심실전도장애환자에서 위상각 분석의 의의

전은석,곽병수,이강욱,박종훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

It is known that the normal His-Purkinje system provides for nearly synchronous activation of the right and left ventricles. When this His-Purkinje conduction is abnormal, the resulting sequence of the both ventricular contraction should be changed. These abnormal mechanical consequences resulting from abnormal conduction system have been difficult to demonstrate because these are very rapid and complex. We evaluate the phase angle analysis using radionuclide gated blood pool scan(GBP) as a quantitative method which can determine the asynchronous contraction of left ventricule in patients with complete left bundle branch block(C-LBBB, 20 cases) and complete right bundle branch block(C-RBBB, 15 cases). The results as follows : 1) The ejection fractions, peak ejection rates, in GBP were significantly decraesed in patients with C-LBBB compared with controls(10 cases, 70± 4.2 vs 44± 13.9%, 3.51± 0.62 vs 2.48± 0.98, p<0.05 by t-test respectively). The peak filling rates were also decreased in patients with C-LBBB(3.38± 0.92 vs 1.76± 0.71, 1A.05). 2) In the phase angle analysis, the standard deviations and the width of half maximum of phase angle were significantly increased in patients with C-LBBB(8.6± 1.8 vs 20.6± 18.1, 16.0± 3.9 vs 22.5± 9.2, p<0.05 by t-test respectively). And the ranges of phase angle were also increased in C-LBBB(51.3± 5.4 vs 95.7± 31.7, p<0.05). 3) But there were no significant differences in GBP and phase angle analysis between patients with C-RBBB and controls. As the results above, it can be concluded that the phase angle analysis can provide an accurate noninvasive method to detect the asynchronous contraction in patients with abnormal intraventricular electrical activation.

관상동맥질환에서 Tc-99m Methoxyisobutyl Isonitrile (MIBI) Myocardial SPECT의 이용 : Dipyridamole 심근부하 SPECT와 관상동맥조영술과의 비교 A Comparison between Coronary Angiography and Tc-99m-MIBI Myocardial SPECT

이강욱,전은석,박종훈,신영태,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

In order to evaluate clinical utilities of Tc-99m MIBI dipyridamole stress myocardial SPECT in patients with coronary artery disease (CAD), we compaired tomographic and polar map images of Tc-99m MIBI myocardial SPECT with the results of coronary angiography in 25 patients with CAD (myocardial infarction 13,angina pectoris 12) in Chungnam National University Hospital from Oct. 1991 to Oct 1993. Percutaneous transcoronary angioplasty (PTCA) was done in three patients of 25 CAD patients and follow up SPECT studies were done in same three patients within 2 months after PTCA. The results were as follows : 1. Mean age of patients was 57.4 years. Man was 2.7 times more than woman. 2. Sensitivity and specificity of Tc-99m MIBI myocardial SPECT for the detection of coronary artery stenosis in patients with myocardial infarction were 92.7 % anf 85 %, respectively. 3. Sensitivity and specificity of Tc-99m MIBI myocardial SPECT for the detection of coronary artery stenosis in patients with angina pectoris were 100 % and 67 %, respectively. 4. After PTCA size of perfusion defects in stress SPELT images was decreased in all three patients . With the results above,we thought that Tc-99m MIBI myocardial SPECT is useful noninvasive method to detect stenosed coronary artery in patients with CAD and it can be used as a method to evaluate the result of PTCA.

