Ho-166 부착풍선도자를 이용한 방사선 조사의 돼지 관상동맥 스텐트 재협착 예방 효과

김원 ( Kim Won ),정명호 ( Jeong Myeong Ho ),박옥영 ( Park Og Yeong ),정우곤 ( Jeong U Gon ),박우석 ( Park U Seog ),김주한 ( Kim Ju Han ),안영근 ( An Yeong Geun ),조정관 ( Jo Jeong Gwan ),박종춘 ( Park Jong Chun ),강정채 ( Kang Je 한국지질동맥경화학회 ( 구 한국지질학회 ) 2002 韓國脂質學會誌 Vol.12 No.1

배경 : 국내에서 개발된 방사선 동위원소 Holmium-166 (166Ho)은 주로 베타선을 방출하며, 166Ho을 부착한 풍선도자를 이용하여 돼지 관상동맥 재협착 모형에서 풍선확장술 후 신생내막 증식을 전신적 부작용 없이 안전하고 효과적으로 억제하였음을 보고한 바 있다. 본 연구에서는 돼지 관상동맥 스텐트 재협착 모형에서 스텐트 시술 후 신생내막 증식에 의한 재협착 병변을 166Ho 부착 풍선도자를 이용하여 치료하여 그 효과를 관찰하고자 하였다. 방법

8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

불규칙 반복하중을 받는 무근콘크리트의 누가손상

강호영,김영진,변근주,이기성 연세대학교 산업기술연구소 1988 논문집 Vol.20 No.1

An assessment of cumulative damage of plain concrete subjected to random loading is studied in this paper. Random loading of Beta distribution, which is governed by the mean and standard deviation of peak stresses working on concrete, is applied and the influence of the random loading on the fatigue of plain concrete is analyzed. The relationship among mean of peak stresses, its standard deviaton and fatigue life, the relation between fatigue life and changes in strain, and the one between fatigue life and modified Palmgren-Miner hypothesis are investigated for the random compressive loading on concrete cylinder specimens. From these relationships, a model which may be used to estimate the cumulative damage of concrete structure subjected to random loading of Beta distribution is proposed.

杜甫〈北征〉考

姜旼昊,李永朱 한국중국어문학회 2000 中國文學 Vol.34 No.-

<北征>爲杜詩巨篇之一, 凡七百字, 一百四十句. 全篇以敍事爲主, 雜以議論, 其表現手法及詩題命意, 管源於賦鑑, 可謂爲變賦入詩者, 其敍事又以紀行爲主, 亦可調爲韻賦爲詩者. 其作法如此, 前所未見, 赤當時諸家所不及, 爲後來古文家惑宋詩人以文代詩者, 先示其指南. 玆篇中結合相反之諸因素, 自內容方面而觀, 則有軍國大事與個人私情之默照, 自形式方面而觀, 則有古體與長律之融化. 因沈, 車法幻妙, 忽正忽反, 若整若亂, 時斷時績, 其渡欄壯闊處, 極長篇車法之法數, 撤去舊來藩籬, 接大詩家之新地平. 玆篇作於唐肅宗至德二載, 其年五月, 杜甫拜左拾遺, 소救房琯以觸皇帝怒, 幸而得知人之救以免大禍. 其年八月墨動放還부州而省妻予, 名是臨時停職而省家, 賓則無異於罷職而歸家. 誠心忠君, 身接棄擲, 欲隙時政, 已無言路, 北征途中, 自有心中葛藤. 籍中種種相反因素之共存, 實由於其薄藤之反映耳.

사람주나무잎의 페놀성 성분

안영진,이승호,강신정,황방연,박웅양,안병태,노재섭,이경순 영남대학교 약품개발연구소 1996 영남대학교 약품개발연구소 연구업적집 Vol.6 No.-

A chemical examination of the phenolic compounds in the leaves of Sapium japonicum (Euphorbiaceae) has led to the isolation of eleven phenolic compounds. containing five hydrolysable tannins and six flavonoids. On the basis of chemical and spectroscopic evidences, the structures of these compounds were confirmed to be galic acid(1), 5-O-caffeoyl quinic acid(2), 1-O-galloyl-3, 6-(R)-HHDP-β-n-glucose(coriiagin)(3), 1-O-galloyl-2.4-(R)-DHHDP-βn-glucose (furosin)(4), 1-O-galloyl-2.4-(R)-DHHDP-3.6-(R)-HHDP-β-m-glucose(geraniin)(5), astragalin(6), trifolin(7), afzelin(8), quercetin(9), isoquercitrin(10) and rutin(11). Among them geraniin was the main component.

