녹차 및 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용

임성훈,서정순,윤영주,김광원,유소영,김화숙,국중기,이병래,차종희,박재윤 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.5

본 연구는 치아우식증에 관련된 Mutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연 생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 50% 에탄올을 이용하여 얻었다. 이들 추출물의 Mutans streptococci 표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장억제농도는 5 mg/ml이었다. 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다. Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatment. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casio tora were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5 mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea may be more effective than the tea prepared from C. tora in the prevention of enamel decalcification or dental caries around brackets.

유화중합을 이용한 4원공중합 바인더의 제조와 특성

임종민,하선희,임재길,설수덕 東亞大學校 大學院 2004 大學院論文集 Vol.29 No.-

Styrene-Acrylonitrile-Ethylacrylate-N-Methyloacryamide Prepared by emulsion polymerization has broad applications for additives such as paint binder, adhesive for wood and paper due to its low glass transition temperature which help to plasticize substrate resins. Since emulsion polymerization has disadvantage that surfactant and ionic initiator degrade properties of the product polymer, Poly(St-EA-AN-NMA) was synthesized using ammonium persulfate(APS) as catalyst and sodium lauryl sulfate(SLS) as emulsion to prevent the degradation. The copolymer binder product was internally plasticized and has enhanced colloid stability, adhesion, tensile strength and elongation. During binder emulsion polymerization, no coagulation and complete conversion occur with the reactant mixture of 3.34wt%/monomer ammonium persulfate, 2.33wt%/monomer sodium lauryl sulfate, and the balanced monomer that the weight ratio of Styrene, Ethylacrylate, Acrylonitrile are 47wt%/monomer, 32wt%/monomer, 6.4wt%/monomer. The activation energies for 37, 42, 47, 52% Styrene content were checked as 28.1~36kcal/mol by Kissinger's method. Actually, reasonable solid content could be considered as 56% because of activation energy and adhesive characteristics.

백서 간재생중 H2B Histone 유전자 발현에 대한 Octamer Binding Transcription Factor의 역할

임규,방재웅,최두식,손미영,이영철,박청,김태동,김영래,박종일,윤완희,박승길,황병두 한국노화학회 2001 한국노화학회지 Vol.11 No.1

실험실적 당뇨성 흰쥐에서 acetaminophen의 대사에 관한 연구

임은주,윤병재,윤병재,조희숙,김대재,최종원 경성대학교 환경문제연구소 2000 環境硏報 Vol.10 No.1

Acetaminophen is one of the most important drugs used for the treatment of mild to moderate pain when an anti-inflammatory effect is not necessary. Phenacetin, a prodrug that is metabolized to acetaminophen, is more toxic than its active metabolite and has no rational indications. In this study, we were observed activities of free radical generating enzymes, free radical scavenging enzymes and glutathione-related enzymes as well as detoxification mechanism of against acetaminophen-induced hepatotoxicity in STZ-induced hyperglycemic rat. Activities of cytochrome p450, cytochrome b5, aminopyrine demethylase and aniline hydroxylase were changed by the treatment acetaminophen in hyperglycemic rats. It was also observed that activities of conjugating enzymes as sulfotransferase and UDP-glucuronyltransferase was slightly changes against acetaminophen-induced in hyperglycemic rats. Acetaminophen results in the significantly decrease in the level of hepatic glutathione concentration and √-glutamylcysteon, synthetase activities in hyperglycemic rats. And, glutathine S-transferase, superoxide dismutase and glutathione peroxidase activities were significantly increased against acetaminophen-inducedas in hyperglycemic rats. Glutathione reductase and catalase were not affected for experimental state. Furthemore, acetaminophen highered serum alanine, aspartate aminotransferase, sorbitol dehydrogenase, √-glutamylpeptidase, alkaline phosphatase and lactate dehydrogenase activities in hyperglycemic rats. Key Words: Hepatotoxicity, D/M, Acetaminophen, Glutathione, Glutathlone S-transferase, √-glutamylcystein synthetase

우관상동맥 개구부 완전 폐쇄가 동반된 대동맥 판상부 협착증 1례

임상현,김종진,김희열,진승원,전희경,노태호,채장성,김재형,홍순조,최규보,윤정섭,김치경 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

韓國의 外貨換算會計에 관한 硏究

林在熙 圓光大學校 1995 論文集 Vol.29 No.1

The purpose of the reach is to transform accounting measures stated in foreign currincy units into more understandable and comperable Accounting measures to offer useful information, so that domestic users of accounting information may permit rational judgement and economic decision. The several methods for foreign currency translation may be grouped into four basic classes: current rate method. Korean accounting stadard prescribe the use of monetary-nonmonetary method, for foreign currency translation and allows a firm to be apply current rate method in translating foreign currency financial statements, but this standard has been criticized is being inappropirate to measure the impact of exchange on a firm's financial position. The recommendations are suggested in chapter four for foreign currency translation in Korea. Korean Accouting standard for foreign currency translation should be revised to proper situation after more than theoritical and empirical studies.

