부산 영도(절영도), 신라왕실목장

서영교 ( Seo Young-kyo ) 부산광역시사편찬위원회 2017 항도부산 Vol.33 No.-

The Han Chinese were also strongly attracted by the tall and powerful horses (heavenly horses) in the possession of the Dayuan(大宛) According to the Shiji(『史記』), grapes and alfalfa(??) were introduced to China from Dayuan following Zhang Qian`s embassy: The Dayuan people love their wine and the horses love their alfalfa. The Han envoys brought back grape and alfalfa seeds to China and the emperor for the first time tried growing these plants in areas of rich soil. Later, when the Han acquired large numbers of the heavenly horses and the envoys from foreign states began to arrive with their retinues, the lands on all sides of the emperor`s summer palaces and pleasure towers were planted with grapes and alfalfa for as far as the eye could see. Even in the Tang era heavenly horses is popular in China. Poets are constantly praised heavenly horses at the end. The horse was introduced into Silla, and alfalfa seeds to here. Alfalfa was grown from four ranches in the Silla capital. Pusan Young-do Island where the Silla Royal Family Ranch feed heavenly horses. The horses are carried on the capital. The King Seongdeok gift the horses to the Grand son of Kim Yu-shin. A lot of jealousy over the Case of the royal family who had a many pony horse. The horse was tall horse that they are not owned. The Silla Royal Family ranch is in the 10th century maintains a reputation. The Second Beakje King Jin-won gift the heavenly horses that produced there to Korea King Wang-keon. The king Jin-won has had a change mind it back. About here is constantly by songs in future generations.

