 투약의 만족도, 투약을 빠뜨린 횟수 및 용돈이었으며, 변량의 24%를 설명하였다. 결 론 : KmSWN-19는 정신분열병 외래환자의 주관적 안녕감을 측정하는 자기평정척도로서 신뢰롭고, 타당하며 실용적임이 확인되었다. 아울러 KmSWN-19는 항정신병 약물과 관련한 주관적 안녕감에만 특이한 척도가 아니라, 척도에 응답할 수 있는 모든 정신분열병 환자나 기타 정신증 환자들에게 적용할수 있는 일반적 척도임이 시사되었다. 한편, KmSWN-19총점에 대해 독립변인들의 설명변량이 크지 않는 점을 주관적 안녕감 혹은 삶의 질의 평가에서 개인의 가치나 신념, 성격특성 같은 개인내적 특성을 고려해야 할 필요성이 있음을 시사한다. Objective : The purpose of this study was to develop the Korean modification of SWN(KmSWN), based on the original 38-item SWN(a self-rating scale to measure subjective well-being under neuroleptic treatment)by Naber et. al. In 1994, but containing the reduced number of items and the modified content. Methods: The KmSWN with 22 items and General Health Questionnaire/Quality of Life-12(GHQ/QL-12) were administered to 204 out-patients with schizophrenia. Also, their socio-demographic and clinical characteristics were investigated. Data analyses were conducted based on 176 patients whose responses to the scale, as well as whose related informations, were reliable. First, the reliability and validity of KmSWN were assessed comprehensively. Second, the relationships between the total score of KmSWN and the sociodemographic and clinical characteristics were examined. Finally, in order to identify the predictable variables on the total score of KmSWN, the stepwise multiple regression analysis was conducted, where the inde-pendent variables were already shown significant correlations with the total score of KmSWN. Results : Three of 22 items of KmSWN were excluded from the following analysis due to their poor internal consistency. KmSWN comprised with 19 items(KmSWN-19) showed high levels of spilt-half reliability(.91), mean of inter-item correlations(.38) and internal consistency (Cronbach alpha .92). Factor analysis of the KmSWN-19 revealed that a three-factor solution accounted for 100% of total explained variance. The three factors were interpreted as 'diss-atisfaction','physical and mental functioning', 'emotional regulation and self-control', The concurrent validity of KmSWN-19 with GHQ/QL-12 was very high(-.83). Of the socio-demographic and clinical characteristics, age, disposable money, socioeconomic level, number of previous hospitalizations, compliance with medication and satisfaction with medication were positively correlated with the total score of KmSWN-19, while severity of illness, severity of parkinsonism, severity of dyskinesia, administration frequency of medication and omission number of medication were negatively correlated. However, the total score of KmSWN-19 was not correlated with medication, the omission number of medication and the disposable money were significantly contributed to the total score of KmSWN-19, and they explained 24% of the variance. Conclusions : The above findings indicated that KmSWN-19 was a reliable, valid and pra-ctical self-rating scale to measure subjective well-being in out-patients with schizophrenia. Moreover, KmSWN-19 seemed to be a general scale applicable to all the schizophrenic or other psychotic patients if they were able to complete it, rather a specific scale only for the patients undergoing the neuroleptic treatment. Based on the results of the predictable variables on the total score of KmSWN-19, one may argue that intra-individual characteristics such as value, belief and personality traits, although they were not evaluated in this study, should be considered in assessing subjective well-being or the quality of life.

요골동맥을 이용한 관동맥 조영술의 유용성

윤정한,이승환,이한요,김장영,김일회,최윤종,이형준,이명옥,김승년,황성오,홍인수,최경훈 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.10

Moon, Yoon-Hee

문윤희,권영창,정인철,이형걸 慶星大學校 1995 論文集 Vol.16 No.2

Frozen beef loin imported from Australia was stored as 2℃ after thawing, then evaluate to improvement of raw meat aroma and palatability of cooked meat by sensory evaluation. To improvement of raw meat aroma and palatability of cooked meat of thawed beef were confirmed for the reason of conditioning after thaw as a result of myofibrillar fragmentation index(MFI) and Mg-ATPase activity of myofibril. Sensory evaluation of raw meat aroma and tenderness on frozen imported beef loin stored at 2℃ after thawing had good in all during cold storage, MFI and Mg-ATPase activity increased, therefore frozen beef loin could recognized to conditioning during stored at 2℃ after thawing. Cold storage after thawing of frozen imported beef loin can improve its cooked aroma and tenderness in case that insufficient conditioning is the reason for its low palatability, and the improvement of palatability on the cooked meat appeared to be greater in aroma than taste. In case of amino acid composition, aspartic acid, threonine, glutamic acid and alanine of imported beef loin stored 7 days after thawing were showed significantly(p<0.05) higher than that stored 0 day after thawing, total amino acid composition of imported beef loin stored 0,3 and 7 days after thawing were 148.40, 171. 06 and 188.99mg/g, respectively.

DC Servo Motor를 이용한 초정밀 위치결정기구의 컴퓨터 시뮬레이션 및 제어성능 평가

박기형,김재열,윤성운,이규태,곽이구,송인석,한재호 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.6

Recently, High accuracy and precision arc required in various industrial field especially, semiconductor manufacturing apparatus, Ulna precision positioning apparatus, Information field and so on. Positioning technology is a very important one among them. As such technology has been rapidly developed, this field needs the positioning accuracy as high as submicron. It is expected that the accuracy of 10nm and 1nm is required in precision work and ultra precision work field, respectively by the beginning of 2000s. High speed and low vibration arc also needed. This work deals with the design method and control system of Ultra precision positioning apparatus. Control perfor-mance and stability analysis were performed in advance by modeling and designing the controller with Simulink.

3D stack package의 구조해석과 모아레 측정법을 이용한 결과 비교

윤형석(Hyung Seok Yoon),최광성(Kwang Seong Choi),배현철(Hyun Cheol Bae),임병옥(Byeong Ok Lim),엄용성(Yong Sung Um),문종태(Jong Tae Moon),전인수(In Su Jeon) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11

Semiconductor devices become smaller, higher density and performance required is increased interest in this issue is a 3D package technology; Thermo-mechanical reliability was interested in. Coefficient of thermal expansion mismatch between dissimilar materials of the package takes the biggest factors in life are most interested in TSV (through silicon via) and the solder joints were treated with the finite element method. Bump chip thickness, interposer thickness, underfill's material property package of several factors that affect the reliability of CTE of underfill for the study was conducted by the largest change in stress was found to appear. We were aiming to optimize the design, production and real samples by comparing the results of the Moire measuring the reliability of numerical results have been verified.