비외상성 두개내 출혈 환자에서 심근손상의 발생과 예후에 미치는 영향

강구현,황성호,이강현,조준휘,김성환,문중범,박해상,이서영,이성수,김헌주 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Objective: The aim of this study was to investigate the clinical significance of myocardial injuries in patients with nontraumatic intracranial hemorrhage by identifying the occurrence of myocardial injury and defining its correlation with subsequent cardiovascular events. Subjects and methods: One hundred twenty-four patients with nontraumatic intracraninal hemorrhage presented to the emergency department within six hours from onset of symptoms were enrolled. Brain CT, serial electrocardiography, and echocardiography were done at the emergency center. Blood samples for troponin I and creatine kinase(CK)-MB were drawn immediately and eight hours after admission, Troponin I and CK-MB were measured using a chemiluminescent immunoassay, respectively. Results: Electrocardiographic and echocardiography abnormalities were found in 65 cases(52.4%) and 21 cases(17%), respectively. Serum troponin I and creative kinase-MB were increased in 35 cases (28.2%) and in 58 cases(46.8%), respectively. Abnormal findings of echocardiography and ECG, as well as elevated levels of serum troponin I and creative kinase-MB, were associated with an increased risk of cardiovascular event and survival. Logistic regression analysis revealed that an abnormal echcocardiographic finding and elevation of serum troponin I were factors associated with the occurrence an adverse cardiovascular event and that electrocardiographic abnormalities and initial mental status were factors associated with poor prognosis. Conclusion: This study reveals that actual myocardial injury develops in a significant proportion of patients with nontraumatic intracranial hemorrhage and that the development of the myocardial injury is associated with an adverse cardiovascular event that occurs during admission.

전조가 없는 편두통과 동반되어 나타난 일과성 전기억상실증

강성진,김광수,이지현,김종국,김민정 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Transient global amnesia(TGA) is a transient neurological syndrome presenting total memory impairment. Although the pathophysiology of TGA is not yet clear, it may be associated with migraine or ischemia. A sixty seven year-old woman complained total memory impairment that occurred during migraine attack. The cognitive function test revealed impairment of orientation and memory. Her brain MRI, EEG and SPECT didn’t show any abnormal findings. Therefore TGA may be caused by migraine induced cerebral ischemia.

[논문]용접부의 피로 파손모드 평가에 대한 구조응력기법의 적용에 관한 연구

강성원,김명현,김정환 釜山大學校生産技術硏究所 2006 生産技術硏究所論文集 Vol.65 No.-

반복 하중을 받게 되는 하중전달형의 필릿 용접이음에서는 용접 토우부 뿐만 아니라 용입 부족부 선단에서도 응력집중을 일으키고 피로균열이 발생/ 전파하는 경우가 있다. 특히/ 용접 루트부에서 발생한 균열은 육안관찰이 불가능하고 초음파 탐상등에 의한 비파괴 검사에 의해서도 검출이 곤란한 경우가 많다. 이것은 중대한 손상을 일으키기 까지 방치되는 경우가 많기 때문에 용접 루트부에서 발생하는 균열에 대한 연구는 현재 활발히 진행되고 있다. 본 연구에서는 최근 유한요소 해석시 요소의 크기에 둔감하다고 알려진 구조응력 기법을 이용하여 용입 부족부를 가지는 하중전달형 필릿 용접부의 피로 파손모드를 평가하였다. 용접부 다리길이의 변화에 따른 사례 연구를 통하여 용접 루트부의 파손을 피할 수 있는 용접부 시공기준에 관한 연구를 수행하였으며 이에 대한 구조응력 기법의 적용 가능성을 검토하였다.

방사선치료 후 영구치 치배 발육장애 증례보고 : REPORT OF CASE

강명봉,김영재,김정욱,장기택,이상훈,한세현,김종철 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

두경부 악성 종양에 대한 방사선치료는 유용한 방법이다. 하지만 방사선치료의 부작용으로 다양한 구강내 합병증을 동반한다. 이 글에서 치열 발육 단계에 방사선치료를 받은 두 증례를 보고하는 바이다. 첫 번째 증례는 생후 19개월에 급성 골수성 백혈병으로 진단 받아 방사선치료를 받은 7세 여자 환아로 영구치 치배의 선천적 결손과 왜소치 소견을 보였다. 두 번째 증례에서는 생후 13개월에 양측성 망막아세포종으로 진단 받아 방사선치료를 받았고 영구치 치배의 선천적 결손, 왜소치, 치근의 저형성 그리고 법랑질 저형성증 소견을 보였다. Radiotherapy for head and neck tumors is a viable treatment modality. However, a wide range of potentially debilitating dental complications may be accompanied by this treatment. We report two cases of developmental disturbance of permanent tooth germs after radiotherapy. The one was that of a seven-year-old girl, who had congenitally missing teeth, and microdontia of permanent tooth germs. she had received radiotherapy for acute myelocytic leukemia at the age of 19 months. The other was that of a nine-year-old boy, in which congenitally missing teeth, microdontia, root hypoplasia, and enamel hypoplasia of permanent teeth were observed. He had undergone a course of radiotherapy for bilateral retinoblastoma at the age of 13 months.

