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김영균,김수관,김경욱,엄인웅,Kim, Young-Kyun,Kim, Su-Gwan,Kim, Kyung-Wook,Um, In-Woong 대한악안면성형재건외과학회 2011 Maxillofacial Plastic Reconstructive Surgery Vol.33 No.3
An extraction socket was preserved and reconstructed using an autogenous tooth bone graft powder and block in two patients. The grafted site was healed 3 to 3.5 months after surgery. Implant treatment was successfully completed.
바다-$IV/I^2R$: 고차원 이미지 색인 구조를 이용한 효율적인 내용 기반 이미지 검색 시스템의 설계와 구현
김영균,이장선,이훈순,김완석,김명준,Kim, Yeong-Gyun,Lee, Jang-Seon,Lee, Hun-Sun,Kim, Wan-Seok,Kim, Myeong-Jun 한국정보처리학회 2000 정보처리학회논문지 Vol.7 No.2
A variety of multimedia applications require multimedia database management systems to manage multimedia data, such as text, image, and video, as well as t support content-based image or video retrieval. In this paper we design and implement a content-based image retrieval system, BADA-IV/I$^2$R(Image Information Retrieval), which is developed based on BADA-IV multimedia database management system. In this system image databases can be efficiently constructed and retrieved with the visual features, such as color, shape, and texture, of image. we extend SQL statements to define image query based on both annotations and visual features of image together. A high-dimensional index structure, called CIR-tree, is also employed in the system to provide an efficient access method to image databases. We show that BADA-IV/I$^2$R provides a flexible way to define query for image retrieval and retrieves image data fast and effectively: the effectiveness and performance of image retrieval are shown by BEP(Bull's Eye Performance) that is used to measure the retrieval effectiveness in MPEG-7 and comparing the performance of CIR-tree with those of X-tree and TV-tree, respectively.
의료용 표시기의 안전성 및 성능 평가를 위한 시험 항목 및 시험방법(안)연구
김영균,조승관,이태우,여창민,정병조,권영미,차지훈,허찬희,박기정,김동섭,김한성,Kim, Y.G.,Cho, S.K.,Lee, T.W.,Yeo, C.M.,Jung, B.J.,Kwon, Y.M.,Cha, J.H.,Hur, C.H.,Park, K.J.,Kim, D.S.,Kim, H.S. 대한의용생체공학회 2011 의공학회지 Vol.32 No.2
Tattooing is a performance for decorative and cosmetic marking by placing permanent ink into the skin. As the cultural meaning of tattoo in Korea is changing, the tattoo machines are widely spread n permanent cosmetic market. Though the use of the tattoo machine was increased, the evaluation standards of tattoo machine were not existed. Korea Food and Drug Association regulated the electrical and mechanical safety standards which were founded on the IEC 601-1 second edition. Also they regulated he biological safety standards which were derived from the ISO 10993 series, however, these general valuations of common medical device were insufficient for evaluating tattoo machine. We developed the standards of tattoo machine for safety and performance evaluation for tattoo machine by preliminary hazard analysis in ISO 14971. The evaluation criteria of tattoo machines are focused on the mechanical invasion. We suggested the additional evaluation items of the needle speed, length, vibration with general valuation criteria of common medical device. We anticipate that this research may be a primary stage to figure a standard regulation and evaluation for tattoo machine.
Mg+Al<sub>2</sub>Ca 첨가 ADC12 (Al-Si-Cu) 합금의 미세조직, 인장 및 고주기 피로 특성
김영균,김민종,김세광,윤영옥,이기안,Kim, Y.K.,Kim, M.J.,Kim, Shae K.,Yoon, Y.O.,Lee, K.A. 한국소성가공학회 2017 소성가공 : 한국소성가공학회지 Vol.26 No.5
This study investigated the microstructure, tensile strength, and high cycle fatigue properties of ADC12 aluminum alloys with different $Mg+Al_2Ca$ contents manufactured using die casting process. Microstructural observation identified the presence of ${\alpha}-Al$, eutectic Si, $Al_2Cu$, and Fe-intermetallic phases. The increase of $Mg+Al_2Ca$ content resulted in finer pore size and decreased pore distribution. Room temperature tensile strength tests were conducted at strain rate of $1{\times}10^{-3}/sec$. For 0.6%Mg ADC12, measured UTS, YS, and El were 305.2MPa, 157.0MPa, and 2.7%, respectively. For 0.8%Mg ADC12, measured UTS, YS, and El were 311.2 MPa, 159.4 MPa, and 2.4%, respectively. Therefore, 0.8% ADC12 alloy had higher strength and slightly decreased elongation compared to 0.6% Mg ADC12. High cycle fatigue tests revealed that 0.6% Mg ADC12 alloy had a fatigue limit of 150 MPa while 0.8% Mg ADC12 had a fatigue limit of 160MPa. It was confirmed that $Mg+Al_2Ca$ added ADC12 alloy achieved finer, spherical eutectic Si particles, and $Al_2Cu$ phases with greater mechanical and fatigue properties since size and distribution of pores and shrinkage cavities decreased as $Mg+Al_2Ca$ content increased.
