서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

구매단가 및 운송비 할인을 고려한 최적 주문 정책

김재균,신성환 울산대학교 1991 공학연구논문집 Vol.22 No.2

본 논문은 구입량에 따라 구매 가격과 운송비용이 각각 할인되는 상황하에서 주문 정책을 수립할 때 총비용을 최소화시키는 적절한 주문량을 결정하는데 그 목적이 있다. 본 고에서는 구매 단가의 경우에는 단계할인이 적용되고 운송비용의 경우에는 운송단위별로 할인이 이루어지는 경우에 대한 모델이 제시되었으며 이와같은 할인 계획하에서 최적 주문량을 결정할 수 있는 절차가 제시되었다. This paper deals with an EOQ model in which both the unit purchasing price and the freight cost depend on the quantity of the lot size. The model adopts incremental quantity discounts for the price and a general form of discounts for the freight cost. Investigation of the properties of an optimal solution allows us to develop an algorithm whose validity is illustrated through an example problem.

Silver Nitrate溶液의 精巢內 注射에 衣한 家兎의 去勢效果에 關한 硏究

金鐘洙,趙聖均,李殷奉 順天大學校 1984 論文集 Vol.3 No.1

This experiment was carried out to develop a Chemical castration with a single intratesticular injection of silver nitrate solution in domestic rabbits. A total of 44 bucks of 4 to 5 months old were alloted at random into the following 4 groups; 9 bucks for controls; 6 bucks for 0.3㎖ injection of 1% AgNO₃to each testis; 14 bucks for 0.5㎖ injection of 1% AgNO₃: and 15 bucks for 0.5㎖ injection of 5% AgNO₃. Changes in body weight, testicuar width in scrotum sac, weight and histology of testis at slaughter, blood cell counts and serum levels of testosterone of the buck were measured for 4 weeks after treatment. The results obtained were summarized as follows: 1. Compared with the controls the body weght gain of bucks treated with AgNO₃was not significantly (P<0.05) different during the experimental period for 4 weeks. 2. The white blood cell counts were increased slightly but insignificantly 1 day after injection of AgNO₃and then decreased to normal level soon. There was no significant change in red blood cell counts in the bucks treated with AgNO₃. 3. Most of the testis of bucks were swollen significantly (P<0.05) by 6 to 12㎜ in the width of testis in scrotum sac 1 day after injection of AgNO₃, but decreased in size 3 days after treatment and regained their normal size in a week. 4. The AgNO₃injection was not sufficient for same bucks to be successfully castrated. Only 60.0 to 66.7% of the bucks treated with 0.5㎖ dose of 1 to 5% AgNO₃showed the serum level of testosterone of lower than 0.1ng/㎖ by 28 days after treatment. This was considered to be resulted from the fact that not a whole but a limited part of testis injured by this scheme of injection. 5. The weight of testis of the bucks showing less than 0.1ng/㎖ of serum testosterone by 7 to 28 days after treatment was not significantly (p<0.05) different between the treatments of periods after treatment. This result indicates that the period of 4 weeks might be not sufficient for the injured testicular tissue to be necrotized and absorbed. 6. The extent of damage of testis by injection of AgNO₃was much different by the local effect in the parts of distance from injection. A proximal portion of testis injected with AgNO₃was fully damaged and necrotized, but a distal part of testis was not severely damaged.

유기용매 추출법과 산가수분해에 의한 포플라의 전처리 및 효소당화액을 이용한 생물고분자의 생산에 관한 연구

김균성,박정극 동국대학교 산업기술대학원 1993 산업기술논문집 Vol.1 No.-

In this study the lignocellulosic biomass, Italy poplar, was pretreated by the chemical pretreatment method, i.e., organic solvent (Phenol/H_2O) extraction. Using Phenol/H_2O solvent system. Wood yield, % delignification and % sacchari-fication(72hours) of poplar after pretreatment at 190℃, 60 min. which was found out as the optimum pretreatment condition, were 46,3%, 96.1% and 83.35% (43.87 g/L) respectively. The possibility of reusing the spent organic solvent and recovery of hemicellulose fraction were also studied. By recycling spent black organic solvent in this process, we obtained an approximately identical results. The percent saccharification of 79.9% (43.6 g/L) was obtained from the recycled process and the degree of delignification was more than 99%. The delignification reactions using Phenol/H_2O solvent system showed two distinct mechanism of pseudo first order reactions (fast and slow), and the activation energy of the fast reaction was 38.4Kcal/gmol. For the recovery of hemicellulose fraction, poplar wood was pretreated using acid as a catalyst at high temperature and low concentration;180℃,0.05%∼0.15 vol% H_2SO_4(HTLC), and also at low temperature and high concentration;120℃,1∼4 vol% H_2SO_4(LTHC). 58% of hemicellulose was recovered whin the Italy poplar was pretreated at 180℃ with 0.1 vol% H_2SO_4 for 10 minutes (HTLC), and 74.4% recovery of hemicellulose fraction was obtained when it was pretreated at 120℃ with 4 vol% H_2SO_4 (LTHC) for 20 minutes, which is considered as an optimum condition for hemicellulose recovery. And after these acid hydrolysis followed by solvent extraction at 190℃, 60 min, the lower amount of sugar was obtained compared to one-step solvent extraction which was studied. As an application of saccharified broth, the culture of Zoogloea remigera 115 which produces biopolymer adsorbing heavy metals (Cu, Fe, Zn, Co etc) was conducted. When saccharified broth was used as a carbon source, the lag phase of the fermantation was longer than that of synthetic glucose media. After 60 hours of fermentation, the maximum cell density of 1.5 g/L was obtained. Final biopolymer concentration was 10.05 g/L after 200 hours of fermentation. Above experimental results showed the possibility of using saccharified broth as a carbon sourse for fermentation media.