위선암에서 p53과 EGFR 및 PCNA 발현에 관한 연구

강현욱,양승하,강상균 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1

Expression of oncogene in the gastric adenocarcinoma was considered as a determinant factor of cancer progression or prognosis by some authors, however, the results were so fluctuated according to the authors that there was no uniform agreement in their clinicopathological correlation as well as in its practical application. To evaluate correlation between the pathologic finding and the expression of p53, EGFR and PCNA, immunohistochemical studies were performed on paraffin-embedded sections of 84 gastric adenocarcinomas. Pathologic findings were classified as 4 subgroups by their histologic types, differentiation, invasion and lymph node metastasis. The correlation of PCNA labelling index with various clinicopathologic factors and oncogene expression was studied. The results were as follows; 1. p53 expression was seen in 47cases(55.56%) of gastric carcinoma, and correlation between p53 expression with tumor type, differentiation, invasion and lymph node metastasis was not proved. EGFR positive expression was found in 37(44.05%) cases and was increased in advanced gastric carcinoma, and cases of lymph node metastasis. 2. Co-expression of p53 and EGFR was observed in 18 cases(33.33%), suggesting existence of both oncogene in the same case, while both negative cases were 18 cases(33.33%) that suggest the possibility of presence of the other factors. 3. PCNA labelling index was higher in advanced gastric carcinoma and in cases of lymph node metastasis, but there was no statistical significance. 4. There was no statistical significance between PCNALI and p53 expression. 5. PCNALI and EGFR expression was parallel with pathologic finding such as differentiation, progression and metastasis of the carcinoma, these results suggest that there was significant correlation between PCNALI and EGFR. 6. PCNALI was statistically significant between two groups of both p53 and EGFR positive and both negative. 7. PCNALI showed statistical significance between EGFR positive and negative groups in cases of lymph node metastasis. In summary, the value of p53 expression as a prognostic factor was still doubtful but EGFR and PCNA expression tended to be associated with tumor progression and seemed to be objective and reliable prognostic factors, respectively. Combined method of EGFR and PCNA thought to be more helpful in preoperative decision or prediction of prognosis in gastric carcinoma.

최초 침전지를 대체하기 위한 고속생물막 침전지의 특성에 관한 연구

강용태,장성부,조용현 동아대학교 건설기술연구소 2003 硏究報告 Vol.27 No.1

It is not easy to find reasonable area for construction of wastewater treatment facility. and biological treatment such as a conventional activated sludge process can't remove non-point source pollutant in initial rainfall, sufficiently. So if we use physical treatment and disinfection process, combined sewer overflows don't cause significant pollution. In this study, to reduce area of wastewater treatment facility, the rapid biofilm clarifier was configurated and its characteristics were analyzed according to the velocity of filtration and cycles of backwash. Specific characteristics of the rapid biofilm clarifier with 50 ㎥/d of volume were represented that Turbidity and SS removal rate was 30.2%, 30.9% respectively, and that of BOD and COD was 22.0%, 21.0% without regard to change of quality of raw water. By comparing the rapid biofilm clarifier and clarifier of conventional activated sludge process with having 50 ㎥/㎡·d, of surface-loading rate and 2.0 m of depth, we could know the rapid biofilm clarifier could reduce area of clarifier 11 times as much than that of conventional activated sludge process. Cycle of backwash was represented as 24, 18, and 24 hours when velocity of filtration was 222 ㎥/㎡·d, 333 ㎥/㎡·d, and 555 ㎥/㎡·d, and BOD. SS biologically removed in the rapid biofilm clarifier was 342.80, 346.82 g/d, 258.08, 222.72 g/d, and 143.36, 136.52 g/d respectively.

오존을 이용한 하수2차 처리수의 처리 및 슬러지 감량화에 관한 연구

강용태,조용현,장성부,최선영 東亞大學校建設技術硏究所 2004 硏究論文集 Vol.28 No.1

Nowadays, most of water source is deteriorating due to depending on surface water more than 90%. New disinfection facilities are urgent because a provision of total coliforms was made newly and have gone into effect since in January 2003 for securing of water source. And waste sludge treatments is an outstanding environment question because of several reasons such as increases of waste sludge, high cost of waste sludge treatment and prohibition of sludge treatment method having been utilized. In this study, specific characteristics of ozone treatment for wastewater effluent and volume reduction of waste sludge were studied with pilot-plant. The results of the study are followed: A removal efficiencies of total-coliforms with ozone dose change of 1.6, 2.6, 3.5, 4.5gO3/m3Water were 73.7, 88.1, 95.6, 97.2% .respectively. And MLSS reduction rate of waste sludge with ozone dose change of 0.2, 0.4, 0.6, 0.8gO3/gSS were 38.0, 50.0, 57.9, 62.0%.respectively. CODMn removal efficiency of that was 50.5, 65.0, 76.6, 82.1% respectively and SV30 reduced 92.6% even if ozone dose was 0.2gO3/gSS. Therefore, it is found that ozone treatment is very effective for sludge volume reduction and solidㆍliquid separation.