그레이브스 병 치료 후 재발 위험 인자에 관한 연구

이영창,유명희,윤석기,변동원,서교일,김극배 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

연구 배경 : 그레이브스 병에 대한 항갑상선제 치료후 적절한 치료 여부 평가 및 재발 위험성을 예측하기 위하여 여러 가지 예후 판정 인자들이 연구되어 왔으며, 이러한 인자들 중 TRH(thyrotropin-releasing hormone) 자극 시험이 가장 믿을 만한 검사중에 하나로 알려져 있다. 그러나 TRH 자극 검사가 정상으로 나와도 재발하는 경우가 많으며, 현재로는 이러한 경우에 재발을 예측하는 예후 인자에 대한 연구는 전무한 실정이다. 금번 연구에서는 TRH 자극 시험 후 TSH(thyroid stimulating hormone)가 정상적인 반응을 보인 환자를 대상으로 재발 및 관해여부를 예측할 수 있는 인자들을 찾고자 하였다. 대상 및 방법 : 항갑상선제제 치료 종료후 TRH 자극 시험을 시행하였던 그레이브스 병 환자 총 84명 중, 정상적인 TSH 반응을 보이면서 1년 이상 추적 관찰이 가능하였던 32명의 환자를 대상으로 하였다. 처음 진단 시와 치료 종료 시에 T3(triiodothyronine), T4(thyroxine), T3/T4 비, TSH, TRAb, Anti-TPO Ab(anti-thyroperoxidase antibody)를 측정하였으며, 치료 종료 2개월후에는 TRH 자극 검사를 하여 TSH 증가폭(△TSH) 및 유리 T_(3) 증가폭(△FT_(3))을 구하였다. 모든 측정치는 평균±표준편차로 표시하였으며, SPSS software를 이용하여 Student's paired t-test, chi-square test, Wilcoxon signed ranks test를 시행하였고, 유의 수준 0.05 이하를 통계적으로 유의하다고 판단하였다. 결과 1) 총 32명의 환자 중 재발한 환자(Group Ⅰ)는 22명(69%) 이었으며, 재발한 환자(Group Ⅱ)는 10명(31%) 이었다. 2) 진단 초기 총T3 치는 Ⅰ 군에서 342.0±126.2ng/dl, Ⅱ 군에서 493.0 ±142.2 ng/dl로 Ⅱ군에 비해 유의하게 증가되었다(p<0.05). 3) Anti-TPO Ab는 Ⅰ군에서 2.9±4.4, Ⅱ군에서 22.3±22.3 U/mL로 나타나 Ⅱ군에서 유의하게 증가되었다.(p<0.05) 4) 양군에서 치료 종료후 재발시 대부분의 환자가 1년 이내에 재발하였다. 5) TRH 자극· 검사후 유리 T3 증가폭 및 TSH 증가폭은 양군간에 차이가 업ㅅ었다(1.5±0.9 vs 1.2±1.0 pmol/L, 12.54±7.56 vs 11.23±4.21 mU/L, p>0.05) 결론 : TRH 자극 검사후 정상적인 TSH 반응을 보인 환자에서 재발 및 관해여부를 치료 초기 T3 및 치료 종료시 Anti-TPO Ab로 예측할 수 있었으며, 이들 측정치가 증가해 있을수록 재발의 가능성이 많음을 알 수 있었다. 또한 투약 중단후 초기 12개원의 추적기간 동안 관해가 유지되면 그 이후엔 재발의 가능성이 현저히 줄어 들었으며, 이 후 좀더 많은 환자들을 대상으로 하는 장기적인 추적연구가 진행 되어야 할 것으로 사료된다. Background : Many studies were undertaken to find parameters that could predict the clinical course of patients with Graves' disease after withdrawal of antithyroid drugs. In many parameters, TRH (thyrotropin-releasing hormone) stimulation test and T3 suppression test were considered to be one of the most reliable for predicting remission. But recently, some studies showed that the measurement of free T3 and FT3 are to be a more accurate than other thyroid function test. In this study, we measured T_(3), T_(4), T_(3)/T_(4), TSH (thyroid stimulating hormone), TRAb (TSH receptor antibody), FT3 and other known useful parameters to compare the factors influencing the relapse of Graves disease after antithyroid medication. Patients and methods : Among the 84 Graves' disease patients who had done the TRH stimulation test after withdrawal of antithyroid medication, we examined 32 patients who showed normal TSH response and followed up more than one year. T_(3), T_(4), T_(3)/T_(4), TSH and TRAb levels were measured at the time of diagnosis and at the end of therapy. Serum TSH and FT_(3) levels were measured after TRH stimulation, after two months of withdrawal of medication. Statistical evaluation was Performed by SPSS software in combination with Student's Paired t-test, chi-square test, Wlicoxon signed-ranks test. p-value less than 0.05 was considered to be significant. Results 1. In the 32 patients with Graves disease, 10 patients(31%) relapsed(Group Ⅰ) and 22 Patients(69%) remained in remission(Group Ⅱ). 2. Initial serum T3 level was significantly higher in group Ⅰ than group Ⅱ(342.0 ±126.2 vs. 493.0±142.2 ng/dl, p<0.05). 3. Anti-TPO Ab level was significantly higher in group Ⅰ than group Ⅱ(22.3±22.3 vs 2.9±4.4 U/mL, p<0.05). 4. In group Ⅰ and Ⅱ most patients showed relapse within 1 year after antithyroid medication. 5. After TRH stimulation test, serum FT_(3), and TSH level were not significantly different between group I and Ⅱ(p>0.05). 6. Serum T_(4), T_(3)/T_(4), TSH, TRAb levels were not significantly different from group Ⅰ and Ⅱ. Conclusion : In this study, we found increased relapse rate in the patients with Graves' disease whose initial serum T3 and anti-TPO Ab levels were high, so these parameters could be used to predict the relapse of Graves' disease. In the case of more than 12 months remission period after withdrawal of antithyroid medication, no relapse wsa observed in this study, but study should be done in the large population of patients with Graves' disease.

특수가공용 공작기계의 쇼트피닝기 모델설계에 관한 연구

신용승,이승호,서유원,정성교 서울産業大學校 1999 논문집 Vol.49 No.2

As developing the technology in industry, the materials with superior grade of stiffiness and lightness are required, and hence the higher fatigue strength characteristics are necessary. Thus, the non-traditional machining to increase fatigue strength is becoming influential as very important technology. Considering environmental problem, the shot peening process is selected as a good process to increase fatigue strength. But the data related to shot peening process are not enough in this country. Shot peening process is essential to ensure repeatability and uniformity on a part to part and lot to lot basis, while conforming to the applicable specifications. The shot material, size, shape and hardness as well as velocity and impact angle must be controlled to provide consistency in peening results. In order to effectively control the shot peening process, parameters must be addressed in the following order, such as media control, coverage control, intensity control, equipment control and so on.

