손상모에 대한 클리닉 전,후의 모표피와 커트후의 절단면 비교

정인복 ( In Bok Jeoung ),이주영 ( Ju Young Lee ) 한국미용학회 2008 한국미용학회지 Vol.14 No.2

This thesis was intended to examine the hair cuticle and cross section regarding the damaged hair due to damages from chemical treatment during hair styling, in other words protein denaturation by chemicals or heat, and delamination or falling off of cuticle layer among hair damages. A total of 8 women in their 40`s were selected as study subjects where 6 hair pieces were made for each for a total of 48 used. Each piece was damaged artificially after which hair cuticles before & after clinical treatment and cross sections of blunt and notching cuts were observed under electronic microscope (SEM). First, as a result of observing the condition of cuticles, before clinical treatment, they were loose with cornifications, bubbles and hardening phenomenon, even melted down or had holes. After clinical treatment, however, supply of oil & moisture made them smooth with substantial lessening of cornification and hardening as well as cuticular markings maintaining stable form. Second, by comparing the cross section in the case of cutting, before clinical treatment, the edges of cross section were filthy with marked delamination of cuticle and cortex layers, there were also breaking of cortex layer thus even showing signs of Trichorrhexis Nodosa. Nevertheless, after treatment, there were relatively clean cross section and edges, breaking of cortex layer was nearly non-existent and delamination was also much lessened thus showing greatly reduced damage.

전기경련치료의 마취를 위한 실제적 문제들

윤탁,김용식,이남영,김세현,최준권,이정혁,정인원,Youn, Tak,Kim, Yong Sik,Lee, Nam Young,Kim, Se Hyun,Choi, Jun Gwon,Lee, Jeoung Hyuk,Chung, In Won 대한생물정신의학회 2017 생물정신의학 Vol.24 No.3

Electroconvulsive therapy (ECT) has been recognized effective as primary or secondary treatments for major psychiatric disorders including depression and schizophrenia, as well as psychiatric emergency such as suicide, food refusal and catatonia, and so on. Medicines used in anesthetic induction for ECT, cause various reactions in autonomous, hemodynamic, and neuromuscular systems. The anesthetics also affect the duration, threshold, and intensity of seizures evoked with electric stimuli, and thus modify the seizure quality in ECT. Individual characteristics of age, sex, weight, comorbid physical disorders, and medications should also be considered for optimal clinical response after ECT. When preparing for anesthesia, adequate anesthetic agents and muscle relaxants, and rapid recovery should be carefully considered. We conducted a case-series study to address practical issues that are frequently encountered during ECT anesthesia with reviews of updated journals in order to provide practical helps to clinicians who are preparing ECT for their patients.

원저 : 한국 여성에서 우울증상과 대사증후군의 관련성

윤대현 ( Dae Hyun Yoon ),박진호 ( Jin Ho Park ),조수철 ( Soo Churl Cho ),박민정 ( Min Jeoung Park ),김선신 ( Sun Sin Kim ),최승호 ( Seung Ho Choi ),최수연 ( Su Yeon Choi ),정인경 ( In Kyong Jeong ),이철민 ( Cheol Min Lee ),신찬수 대한비만학회 2005 The Korean journal of obesity Vol.14 No.4

