축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

Rubinstein-Tabyi syndrome에 관한 증례보고

정성호,양규호,이태희 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.1

Rubinstein-Tabyi syndrome은 드물게 나타나는 기형증후군으로 정신 발달지연, 넓은 손가락과 발가락, 작은 키, 특징적인 안모등의 증상들을 주증상으로 하는 여러 계통의 형태이상이 비 특정 양상으로 나타나는 선천적 증후군이다. 1963년 Rubinstein과 Tabyi에 의해 처음 보고된 이 증후군은 많은 연구에도 불구하고 명확한 원인이 알려져 있지 않고 있으며, 1990년 이후 Rubinstein-Tabyi syndrome에 대한 특정소인 연구에서 이 증후군의 임상적 특징을 보이는 소수의 환자에게서 16번 염색체의 16p13.3의 유전학적 단절이 보고되었다. 그러나, 이 증후군의 특정병인으로 보기는 힘들고, 여전히 이 증후군의 진단에는 특징적인 임상증상들로 인해 가능하다. 이 증후군의 치과적 증상으로는 높게 위치한 구개, 소하악증, 다발성 우식증 등이 보고되고 있다. 다발성 우식증을 주소로 내원한 6세 5개월된 남아가 넓은 엄지손가락과 발가락, 정신 및 운동발달지연과 안검하수증, 이상 형태의 귀 등을 포함하는 안면부 이상 등의 증상들을 보였다. 저자들은 환자가 보이는 특징적인 임상 증상들로 인해 Rubinstein-Tabyi syndrome으로 진단을 내리고 환자의 전신 상태를 고려하여 모든 치과 치료를 전신마취 하에 시행하였다. Rubinstein-Tabyi syndrome(RTS) is a congenital multisystem dysmorphic syndrome with many non-specific features, making diagnosis occasionally difficult. The major features of this syndrome include mental retardation, characteristic facial appearance, short stature, microcephaly, and broad thumbs and halluces. This syndrome was first described by Rubinstein and Tabyi in 1963, and many studies have been continued about this syndrome, but specific pathogenesis of the Rubinstein-Tabyi syndrome phenotype is still not clear. High arched palate, micrognathia and multiple caries etc have been reported in Rubinstein-Tabyi syndrome. In this report, a 6-year and 5-month-old boy visited at our department due to multiple dental caries, who showed broad thumbs, mental and physical development retardation, and characteristic facial appearance including both ptosis and ear deformity. This patient was diagnosed as a Rubinstein-Tabyi syndrome, and treated the multiple dental caries under general anesthesia. This study was aimed to observe the relationship between medical and dental characteristics.

1,2-Benzisothiazol-3-one-1,1-Dioxide 유도체의 합성

정대일,정희철,변석인,이용균,박유미,최순규,한정태 東亞大學校附設基礎科學硏究所 2002 基礎科學硏究論文集 Vol.19 No.1

사카린 유도체는 제초제, 항독성, 살균제 등에 광범위하게 연구되어져 오고 있다. 새로운 농략 활성을 가진 물질을 합성하기 위해 먼저 선도물질로 사카린 1을 산화, 염소화 시킨 3-chloro-1,2-benzisothiazol-1,1-dioxide(BID-CI) 2와2cholromethy-1,2-benzisohizol-3-one1,1-dioxide 4를 합성하였다. 선도물질, amines, imidazoles, trones등과 반응시켜 다음과 같은 물질들을 얻었다. ; 3-cyclohexylamino-1,2-benzisothiazol-1,1-dioxide 6, 3-furylamino-1,2-benzisothiazol-1,1-dioxide 8, 3-(3-imidazol)-1,2-benzisothiazol-1,1-dioxide 10, 3-(2-methy-3-imidazol)-1,2-benzisothaizol-1,1-dioxide 12, 2-(3-imidazol)methy-1-1,2-benzisothiazol-3-one-1,1-dioxide 13, and 2-(-3-imidazol)methyl- 1,2-benzisothiazol-1,1-dioxide 14.