유화 Chlorosulfonated Polyethylene Rubber (CSM)의 제조 및 특성 연구

이은경,최교창,최세영 한국고무학회 2005 엘라스토머 및 콤포지트 Vol.40 No.1

본 연구에서는 CSM 에멀젼의 물성을 향상시키고자 금속성 가교제인 magnesium carbonate 및 calcium hydroxide를 첨가하여 가교밀도, 열적특성, 표면자유에너지 그리고 인장강도, 파단신율 및 인열강도 특성을 고찰하였다, 금속성 가교제인 magnesium carbonate 및 calcium hydroxide 양이 증가함에 따라 CSM 에멀젼 필름은 가교밀도는 증가하였고, 이에 내수성과 T_(g) 값도 증가하였다. 금속성 가교제로 magnesium carbonate를 첨가하였을 때 calcium hydroxide에 비해서 다소 높은 가교밀도와 T_(g) 값을 보였다. 하지만 CSM 에멀젼 필름의 표면에너지 및 기계적 특성들은 다소 다른거동을 보였다 Magnesium carbonate 0.75% 그리고 calcium hydroxide 1.0% 첨가한 경우가 가장 높은 표면 자유에너지 값과 인장강도 및 인열강도를 보였으나, 그 이상의 양을 첨가하였을 경우에는 오히려 감소함을 확인하였다. 그러므로 본 연구에서 CSM 에멀젼의 물성을 향상시키는데 적용되는 금속성 가교제로서 calcium hydroxide 보다 magnesium carbonate가 더 적당하며, 0.75% 첨가하였을 때 보다 향상된 물성을 얻을 수 있었다. In this work. magnesium carbonate and calcium hydroxide as metallic crosslinking agent were added to chlorosulfonated polyethylene rubber (CSM) emulsion to enhance the mechanical properties of emulsion film such as tensile strength. elongation at break, and tear strength and crosslinking density. thermal features, and surface energy were also investigated. Crosslinking density of the CSM emulsion film with increasing the amount of magnesium carbonate and calcium hydroxide increased. leading to the enhancement of water resistance. It was shown that compared with calcium hydroxide, magnesium carbonate had a little higher crosslinking density and To value. The surface energy and mechanical characteristics of the CSM emulsion film, however, showed somewhat different behaviors. The highest surface energy. tensile strength. and tear strength were observed when 0.75° o for magnesium carbonate and 1.0° o for calcium hydroxide were added respectively. Therefore. it can be concluded that as metallic crosslinking agent to improve water resistance and mechanical properties of the CSM emulsion, magnesium carbonate is more preferable to calcium hydroxide

발생원 유형에 따른 공기 중 휘발성 유기화합물의 비산배출 특성 평가

백성옥,김미현,서영교 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.4

In this study, the fugitive emission characteristic^ of airborne volatile organic compounds from different source categories were evaluated with respect to the concentrations measured in the vicinity of the sources. A total of 22 different sources were investigated, including gasoline storage and filling stations, painting spray booth, laundry, printing offices, textile industries, and a number of environment sanitary facilities such as landfill, wastewater treatment and incineration plants The target VOCs included 83 individual compounds, which were determined by adsorption sampling and thermal desorption coupled with GC/MS analysis. Overall, the aliphatic compounds appeared to be the most abundant class of compounds in terms of their concentrations, followed by aromatic, and halogenated hydrocarbons. As a single compound, however, toluene was the most abundant one, explaining 11% of the total VOC concentrations as an average of all the dataset. Among source categories. petroleum associated sources such as gasoline storage/filling stations, and laundry factory were identified as the most significant sources of aliphatic hydrocarbons, while aromatic VOCs were dominantly emitted from the sources handling organic solvents, such as painting booth, printing offices, and textile dyeing processes. However, there was no apparent pattern in terms of the contributions of each group to the total VOCs concentrations in environmental sanitary facilities. It was also found that the activated carbon adsorption tower installed for the VOC emission control in some facilities do not show any effective performances, which may result in the increased VOC levels in the ambient atmosphere.

