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고압멸균 처리시간에 따른 닭 체내 조류인플루엔자와 뉴캐슬병 바이러스의 멸균효과
이진주 ( Jin Ju Lee ),김동혁 ( Dong Hyeok Kim ),임정주 ( Jeong Ju Lim ),김대근 ( Dae Geun Kim ),민원기 ( Won Gi Min ),이후장 ( Hu Jang Lee ),장홍희 ( Hong Hee Chang ),김석 ( Suk Kim ) 한국예방수의학회(구 한국수의공중보건학회) 2011 예방수의학회지 Vol.35 No.4
Avian influenza (AI) and Newcastle disease (ND) distress a variety of avian species, especially domestic poultry. Severe syndromes are caused by highly virulent specific virus strains termed highly pathogenic AI and velogenic ND viruses, which are potential agrobioterrorism agents. This outbreak emphasizes the need for continuing cooperation between public health and veterinary medical communities in controlling AI and ND when it has a zoonotic potential. Up to date, the stamping out and burying system were applied for controlling methods against these highly infectious diseases in the ordinary way, however these methods had many environmental problems, including leachat and effluvium. Thus, we assessed that sterilization effect of AI and ND virus dependent on several treatment conditions, such as autoclaving time and cutting types of chicken. As a result, we found that the cutting type of chicken meat revealed a reduced HA titer (20) against both of AI and ND virus after 10 min of autoclaving, while whole chicken showed same titer after 30 and 60 min. Therefore, we propose that the conditions of treatment on infected chicken should be developed for convenient, affordable, and effective prevention methods against for AI and ND.
냉동 건조 탈회 동종골 이식후 골막이 골 형성 과정에 미치는 영향에 관한 실험적 연구
이동근,엄인웅,민승기,권혁도 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.4
Periosteum in general is described as a specialized fibrous membrane of mesenchymal origin consisting of two basis layers : outer fibrous layer consists of irregularly arranged dense connective-tissue with fibroblasts, and inner osteogenic or cambial layer is composed of more loosely arranged fibers, greater vascularity and flatted spindle-shaped pre-osteoblasts. This periosteum may serve in controlling bone growth, especially mandibular growth has been emphasized. But, the periosteum enwrapping the facial skeleton have been studied for many years leaving a controversy in opinion regarding the function of these structures. We evaluated the bone formation activity of te periosteum in allogeneic bone grafts which bones are made of freeze-dried preparation preoperatively. We made the calvarial bone defects, 5×7mm sized, amd grafted with allogeneic bone in rats, which a half of specimens has dissected the overlying periosteum and a rest intacted. After bone grafting, we evaluated the capacity ofbone formation of periosteum, 1, 2, 4, 6, 8 weeks postoperatively. There are subtle differences of bone formation during early healing period after demineralized allogeneic bone grafting between control groups with periosteum and experimental groups without periosteum.
전립선암과 전립선비대증 환자에서 혈청 유리 및 총전립선특이항원 측정의 의의
서혁준,박형민,권태균,정성광,김법완,이재태 경북대학교 의학연구소 2000 경북대학교병원의학연구소논문집 Vol.4 No.1
Purpose: This study was peformed to investigate whether the free to total PSA ratio(F/T PSA ratio) offers a better discriminant for the detection of patient with prostatic cancer(CaP) and those with benign prostatic hyperplasia(BPH) than serum total PSA alone. Materials and Methods: From September 1996 to February 1999, free and total PSA levels were measured on frozen sera samples of 154 men with BPH and 46 with CaP using immunoradiometric assay. Results: In all subjects, the mean total PSA was significantly higher in CaP group(72.57±66.58ng/ml) than BPH group(3.12±4.10ng/ml). The mean PSAD was significantly higher in CaP group(1.64± 1.86) than BPH group(0.08±0.01). The mean F/T PSA ratio was significantly lower in CaP group(0.19± 0.07) than BPH group(0.30±0.13). Among 41 subjects whose total PSA were between 4-20ng/ml, the mean PSAD was significantly higher in CaP group(0.37±7.16) than BPH group(0.17± 0.07), but the mean F/T PSA ratio was not significantly different between CaP(0.19± 0.10) and BPH group(0.25±7.13). By comparing the sensitivity and specificity of total PSA alone, PSAD and F/T PSA ratio on receiver operating characterislic (ROC) Cutie in all subiects and subiects with total PSA between 4-20ng/ml, F/T PSA ratio had no superiority than total PSA alone and PSAD for discrimination between CaP and BPH. Conclusions: We suggest that the F/T PSA ratio is not superior to total PSA alone and FSAD in the detection of prostatic cancer, and further evaluation of the usefulness of F/T PSA ratio should be required.