한국인의 각막에 관한 연구

강현식,김대년,김상연,강인산,박은규,서용원 대구보건대학 1999 대구보건대학 論文集 Vol.19 No.-

As the results of measurement of the radius of corneal curvature by keratometry for the right eye of 100 subjects, the steep meridian radius is 7.21㎜ to 8.27㎜ and flat meridian is 7.45㎜ to 8.65㎜, for the left eye the steep meridian radius is 7.30㎜ to 8.35㎜, and flat meridian is 7.45㎜ to 8.72㎜. The mean value of radius of corneal curvature is 7.8㎜ for night eye, 7.8㎜ for left eye. The results of measurement of P-value by topography, it is ranged from 0.45 to 0.91 for the night eye, 0.55 to 0.90 for the left eye, mean value is 0.756 for right eye, 0.735 for left eye respectively. That means the corneal shape is ellipses. The corneal thickness is measured 0.69㎜ 10°degree to the nasal, 0.76㎜ 20°degree to the nasal, 0.66㎜ 10°degree to the temporal, 0.72㎜ 20° degree to the temporal from the visual axis and 0.60㎜ at the central position. The horizontal size of corneal is 11.34㎜ for the night eye, 11.373㎜ for left eye. Those data can be used for contact lens design and fitting.

2007년 대한감염학회 권장 성인 예방접종 권장안

강진한,김홍빈,손장욱,이상오,정문현,정희진,최영화,최정현,최준용,최희정 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

In 2007, the Korean Society of Infectious Diseases recommended an immunization schedule for adults residing in Korea. This recommendation includes four categories: standard immunization for healthy persons, supplementary immunization for persons with underlying illnesses, recommendations for health-care personnel and for international travelers. The Standard Immunization Schedule consists of universal vaccination (tetanus-diphtheria/tetanus-diphtheria-pertussis (Td/Tdap); hepatitis A vaccine for persons aged 20s; human papilloma virus vaccine for women under 26 years old; meningococcal vaccine for military recruits and college students in dormitories; influenza vaccination for persons aged 50 years or more and pregnant women; and pneumococcal vaccination for persons aged 65 years or more) and catch-up vaccination (hepatitis A vaccine for persons aged 30s; hepatitis B vaccine, varicella and MMR vaccines for persons who have uncertain specific immunities). The Supplementary Immunization Schedule recommends 4 vaccines, i.e., pneumococcal, influenza, meningococcal, and Haemophilus influenzae type b, appropriate to the underlying illnesses, and confirmation of the presence of antibodies to hepatitis A and hepatitis B. The Recommendation for Health-Care Personnel includes universal vaccination (influenza and pertussis) and catch-up vaccination (hepatitis B, measles-mumps-rubella and varicella for seronegative health-care personnel). The Recommended Immunization for International Travelers focuses reinforcement of vaccinations for healthy persons and includes certain immunizations necessary for international travel (yellow fever, meningococcal, plaque, tick-borne encephalitis, and cholera). These guidelines can be seen at www.ksid.or.kr.

CORBA 기반의 분산 객체 관리 모델 구현

강재효,서재현,김상균 인제대학교 1998 仁濟論叢 Vol.14 No.1

본 논문에서는 CORBA(Common Object Request Broker Architecture) 객체의 관리를 위한 ObjectMonitor의 설계를 제안한다. 본 ObjectMonitor의 특징을 요약해 보면 다음과 같다. 첫째는 URN(Uniform Resource Name)기반의 객체에 대한 위치 투명성은 물론 한 단계 추가된 추상화기법을 통해 위치 독립성을 제공한다. 둘째는 서버들간의 부하 분담(Load Balancing)을 위한 정책을 쉽게 그리고 동적으로 제공한다. 셋째는 오브젝트의 오류 상황을 체크하여 제어할 수 있는 기능을 첨가함으로써 결함 허용(Fault Tolerant) 시스템을 지원한다. 이런 특징들을 바탕으로, 제안된 ObjectMonitor는 이질의 분산환경에서의 신뢰성을 부여하고, 확장이 용이하며, 또한 객체의 이동성을 제공한다. 이런 특성은 클라이언트와 서버간의 고품질의 서비스 제공을 가능하게 한다. This paper proposes a design of ObjectMonitor to manage CORBA(Common Object Request Broker Architecture) Object. The features of this ObjectMonitor are: 1) this provides not only Location Transparency of object based on URN (Uniform Resource Name) but also Location Independence through the abstract technics developed one more level; 2) it provides the policy for Load Balancing among servers easier and dynamically; 3) it supports Fault Tolerant System by adding functions that detect the error situations and fix them. The ObjectMonitor gives reliability in different distributed environment, and makes it easy to extend, and provides migration of objects. These kinds of features make it possible to give high quality service between Client and Server. Moreover, performing real-time object management dynamically, we get synergy that real time Load Balancing Policy can be used easily.