탈지분유 함유 식이를 섭취하는 흰쥐에서 칼슘과 비타민 D 수준이 무기질 대사에 미치는 영향

이경민,이연주,원은숙,이상선,Lee, Kyung-Min,Lee, Yeon Joo,Won, Eun-Sook,Lee, Sang Sun 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.4

The purpose of this study was to investigate the effect of calcium (Ca) and vitamin D (vit. D) levels on metabolism of various minerals such as Ca, P, Mg, Fe, Zn, Cu, and Cr. The comparison was made on the rats that were placed on diet containing powdered skim milk with different Ca and vit. D levels for 5 weeks. A total of 42 5-week-old Sprague-Dawley rats were divided into 7 groups as follows: Control group consisted of normal Ca and normal vit. D (0.5% Ca, 1,000 IU vit. D); Experimental groups were divided into low (0.25%) and high (1.0%) calcium levels; and vit. D group was divided into low (10 IU), normal (1,000 IU), and high (5,000 IU) subgroups. The weight gain and food efficiency ratios of the rats were not significantly different with increasing dietary Ca levels. The absorption rates of 7 minerals (Ca, P, Mg, Fe, Zn, Cu, and Cr) were significantly decreased with increasing dietary Ca levels. Also, fecal excretion of P significantly increased with increasing dietary vit. D levels (p<0.05), and urine excretion of Fe was significantly increased with increasing dietary vit. D levels (p<0.001). The result indicated that higher Ca intake affected on bioavailability of other minerals, due to interactions among minerals in the process of intestinal absorption. However, vitamin D intake had no effect on bioavailability of several minerals. Therefore, it could be suggested that adequate Ca intake is important for balance of the minerals.

위화(胃火) 1호(號)로 호전(好轉)된 만성위염(慢性胃炎) 환자(患者) 치험(治驗) 2례(例)

이경민,이세연,임성철,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Im, Sung-chul,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.6

Objective: This study was designed to investigate the effect of Wihwa herbal-acupuncture on chronic gastritis. Methods: Wihwa herbal-acupuncture was administered two times a week. The following points were selected: CV12(中脘), CV13(上脘), S36(足三里), Liv3(太衝). We checked pain rating score(P.R.S.), visual analogue scale (V.A.S.) and Gastroscopy. Results: After 6 weeks of treatment, the patient showed that clinical symtoms was disappeared, Lee's P.R.S. changed from 77 to 8 and Park's P.R.S. from 55 to 0 and gastric erosion disappeared on gastroscopy. Conclusions: These results suggest that and Wihwa herbal-acupuncture has good effect on chronic gastritis. But further studies are required to concretely prove the effectiveness of Wihwa herbal-acupuncture for treating chronic gastritis.

메쉬 직물의 밀도 및 위치변화에 따른 흡음특성

이경민,전두환,전상후,Lee, Kyoung Min,Chun, Du Hwan,Chun, Sang Hoo 한국섬유공학회 2015 한국섬유공학회지 Vol.52 No.3

Sound absorbing materials are generally categorized as porous-type absorbers and panel-type absorbers. In addition, their absorbing mechanism is typically described as a conversion of sound energy into heat energy through the dynamic behavior of the material. Thus one of the important parameters influencing the sound absorption characteristics is the density of the material. This study investigated the sound absorption characteristics of a mesh fabric based on the mesh density and fabric layering structure. Four different mesh densities (130, 180, 200, and 230 T) combined with five different layering structures were investigated to help understand the mechanism and effect of the sound absorption characteristics. The results indicate that a panel-type absorber has better sound absorption characteristics within a lower frequency range, whereas a porous-type absorber performs better at a higher frequency. In addition, the increased fabric density of the mesh fabric shows a better performance in terms of sound absorption. An empirical equation between the sound absorption coefficient and the fabric density was also derived for further design applications.

The possibility of low isomerization of β-lapachone in the human body

이경민,권미리,Hae Won Lee,성숙진,Young-Ran Yoon 대한임상약리학회 2021 Translational and Clinical Pharmacology Vol.29 No.3

β-Lapachone has been reported to have anticancer and various other therapeutic effects, but is limited in clinical applications by its low bioavailability. pH-Dependent isomerization can be suggested as one plausible factor influencing its low bioavailability. Since it is known that β-lapachone is converted to its isomer, α-lapachone in hydrochloric acid (HCl) solution, isomerization in the human body may be driven by HCl in the gastric fluid. The purpose of this study was to evaluate the possibility of isomerization of β-lapachone in the human body. Chemical reactions were conducted using simulated gastric fluid (SGF, pH 1.2) and simulated intestinal fluid (SIF, pH 7.5) at 37°C. β-Lapachone was observed in SGF at 37°C for 1 hour and SIF for 3 hours. In addition, biofluid analysis was performed on plasma samples 1 hour and 4 hours, and on urine sample 12 hours after oral administration of 100 mg MB12066, a synthetic β-lapachone, in healthy adult male. All samples were analyzed using liquid chromatography-tandem mass spectrometry. Only β-lapachone peaks existed in the spectra obtained from SGF and SIF. No isomerization of β-lapachone was observed in the analysis of any of the human samples. In the current study, the possibility of pH-dependent isomerization of β-lapachone in the human body was not confirmed.

