폐경기 여성에서 1년간 호르몬 대치 요법이 혈청 지질에 미치는 영향

이해혁,남계현,김승형,이임순,이권해,최승도 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Cardiovascular disease is one of the most common cause of death in postmenopausal women. After the onset of menopause, the risk of cardiovascular disease is increased. Several risk factors of cardiovascular disease are well known to us. Among the risk factors, the changes of lipid profiles are roles for cardiovascular disease. Estrogen appears to protect the development of cardiovascular disease, by several mechanism. Especially the protective effect is believed to be mediated by the changes of lipid profiles. Decreased high-density lipoprotein (HDL)-cholesterol and increased low density lipoprotein (LDL)-cholesterol are important factors for development of cardiovascular disease. The purpose of this study was to evaluate the effect of hormone replacement therapy on the lipid profiles to include total cholesterol (TC), high density lipoprotein(HDL)-cholesterol, low density lipoprotein(LDL)-cholesterol, and triglycerides. We measured lipid profiles in 31 postmenopausal women and gave each conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 5mg, day 1-12) for 12months. The levels of serum TC, LDL-cholesterol, and triglycerides were decreased significantly (p<0.05) and HDL-cholesterol was increased significantly (p<0.05) after 12months of hormone replacement therapy. These data suggest that hormone replacement therapy appears to protect agianst the development of cardiovascular disease by the changes of lipid profiles.

갱년기 여성의 호르몬 대치 요법에 대한 수용율

이임순,장진영,이정재,이순곤,이권해,이해혁,김승형 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Purpose: We have evaluated the compliance of hormone replacement therapy. Method: There are 185 climacteric women who are divided into three groups (Group I, Group II, Group III). Group I is given conjugated equine estrogen(CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate(MPA, 5mg, day 1-12). Group II is given conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 2.5mg, day 1-30), Group III is given only conjugated equine estrogen(CEE, 0.625mg, day 1-30). Results: 1) The compliance rate of hormone replacement therapy during three months is 77.9% including each Group I : 77.7%, Group Ⅱ : 76.1%, Group Ⅲ :80.4%. 2) The compliance rate of hormone replacement therapy during six months is 60.7% including each Group Ⅰ:52.9%, Group Ⅱ: 56.4%, Group Ⅲ: 79.5%. 3) The compliance rate of hormone replacement therapy during nine months is 49.7% including each Group Ⅰ: 45.5%, Group Ⅱ:41.7%, Group Ⅲ: 64.3%. 4) The compliance rate of hormone replacement therapy during a year is 44.4% including each Group Ⅰ: 40.2%, Group Ⅱ:35.3%, Group Ⅲ: 59.5%. Conclusion : It is vital that we maximize compliance if patients are to receive the full benefits from hormone replacement therapy. We think that physicians who prescribe hormone replacement therapy for climacteric women should enough explain the purpose, risks, and side effect of treatment for maximizing compliance of hormone replacement therapy.

모래상자놀이를 통한 부적응 행동유아의 자아존중감 및 친사회적 행동 변화양상에 관한 연구

이연승(Lee Yeon Seung),유명순(Yoo Myeong Soon) 한국어린이미디어학회 2007 어린이미디어연구 Vol.6 No.2

본 연구는 모래상자놀이를 통한 부적응 행동유아의 자아존중감과 친사회적 행동의 변화양상에 관한 연구로서, 모래상자놀이가 유아들의 전인적인 성장발달을 위한 기초자료로 활용될 수 있는지 확인하는데 그 목적이 있다. 이러한 연구목적을 달성하기 위하여, 부적응한 행동유아가 모래상자놀이를 통하여 어떻게 자신을 표현하고 집중할 수 있는 기회가 늘어나고, 또한 자아존중감 향상에 도움을 받으며, 친사회적 행동 관계에 어떤 영향을 주는지에 대한 비교 분석을 하였다. 연구과정은 25주에 걸쳐 사전검사, 모래상자놀이실시, 사후검사 순으로 진행되었다. 본 연구의 결과는 다음과 같다; 모래상자놀이를 통한 부적응 행동유아의 자아존중감 변화양상은 하위요인인 지적 능력에서 유아의 자아존중감이 향상되었고, 유아개인별 자아존중감 변화추이에서 향상되는 변화를 보였다. 또한, 부적응 행동유아의 친사회적 행동 변화양상은 나누기, 도와주기, 협동하기 등 친사회적 행동이 향상되었고, 유아개인별 친사회적 행동 변화추이에서 향상되는 변화를 보여주었다. The purpose of this study is to investigate the self-esteem and pro-sociality of the maladjusted children and this study is synthetic with using quantitative research. This study is made to present the possibility of the play with sand box to be the basic material for building children’s personality. For this purpose, the practical case has been analyzed to understand the effect on children’s sociality and self-esteem, as well as the way of expression of themselves and the opportunity of concentration on themselves. The target of the researcher is the 5~6 year old children in N child-care center which is attached to welfare facility in J area in Busan. The children are distracted, disturb others and have difficulty of social management, revealing the problem with a external maladjustment and their low self-esteem. Their home backgrounds are also normal except for one child whose parents are divorced. The research has been made in a daily life without any variable factor. The period of this research is 25 weeks, from August 16, 2006 to February 16, 2007 and pre examination, processing program, post examination are operated in order. As qualitative study, Young sook Kim’s modification on the Pictorial Scale of Perceived Competence and Social Acceptance for Young Children by Harter and Pike were used. In addition, Won young Lee’s revision and its questionnaire paper and assist material on the "Skill Situation Measues" by Mcginnis and Goldstein were used as measuring tool of pro-sociable behavior. For qualitative analysis tools used for this study are as follows. The results of this study were as follows: First, there was an improvement of self-esteem in cognitive ability of the children which is one of the sub factors and difference in each children who played with sand box. Second, there was an improvement of pro-sociality in sharing, help, and collaboration and it was shown in each children who played with sand box. And there was a change in children's pro-Behavior.

