ART2 신경회로망을 이용한 공구마모 모니터링

오동백,노민석,장우일,최국진,홍대선 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

Titanium alloys have been mainly used for aircraft components as well as implant materials. Although a number of cutting tools and cutting methods have been developed for improving the cutting processes, they have difficulties such as tool wear and failure. This study considers a novel approach to on-line monitoring of tool wear and failure in titanium alloy cutting processes. The on-line monitoring system mainly consists of two parts: The one is on-line data acquisition with sensors and a DSP board through LabView and a web server, and the other is learning and prediction of tool wear and failure using an ART2 neural network algorithm. The system is installed at an on-site machine tool to monitor high speed steel(HSS) tools for cutting titanium alloy. A number of experiment are carried out to demonstrate the effectiveness of the proposed system.

두경부자세 및 혀, 설골의 위치가 두개안면형태에 미치는 영향에 관한 연구

오진섭,태기출,국윤아,김상철 대한치과교정학회 1998 대한치과교정학회지 Vol.28 No.4

두경부 자세 및 혀, 설골의 위치와 두개안면골격간의 연관성을 알아보기 위해, 원광대학교 치과대학 재학생 중 선천적 두경부 이상이나 결손치가 없고 과거 교정 치료나 보철치료의 경험이 없는 남자 50명과 여자 40명을 대상으로 natural head position(NHP)상태에서 두부방사선 사진을 채득하여 전통적인 두개내 참고선과 두개의 진성 참고선을 이용하여 계속한 결과 다음과 같은 결론을 얻었다. 1. 두경부 자세변수들에서는 남녀간 차이가 없었으나, 설골의 위치는 남자가 여자에 비해 더 전하방에 위치하였으며, 더 큰 전하방 경사도를 보였다. 2. 경추의 경사도가 클수록 NHP에서 안면돌출도는 작게 나타났으며, 경추의 전방만곡이 증가할수록 수직적인 안모형태를 보였다. 3. 두경부각이 작을수록 두개저에 대하여 설골이 전방에 위치하였으며, 두경부각과 설골의 수직적인 위치는 연관성을 보이지 않았다. 4. 하악골이 전돌될수록 설골은 전방에 위치하였으며, 두개안면형태와 설골의 수직적인 위치는 미약한 연관성을 나타냈다. The purpose of this study was to examine the associations of head posture, the position of the tongue or the hyoid bone to craniofacial structure. Cephalograms taken in Natural head position(NHP) of 90 dental students (50 in male, 40 in female, 20 to 30 years in age) were traced and measured using the extracranial true horizontal and vertical lines. The obtained results were as follows; 1. There was no sex difference in head posture, but the hyoid bone was placed anteroinferiorly in male more than in female and anteroinferior inclination of the hyoid bone showed greatly in male. 2. The more inclined was the cervical column, the less prognathic was the face in natural head posture, and the larger cervical curvature, the more vertical pattern of the face. 3. The less small showed craniocervical angulation, the more anteriorly placed was the hyoid bone to the cranial base, and there was no significantly association between craniocervical angulation and the vertical position of the hyoid bone. 4. The more prognathic was the mandible, the more anteriorly placed was the hyoid bone, and there was slightly association between the craniofacial morphology and the vertical position of the hyoid bone.

實證的 實驗을 통해 본 옛 印刷文化

오국진 西原大學校湖西文化硏究所 1999 湖西文化論叢 Vol.13 No.-

이상과 같이 옛 인쇄술의 변천과정을 간략하게 더듬어 보았다. 요약컨대, 인류 문명이 발전되면서 인쇄술이 어떠한 방법으로 변천하였고 앞으로 어떻게 연구되어야 할지를 실증적 실험을 통해 알아 보았으며 첨단 정보화 시대를 맞아 한 세기를 마감하는 활자 문화의 종주국으로서의 위상과 천년 수명으로 가진 우리 한지의 특성, 우수성을 알고 가꾸어 고인쇄물과 더불어 관광 상품화할 수 있는 방안을 모색해야 할 것이다. 그 방안으로 ๐ 국내 유일의 고인쇄박물관다운 특성이 있고 개성을 살닌 전시 방향 재고 1. 고서 위주 전시 지양(도서관, 고서점이 아니며 책의 내용을 연구하는 곳도 아 님) 2. 책이 나오기까지의 기능(과정) 전개로 산교육장화 ๐ 고인쇄술 활용 방안 예) 1. 훈민정음의 해례본 한글판 인출 보급 : 교육효과 2. 한지의 우수성을 살린 각종 보존기록문서 발간 연구 3. 훈・포장, 임명장 생산 보급 연구