엑시머레이저 굴절교정수술을 이용한 백내장 수술 후 잔여 난시에 의한 부등시의 교정

이경민,김은철,김만수,Kyung Min Lee,M,D,Eun Chul Kim,M,D,Man Soo Kim,M,D,Ph,D 대한안과학회 2008 대한안과학회지 Vol.49 No.10

Purpose: To evaluate the clinical effect of photorefractive keratectomy (PRK) and laser assisted in situ keratomileusis (LASIK) on eyes with anisometropia due to residual astigmatism after cataract surgery. Methods: We retrospectively reviewed the medical records of 11 eyes of 11 patients who had undergone cataract surgery from March 2002 to November 2005. PRK (2 eyes) and LASIK (9 eyes) was performed on 11 eyes with refractive myopic or mixed astigmatism over 1.5D after cataract surgery. Result: Before laser surgery, the mean astigmatism was 3.23±1.02D and the mean spherical equivalent (SE) was -2.27±1.43D. Six months after laser surgery, the mean SE was 0.66±0.58D and the mean astigmatism was 0.73±0.39D. The changes in mean manifest SE and astigmatism were statistically significant between paired preoperative and postoperative values (p<0.05). At 6 months after surgery, the mean uncorrected visual acuity and best corrected visual acuity significantly improved to 0.65±0.17 and 0.84±0.11, respectively. Three eyes (27.3%) developed mild haze and were treated without sequelae. There were no other complications. Conclusions: Excimer laser surgery appears to be a clinically useful procedure to correct residual astigmatism after cataract surgery. J Korean Ophthalmol Soc 2008;49(10):1589-1596

신경아교세포의 정상 기능과 정신장애에서 나타나는 신경아교세포 이상에 대한 고찰

이경민,Lee, Kyungmin 대한생물정신의학회 2015 생물정신의학 Vol.22 No.2

The brain maintains homeostasis and normal microenvironment through dynamic interactions of neurons and neuroglial cells to perform the proper information processing and normal cognitive functions. Recent post-mortem investigations and animal model studies demonstrated that the various brain areas such as cerebral cortex, hippocampus and amygdala have abnormalities in neuroglial numbers and functions in subjects with mental illnesses including schizophrenia, dementia and mood disorders like major depression and bipolar disorder. These findings highlight the putative role and involvement of neuroglial cells in mental disorders. Herein I discuss the physiological roles of neuroglial cells such as astrocytes, oligodendrocytes, and microglia in maintaining normal brain functions and their abnormalities in relation to mental disorders. Finally, all these findings could serve as a useful starting point for potential therapeutic concept and drug development to cure unnatural behaviors and abnormal cognitive functions observed in mental disorders.

도서관의 전자정보실 서비스 개선을 위한 이용사례 분석

이경민,Lee, Kyung-Min 한국도서관정보학회 2009 한국도서관정보학회지 Vol.40 No.4

국내 도서관은 정보화 시대에 적응하기 위하여 이용자에게 컴퓨터 사용환경을 일찍부터 제공하였다. 하지만 오늘날은 컴퓨터 사용환경이 일반화되어 전자정보실에 대한 변화가 필요한 시점이다. 이에 문헌정보학과 학생 78명으로 하여금 직접 전자정보실을 이용해 보게 하여 이용에 편리한 점과 불편했던 점을 기술하게 하였다. 이용사례 결과를 분석하여 전자정보실의 바람직한 변화 방향을 찾고자 하였다. 그 결과 사서에 의해 제공되는 정보서비스에서 불만이 가장 많았고, 그 이외에 시설과 장비 그리고 공간 순으로 많았다. 이를 개선하기 위한 방안으로는 도서관에서 전자정보실의 기능을 명확히 하는 미션과 서비스 방향을 정확히 제시하여야 하고, 사서는 전자정보실이 디지털 자료와 아날로그 자료 그리고 정보통신 기술지원이 동시에 제공되는 현대화된 레퍼런스 룸으로 인식해야 할 것이다. The domestic libraries offered users computer environment early to adapt in information age. However, the computer environment is generalized today, so it is needed to change about the role of electronic information room in this point. The author investigated use experience by 78 students who are student in library and information science. They experienced electronic information room and wrote their experience. As a result, they felt most inconvenience in information service of librarians, facilities and equipment and space. To improve the service of electronic information room, it is needed to develop the mission and service policy of electronic information room. And also the librarian must think the room as modern reference room that has digital and analog materials and information technology.