대전시 노은 도매시장 채소류의 농약 잔류 실태 및 식이섭취량 추정

한국탁,이규승,이은경,이용재,고광용,원동준,이정원,권순덕 한국환경농학회 2003 한국환경농학회지 Vol.22 No.3

대전시 노은 도매시장에서 채취한 6종의 채소류 중 농약잔류량을 조사한 후 이에 대한 위해성 평가를 실시하였다. 전체 100건의 분석시료 중 농약이 검출된 시료의 비율은 46.0%이었고, 잔류허용기준 초과비율은 6.0% 이었다. 검출비율이 높은 시료는 상추(85.0%), 깻잎(80.0%), 오이(60.0%) 순이었고, 상추 3건, 깻잎 3건이 허용기준을 초과하였다. 살균제는 dicar-boximide계, 유기염소계, azole계 농약, 살충제는 유기인계, 합성 pyrethroid계 농약이 많이 검출되었다. 검출빈도가 높은 성분은 procymidone, chlorpyrifos, chlorothalonil, cypermethrin, EPN의 순이었다. 위해성을 평가하기 위해서 각 농작물에 대한 농약의 추정 섭취량과 ADI를 비교한 결과, 허용기준을 초과한 깻잎의 bitertanol, triflumizole, iprobenphos가 다른 성분에 비하여 높은 비율을 보였다. 그러나 각 농산물의 식이섭취량이 적어 ADI에 대한 추정섭취량의 비율이 0.46%이하로 나타나 그 영향이 매우 낮은 것으로 판단되었다. Pesticide residues in some vegetables collected at Noeun wholesale market in Daejeon were surveyed and assessed their risk In 100 samples, the detection rate of pesticide was 46.0% and the rate exceed MRL was 6.0%. Commodities showing high detection rate were lettuce(85.0%), perilla leaf(80.0%) and cucumber(60.0%). Dicarboximide, organochlorine, and azole fungicides and organophosphorus and pyrethroid insecticides were detected. Detection frequency of pesticide was in the order of procymidone, chlorpyrifos, chlerothalonil, cypermethrin and EPN. When the estimated intake amount of the pesticides were compared with ADI to assess their risk, bitertanol, triflumizole and iprobenphos in perilla leaf were higher rate than the other vegetables. However the total amounts of intake of pesticides were estimated to less than 0.46% of ADI.

관동맥질환에서 저밀도 지단백 입자 크기의 분포

임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

하루 콩단백질 25g 섭취를 위한 메뉴작성 및 영양성분 분석

한재숙,김정애,서봉순,이연정,서향순,조연숙,한경필,이신정,오옥희,우경자,조은자,구성자,김수진,李承彦,南出隆久 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.2