Bezier Spline을 이용한 용접 로봇의 새로운 Weaving Motion 궤적 생성 알고리즘

정원지,김대영,서영교,홍형표,홍대선 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.3

In this paper, we propose a new weaving trajectory algorithm for the are welding of a articulated manipulator. The algorithm uses the theory of Bezier spline. We make a comparison between the conventional algorithms using Catmull-Rom curve and the new algorithms using Bezier spline. The proposed algorithm has been evaluated based on the MATLAB environment in order to illustrate its good performance. Through simulations, the proposed algorithm can result in high-speed and flexible weaving trajectory planning so that it s trajectory cannot penetrate into a base metal compared to the conventional algorithm using Catmull-Rom curve.

당(唐) 태종대(太宗代) 반위(反胃) 치료법의 개발과 백제(百濟) 의자왕(義慈王)의 질병

박준형 ( Park Jun-hyoung ),서영교 ( Seo Young-kyo ) 대구사학회 2021 대구사학 Vol.142 No.-

Tang China(618-907), which inherited the medical system of the preceding Sui China(589-618), attempted to reorganize it by absorbing various medical traditions which were then monopolized by hereditary medical families. The hereditary remedies and knowledge of medical specialists who were employed as government physicians were integrated into the state medical system, and the newly developed remedies were open to public. The development of Banwi (反胃, gastric disorder) remedy using donkey urine was one of the cases demonstrating the success of the early Tang medical system. The remedy, developed through a joint research by the physicians from three prestigious medical families in early Tang, was soon to be known to Baekje. King Uija (r. 641-660) of Bakje, who had been suffered from Banwi, dispatched envoys to Tang to ask to send Jiang Yuan-chang to Baekje in 644. The Baekje court seems to have regarded Jiang, a physician who participated in the development of new Banwi remedy, as the most qualified person to cure King Uija. Tang government, however, could not dispatch Jiang to Baekje as he was then working near Sichuan province, hundreds miles from Chang'an, the capital of Tang. As a result, King Uija missed a chance of being treated with the new remedy. Then Baekje, which had once promised not to attack Shilla by sending a prince to Tang, resumed invasion of Shilla in 645, spoiling Emperor Taizong's (r. 626-649) plan to mobilize Baekje's army in his campaign against Goguryeo. As the aftermath of this incident, the relation between Baekje and Tang was irreversibly deteriorated, while Shilla succeeded to consolidate the Shilla-Tang alliance which led to the fall of Baekje in 660. From the perspective of medical diplomacy between Baekje and Tang during the mid 7th centuries, Tang’s failure to meet Baekje’s request for the medical support might have had a grave effect on the Baekje’s decision to move against the Tang’s interests. Park, Jun-hyoung (Naval Academy / shimani5075@hanmail.net) Seo, Young-kyo (Jungwon University / syk367@naver.com)

전침 자극에 의한 오디 괄약근 운동성 변화에 관한 연구

이성구,김명완,김홍자,서동환,이상수,김동일,유교상,주연호,민병일,김지훈 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

Background/Aims: This study was designed to evaluated the effects of electroacupuncture on the sphincter of Oddi (SO) motility in humans and to correlate the manometric findings with plasma cholecystokinin (CCK) levels. Methods: Eleven patients (M: F= 5: 6) who had various kinds of biliary disorders were enrolled. SO motility was monitored with a conventional low-compliant continuously perfused technique using ERCP (n=9) or percutaneous transhepatic cholangioscope (n=2). After baseline monitoring for phasic wave contractions of SO, electroacupuncture was applied at a specific acupoint, GB 34, in these 11 patients. A nonspecific acupoint 5 cm away from GB 34 was selected as a control. Manometric parameters of SO were also checked in 6 subjects during stimulation of the control acupoint. CCK plasma levels were measured during the time course of electroacupuncture stimulation. Result: All the manometric parameters including the basal pressure of SO, amplitude, frequency and duration of phasic wave contraction of SO were significantly decreased (p< 0.05) during electroacupuncture stimulation. The inhibition of SO contractility was accompanied by increased CCK plasma levels. After removal of electroacupuncture stimulation, restoration of amplitude and duration to basal condition were noted. A tendency towards the return of SO contractility was also observed in basal pressure and frequency. Stimulation of the control acupoint, however, did not affect the SO contractility and plasma CCK levels. Conclusions: Electroacupuncture stimulation of acupoint GB 34 showed reversible inhibition of SO contraction in humans. We speculate that the response of SO to electroacupuncture stimulation may be mediated by some neurohormonal mechanisms including CCK release. (Korean Journal of Gastrointestinal Motility 2000;6:44-41)

