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      • 排卵湯이 白鼠의 排卵에 미치는 影響

        황태원,박재웅,위석,조한백,유심근 한국전통의학연구소 2002 한국전통의학지 Vol.12 No.1

        Baelantang(BLT) is used in female infertility caused by ovulation disorder. An attempt was to evaluate the influences, of BLT on the serum concentrations of FSH, LH, estradiol(E_(2)) and progesterone, the histological and optical changes of ovary, ovary weight of rats. The results of the study were as follows : 1. Blood FSH level increased experimental group as compared with control group on 7th day, which showed no efficacy. 2. Blood LH level increased in experimental group as compared with control group on 7th day and decreased 14th day, which showed no efficacy. 3. Blood E_(2) level decreased in experimental group as compared with control group on 7th day and increased 14th day, which showed no efficacy. 4. Blood progesterone level increased in experimental group as compared with control group on 7th day and decreased 14th day, which showed no efficacy. 5. In histological observations of ovary, ovulation increased in experimental group as compared control group on 7th day and on 14th day, which showed no efficacy. 6. In optically observations of ovary, weight of ovary increased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. According to these results, BLT did not influence on the ovulation and ovary of rats.

      • KCI등재

        커피설기의 재료 배합비에 따른 품질 특성 및 상품화 방안

        서한석,김세희,한복려,황인경 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.2

        The purpose of this study was to investigate the instrumental and sensory characteristics of coffee-sulgi(rice cake) with different ratios of the ingredients; coffee(30㎖, 40㎖ and 50㎖ of espresso and instant coffee) and sugar(50g and 75g). A commercial scheme for coffee-sulgi was also investigated. The optimal mixing ratios of coffee-sulgi with added espresso were rice flour 500g, salt 5g, espresso 40㎖ and sugar 75g. Those of coffee-sulgi with added instant coffee were the same. As the sensory intensities of coffee aroma, coffee taste, sweetness, moistness, elasticity, color acceptance for coffee-sulgi and overall acceptance for quality were enhanced, the overall preference for coffee-sulgi was increased. In addition, overall preference was positively correlated with adhesiveness and a-value of instrumental characteristics, but negatively correlated with cohesiveness and L-value. In coffee-sulgi with added espresso, intensities of coffee aroma, browniness, coffee taste, color acceptance for coffee-sulgi, overall acceptance for quality and overall preference were higher than those of coffee-sulgi with added instant coffee. In this point, gourmet coffee-sulgi with added espresso and universal coffee-sulgi with added instant coffee could be differentiated in the coffee-sulgi markets. In conclusion, this study of coffee-sulgi and the differential scheme for the market will be useful to expand rice processing, enhance the intake of rice cakes and provide a reference for commercialization of rice cakes.

      • 폐굴껍질을 혼입한 콘크리트의 기초적 성질에 관한 실험적 연구

        어석홍,이형진,황규한 國立 昌原大學校 産業技術硏究所 2002 産技硏論文集 Vol.16 No.-

        The purpose of this study is to investigate the fundamental properties of concrete mixed with crushed oyster shells(OS) as coarse or fine aggregates. For this purpose, five reference mixes with W/C ratios of 0.4∼0.6 at intervals of 0.05 were considered. The replacement proportion of OS was varied with ratios of 0, 10, 30, 50 and 100% by volume of fine or coarse aggregate in the reference mixes. OS was washed and crushed for using as aggregates. New chemical reaction between crushed OS aggregate and and cement paste was tested through XRD and SEM analysis. The compressive and flexural strength properties were considered. Strength tests were carried out at the ages of 1, 3, 7, 14, and 28 days. The variation of workanility, air content and density, drying shrinkage of the specimens with different proportions of OS were also studied. Finally, the hollow concrete block using OS as a substitute material for fine aggregate was made for testing the application of OS. Experimental results showed that any new chemical reaction did not occur due to mixing crushed OS in ordinary concrete. The workability and strengths decreased with increase in proportion of OS. The same trend was observed in density and unit weight, but air content increased due to the inherent shape and texture of OS, which showed a possibility to produce light weight concrete with low strength by using OS as coarse aggregates for concrete. Tests on hollow concrete block showed that the compressive strength and absorption ratio were satisfied with quality requirements when the fine aggregate was substituted with OS up to 50% in volume.

      • KCI등재

        서울 시내 커피전문점에서 판매되는 커피의 이화학적 특성 및 항산화성 비교

        서한석,김수희,황인경 한국조리과학회 2003 한국식품조리과학회지 Vol.19 No.5

        The physicochemical properties and antioxidant activities of commonly consumed espresso and regular coffees, at coffee shops in downtown Seoul, were investigated. Moreover, the characteristics between chain type coffee shop and owner shops were compared using t-tests. The serving temperature and volume of espresso were lower than those for regular coffees. Whereas, the pH and total acidity of espresso were higher than those for regular coffees. Coffees from chain shops, in particular, had a significantly higher pH and lower total acidity than those from owner shops. The L, a and b values of the regular coffees were higher than those of the espresso coffees. With the exception of the a value of regular coffees, all the color values of the coffees from owner shops were higher than those from the chain shops. The intensity of the brownness, soluble solid contents and total phenolic contents of the espresso coffees were about 7-8, 8-9 and 4 times higher, respectively, than those of regular coffees. In addition, the free radical scavenging capacities and antioxidant activities of the espresso coffees, using a chemiluminescence assay, were higher than those of regular coffees. Espresso coffees from chain shops, especially, had higher activities of free radical scavenging than those from owner shops. In conclusion, the characterics of coffees from chain shops were significantly different from those from owner coffee shops.