우리나라 現行 敎育自治制에 關한 硏究

吳國鎭 건국대학교 교육대학원 1988 敎育論叢 Vol.10 No.-

Purpose of the Study The main purposes of this study were twofold: (1) to find out problems in current educational systems of the provincial and local board education through review of the literature previous studies, and together 'with questromnaire survey' and(2) to contirbute to a newly adopting educational system of local autonomy in Korea. Method of the Study Methods of the Study also were twofold: firstly, review of the literature, previous studies, and foreign local educational systems to find out problems of current systems of Korean provincial and local boards of education and secondly, a survey to disiouer alternative systems of both boards of education by questionnaire developed by this researcher and other consultants. Questionnaire were consisted of 25 items from five areas, (1)the nature, structures and organization of the both board of education , (2)power relations between the Ministry of Education, provincial and local boards of education, (3)relations between general administrative structure and educational structure, (4) professionalization of educational administration, and (5) educational finance from the above review of literature. The questionnaire was administered to 595 subjects consisted of teachers, educational professionals, educational Administrative staffs, university professors, and parents of students. These subjects were subgrouped by status, age and sex to compare the opinions and ideas. Findings of the Study Major findings of the study from 5 areas were summarized as follows: A.The nature, structure and organization of Board of Education. (1)Boards of Education should be decision-making body and superintendents should function as the chief executive at the both levels of provincial, and local board of education. (2)Fifteen to thirty board members of education at provincial level should be elected by local country representatives, and they should represent distizens, vocational organizations, and ex-officios, desirable term of the board member was 4 years and more term might be extended. (3)Members of board of education should be honorable and non-partisan position, representative members of county citizens among them and they should have resided more than 3years in that district, and vocational representatives members should be elected from elementary and secondary teachers. (4)Superintendents of provincial board of education requires 20 or more years of teaching experience, master's or higher degree and non-partisan. He should be elected by provincial board of education for the term of 4 years allowing one more term. (5)Superintendents of local school districts requires 15 or more year's teaching experience. He should be elected by local board of education for the term of 4 years allowing one more term and be a non-partisan. B.Power relation between the Ministry of Education and Provincial and Local Boards of Education. (6)The Ministry of Education should focus on policy-making and planning at the national level, developing and supporting provincial and local level education, and the other matters should be decentralized. C. Relations between general administrative structure and local educational structures. (7)Superintendents could be concurrently the representative members of the same province as an ex-officios to assure the co-operation of representatives from the province. (8)Existing veto system by the Governor should be abolished. Chair of the board of education should be elected by the majority rule among same board members, and board of education could have actual power to decide and execute educational matters independently. D. Professionalization of Educational Administration. (9)Superintendents at local school districts should be elected from educational professionals. (10)Provincial and local governments should have responsibilities for the educational finance, and central government should maintain balanced development of provincial and local education. E. Educational Finance of Board of Education. (11)The amount of educational expenditures from provincial and local governments should be increased for the stability of educational finance. (12)Current source of educational tax should be changed from national tax to local one, and be increased and stabilized by allocating appropriate proportion of local taxes.

골내 고정 장치용 초내식성 오스테나이트 및 듀플렉스 스테인리스강 가공재의 특성

오근택,강국진,박용수,김경남 大韓齒科器材學會 2003 대한치과재료학회지 Vol.30 No.3

Nickel is one of the most common causes of allergic contact dermatitis and hypersensitivity. In case of stainless steel as biomaterials, the higher the corrosion resistance and the lower the nickel content, the better it is or the human body. However, because nickel plays an essential role in the stabilization of the austenitic phase and the corrosion resistance of stainless steel, it is difficult to remove the nickel from the constituents of stainless steels completely. Therefore, the purpose of this study was to investigate corrosion resistance, cytotoxicity, and mechanical property of super stainless steels, which had high corrosion resistance by synergistic effect of Mo(or W) and N, with respect to nickel content and to evaluate their potential for orthodontic applications. Super austenitic stainless steel(SR-50A) had high nickel content of 22% and super duplex stainless steels nickel contents of 6~10%. Super austenitic and duplex stainless steels had nitrogen contents of above 0.2%. Also, these steels had high Mo or W contents which were able to increase the localized corrosion resistance. In terms of hardness, super stainless steels, which had Vickers hardness values of 374~400 Hv in cold-rolled state and 186~285 Hv in annealed state, exhibited higher values than 316L S. S.. Duplex stainless steels exhibited higher mechanical properties than austenitic stainless steels. In terms of corrosion resistance, super stainless steels exhibited lower passive current density(2.3~3.8 ㎂/cm^2) than pure Ti(6.6㎂/cm^2) in the body-simulated solution and similar potentiodynamic polarization behaviors. Pitting corrosion occurred in 316L S. S. but not in the others. Thus these steels were considered to have high corrosion resistance in the human body. In terms of cytotoxicity, SR-5OA and SAF2507 exhibited none cytotoxicity and the others slight. This results indicated that the cytotoxicity of alloys containing nickel had no relation with nickel content because SR-5OA with the highest nickel content exhibited none cytetoxicity In conclusion, it is considered that super stainless steels with high corrosion resistance and good biocompatibility can be used for orthodontic applications because of the enhanced passive film by high addition of Mo, W, N, etc.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