JPEG2000 CODEC을 위한 Entropy 코딩 알고리즘의 VLSI 설계

이경민,오경호,정일환,김영민,Lee, Kyoung-Min,Oh, Kyoung-Ho,Jung, Il-Hwan,Kim, Young-Min 한국통신학회 2004 韓國通信學會論文誌 Vol.29 No.1C

본 논문은 차세대 정지영상 압축방식인 JPEG2000 코덱의 엔트로피 코딩 알고리즘의 하드웨어적 구조를 제안하고, 설계하였다. 구현된 엔트로피 코더는 컨텍스트 기반의 산술부호화기로서 컨텍스트 추출부(CE)와 산술부호화기(AC)로 구성된다. CE는 각 코팅패스에서 코딩에 참여하지 않는 샘플은 skipping 함으로써 동작속도를 향상시켰으며, AC는 MQ coder에 기반을 둔 산술부호화기로서, 곱셈과 나눗셈 연산대신 단순 가감산과 shift 연산망을 이용하여 구조를 단순화하고 연산량을 줄임으로써 동작속도를 향상시켰다. 설계된 엔트로피 코더는 VHDL 모델링후 Xilinx FPGA technology를 이용하여 합성한 후 동작을 검증하였으며, 30MHz의 동작속도를 보인다. In this paper, we design an efficient VLSI architecture of entropy coding algorithm in JPEG2000. Entropy coder is a context-based binary arithmetic encoder, and composed of a Context Extractor(CE) and an Arithmetic Coder(AC). We speed-up CE by skipping no-operation bits in coding passes, and AC is to be performed based on MQ coder. Because of using Qe value associated with each allowed context and probability estimation, MQ coder is a multiplication free coder that reduces computation loads and makes simple the structure of arithmetic coder. We have developed and synthesized the VHDL models of CE and AC pairs using Xilinx FPGA technology. The proposed architecture operates up to 30MHz.

그리피스 컬렉션에 포함된 근대 인천과 한성 사진 연구

이경민,양상현,문병국,Lee, Kyeong-Min,Yang, Sang-Hyeon,Moon, Byeong-Kuk 한국건축역사학회 2015 건축역사연구 Vol.24 No.6

'Griffis Collection' is a collection of photographs of Japan and Korea in modern era, collected by William Elliot Griffis. Originally Mr. Griffis was studying about Japan when he developed an interest on Korea, and started to collect helpful materials he could find to study. Later days of Griffis' life, he donated his research to Rutgers University Library, and those materials were named and preserved as Griffis Collection. This paper is about photographs that illustrate modern Incheon and Hansung, and study them in order to discover how Korea's modern cities and architecture were formed and built. In total, there is four categorized chapters of photographs, and those are cities, public buildings, educational facilities and private buildings. In Griffis Collection, there are 23 photos those are relate to this paper's subject, but only 19 of them that has historic value has been covered in this paper. In results, all 19 photos were proved that they have significant information in terms of historic research of modern Korea and Korea's modern architectural stages.

자동차용 박강판 겹치기 이음부의 CO₂ 아크 용접에서 다중회귀분석기법을 이용한 용입깊이 예측에 대한 연구

이경민,심현우,권재형,윤북동,정민기,박문수,이보영,Lee, Kyung-Min,Sim, Hyun-Woo,Kwon, Jae-Hyung,Yoon, Buk-Dong,Jeong, Min-Ki,Park, Moon-Soo,Lee, Bo-Young 대한용접접합학회 2012 대한용접·접합학회지 Vol.30 No.2

Welding is an essential process in the automotive industry. Most welding processes that are used for auto body are spot welding and $CO_2$ welding are used in a small part. In production field, $CO_2$ welding process is decreased and spot welding process is increased due to welding quality is poor and defects are occurred in $CO_2$ welding process frequently. But $CO_2$ welding process should be used at robot interference parts and closed parts where spot welding couldn't. Because of the 0.65mm ~ 2.0mm thickness steel sheet were used in the automotive industry, poor quality of welding area such as burn through and under fill were happened frequently in $CO_2$ process. In this paper, we will study about the penetration depth which gives a huge impact on burn through changing a degree of base metal, welding position and torch angle. Voltage, current and welding speed were fixed but degree of base metal, welding position and torch angle were changed. And Cold- Rolled(CR) steel sheet was used. Penetration depth was analysed by multiple regression analysis to derive approximate calculations. And reliability of approximate calculations were confirmed through additional experiments. As the results of this research, we confirmed the effect of torch and plate angle to bead shape. And we present a possibility that can simulate more accurate to weld geometry, as deduced the verification equations that has tolerance of less than 21.69%.