      • 사마귀류 추출물의 생물학적 활성 비교

        허진철,황재삼,강석우,윤치영,이상한 慶北大學校農業科學技術硏究所 2007 慶北大農學誌 Vol.25 No.-

        In order to investigate the availability of insect resources for agrobiotechnological or medical purposes, we examined antioxidant (DPPH and FRAP assay) and cell viability by oxidant stress and NO inhibition assay by treatment of the extracts of Statilia maculata Thunberg, Tenodera angustipennis Saussure and Tenodera aridifolia Stoll. We found that Tenodera angustipennis Saussure and Tenodera aridifolia Stoll extract (DW, etanol, methanol) had high levels of anti-oxidant activity, whereas Tenodera aridifolia Stoll extract showed increased cell viability by hydrogen peroxide and inhibition of NO production. These findings suggest that Statilia maculata Thunberg, Tenodera angustipennis Saussure and Tenodera aridifolia Stoll, extract have potentials to be developed for agrobiotechnology or medicinal use, indicating that mechanistic study including inhibition against molecular inflammation will show a possibility for the development of useful insect resources.

      • KCI등재

        유자액을 이용한 소스의 이화학적 특성 및 저장성

        유경미,서우영,서한석,김완수,박재복,황인경 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.4

        The purposes of this study were to investigate the physicochemical characteristics and storage stabilities of various sauces with added Yuza(Citrus Junos). Yuza consisted of three parts: peeled (46.17%), fleshed (43.74%) and seeded (10.09%). Yuza juice revealed 11.33% extraction yield, pH 2.85, 4.18% total acidity, 11° Brix, 1.16% transmittance and 2.63° Brix/acid ratio. Five kinds of sauces with added Yuza juice were Yuza red pepper paste sauce, Yuza soybean sauce for meat, Shahu shabu Yuza sauce, Korean Yuza vegetable sauce and Japanese Yuza soybean sauce. These sauces showed slight changes in pH, total acidity, total bacterial counts and overall sensory characteristics during storage period (60 days). In conclusion, Yuza juice could be applied to various sauces, which remained usable for 60 days.

      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • SCISCIESCOPUS

        Enhanced SMAD1 Signaling Contributes to Impairments of Early Development in CFC-iPSCs.

        Han, Kyu-Min,Kim, Seung-Kyoon,Kim, Dongkyu,Choi, Jung-Yun,Im, Ilkyun,Hwang, Kyu-Seok,Kim, Cheol-Hee,Lee, Beom Hee,Yoo, Han-Wook,Han, Yong-Mahn AlphaMed Press 2015 Stem Cells Vol.33 No.5

        <P>Cardio-facio-cutaneous (CFC) syndrome is a developmental disorder caused by constitutively active ERK signaling manifesting mainly from BRAF mutations. Little is known about the role of elevated ERK signaling in CFC syndrome during early development. Here, we show that both SMAD1 and ERK signaling pathways may contribute to the developmental defects in CFC syndrome. Induced pluripotent stem cells (iPSCs) derived from dermal fibroblasts of a CFC syndrome patient (CFC-iPSCs) revealed early developmental defects in embryoid body (EB) development, β-catenin localization, and neuronal differentiation. Both SMAD1 and ERK signalings were significantly activated in CFC-iPSCs during EB formation. Most of the β-catenin was dissociated from the membrane and preferentially localized into the nucleus in CFC-EBs. Furthermore, activation of SMAD1 signaling recapitulated early developmental defects in wild-type iPSCs. Intriguingly, inhibition of SMAD1 signaling in CFC-iPSCs rescued aberrant EB morphology, impaired neuronal differentiation, and altered β-catenin localization. These results suggest that SMAD1 signaling may be a key pathway contributing the pathogenesis of CFC syndrome during early development.</P>

      • KCI등재

        Cytoplasmic Anti-Neutrophil Cytoplasmic Antibody Positive Diffuse Alveolar Hemorrhage Associated with Methimazole

        ( Han Seok Ryu ),( Joo Hun Park ),( Seung Soo Sheen ),( Tae Hwan Kim ),( Sung Dam Han ),( Ju-yang Jung ),( Chang-hee Suh ),( Sung Chul Hwang ) 대한류마티스학회 2017 대한류마티스학회지 Vol.24 No.4

        Diffuse alveolar hemorrhage (DAH) is a life-threatening condition associated with many disorders. Here, we report a case of 59-year-old female who had diffuse alveolar hemorrhage associated with methimazole. She had been treated with methimazole for two weeks due to the recurrence of Grave`s disease, before visiting the emergency room. She had to be intubated on the 3rd day of hospitalization because of unabated massive hemoptysis and rapid progression of diffuse alveolar infiltration on chest radiographs. Since her clinical condition improved substantially after cessation of methimazole and steroid pulse therapy, she was extubated on the 9th day of hospitalization and then discharged. After discharge, DAH did not recur with cessation of steroid and she had radioactive iodine therapy for her Grave`s disease. This was a rare and interesting case of life-threatening DAH associated with cytoplasmic-antineutrophil cytoplasmic antibody and methimazole. (J Rheum Dis 2017;24:236-240)

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