PRRSV와 Staphylococcus hyicus 복합감염에 의한 돼지 귀 괴사 증후군 증례 보고

이승희,정지열,김성희,김종완,박중원,강대영,허지웅,정예지,소병재,윤순식,Lee, Seunghee,Jung, Ji-Youl,Kim, Seong-Hee,Kim, Jong-Wan,Park, Jung-Won,Kang, Dae-Young,Her, Ji-Woong,Jeong, Yea-Ji,So, Byung Jae,Yoon, Soon-Seek 대한수의학회 2017 大韓獸醫學會誌 Vol.57 No.2

Porcine ear necrosis syndrome is characterized by erosive and ulcerative lesions at the margin or tip of the pinna. Three growing pigs of different ages exhibited retarded growth accompanied by reddening and necrosis of ear prior to death. Gross examination showed reddening, swelling, black discoloration, scaling, and variable-sized yellowish materials and edema in ear cross section. Microscopically, thrombosis, abscess, ulceration, epidermal hyperplasia, and dermal pyogranulomatous inflammation with an intralesional bacterial colony were observed. Staphylococcus hyicus was isolated in all pigs' ears and porcine reproductive and respiratory syndrome virus was detected by PCR and immunohistochemistry.

의학교육에서의 가르치는 것과 배우는 것의 의미

이승희,Lee, Seung Hee 연세대학교 의과대학 2009 의학교육논단 Vol.11 No.2

Teaching and learning were carried out long before the word "education" was coined. As teaching and learning became more universal, the word "education" was construed as a social promise, and there was a general consensus as to what it denoted. Many university professors will most likely have great confidence and expertise with respect to "teaching" in their area of specialization, and they believe that they are fulfilling a social promise. However, how much expertise do they have in actually making students "learn"? How concerned are professors about enabling students to utilize their potential and talents to cultivate their learning abilities and to adjust to the different demands of various fields? The same issue arises in medical education. To what extent can professors' teaching heighten students' sense of purpose and motivation to learn? With regard to increasing learners' initiatives, the learning model of constructivism presupposes that learners are active and creative, have their own personalities, and possess unlimited learning potential. The PBL being carried out in medical schools today is a form of study that can take advantage of these aspects of learners. They can maximally widen the range of students' development through many intellectual activities and solve difficult problems by either sharing or critiquing the thoughts and ideas of others. The acts of teaching and learning that have been carried out for thousands of years remain difficult to this day and must be ceaselessly deliberated and researched by experts in the field of education. Just as good teachers are required to produce good learners, we must give ourselves room to rethink the basis of education in order to maximize effective and efficient learning.

폐쇄성 수면 무호흡증의 수면의 질 평가와 액티그라프의 역할

이승희,이진성,정도언,Lee, Seung-Hee,Lee, Jin-Sung,Jeong, Do-Un 대한수면의학회 2007 수면·정신생리 Vol.14 No.2