연구배경: 우울증은 여성에서 유병률이 높고 다양한 질환과의 연관성을 보이는데 특히 심혈관계 질환과의 상호 연관성이 보고 되고 있다. 대사증후군 또한 만성 질환 발생에 매우 주요한 위험인자로 그 중요성이 강조되고 있는데 아직 우울증과 대사증후군의 연관성 연구는 제한된 연령의 여성군에서만 소수 진행되었다. 본 연구는 광범위한 연령의 여성을 대상으로 우울증상과 대상증후군의 연관성을 분석해 보고자 한다. 방법: 연구대상자는 15~85세 사이의 여성 4,613명이었다. 대사증후군 존재 유무 평가는 복부미만을 제외하고는 NECP-ATP III 기준을 활용하였고 복부비만의 평가는 최근 제안된 대한비만학회의 새로운 지침을 이용하였다. 우울증상은 Beck 우울 척도로 측정하였다. 결과: 연구대상자 중 594명 (12.9%)이 대사증후군을 가지고 있었다. 우울증을 가진 여성군에서 대사증후군의 존재 빈도가 유의하게 높았고 (P<0.001), 대사증후군 지표수가 증가할수록 우울증상군이 증가하는 경향을 보였다 (P<0.01). 우울증상과 대사증후군 5가지 지표들 (허리둘레, 고혈압, 중성지방, 혈당, 고밀도-콜레스테롤)의 연관성 분석에서는 혈당 상승 (P<0.05)과 복부 미만 (P<0.01)이 통계적으로 유의성을 보였다. 결론: 본 연구의 결과는 여성에서 대사증후군과 우울증 간 연관성이 존재함을 보였고 대사 증후군과 우울증의 상호 역할에 대한 보다 적극적인 이해가 필요함을 시사한다. Background: Depression is prevalent among women and has been associated with a variety of diseases, more specifically with cardiovascular disease. The metabolic syndrome is gaining reputation as an important risk factor for major chronic diseases. However, the study on relationship between depression and metabolic syndrome are scarce and have been limited to restricted age groups involving female participants. The current study examined the association between depressive symptoms and metabolic syndrome in Korean women through broad age ranges. Method: The participants included 4,615 Korean women aged 15~85 years. Each individual was assessed for the presence of metabolic syndrome according to the NECP-ATP III criteria except for waist circumference, for which new criteria recently suggested by Korean Society for Study of the Obesity was used. Depressive symptoms were assessed by Beck Depression Inventory (BDI). Results: Of the total participants, 594 women (12.9%) had metabolic syndrome. There was a graded relationship between depression and number of the metabolic syndrome components (P<0.01). The prevalence of Metabolic syndrome was significantly higher in depressed women (P<0.001). Among the components of metabolic syndrome, High glucose level (P<0.05) and central obesity (P<0.01) were associated with depressive symptoms. Conclusion: This study shows that metabolic syndrome is associated with depressed women through wide range of ages and suggests that further studies on interaction between depression and metabolic syndrome are needed.

TFT의 길이와 두께에 관한 특성

이정인(Jeoung-In Lee),황성현(Sung-hyun Hwang),정성욱(Sung-wook Jung),장경수(Kyung-Soo Jang),이광수(Kwang-Soo Lee),정호균(Ho-kyoon Chung),최병덕(Byoung-Deog Choi),이기용(Ki-Yong Lee),이준신(Jun-Sin Yi) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.10

Recently, poly-Si TFT-LCD starts to be mass produced using excimer laser annealing (ELA) poly-Si. The main reason for this is the good quality poly-Si and large area uniformity. We report the influence of channel length and width on poly -Si TFTs performance. Transfer characteristics of n-channel poly-Si thin film transistors fabricated on polycrystalline silicon (poly-Si) thin film transistors (TFTs) with various channel lengths and widths of 2-30 ㎛ has been investigated. In this paper, we analyzed the data of n -type TFTs. We studied threshold voltage (VTH), on/off current ratio (I<SUB>ON</SUB>/I<SUB>OFF</SUB>), saturation current (I<SUB>DSAT</SUB>), and transconductance (g<SUB>m</SUB>) of n-channel poly-Si thin film transistors with various channel lengths and widths.

테뷰코나졸의 제어된 전달을 위한 스마트 나노운반체

마헤시바트 ( Mahesh P. Bhat ),김정인 ( Jeoung-in Kim ),이경환 ( Kyeong-hwan Lee ) 한국농업기계학회 2022 한국농업기계학회 학술발표논문집 Vol.27 No.1

Crop failure due to pathogen infection is a common issue in agriculture that affects productivity. Metal-organic frameworks (MOFs) are a new type of porous hybrid inorganic- organic material that has potential in sustainable agriculture because of their high performance. Pesticide release that responds to environmental stimuli is highly desirable for greater effectiveness and fewer adverse effects. Because iron (Fe) is an important element for crop growth, Fe-MOFs have a promising future in agriculture as multifunctional materials for pesticide delivery and plant nutrient replenishment. In here, a octahedral MOF synthesised by green method used as delivery vehicles for the tebuconazole fungicide. The high surface area of 1005.2 m2/g could encapsulate satisfactory loading for tebuconazole up to 15.84%. Tebuconazole loaded Fe-MOF (Teb@Fe-MOF) demonstrate a pH-responsive initial burst followed by a continuous release pattern. Furthermore, Teb@Fe-MOF has strong fungicidal activity against two pathogenic fungi such as tomato early blight (Alternaria solani) and late blight (Phytophthora infestans). In addition, Fe-MOF performs as micronutrient by improving tomato plant growth. Thus, Fe-MOF found to be potential cost-effective candidate in sustainable plant protection as investigated in this study.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.