The purpose of this study was to develop menus for daily intake of 25g soybean protein and to analyse nutrients of these foods. Analytical values were compared to the theoretical one using the food composition table and recommended dietary allowances for Koreans (7th revision). The results are as follows. 1. Soybean curd residue stew, Soybean curd, Kimchi saute, and hard boiled soybean and lotus root were selected for the menu for January, of which the content of soy bean protein(SBP) was 33.1g, soybean stew, soybean curd and soybean sprout saute, and Italian deep fried soybean curd were for February, of which the content of SBP was 35.0g. The content of SBP in soybean paste soup with soybean curd, fried soybean curd and fried soybean curd roll, the menu for March, was 24.9g. That of April were soybean curd gratin with soymilk, soybean curd and ham with garlic dressing and the content of SBP was 26.3g. That of May were soybean porridge, soybean flour cake with honey (Dasik), soybean sprout soup and the content of SBP was 26.7g. That of June were soymilk, pan-fried soybean curd, steamed soybean curd with chicken and the content of SBP was 28.4g. That of July were noodle with soymilk, mapatofu, soybean curd salad and the content of SBP was 24.7g. That of August were soybean sprout with mustard dressing, Tossed green pepper with raw soybean flour, Tofu and Kimchi stew, soybean curd steak and the content of SBP was 26.2g. That of September were Chinese cabbage soup with raw soybean flour, sweet and sour tofu and the content of SBP was 23.2g. That of Oct. were Fermented soybean stew, soybean pan cake and the content of SBP was 24.3g. That of November were not-pressed soybean curd casserole, pan-fried mashed soybean curd with egg, stir frying deep-fried soybean curd with vegetables and the content of SBP was 22.4g. That of December were soybean curd and mushroom casserole, fried soybean curd and vegetables, hard boiled soybean curd and the content of SBP was 28.9g. 2. The ratio of the analytical value over theoretical value (A/B%) of one serving in kcal, carbohydrate, protein, fat, ash and dietary fiber were 57.7~107.7%, 42.9~131.9%, 79.2~118.3%, 54.5~100%, 40.7~80.8% and 42.1~113.2%, respectively. 3. The ratio of A/B% of one serving in Ca, K, Na, P and Fe were 44.1~93.6%, 59.0~153.1%, 53.1~117.7% 64.6%~138.8 and 33.8~77.3%, respectively. That in Fe was the lowest among minerals. 4. The ratio of analytical value over Korean R.D.A(A/C%) in Ca was relatively higher (22.0~85.9%) than that in kcal(18~63%). 5. The ratio of A/C% in Fe was 25.1~64.3% and lower than that in Ca and protein in general.

에어로빅 운동시 의복조건에 따른 인체생리반응과 의복기후에 관한 연구

이원자,박승순,김은주 건국대학교 생활문화연구소 1995 생활문화ㆍ예술논집 Vol.18 No.-

In this study, an experiment was made with the wear of aerobics dress made of cotton 42%/polyurethan 8%/acrylic 50%(C/PU/AC) being marketed under the conditions of temperature at 17 ±2℃, humidity at 65 ±5%(R. H) and air current at 0.25 ±1.0m2/sec at the winter room en- vironment in an attempt to analyse the physiolosical response of the human body, the temperature inside the dress and subjective wear sensation in accordance with the wear area and the presence of underpants wear. As for the skin temperature,the exerciser was shown to have a higher skin temperature in regions exepted forearm and abdomen after exercise than the non-execiser in case of short-sleeve, while it was shown that the exciser had a higher skin temperature in regions except forearm than the non-exerciser in case of long-sleeve. It was found that the amount of sweating was higher in case of long sleeve wear than that in case of short sleeve wear, and that the exerciser had a higher amount of sweating than the non-ex- erciser. There was not a significant difference in blood pressure and pulse. In the physiological response of the human body and clothing climate in accordance with whether the underpants are worn or not, it was shown that the skin temperature was high in such regions as the breast, the thigh and the abdomen in case the underpants were worn in relation to the skin temperature, and it was shown to be find to be low in regions such as forearm and forehead. It was found that the amount of sweating was the greater in case of the underpants were worn than in case of the pants were not worn. There was not a significant difference in blood pressure and pulse.

트리스디에틸아미노수소화알루미늄 리튬의 합성과 환원특성

이재철,박기석,차진순,정승원 嶺南大學校附設 基礎科學硏究所 1988 基礎科學硏究 Vol.8 No.-

The stoichiometries and approximate rates on the reaction of representative organic compounds with a new reducing agent, lithium tris(diethylamino)aluminum hydride (LTDEA), prepared from the reaction of lithium aluminum hydride and 3 equivdiethylamine, have been examined systematically under the standardized conditions(THF,0℃) in order to characterize its reducing power. The introduction of dialkylamino group to LiAIH₄modifies the reducing characteristics of parent hydride. The reagent appears to be a mild, selective reducing agent. Especially, the reagent shows the possibility to reduce carboxylic acids, esters, amides, and nitriles. If the full scope of the reducing characteristics of this reagent has been completed, the utility in organic synthesis should be widely spread.

하치조신경 및 설신경 손상 평가를 위한 한국인 정상 성인의 하순-이부 및 혀의 감각 조사

이종호,이세영,송승일,이은진,안강민,김성민,명훈,황순정,서병무,최진영,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

In the head and neck area, there are so many sensory nerves, which are sometimes injuried iatrogenically or inadvertently so that involved patients complained of the loss of sensations. In such cases, it is important to judge the degree of injuries and regeneration of nerve for better diagnosis and treatment. Seddon and Sunderland's classification, which is commomly used, is focused on histological change and nerve conduction. As times goes by, it is difficult to access patient's sensory disturbance by this method. Until now, so many methods such as contract threshold, direction, two-point discrimination, pin prick, thermal discrimination and current perception threshold have been introduced for sensory evaluation. However, there hasn't been enough information regarding each methodology nor integrated standard methodology for the measurement. the purpose of this study is to get Korean adult normative sensory values of lower lip,chin and tongue using modified methods of contact thershold, ditection, two point discrimination, pin prick, thermal discrimination and assess degree of regeneration of sensory nerve damage.