목 적:활동기록기는 활동도를 기록함으로써 수면과 각성을 판별할 수 있다. 수면다원검사와 달리 활동기록기는 싸고 간편하다. 그러나 뇌파를 포함한 여러 신호를 가지고 수면단계를 판별하는 수면다원검사와 달리 활동기록기는 기술적인 한계를 지니고 있다. 이 연구에서는 대표적 수면장애인 폐쇄성 수면무호흡증 환자에서 활동기록기와 야간수면 다원검사간에 수면변수를 비교하였다. 방 법:2004년 11월부터 2006년 3월까지 서울대학교 병원 수면의학센터에서 수면다원검사와 손목 활동기록법을 동시에 시행한 환자를 대상으로 하였다. 폐쇄성 수면 무호흡증 환자 89명, 폐쇄성 수면 무호흡증과 주기성 사지운동증이 동시에 있는 환자 21명이었다. 결 과:폐쇄성 수면 무호흡증 환자를 호흡장애지수(respiratory disturbance index, RID)에 따라 나누어 분석했을 때 경도(RDI<15), 중등도($15{\leq}RDI$<30) 환자군 및 주기성 사지운동증을 동반한 환자군에서는 활동기록법과 수면다원검사에서 얻어진 총수면시간 및 수면효율에 차이가 없었다. 폐쇄성 수면 무호흡증이 심한($30{\leq}RDI$) 환자에서 는 야간수면다원검사에 비해 활동기록법에서 얻어진 총수면시간이 유의하게 짧고 수면효율은 낮았다. 이들 모두에서 활동기록법과 야간수면다원검사에서 측정된 수면변수간에 유의한 양의 상관성은 관찰되지 않았다. 수면다원검사에서 얻은 총수면시간과 활동기록법에서 얻은 총수면시간의 차이와 호흡장애 지수(RDI)는 양의 상관관계를 보였으며 수면다원검사에서 얻은 수면효율과 활동기록법에서 얻은 수면효율의 차이와 호흡장애 지수(RDI)도 양의 상관관계를 보였다. 결 론:심한 폐쇄성 수면무호흡증 환자에서 활동기록기만으로 수면의 질을 평가해서는 안될 것이다. 경도와 중등도의 무호흡증에서는 활동기록기가 스크린 도구로 도움이 될 것이다. Background: Actigraphy is a reliable and valid method for assessing sleep in normal, healthy populations, but it may be less reliable and valid for detecting disturbed sleep in patients. In this study, we attempted to assess the utility of actigraphy in the estimation of sleep quality in patients with obstructive sleep apnea syndrome (OSAS), a major sleep disorder. Method: We analyzed the data of patients who underwent polysomnography (PSG) and actigraphy simultaneously for one night at the Center for Sleep and Chronobiology, Seoul National University Hospital from November 2004 to March 2006. Eighty-nine subjects with OSAS alone and 21 subjects with OSAS and periodic limb movement disorder (PLMD) were included for final data analyses between groups. Polysomnographic and actigraphic data were also compared. Results: In subjects with mild OSAS (RDI<15), modretae ($15{\leq}RDI$<30), and OSAS with PLMD, PSG and actigraphy did not show significant difference in total sleep time and sleep efficiency. However in severe ($30{\leq}RDI$) OSAS subjects, PSG and actigraphy showed significant difference in total sleep time and sleep efficiency. In all patients, no correlations were found between sleep parameters from PSG and from those using actigraphy. Conclusions: We suggest that in severe OSAS patients, PSG is the diagnostic tool. In mild and moderate cases, actigraphy might be used as a screening tool.

섬유주세포에서 Erythropoietin이 일산화질소의 생성에 미치는 영향

이승희,김재우,Seung Hee Lee,Jae Woo Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.12

Purpose: To investigate the effects of erythropoietin (EPO) on the production of nitric oxide in cultured human trabecular meshwork cells (HTMC). Methods: Primarily cultured HTMC were exposed to 0, 0.5, and 1.0 U/ml EPO using serum-deprived media for 2 days. Production of nitric oxide and cellular survival were assessed with Griess assay and MTT assay, respectively. Expression of EPO mRNA receptor and activity of eNOS were assessed with RT-PCR. Results: EPO did not affect the survival of HTMC (p > 0.05). EPO increased the production of nitric oxide (p < 0.05) accompanied with increased eNOS activity. Conclusions: EPO had no effect on the cellular survival under serum-deprived conditions. EPO increases the production of nitric oxide by increasing eNOS activity. J Korean Ophthalmol Soc 2011;52(12):1514-1518

알코올로 인한 Wernicke disease의 치험 1례

이승희,라수연,김민석,정희,이유경,이태훈,김경훈,김성균,Lee, Seung-Hee,Ra, Su-Yeon,Kim, Min-Seok,Jung, Hee,Lee, Yu-Gyung,Lee, Tae-Hoon,Kim, Kyeong-Hun,Kim, Sung-Gyun 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4

Wernicke Disease is well known of nutriotional disorders Wernicke Disease is charaterized by ataxia, confusion and oculomotor disturbance. We diagnosis one patient, who has ataxia, confusion and oculomotor disturbance as Jusang(酒傷), and gave saenggangunbi-tang, bojungchiseub-tang and samchulgunbi-tang. We observed that clinical symptom and Liver function were improved by these herbal medicine Therefore We consider Wernicke Disease as Jusang(酒傷) and further reports with many case, however, will be needed.