고혈압(高血壓)의 원인(原因)에 관한 문헌적(文獻的) 고찰(考察)
김영균,권정남,박지은,김지웅,Kim, Young-Guen,Kwon, Jung-Nam,Park, Ji-Eun,Kim, Jee-Woong 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5
xWe studied about the causes of hypertension in the occidental and oriental medical records and the results are as follows. 1. The causes of hypertension in oriental medicine can be divided into wind, fire, phlegm and deficiency of Qi in our body, and broadly into three categories as emotions in excess, improper diet and damages of endogenous etiological factors. 2. Hypertension is the disease of undermining of fundamental aspects while prevailing incidental aspects and liver, heart and kidneys are the organs mainly related to hypertension. 3. The main pathological factors of hypertension are as follows; the disorder of Yin and Yang makes the situation of the deficiency of the vital essence of kidneys and the exuberance of the vital essence of liver and they are the fundamentals to be taken hypertension and finally make the state of the deficiency of both Yin and Yang. 4. In the point of occidental medical view, the essential hypertension is a disease of unknown etiology and we think it occurs not on the only one factor but on the various factors and secondary hypertension occurs from the diseases of the substances and the vessels of kidneys.
성향정기산(星香正氣散)이 가토의 경동맥(頸動脈) 평활근(平滑筋) 긴장(緊張) 및 $Ca^{2+}$ 대사(代謝)에 미치는 영향(影響)
김영균,권정남,김종훈,Kim, Young-Gyun,Kweon, Jung-Nam,Kim, Jong-Hoon 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.3
Objective : This study was undertaken to evaluate the effect of Sunghyangchungisan (SHCS) on the regulation of vascular tone and $Ca^{2+}$ metabolism in arterial tissues. Vascular rings isolated from rabbit carotid artery were myographed isometrically in isolated organ baths and the effect of SHCS on contractile activities, endothelial function and $Ca^{2+}$ metabolism were determined. Methods : In phentobarbital sodium-anesthetized rabbits, SHCS administered through ear vein (100 mg/Kg body wt.) or intragastric dwelling tube (300 mg/Kg body wt.) attenuated phenylephrine (PE, 10 ${\mu}g$/Kg, i.v.)-induced increases in both systolic and diastolic cartoid arterial blood pressure. Results : In experiments with isolated arterial strips, SHCS relaxed arterial rings which were pre-contracted by phenylephrine (PE, 1 ${\mu}M$). The responses to SHCS were partially dose-dependent at concentrations lower than 0.5 mg/ml. When SHCS was applied prior to the exposure to PE, it inhibited the PE-induced contraction by a similar magnitude which was comparable to the relaxation of pre-contracted arterial rings. Washout of SHCS after observing its relaxant effect resulted in a full recovery of PE-induced contractions, indicating that the action mechanism is reversible. The observation that SHCS did not change the $ED_{50)$ of PE oh its dose-response curve ruled out the possible interaction of SHCS with ${\alpha}$-receptors. The relaxant effect of SHCS was not affected by removal of endothelium or a nitric oxide synthase inhibitor, L-NAME. Methylene blue, an inhibitor of the soluble guanylate cyclase, did not affect the relaxant effect of SHCS. These results suggest that the action of SHCS is not mediated by the endothelium nor soluble guanylate cyclase. Constant cGMP production determined in arterial strips in the presence or absence of SHCS is consistent with this conclusion. When contraction was induced by additive application of $Ca^{2+}$ in arterial rings which were pre-depolarized by high $K^+$ in a $Ca^{2+}$-free solution, the relaxant effect of SHCS was attenuated by increasing the $Ca^{2+}$ concentration. SHCS, when applied to the arterial rings pre-contracted by PE and then relaxed by nifedipine, a $Ca^{2+}$ channel blocker, did not show additive relaxation. SHCS partially blocked $Ca^{2+}$ influx stimulated by PE and high $K^+$ which was determined by 5-min ^{45}Ca$ uptake, while it did not affect $Ca^{2+}$ efflux. Conclusions : From above results, it is suggested that SHCS relax PE-induced contraction of rabbit carotid artery in an endothelium independent manner, andinhibition of $Ca^{2+}$ influx may contribute to the underling mechanism.