중이수술시 일측성 고삭신경 손상 후 미각변화

조양선,정유석,강수미,동헌종 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.2

과학 영재를 위한 캠프 운영과 교육 프로그램의 개발 준거

여상인,노석구,강호감,이희순,홍석인,송상헌,정동권 인천교육대학교 과학교육연구소 2003 과학교육논총 Vol.15 No.-

본 연구는 영재 프로그램과 그 운영의 적절성과 타당성을 판단하는데 기초 자료가 될 수 있는 준거를 추출하기 위한 연구이다. 과학캠프 활동 프로그램에 대한 학생들의 흥미와 유익성, 영재캠프 운영에 관련된 문항으로 구성된 설문지를 캠프에 참가한 학생과 그 학부모에게 실시하여 분석하였다. 영재 캠프에 참가한 학생은 직접 참여할 수 있으면서 지적 호기심을 자극하는 활동에 흥미를 느꼈고, 놀이 요소가 포함된 프로그램을 많이 선호하였다. 학생들이 모르거나, 중요하다고 생각하거나, 일상생활에 적용할 수 있는 과학 지식이나 원리를 배웠다고 인식하는 경우, 유익한 프로그램으로 인식하였다. 과학 영재 캠프의 운영에 있어서 많은 학생이 방학 중에 1주일 정도의 기간으로 합숙하는 프로그램 운영 방식을 선호하였다. 이러한 연구 결과를 토대로 본 연구에서는 캠프 활동 프로그램과 운영에 대한 몇 가지 시사점을 제안하였다. This study is to find out criteria and basic data to evaluate effectiveness and validity of program for gifted children in science. To this purpose, a questionnaire to investigate the perception of interest and usefulness for camp activities was administered to the gifted children registered to science camp. By analyzing their responses, we could conclude that the gifted children thought the activities, which stimulating their curiosity or providing opportunities to participate, to be interesting to them. They preferred the activities like a play or a game and considered that a useful activities should have something worth-learning. They and their parents preferred to stay in a camp for a week. Based on this research, we suggested some implications about academic camp program for gifted children in science.

전국 응급의학과 수련병원의 응급실 병력지에 대한 분석

임태호,임훈,이종호,강형구,장문준,조광현,장석준,김승호,정상원 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: This study was designed to analyze the current emergency department(ED) medical records of teaching hospitals in Korea. Methods: The five-item questionnaires were mailed to the EDs of 40 hospitals. Among them, 27 questionnaires and 35 ED medical records were returned for reply rates of 67.5% and 87.5%, respectively. Results: 1) The actual number of data elements in the ED medical records used by each hospital varies widely. It ranges from 1 to 15 data elements with an average of 7.5 data elements. 2) Thirteen data elements, signature of nurse, checklist style in review of systems, checklist style in physical examination, neurologic examination, figure of face, Glasgow coma scale, trauma scale, treatment plan, mode of transfer, condition on transfer, documents sent with patient, condition on discharge or discharge instruction, use of pediatric chart and vaccination history are used by less than 50% of the medical records examined. 3) There was no difference in the total number of data elements or in redesign and computerization of ED medical record based on the location of the hospital, the type of hospital administration, or the number of years since the start of EM residency program. 4) There was a statistically increased number of data elements in redesigned medical records. 5) In the survey, 89% of the residents replied that medical records needed to be redesigned. With respect to uniformity, 58% of the residents disagreed. A well-designed checklist chart rather than a descriptive chart was preferred by 89% of the residents. Conclusion: The currently used ED medical records have much room for improvement. The age of the ED had little impact on the quality of ED medical records. More attention and effort in this field are needed. In addition, The Korean Society of Emergency Medicine should provide guidelines for ED medical records.

개선된 다출력 동적 CMOS 설계 방식을 이용한 고성능 32 비트 CLA가산기 설계 및 구현

송근호,방만식,서정훈,한석붕,이효상,김강철 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

In this paper, we designed, implemented and evaluated 32-bit CLA adder with the ENMODL(enhanced NORA Multiple Output Domino Logic) logic style which is new dynamic CMOS logic. The circuit is implemented using 0.8㎛ CMOS double-metal process technology. It operates stably and the addition time is less 3.9 ns. The ENMODL logic style can improve the performance in the high-speed computing circuits depending on the degree of recurrence.