한국에서의 간질의 사회적 낙인

이상암,유희정,허경,박형국,신동진,송홍기,정원영,권오영,이성수,김요식,김성은,이병인 대한간질학회 2002 대한간질학회지 Vol.6 No.2

Opuntia humifusa Ameliorated Cerulein-Induced Acute Pancreatitis

Choi, Sun Bok,Bae, Gi-Sang,Park, Kyoung-Chel,Jo, Il-Joo,Seo, Seung-Hee,Song, Kyung,Lee, Dong-Sung,Oh, Hyuncheol,Kim, Youn-Chul,Kim, Jong-Jin,Shin, Yong Kook,Park, Jin-Han,Seo, Min-Jun,Song, Ho-Joon,Pa by Lippincott Williams Wilkins. 2014 PANCREAS Vol.43 No.1

OBJECTIVE: The aim of this study was to evaluate the effects of Opuntia humifusa (OH) on cerulein-induced acute pancreatitis (AP). METHODS: Acute pancreatitis was induced via intraperitoneal injection of cholecystokinin analog cerulein (50 μg/kg). In the OH pretreatment group, OH was administered intraperitoneally (100, 250, or 500 mg/kg) 1 hour before first cerulein injection. In the posttreatment group, OH was administered intraperitoneally (500 mg/kg) 1 hour after the first cerulein injection. Furthermore, we isolated the pancreatic acinar cells using collagenase method, then investigated the acinar cell viability, cytokine productions, and the regulating mechanisms. RESULTS: The both pretreatment and posttreatment of OH treatment attenuated the severity of AP, as shown by the histology of the pancreas and lung, and inhibited neutrophil infiltration; serum amylase and lipase activities; proinflammatory cytokine expression such as interleukin 1, interleukin 6, and tumor necrosis factor α; and cell death including apoptosis and necrosis. Furthermore, OH inhibited the activation of c-Jun N-terminal kinases. CONCLUSIONS: These results suggest that OH reduces the severity of AP by inhibiting acinar cell death through c-Jun N-terminal kinases.

Expression of Aquaporin-1, Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor-1 in the Peritoneal Tissues of Peritoneal Dialysis Patients

( Kook Hwan Oh ),( Sung Kyun Kim ),( Eun Sook Nam ),( Ji Eun Oh ),( Soo Jin Kim ),( Se Won Oh ),( Ho Jun Chin ),( Ki Young Na ),( Dong Wan Chae ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.3

Purpose: AQP-1 (Aquaporin-1) and VEGF (vascular endothelial growth factor) are known to play an important role in ultrafiltration in peritoneal dialysis. The aim of this study was to evaluate the expression of AQP-1 and VEGF and VEGFR-1 (VEGF type 1 receptor) in peritoneums obtained from uremic non-dialyzed patients and peritoneal dialysis patients and to see if expression of these molecules are correlated with each other and with pathological findings in peritoneum. Methods: Peritoneal expressions of AQP-1, VEGF and VEGFR-1 were examined by immunohistochemistry using specific antibody to each molecule. The degree of vascular proliferation and inflammation in peritoneal tissues were assessed semi-quantitatively by a single pathologist. Results: AQP-1, VEGF and VEGFR-1 were mainly expressed in the vascular endothelial cells in the peritoneum. No significant difference in peritoneal expression of these molecules was found according to the clinical situations in which peritoneal tissues were obtained. The degree of expression of AQP-1 and VEGF were related to each other but not related to expression of VEGFR-1. The expressions of AQP-1 and VEGF were related to the vascular proliferation. The expression of AQP-1 was also related to inflammation. Conclusion: In end-stage renal disease patients before and after initiation of peritoneal dialysis, the peritoneal expressions of AQP-1 and VEGF were related to vascular proliferation. Inflammation might have some influence in expression of AQP-1.

Case Reports : Ectopic ACTH Syndrome and Severe Hypokalemia Associated with Suspicious Pancreatic Malignancy: A Case Report

( Jin Ho Hwang ),( Seung Seok Han ),( Eun Jin Cho ),( Dong Ki Kim ),( Kook Hwan Oh ),( Kwon Wook Joo ),( Yon Su Kim ),( Jin Suk Han ),( Suhng Gwon Kim ),( Cu Rie Ahn ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.5

A 72-year-old woman had a 1-month history of general weakness. Previously, after rectal cancer was treated with a low anterior resection, 12 cycles of adjuvant chemotherapy with 5-fluorouracil plus leucovorin was undergone. Follow-up examination showed no evidence of recurrence. However, she suffered from general weakness attributable to hypokalemia, which was refractory to potassium replacement therapy. After further work-up of the hypokalemia, Cushing`s syndrome and ectopic adrenocorticotropic hormone (ACTH) syndrome were diagnosed from the laboratory findings that included a markedly elevated level of 24-hour urine-free cortisol. Several imaging studies revealed masses of the pancreas and other organs, which was more likely to be pancreatic cancer. This case is interesting in that cancerous lesions were identified during work-up of hypokalemia.