NGN 다중 네트워크 및 어플리케이션 서비스 제공자 환경에서 융합서비스를 위한 서비스 시나리오

이승희,Lee, Sung-Hui 한국정보통신학회 2008 한국정보통신학회지 Vol.9 No.2

제천전(濟川煎)과 약물(藥物) 가감(加減)이 흰쥐의 사하작용(瀉下作用)에 미치는 영향(影響)

이승희,이상준,박수연,김홍렬,박성규,Lee Seung-Hee,Lee Sang-Jun,Park Soo-Yeon,Kim Hong-Yeoul,Park Seong-Kyu 대한한의학방제학회 2002 大韓韓醫學方劑學會誌 Vol.10 No.1

We have examined the purgative effect of three Jechun-jun formulas in sprague dawley(SD) rat. Three jechun-jun formulas were Jechun-jun(Sample I ) and augmented Jechun-jun(Sample II) and augmented Jechun-jun add rhubarb(sample III ). We examined the amount and the humidity of feces in rat. The experimental animals were devided into four groups. as control group and three Jechun-jun (sample I, II, III). We administerd the water extract of sample I, II, III to rat per oral for 8days long. After every 24hours measured the amount of wet feces from rats in metabolic cage. Humidity rate of feces from rat was at first measure wet feces for 24hours (W) and measure dried feces (W1) and then we consider W-W1 as humidity. High humidity rate means constipation changes into moistening stool. The amount of wet feces and humidity rate of feces in rats were increased in sample I, II, III. Sample I has highest humidity rate of feces. so showed strong moistening effect. Sample II has mild effect in treating constipation. sample III has most amount of wet feces. in conclusion Jechun-jun has an effect of moistening stool. and augmented Jechun-jun add rhubarb has strong purgative effect.

포털사이트의 지각된 서비스 품질이 후속 행동에 미치는 영향에 관한 연구

이승희,김혜경,Lee, Seung-Hee,Kim, Hye-Kyoung 한국디지털정책학회 2008 디지털융복합연구 Vol.6 No.1

This paper is aimed to exam factors in the perceived service quality of web portal site and to analyze their effects on customer satisfaction. And this paper analysis satisfaction effects on revisit intention. To accomplish this purpose, this study examined previous studies and summarized core factors of service quality. Form literature survey, we drawn core factors. They are convenience, technologies, valuable of contents and service, communication, positioning. These core factors will affect on customer trust, satisfaction and satisfaction will affect on revisit intention. This study examined previous studies and summarized core factor in perceived service quality of web portal site. Fourteenth hypothesis were developed. Data for empirical testing were collected through survey to portal sites user. The results of this study are as follows; First, we find that service, communication and positioning have positive influence on the trust. Second, convenience, valuable of contents and postioning factors have a positive influence on the satisfaction. Third, it is shown that satisfaction have a positive influence on the revisit intention.

리눅스 실시간 스펙트럼 분석기를 이용한 컴퓨터 기반 순음청력검사 시스템의 자동 보정 지원

이승희,신범주,송복득,김진동,전계록,왕수건,Lee, Seung-Hee,Shin, Bum-Joo,Song, Bok-Deuk,Kim, Jin-Dong,Jeon, Gye-Rok,Wang, Soo-Geon 한국전기전자재료학회 2012 전기전자재료학회논문지 Vol.25 No.10

Compared to conventional pure-tone audiometer(PTA), the computerized one has several advantages such as relatively lower price, better flexibility, and easy operation. In addition, the computerized PTA can be easily extended to support automatic calibration. In this study, the support of automatic calibration in the computerized PTA has been addressed using the Linux realtime spectrum analyzer and network. In terms of accuracy, the new automatic calibration machine was compared to the existing manually operated one. According to the comparison, normal operation and high accuracy were observed within the scope of the international standard.

소형 다동체 레저낚시어선의 선형설계에 관한 연구

이승희,이영길,강대선,Lee, Seung-Hui,Lee, Yeong-Gil,Gang, Dae-Seon 선박안전기술공단 2004 선박안전 Vol.16 No.-

쌍동선이나 삼동선과 같은 다동체를 가진 선박의 선형과 유체 동력학적 특징들에 대하여는 실험과 동시에 수치적으로 널리 연구되어 왔다. 본 연구는 소형 다동체 레저낚시어선의 선형개발에 관한 연구로서 모형실험은 인하대학교 선형시험구조에서 수행되었으며 수치계산은 Euler 방정식의 유한차분해법이 이용되었다.