Growth Characteristics of Enterobacter sakazakii Used to Develop a Predictive Model

Kyo-Young Seo,Sun-Kyung Heo,Dong-Ho Bae,Deog-Hwan Oh,Sang-Do Ha 한국식품과학회 2008 Food Science and Biotechnology Vol.17 No.3

A mathematical model was developed for predicting the growth rate of Enterobacter sakazakii in tryptic soy broth medium as a function of the combined effects of temperature (5, 10, 20, 30, and 40℃), pH (4, 5, 6, 7, 8, 9, and 10), and the NaCl concentration (0, 1, 2, 3, 4, 5, 6, 7, 8, 9, and 10%). With all experimental variables, the primary models showed a good fit (R²=0.8965 to 0.9994) to a modified Gompertz equation to obtain growth rates. The secondary model was ‘ln specific growth rate= ?0.38116+(0.01281*Temp)+(0.07993*pH)+(0.00618*NaCl)+(-0.00018*Temp²)+(-0.00551*pH²)+(-0.00093*NaCl²)+(0.00013*Temp*pH)+(-0.00038*Temp*NaCl)+(-0.00023*pH*NaCl)’. This model is thought to be appropriate for predicting growth rates on the basis of a correlation coefficient (r) 0.9579, a coefficient of determination (R²) 0.91, a mean square error 0.026, a bias factor 1.03, and an accuracy factor 1.13. Our secondary model provided reliable predictions of growth rates for E. sakazakii in broth with the combined effects of temperature, NaCl concentration, and pH.

Non-alcoholic fatty liver disease in young PCOS women

( Young Bin Won ),( Inha Lee ),( Jisun Yun ),( Jae Hoon Lee ),( Seok Kyo Seo ),( Sihyun Cho ),( Young Sik Choi ),( Byung Seok Lee ),( Bo-hyon Yun ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: To evaluate whether excessive hyperandrogenicity in relation to insulin resistance in adolescents with polycystic ovary syndrome (PCOS) contributes to the progression of metabolic disease and is associated with non-alcoholic fatty liver disease (NAFLD) compared to adults diagnosed with PCOS. Methods: This was a retrospective cohort study evaluating women with PCOS aged between 13 and 35 years at the point of PCOS diagnosis without any other health condition that could influence liver function. PCOS phenotype, BMI, waist circumference, fasting and 2 hours postprandial insulin and glucose, homeostasis model assessment of insulin resistance, fasting glucose insulin ratio, HDL, LDL, total cholesterol, triglycerides, DHEA-S, total testosterone, SHBG, free androgen index, Anti-mullerian hormone, Liver fibroscan, and abdominal ultrasound were assessed. Results: In PCOS women with NAFLD compared to those without, hypertension, metabolic syndrome, insulin resistance, SHBG, FAI, weight, BMI, waist circumference, total cholesterol, TG, HDL, LDL, HbA1c, fasting and 2 hours postprandial glucose, and AMH were statistically significantly higher. Interestingly, when adolescents and adults with PCOS were compared, there was no statistically significant difference in weight, BMI, waist circumference, HDL, insulin resistance, SHBG, FAI, obesity, metabolic syndrome, PCOS phenotype, and NAFLD occurrence. Conclusion: NAFLD frequently arises women with PCOS. Liver evaluation should be considered when patients present with elevated metabolic syndrome factors. Earlier diagnosis can lead to more timely treatment. Even though adolescents with PCOS have not been exposed to an insulin resistant environment for an extended period compared to adults, there were no statistically significant differences in the characteristics studied between adolescents and adults. Regardless of the age at which PCOS is diagnosed, comorbidities can lead to an increased metabolic risk so systematized investigation of NAFLD may be helpful.