Gd-Doped CeO<sub>2</sub> 분말의 마이크로파 소결
김영균,김석범,Kim, Young-Goun,Kim, Seuk-Buom 한국세라믹학회 2007 한국세라믹학회지 Vol.44 No.3
10 mol% $Gd_{2}O_{3}-CeO_{2}$ powder was sintered by microwave in a 2.45 GHz multimode cavity to develop a dense electrolyte layer for intermediate temperature solid oxide fuel cells (IT-SOFCs). Samples were sintered from $1100^{\circ}C$ upto $1500^{\circ}C$ by $50^{\circ}C$ difference and kept for 10 min and 30 min at the maximum temperature respectively. Theoretical density of the sample sintered at $1200^{\circ}C$ for 10 min was 95.4% and increased gradually upto 99% in the sample sintered at $1500^{\circ}C$ for 30 min. All of sintered samples showed very fine microstructures and the maximum average grain size of the sintered sample at $1500^{\circ}C$ for 30 min was $(0.87{\pm}0.42){\mu}m$. Ionic conductvity of the samples were measured by DC 4 probe method.
김영균,김종훈,Kim, Young-Gyun,Kim, Jong-Hoon 대한한의학회 1999 대한한의학회지 Vol.20 No.3
This study was undertaken to evaluate the effect of Sunghyangchungi-san (SHCS) on the oxidant-induced contraction and lipid peroxidation in rabbit carotid artery. Vascular rings isolated from rabbit carotid artery were exposed to t-butyl hydroperoxide (t-BHP), an extrinsic oxidant, and the effect of SHCS on the changes of vascular tension and lipid peroxidation induced by t-BHP was determined. t- BHP induced a slowly developing and sustained contraction of the arterial rings. SHCS effectively relaxed the arterial rings that were pre-contracted by t-BHP. The responses to SHCS were partially dose-dependent at concentrations lower than 0.5 mg/ml. When SHCS was applied prior to the exposure to t-BHP, it inhibited the t-BHP-induced contraction as well. t- BHP increased lipid peroxidation in a dose-dependent manner. SHCS as well as well-known anti-oxidants GSH and DPPD reduced significantly lipid peroxidation induced by t-BHP. SHCS partially blocked the increase in $^{45}Ca$ uptake induced by t-BHP. In contrast to SHCS, anti-oxidants GSH and DPPD failed to inhibit significantly the t- BHP-induced contraction or $^{45}Ca$ uptake. From the above results, it is suggested that SHCS relaxed t-BHP-induced contraction of rabbit carotid artery independently of its anti-oxidant action, and inhibition of $Ca^{2+}$ influx may contribute to the underlying mechanism.
소속명탕(小續命湯)이 백서(白鼠)의 국소뇌혈류량(局所腦血流量)과 혈압(血壓)에 미치는 영향(影響)
김영균,권정남,김경민,조은희,박지은,Kim, Young-Kyun,Kwon, Jung-Nam,Kim, Kyung-Min,Cho, Eun-Hee,Park, Ji-Eun 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5
SosokMyeongTang(SMT) have been used in oriental medicine for many centuries as a therapeutic agent for cerebral disease. The effects of SMT on the vascular system is not known. The purpose of this study was to investigate the effects of SMT on the changes in blood pressure(BP) and regional cerebral blood flow(rCBF) of rats. SMT consists of the following components : Radix Ledebouriellae(防風), Radix Cocculi or Stephaniae(防己), Semen Armeniacae(杏仁), Cortex Cinnamomi(肉桂), Radix Scutellariae(黃芩), Radix Paeoniae Lactiflorae(白芍藥), Radix Ginseng(人蔘), Rhizoma Cnidll(川芎), Herba Ephedrae(麻黃), Radix Glycyrrhizae(甘草), Radix Aconiti(附子?), Fructus Zizyphi Jujubae(大棗), Rhizoma Zingiberis(生薑) and the changes of BP and rCBF were tested Leser-Doppler Flowmetry(LDF) The experimental results were as follows ; BP was not affected by SMT in rats, but rCBF was increased significantly by SMT in a dose dependent manner. SMT increased previous decreasd rCBF due to pretreatment methylene blue, but did not increased previous decreasd rCBF due to pretreatment L-NNA, indomethacin. Pretreatment with indomethacin decreased BP compaired with control group. These results suggest that SMT causes a diverse response of blood pressure and regional cerebral blood flow(rCBF). The increased rCBF is mediated by nitric oxide synthease.