김의영,임승혁,이재학,강민철 龍仁大學校 武道硏究所 2004 武道硏究所誌 Vol.14 No.2
The purpose of this study was to determine the relationship of demographic characteristics to job stress among security guards. The subjects in this study were 474 people selected by random cluster sampling from a population that consisted of private bodyguards and security guards from Seoul, Gyeonggi province and Daejeon. They gave a faithful response when a survey was conducted, and incomplete answer sheets from the others of the population were excluded. For data analysis, SPSS/PC Windows V11.0 program was utilized, and frequency analysis, t-test, one-way ANOVA and Scheffe posttest were employed. The findings of this study were as follows: First, the gender of the security guards investigated made a significant difference to their job satisfaction(p<.05). Job characteristics, compensation and organizational characteristics put higher strain on the men than on the women, and the latter group was more stressed out about their roles and interpersonal relations. Second, their age, education, years of services and monthly income made a significant difference to their job stress subvariables related to job characteristics, roles, human relations, compensation and organizational characteristics(p<01). Third, their job stress was significantly different according to their position and status(p<01). Specifically, those who had no position were under heavier pressure due to job characteristics, roles, interpersonal relations, compensation and organizational characteristics.
Ki-Kang Kim,Soo-Min Kim,Yan Cui,Mun-Seok Jeong,Jong-Hun Han,Young-Chul Choi,Kay-Hyeok An,Kyung-Hui Oh,Young-Hee Lee 한국탄소학회 2009 Carbon Letters Vol.10 No.1
We measured the degree of macrodispersion of the various single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) using UV-VIS-NIR absorption spectroscopy. CNTs were dispersed with SDS of 2 wt % in deionized water using the homogenizer and then were further centrifugated at 6000 g for 10 min. The degree of macrodispersion, expressed by Dm(λ)=Aa(λ)/Ab(λ)*100 (%), where λ is the wavelength and Aa(λ) and Ab(λ) are the absorbance of the sample after and before centrifugation, respectively. In the case of MWCNTs, we evaluated the degree of macrodispersion by the average degree of macrodispersion (Dm(λ)) between 1000 and 1200 nm. The degree of macrodispersion of SWCNTs was evaluated at the wavelength in which van Hove singularity-related transition regions were excluded, i.e., the range was chosen between E11S and E22S peaks. We have estimated six samples with the same method. The standard deviation of each sample was lower than 5. Therefore, we presented a reliable evaluation method for the macrodispersion of CNTs for standardization.
Lee, Hyungsoo,Choi, Jin Hyeok,Jo, Min Chul,Lee, Donghyun,Shin, Sangmin,Jo, Ilguk,Lee, Sang-Kwan,Lee, Sunghak Elsevier 2018 Materials science & engineering. properties, micro Vol.738 No.-
<P><B>Abstract</B></P> <P>Quasi-static and dynamic compressive properties of 7075-T6 Al matrix composites reinforced with SiC<SUB>p</SUB>s (size; 10 µm, 30 µm, and bimodal (10 + 30) μm), <I>i.e</I>., 10S, 30S, and BS composites, respectively, were investigated in relation with fracture mechanisms. SiC<SUB>p</SUB>s were homogeneously distributed without SiC<SUB>p</SUB> agglomeration, pores, or cracks, and their volume fractions were 49.5 vol%, 54.1 vol%, and 56.5 vol% in the 30S, 10S, and BS specimens, respectively. Compressive properties could be explained by a rule of mixtures based on SiC<SUB>p</SUB> volume fraction and by three major fracture phenomena including deformation of Al matrix, cracking of SiC<SUB>p</SUB>s, and interfacial debonding between SiC<SUB>p</SUB> and Al. As the SiC<SUB>p</SUB> size decreased, crack initiation sites changed from SiC<SUB>p</SUB>s themselves to SiC<SUB>p</SUB>/Al interfaces, which mainly affected the compressive strength. In the BS composite, coarse SiC<SUB>p</SUB>s additionally worked for the strengthening by increasing the total reinforcement fraction, and the three fracture phenomena were well homogenized, thereby leading to the highest strain energy density as well as the best combination of strength and strain.</P>
Down-regulation of RUNX3 induced by Helicobacter pylori in mouse splenocyte
( Min Won Baek ),( Seung Hyeok Seok ),( Hui Young Lee ),( Dong Jae Kim ),( Yi Rang Na ),( Sung Hun Park ),( Hyun Kyoung Lee ),( Dutta Noton Kumar ),( Byoung Hee Lee ),( Jae Hak Park ) 한국동물실험대체법학회 2007 한국동물실험대체법학회 학술대회집 Vol.2007 No.1
RUNX3 is necessary for the suppression of cell proliferation and apoptosis of the gastric epithelium, quantitative neurogenesis of the dorsal root ganglia, and differentiation of T & B-cell. Because of its tumor suppressor ability, RUNX3 is the target gene of cancer diagnosis and therapeutic approach. Helicobacter pylori is well known carcinogen for gastric cancer and MALT lymphoma Therefore, the direct induction of RUNX3 decrease by H. pylori was investigated here using mouse splenocyte. During 2 days of incubation with bacterial lysate a dose-dependent and time-dependant decrease of RUNX3 mRNA and protein was found, which was followed by RUNX3 P2 promoter region hypermethylation detected by methylation specific PCR and was not observed after treatment with Escherichia coli lysate (control). This decrease of RUNX3 mRNA and protein may be a link between H. pylori infection and development of gastric adenocarcinoma and MALT lymphoma.