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Renal cell carcinoma metastasis to the parotid gland after tumor nephrectomy is extremely rare. We report a case of solitary parotid metastasis from clear cell renal cell carcinoma in a 64-year-old man, who presented it 10 years after primary treatment. Superficial parotidectomy and deep lobe mass removal with preservation of the facial nerve was performed. The patient is currently being followed up regularly with no additional metastasis observed for 13 months.
This study examined the causes and epidemiologic factors of smell loss in Koreans using the Korean Version of the Sniffin’ Sticks Test and compared the results with cases of foreign countries. Subjects and Method:The data of 386 patients who visited clinics complaining of smell loss were retrospectively analyzed with medical charts. Results: Idiopathic, upper respiratory tract infection, trauma, nasal and paranasal sinus disease were the major causes of smell loss in this study. The distribution of gender and age, severity of smell loss, association of smell loss with allergies and nasal polyps were discussed in detail. Conclusion:The proportion of each cause observed in this study was different compared with the results of other domestic reports of nasal and paranasal sinus disease, but came out similar to the results of foreign studies. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:717-21)
Reticulohistiocytosis represents a rare spectrum of non-Langerhans cell histiocytosis:the solitary cutaneous form (reticulohistiocytoma), the diffuse cutaneous form without systemic involvement, and multicentric reticulohistiocytosis with systemic involvement. We report a case of solitary cutaneous reticulohistiocytosis in a 46-years-old male, who presented with an asymptomatic firm, dome-shaped nodule on the right vestibule of nose. The lesion was completely excised and no evidence of recurrence was observed. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:484-6)
This study investigated the surgical methods and their results according to the subtypes of zygomatic fractures. Subjects and Method:Medical records of 99 zygomatic fractures treated between March 1997 and December 2006 were reviewed regarding fracture type, surgical method and time of operation from the initial trauma. Results:Overall, operations were performed in 70 out of 99 cases. For zygomatic arch fractures, facial asymmetry and trismus in all 14 of 20 cases after surgery by Gillies incision were improved, and one revision procedure was performed. For tetrapod and multifragment fractures, one revision procedure was performed because of displacement of repaired bone fragment following surgery in 60 cases. Considering location and replacement of fractures, surgery was performed through one of incisions below:Gillies, lateral canthal, gingivobuccal, and subcilliary incision. All preoperative symptoms were improved. Conclusion:For zygomatic arch fractures, Gillies approach would be an optimal method, while for displaced tetrapod and multifragment fractures, two or more point fixation points would achieve satisfactory results. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:326-30)
Reports of neural differentiation of mesenchymal stem cells suggest the possibility that these cells may serve as a source for stem cell-based regenerative medicine to treat neurological disorders. The purpose of this study was to generate neural cells by differentiation of bone marrow-derived mesenchymal stem cells that isolated from human mastoid process. Materials and Method:Human mesenchymal stem cells (hMSCs) isolated from human mastoid process bone marrow during mastoidectomy for chronic otitis media surgery were characterized using fluorescence-activated cell sorter. Induction of neural differentiation from hMSCs was performed using mitogenic factors (basic fibroblast growth factor, epidermal growth factor, forskolin, isobutylmethylxanthine), and the characterization of differentiated hMSCs was performed using immunohistochemistry, RT-PCR and whole cell patch clamp technique. Results:hMSCs from bone marrow of mastoid process were isolated and cultured. Differentiated cells from hMSCs expressed mRNA transcripts for neuron specific markers, TUJ1 and neurofilament proteins (NF-L, NF-M) as determined by RT-PCR, and neuron specific markers, suhc as NeuN, TUJ1, microtubule- associated protein-2 (MAP2) and glial fibrillary acidic protein by immunohistochemistry. These cells showed voltagedependent sodium currents that was blocked by tetrodotoxin. Conclusion:hMSCs, which were isolated from human mastoid process bone marrow, were one of the good sources for stem cell-based regenerative medicine to treat neurological disorders. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:422-8)
Thymic carcinoma is a rare tumor that develops in the anterosuperior mediastinum. The prognosis of thymic carcinoma is poor. It is often misdiagnosed as a thyroid tumor in the fine needle aspiration cytology because of its rarity and non-organotypic cytoarchitectural structure. We have experienced a case of thymic carcinoma that was misdiagnosed as a thyroid carcinoma in showed a huge mas, and we suposed a malignant thyroid tumor from lower pole of the thyroid, which extended toward the superior mediastinum. The fine needle aspiration cytologic diagnosis of the mas showed that it was anaplastic carcinoma of the thyroid. Total thyroidectomy including mas and selective neck disection was performed. Postoperative pathologic diagnosis was squamous cell carcinoma of the thymus. So we report this case with a review of literature. Head Neck Surg 2007 ;50 :1179-83)
This study aims to investigate the development of open-set speech perception abilities in children who received cochlear implantation at older age and to examine the preoperative variables contributing to the postoperative speech perception outcomes. Subjects and Method:Open-set speech perception abilities were assessed with the Monosyllabic Word and Common Phrases Tests for 37 prelingually deafened children who received implantation between the ages of 7 and 17 years. Their performance was compared to that of 60 children who received implantation before 7 years of age. To identify the factors contributing to the postoperative open-set speech perception abilities, we analyzed age at hearing aid fitting, age at implantation, duration of implant use, preoperative language and speech perception abilities, and pure tone thresholds in the better ear. Results: The children who received implantation after 7 years of age significantly improved during the first year of implant use, but reached a plateau by 1.5 to 2 years after implantation, reaching scores between 60% and 70%. Children who received implantation after age 7 showed higher speech perception scores than the younger children over the first year of implant use, but showed lower scores than the younger children after 2-3 years of implant use. The variables associated with the postoperative open-set speech perception abilities were speech perception ability, language ability, and hearing levels before implantation. Conclusion:Prelingually deafened children who received implantation at older age can obtain substantial open-set speech perception understanding, but tended to reach a plateau between 1.5-2 years after implantation. Speech perception, language abilities, and hearing level before implantation contribute to the outcome. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:130-5)