고빌리루빈혈증을 동반한 자가면역성 간염 1례

서영범,김성욱,장재식,강혁주,이중현,윤병구,김욱년,이광헌,이구,유석동,양창헌,이정호,이영현,이창우,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

자가면역성 간염은 대개 만성 경과를 가지며, 혈중 자가면역항체와 혈청 글로불린치의 상승, 그리고 조직학적으로 괴사 염증성 변화를 특징으로 하는 질환으로 아직 정확한 병인이 밝혀져 있지 않은 상태이다. 발병연령은 대개 젊은 영자(15-25세)에서 호발한다. 이 질환은 급성 간염의 임상경과를 보일 수 있으나, 심한 급성 간염이나 전격성 간염으로도 나타날 수 있는데, 이 경우 아주 나쁜 예후를 보인다고 한다. 치료는 자가면역성 간염 임상 경과의 다양성이나 병인, 병리기전의 불확실성에도 불구하고 대개 steroid 치료에 반응하는 것으로 알려져 있으며 대개 80%의 관해율을 나타내며 궁극적으로 간경변으로의 진행을 막을 수 있는 것으로 보인다. 저자들은 58세 남자에서 발생한 급성의 경과를 가지고 심한 황달을 동반한 자가면역성 간염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and a high serum globulin level. The age of onset of AIH show a peak between the age of 15 and 25 years. AIH can develop and be manifested as acute hepatitis, but severe form of acute hepatitis or fulminant hepatic failure has a poor prognosis. Although AIH is likely to progress from chronic active hepatitis to cirrhosis, steroid therapy can control the disease activity, prolong survival, improve the quality of life , and defer liver transplantation. In the present report we describe a 58-year-old man who admitted because of progressive jaundice and fatigue. He was diagnosed with AIH from laboratory test result showing positivity for antinuclear antibodies, anti-smooth muscle antibodies, and negativity for hepatitis viral markers and from liver biopsy. Steroid therapy, oral administration of prednisolone, was effective in improving the liver function test. Following liver biopsy 6 months after onset shows markedly improved necroinflammatory activity.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Effects of Black Solider Fly Larvae (Hermetia illucens L.) Powder adding to Emulsion-Type Chicken Breast Sausages on Quality Properties

Hun-Seok Kang,Jun-Hyuk Boo,Ji-Yeon Chun 한국식품영양과학회 2022 한국식품영양과학회 학술대회발표집 Vol.2022 No.10

Contribution of Marine Microbes to Particulate Organic Matter in the Korea Strait

Kang, Hun,Kang, Dae-Seok The Korean Society of Oceanography 2002 Journal of the Korean Society of Oceanography Vol.37 No.1

To assess the relative contribution of bacterial and phytoplankton biomasses to particulate organic matter (POM) in the water column, microbial abundance and biomass were from two transects in the western channel of the Korea Strait in 1996. Bacterial abundance had a mean value of $5.9{\times}10^5$ cells/ml and chlorophyll-a averaged 0.14 ${\mu}g/l$. Bacterial abundance in the Korea Strait showed a positive relationship with chlorophyll-a concentration, while the distribution of POM did not covary with chlorophyll-a. Particulate organic carbon (POC) and nitrogen (PON) concentrations were greater in August than in October. Bacterial carbon (POC) and nitrogen (PON) concentrations were greater in August than in October. Bacterial carbon and nitrogen biomasses were 7.29 ${\mu}gC/l$ and 1.24 ${\mu}gN/l$, respectively, during the study periods. Bacterial biomass was larger in October than in August due to the autumn phytoplankton bloom. Phytoplankton biomass based on chlorophyll-a was 7.67 ${\mu}gC/l$ for carbon and 1.10${\mu}gN/l$l for nitrogen. The ratio of bacterial carbon (BC) to phytoplankton carbon (Cp) averaged 0.95 in the Korea Strait in 1996. Bacteria may play a more significant role in the dynamics of POM than phytoplankton do in August, with BC/Cp ratio of 1.26. The ratio of BC to Cp increased with a decrease in chlorophyll-a concentration. Averaged over all the samples in both cruises, the contribution of microbial biomass to POC and PON was about 43% and 51%, respectively. Bacterial assemblage constituted a significant fraction of POC (21%) and PON (27%). Phytoplankton accounted for 22% of POC and 24% of PON. Microbial biomass played a more important role in the dynamics of POC and PON in October than in August due to a significant increase in microbial biomass in the southern transect (transect-B) in October by the autumn phytoplankton bloom. This study showed that marine microbes may constitute a significant part in the reservoir of POM in the Korea Strait.