인화성물질 검출 시험법 정립에 관한 연구

김은호,신윤열,김명덕,김재균,장성길 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

연속회분식 반응조를 이용한 슬러지 소화에서 포기비율과 포기빈도가 슬러지 소화에 미치는 영향

김성홍,김희준,최영균,정태학 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

Lab-scale sequencing batch experiments were carried out to investigate the effects of aeration ratio and aeration interval on nitrogen and phosphorus transformation during the sludge digestion by intermittent aeration. The highest nitrification and denitrification efficiency could be obtained when the aeration ratio was 0.25. Nitrification inhibition caused by alkalinity deficit was not observed at the aeration ratio of 0.75, however denitrification was limited at this level of aeration ratio. Biological phosphorus accumulation was possible at the aeration ratio of 0.25, however it was not observed when the aeration ratio was over 0.5. Under the same condition of aeration ratio, aeration interval played an important role in phosphorus release. Soluble phosphorus concentration of digested sludge was about 1.5㎎/L when the aeration interval was 4 hr and that was much lower than the concentration (12-18㎎/L) when the aeration interval was 20-44 hrs.

하수의 유기물 분류에 미치는 동력학적 영향인자의 민감도 분석

최영균,김성홍,정태학 대한상하수도학회 2003 상하수도학회지 Vol.17 No.3

The effects of 6 kinetic parameters such as Y_H (yield coefficient of heterotrophs), b_H (decay rate of heterotrophs, /d), μ_HR (heterotrophic maximum specific growth rate on RBCOD, /d), μ_HS (heterotrophic maximum specific growth rate on SBCOD, /d), K_S (heterotrophic half saturation coefficient for RBCOD, ㎎COD/L) and K_X (heterotrophic half saturation coefficient for SBCOD) on the variation of RBCOD (readily biodegradable COD) concentration were analyzed during the COD fractionation of primary settled municipal wastewater by simulation of respirometric tests. Variation of RBCOD concentration was the highest when Y_H was changed within the acceptable range and standard deviation was about 48% of the averaged RBCOD concentration. Standard deviations of RBCOD concentration were about 10.4 and 6.3% of the averaged values when μ_HS and K_X were changed, respectively and it was about 6.5% when b_H was changed. The effects of μ_HR and K_S on RBCOD estimation were lower than the other kinetic parameters and the variations of RBCOD concentration were only about 2.2 and 3.5% of the averaged value when those two kinetic parameters were changed, respectively. Accordingly, hydrolysis or oxidation of SBCOD (slowly biodegradable COD) was more important than RBCOD oxidation during the analysis of respirometric test. It means that the variation of RBCOD concentration was more sensitive to the change of μ_HS and K_X than that of μ_HR and K_S because μ_HR and K_S did not directly affect the RBCOD concentration in wastewater. However, μ_HS and K_X could affect the RBCOD concentration through hydrolysis of SBCOD.

프로그람의 최적화 기법에 관한 연구

이용석,김기철,오성균 全北大學校 基礎科學硏究所 1986 基礎科學 Vol.9 No.1

In this paper, we briefly discuss a number of machine-independent optimizations, program transformations that can be performed on programs to increase the efficiency of the target code without taking into considerration any properties of the target machine.

설계환경을 위한 트랜젝션의 관리에 관한 연구

강현석,김기철,오성균 全北大學校 基礎科學硏究所 1986 基礎科學 Vol.9 No.1

For implementing to design data management in CAD environment, the design transaction must be managed effectively. In this paper, we compared the most known two techniques about this issue. And also we described a design transaction management which is adapted to our proposed design object management system.[8]

카드뮴 측적량과 붕어(Carassius auratus) 아가미 조직 변화의 상관성에 관한 연구

배희경,김은경,남성숙,문창규,전성환,나진균,박광식 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

Histopathological changes and cadmium accumulations in the gills were investigated in crucian carp (Carassius auratus) exposed to 0, 0.01, 0.1, 0.5 mg/l cadmium (Cd)concentrations for 25 days. After 25 days of exposure, cadmium accumulations increased in each of the different exposure concentrations. Histopathological changes in the gills of curcian carp exposed to cadmium included the acidification of mucous cell, the terminal clubbing of lamellae, the hyperplasia of epitherial cell and the curved of secondary lamellae. The similar histopathological changes were observed once the accumulations of cadmium reached the similar levels found in the present study with the different exposure schemes. Also the acidification of mucous cell in gills appeared when cadmium accumulations reached 5 ㎍/g and more. These results suggested that histopathological changes in the gills, an appearance of mucous cell acidification, be used to estimate the relation between toxic effect and cadmium accumulations in the gills.