사상공업지역의 환경과 재개발에 관한 기업주의 의식분석

정헌영,김태규 釜山大學校 都市問題硏究所 1996 都市硏究報 Vol.4 No.-

Sasang Industrial Complex and hinter-residential areas caused some problems related to the infrastructures and environmental pollution in lack of some considerations from the land subdivision project. According to the Pusan Urban Masterplan(1992) and the Pusan-Kyungnam Metropolitan Development Plan(1995), then, the surveyed area will be redeveloped to the western core of the Pusan Metropolitan City and attracted to the mixed land-use complex with the commercial and distribution function, including the electricity, shoes, leports, and clothes wholesales. This results of the survey found that most subjects considered the environmental pollution as serious and the unsatisfactory factors were as follows: traffic jam and air pollution. According to whether you know the Complex Transferred Plan, 34.9% of them was responded to "yes" and the rest to "no". This finding means that the area is environmentally bad condition in terms of the transportation and infrastructures, however, most subjects were satisfied with the location because of easy access to the CBD. The results also suggested that the redevelopment of the area is needed and the way is mainly based on the individual improved construction.

남자 초·중학생의 무산소성 작업능력과 무산소성 파워의 관계

정동식,정덕조,정성태,이병근,전태원,김은혜,이동규,정동춘 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.2

The critical power(CP) is the highest intensity to sustain for a long time without a fatigue. The anaerobic work capacity(AWC) is the highest anaerobic capacity to be provided by anaerobic energy system without the infection of hypoxia. The purpose of this study was to determine the relationship between AWC and AnP and to verify the validity of AWC. The subjects were consisted of 10 elementary and 10 middle school male students(12.8±1.3yrs, 159.3±12.1㎝, 49.4±11.8㎏). The critical power and anaerobic work capacity were calculated by work-time relationship after four cycle ergometry test to fatigue from 1 to 10 minute. The anaerobic power included Margaria-Kalmen test, Sargent jump and Wingate test. The main finding were as follows. The AWC of elementary and middle school students. were 6.47±2.63KJ and 11.10±3.01KJ. The AWC of elementary students was 58.3% of the middle school students's one. The AnP of elementary students were 47.2∼66.5% of the middle school students's one. And there were high correlation between AWC and AnP(0.64∼0.87, P<0.01). This study showed that AWC is useful index on AnP both elementary and middle school students.

비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정

서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.

혐기성 유동상법에 의한 축산폐수의 처리

엄태규,임정원 慶星大學校 環境問題硏究所 1996 環境硏報 Vol.6 No.1

The treatment of livestock-wastewater have to considered because of composition of livestock-wastewater is high-concentration organic matter, ammonia nitrogen. In this research, substrate to the reactor was synthetic on the basis of livestock-wastewater through the experiments. The experiments was carried out to study the characteristics of organic matter removal, the change of VFA production, and the amount of gas production, influence on bacterial activity in the reactor with respect to the change of COD loading rate using anaerobic fluidized bed, which is an anaerobic biofilm process. To analysis, the HRT and operation temperature, ammonia nitrogen concentration were 1 day and 35±1℃, 3000㎎/ℓ, respectively. It was operated by COD loading rate both 10 kgCOD/㎥·day and 20 kgCOD/㎥·day. The results obtained were as follows; According to pH, COD removal rate and glucose removal rate, the treatment efficiency was generally stable for the varing COD loading rate. Process stabilization had 20∼30 days in the early period of the operation and pH was 7.34, 7.39 at 10, 20 kgCOD/㎥·day conditions. COD removal rates were not significantly changed as values of 87%, constantly maintained. Gas productions were proportionately presented as changed COD loading rate such as values of 3700, 7400㎖/ℓ·day, respectively. Throughout the whole period of experiment, remaining VFA(as COD base) in the effluent was over 90% of remaining COD and glucose removal rate was over 99%. Thus, this result indicated that no inhibitory effect on acetogenic bacteria was almost occured.