한국 성인의 경추부 추간판 높이와 깊이에 대한 연구

이상호,장의성,정승은,신송우,강호영 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

Objective: Currently, normal data of cervical disc height and depth of Korean adults are not available. The objective of this study is to compile a Korean normative database of the disc height and depth of the cervical spine, valid for healthy Korean adults. Methods: All the volunteers were attached a coin on the anterior midline of the neck. From the lateral X-ray films of the cervical spine, anterior and middle disc height and anteroposterior disc depth from C2-3 to C6-7 were measured. The magnification of radiographic films as compared with real measurement of the coin was taken into consideration. Analysis of data was done by use of independent sample t-test, Pearson's correlation, and one-way analysis of variance(ANOVA). Results; A normal database for the dimensions of cervical discs was compiled from 42 lateral views of healthy Korean adults. There were 20 males(mean age, 29,6 years; mean height, 174.3 cm) and 22 females(mean age, 27,4 years; mean height, 161.2 cm). The means of anterior height, middle height and anteroposterlor depth of cervical disc space were 4.09mm, 5,82mm, and 16,86mm for men and 3,40 mm, 5.30 mm, and 14.86 mm for women, respectively, The height of C4-5 disc space was highest at the middle disc space from C2-3 to C6-7. Conclusion: This study will contribute to the clinical diagnosis, treatment and development of instruments of cervical disc diseases for Korean patients with cervical disc diseases.

새조개 처리동결 가공부산물을 이용한 페이스트 젓갈의 품질 및 저장안정성

손정호,강훈이,김명희,하정자,강동수,조영철 여수대학교 1997 論文集 Vol.11 No.2

A fermented squeezed-type paste was manufactured for the purpose of effective utilization of cockle shell by-product, and their rheological properties, texture and storage stability were investigated. The contents of moisture, portein, lipid, carbohydrate and ash in the fermented product were 57.7%, 3.2%, 2.4%, 17.6% and 19.3%, respetively. When storage at 90 days, the contents of chemical composition were little changed. During the storage period, pH and salinity were 6.3~6.6 and 20.3~20.65%. And the product was stable for the storage of 60 days at 23±3℃ on bacterial growth. The major free amino acid in the product were glutamic acid, lysine, leucine, valine and aspartic acid. And during the storage period, orders and contents of amino acid composition were not changed compared with 0 day storage. Thus, fermented squeeze-type cockle shell by-product paste were stable that decomposition was not continued at storage period.

치과주조용 Ti-Zr-Cr계 합금에서 Cr 함량변화가 부식저항성에 미치는 영향

박영준,강후원,이용렬,송호준,김민강 大韓齒科器材學會 2004 대한치과재료학회지 Vol.31 No.4

The purpose of this study was to develop new dental casting titanium (Ti) alloys having an excellent mechanical properties and good corrosion resistance as a substitute for c.p Ti and Ti-6Al-4V alloy (control groups). Ti-20Cr, Ti-2OZr and Ti-20Zr-XCr (X=2, 5, 10, 15) alloys (experimental groups) were designed for dental casting Ti alloys. Prior to casting prccedure, mother alloys were prepared by using vacuum arc melting with skull melting method. Argon-arc melting and argon/vacuum-pressure casting machine were used for making the specimens. The hardness, microstructure, and corrosion resistance were evaluated by using Vickers microhardness measurement, FE-SEM, and anodic polarization test. The results were as follows: 1. The Vickers microhardness (Hv) of Ti and Ti-6Al-4V alloy showed the values of 210 and 352, and Ti-20Cr and Ti-20Zr alloys showed the values of 341 and 259, respectively. As the Cr content increased from 0 to 15 % in Ti-20Zr-XCr (X=0, 2, 5, 10, 15) alloys, the Hv increased from 259 to 298, 457, 344, and 351, respectively. The microstructure of Ti-20Zr-XCr specimens showed significant difference by the concentration changes of Cr content showing acicular crystalline structure for Ti-20Zr-2Cr and Ti-20Zr-5Cr, and equiaxed crystalline structure for Ti-20Zr-10Cr and Ti-20Zr-15Cr. 2. Open-circuit potentials (E_(∝)) were rapidly decreased followed by steadiness as time elapse in all experimental groups except in Ti-20Z group. Ti-2OZr group showed an increase in E_(∝), from the first. 3. In potentiodynamic anodic polarization tests, all experimental groups showed more noble corrosion potential (E_(corr) than that of Ti-6Al-4V, and more basic E_(corr) than that of Ti. Especially, Ti-20Zr-10Cr alloy showed most favorable corrosion resistance among Ti-Zr-Cr alloys. 4. For Ti-20Zr-10Cr, Ti-20Zr-15Cr, and Ti-20Cr groups, which have more than 10% Cr content, the secondary corrosion potential shifted to noble direction in larger amounts than in the cases of control and other experimental groups. From these results, it was concluded that newly formulated Ti-20Zr-10Cr experimental alloy have adequate hardness and high corrosion resistance, and this alloy is promising candidate for a successful dental casting alloy.

한국형 후각검사 KVSS Test의 개발

홍석찬,유영석,김은서,김석천,박수홍,김진국,강성호 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구

백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.