진폐증 환자의 결핵진단을 위한 중합효소연쇄반응법의 임상적응용

임철재,이경혜,박재희 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.1

Recent development in thepolymerase chain reaction(PCR) has brought an extraordinary opportunity for the rapid detection of M. tuberculosis in clinical specimens for the diagnosis of tuberculosis. Pneumoconiosis is a sort of pulmonary fibrosis consequent to inhalation of the respirable dust. The association between pulmonary tuberculosis and pneumoconiosis is well recognized. There is a 10-fold increase in the tuberculosis risk among the workers who have pneumoconiosis demonstrated by chest roentgenogram. The physicians managing the patients with pneumoconiosis have to maintain a high index of suspicion for the development of mycobacterial infection, since the diagnosis of tuberculosis is often difficult. Mycobacterium tuberculosis is a very slow growing organism and acid-fast bacillus(AFB) staining frequently shows false negative results, and therefore PCR would be a very rapid, easy and sensitive diagnostic method for the diagnosis of Mycobacterium tuberculosis in pneumoconiotic patients. To compare the PCR method with the conventional methods in diagnosing Mycobacterium tuberculosis in sputum, we used the sputa of 115 pneumoconiosis patients in Munkyeong Cheil Hospital. Of 32 pulmonary tuberculosis in the pneumoconiosis patients, 29 were PCR positive and were higher than 28, 20 positive by culture and AFB stain. Overall sensitivity, specificity, and which were 90.6, 91.5% respectively for the PCR assay ; 87.5, 100% for the culture method : 62.5, 98.7% for the AFB stain. The PCR assay is a rapid, efficient, sensitive method which can detect M. tuberculosis in pneumoconiosis patients, and further study should be followed for the development of the easier method.

유아교사의 생활양식과 건강상태에 관한 연구

정희남,임재택 부산대학교 보육종합센터 영유아보육연구소 2008 영유아보육연구 Vol.14 No.-

This study was to raise awareness of the importance which preschool teachers should practice right life style, by examining their lifestyle and health state. I looked into preschool teachers' food, clothing, and housing as a lifestyle, and their physical and psychological conditions as a health state. 400 preschool teachers in Busan were given a questionnaire, and 347 responses of them were used for this study. For achieving the purpose of this study, two research questions were as followings. 1. How is the life style of preschool teachers? 2. How is the status of preschool teachers? The result of this study showed that preschool teachers were more likely to wear mainly clothes processed by a softening agent in clothing life and many of them tended to eat fast or not to chew their food well when they had lunch or a snack in food life. In identified that in housing-related life, they were less likely to use a carpet or polyurethane mat and more likely to change teaching tools and furniture into new ones. Most of them were less likely to do regular exercise in medical life, and of the lifestyle, the clothing life averaged at the least, It also showed that their physical condition was not good, while their psychological condition was normal. Concerning the state of diseases, 50.1 percent were diagnosed with a disease by doctors. The most common disease they suffered from was anemia, followed by gastroenteric disorder, obesity, gynecologic diseases, ruptured disk and thyroid diseases.

연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

대졸 여성의 사회적 관계망과 구직 간의 관계

안재희,오재림 한국직업능력개발원 2007 직업능력개발연구 Vol.10 No.3

본 연구는 대졸여성들의 구직경로와 취업을 위해 동원한 사회적 관계망의 특성을 살펴보고 이것이 취업결과 간에 차이를 가져오는지 분석하였다. 우선, 구직경로를 보면 성별, 대학서열에 상관없이 대부분의 대졸자들이 구직정보 채널로 인터넷을 가장 많이 활용했지만 실제 구직경로는 성별, 여성집단 내 대학서열에 따라 차이를 보였다. 한편, 대졸 여성들의 사회적 관계망 특성을 보면, 대부분 대졸 이상의 학력을 지니고 자신의 경제적 지위와 비슷한 남성이 주류를 이루지만 연결강도는 여성 집단 내 대학서열에 따라 달라졌다. 그리고 비슷한 사회적 관계망을 구직과정에서 동원했어도 협력자로부터 받은 도움유형은 성별에 따라 달랐다. 이를 통해 대졸 여성의 구직과정은 젠더화 된 사회적 관계망이 개입되는 역동적 과정이라 하겠다. The purpose of this study is to analyze that the social network of female university graduates affect their job search process and job. This study intends to analyze that the female university graduates' job search activity is influenced by discriminate approach and utilization of social network along hakbol and sexism. For this study, the sample consisted of 293 persons who graduated from universities in Seoul from 2003 to 2004. The results of this study are as follows : First, there is a difference between the most used job search channel and the most successful job search channel by university hierarchy and gender. And the effect of institutional social network differs between genders, Secondly, the social network that female university graduates use to obtain job information is characterized by strong ties with university friends who are similar to respondents' economic position and educational level. Thirdly, these characters are interrelated with the information by their helpers and the job results.