Linear Poly(ethyleneimine)을 포함하는 루테늄 착물의 합성과 성질

박명규,한정호,조태섭 嶺南大學校基礎科學硏究所 2001 基礎科學硏究 Vol.21 No.-

Many researchers have interested ruthenium complexes due to their similarity and difference in chemical properties. In this study, [Ru(phen)_2LPEI]^2+ complex was synthesized by the reaction of [Ru(phen)_2Cl_2] with polymeric amine ligands, namely, linear poly(ethyleneimine)(LPEI). [Ru(phen)_2LPEI]^2+ complexes were analyzed by NMR, UV/VIS, and MS spectrometry. as well as Elemental analysis. From NMR analysis, [Ru(phen)_2LPEI]^2+ complexes were confirmed by comparison of [Ru(phen)_2Cl_2] with LPEI complexes. Coordination of LPEI ligands to [Ru(phen)_2Cl_2] showed absorption at 480㎚, whereas [Ru(phen)_2Cl_2] complex alone has a peak at 370㎚. Mass of LPEI complexes was analyzed 1638 and 1898 dalton, [Ru(phen)_2LPEI]^2+ complex form MS spectrometry. The spectroscopic methods for the [Ru(phen)_2LPEI]^2+ complexes system revealed that two nitrogen donor atoms on the LPEI chain are coordinated to the [Ru(phen)_2Cl_2] complex.

전기충격요법후 혈중 Prolactin에 대한 Methysergide의 영향

유태열,방승규,박원명,한진희,이수정,김광수 대한신경정신의학회 1991 신경정신의학 Vol.30 No.2

Recently it has been shown in numerous experimental studies that a series of electroconvulsive therapy(ECT) affects neurohormonal function in man, though its mechanism was yet unknown. To investigate effects of methysergide on serum prolactin response after ECT, the authors studied the change of the serum levels of prolactin before ECT(the day before ECT) and after ECT, with and without methysergide pretreatment by RIA method in 11 psychiatric patients. ECT was given with the electrodes placed in the bitemporal position using a pulse current delivering device(Thymatron). The results were as follows; 1) Compared with the day before ECT, serum prolactin levels were increased significantly at 15, 30, 60 minutes after ECT(P〈0.01). 2) Compared with ECT alone, serum prolactin levels were attenuated significantly at 15,30,60 minutes after ECT with methyserigide(P〈0.05. P〈0.01). Hormonal responses of this study in terms of the knowledge availakle on the neurotransmitter control of prolactin release suggests that the responses of prolactin to ECT may be mediated by the activation of serotonergic system in central nervous system.

결핵균 30-kDa와 32-kDa 단백항원의 분리정제와 마우스 비장세포 증식에 미치는 영향

백태현,오명주,김화중,조은경,박정규,최대경 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Identification and characterization of individual components of M.tuberculosis have long been a focus of research on tuberculosis. The 30-kDa and 32-kDa antigens are major constituents of M bovis BCG and M. tuberculosis culture fluids. Because 30-kDa and 32-kDa antigens are partially identical, these antigens are difficult to purify in large amounts by biochemical techniques. This study was performed to purify the 30-kDa and 32-kDa antigens complexes primarily purified by 50% ammonium sulfate precipitation, hydroxylapatite chromatography and Sephadex G-75 gel filtration. And then further purification for separation of the two antigens was accomplished on preparative isoelectric focusing. Recovery of 30-kDa and 32-kDa antigens during above the purification procedures were 28% and 14%, respectively, and 147.0 and 59.8-fold purification were showed, respectively. On silver stained SDS-PAGE gels, the purified 32-kDa antigen gave a single band at 32-kDa molecule, while 30-kDa antigen gave one major band at 30-kDa molecule and faint additional band at 32-kDa. The pI of 30kDa-and 32-kDa antigens were 4.3 and 4.6, respectively. The partial identity between these two antigens was observed through the same pattern of reactivity of antigens in the ELISA and precipitation pattern of immunodiffusion. We also examined the immunological activities of both purified antigens by splenocyte proliferation of BCG-infected mice. Proliferative response to the 30-kDa and 32-kDa antigens did not show significant difference. However, macrophage-like cells existed in spleen cells from BCG-infected mice were involved in the suppression of the proliferative response to mycobacterial antigen. These results suggest that the 30-kDa and 32-kDa antigens could be effectively purified by the IEF and reactions of partial identity between the two antigens were found. However, 30-kDa antigen was the more immunogenic antigen than 32-kilodalton.