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      • KCI등재후보

        원전 내 배관의 증기 누설 사고 시 누설 탐지 포집/이송 시스템 예비 해석

        최대경,최청열,권태순,어동진,Choi, Dae Kyung,Choi, Choengryul,Kwon, Tae-Soon,Euh, Dong-Jin 한국압력기기공학회 2020 한국압력기기공학회 논문집 Vol.16 No.2

        As leakage in nuclear power plants could cause a variety of problems, it is very critical to monitor leakage from the safety point of view. Accordingly, a new type of leak detection system is currently being developed and flow characteristics of the sampling and transportation system are investigated by using numerical analysis as a part of the development process in this study. The results showed that the steam mass fraction varied according to the effect of the gap between the insulation and piping component, transportation velocity, and material properties of porous media during the sampling and transportation process. The results of this study should be useful for understanding flow characteristics of the sampling and transportation system and its design and application.

      • 癩患者로 부터 癩菌檢出 方法의 改善(Ⅱ)

        崔大卿,張明雄,朴鼎圭 충남대학교 의과대학 지역사회의학연구소 1982 충남의대잡지 Vol.9 No.1

        For the improvement of detection of leprosy bacilli from patient, author's attention of the bacterial detection ratio have been devoted to compared the skin smear method with the nuclepore filter method from 200 patients who were registrated in Chungnam Skin Clinic of Korean Leprosy Association. One hundred patients out of 200 registered were positive in bacterial detection, the others were negative. For the dispersion of bacterial globi in nuclepore filter method, the skin scrapped materials were treated with 0.025% trypsin and 0. 002 % tween 80 for 30 minutes at 37℃ incubator. The efficiency of bacterial detection between the nuclepore 13 mm diameter of the filter and the 25 mm filter were investigated in the broth cultured M. fortuitum. The cultured M. fortuitum was transferedl ml into each 10 tubes, and then was carried out ten-fold dilution, respectively. The specimen for comparative counting of acid fast bacilli were made on 10^-4 dilution in using 25 mm diameter of filter and 10^-5 dilution in using 13 mm diameter of filter and cultural method. The results were summarized as follows: 1. The ratio of bacterial detection by the skin smear and nuclepore filter methods from 100 patients who were registrated with bacterial detection positive cases were not observed any difference, in all cases were detected leprosy bacilli with both methods. 2. In 100 patients who were registrated with bacterial detection negative, 19 patients were detected leprosy bacilli by the skin smear method and 33 patients were detected leprosy bacilli by the nuclepore filter method. The ratio of bacterial detection by two methods were observed statistically significant difference. (0.01<p<O. 05). 3. Between bacterial indices by skin smear and bacterial numbers of nuclepore filter methods were observed perfect positive corelation. 4. There was close corelation between 25 mm filter and the culture method, however, 13 mm filter was more higher than other two methods. From the above results, it was suggested that the nuclepore filter method with well digesting specimens with 0.025% trypsin and 0.002% tween 80 would be more accurate and higher detection ratio of M. leprae than skin smear method. The nuclepore 13mm filter was more efficient to detection of acid fast bacilli than 25 mm filter.

      • 임상실습에 임하는 학생들의 비강 및 피부에 분포된 포도구균과 환자병소에서 분리된 포도구균에 대한 병원성의 연관성에 관한 연구

        최대경,김홍선,백태현,권지순 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

        The authors have studied the pathogenecity of staphylococci isolated from 96 patients in Chungnam National University Hospital and Staphylococci isolated from nose and axilla of 50 medical and 50 nursing students in Chungnam National University. The authors conducted the survey from January 1986 to June 1986. The results obtained were as follows : 1. Out of staphylococci isolated from 96 patients, Staphylococcus aureus and Staphylococcus epidermidis were 59.4%, and 32.3%, respectively. In staphylococci isolated from nose of medical and nursing students, Staphylococcus aureus was 13.6^(male), 17.2%(female) and Staphylococcus epidermidis was 61.0%(male), 75.9%(female), respectively. 2. In the biotype of Staphylococcus epidermidis isolated from patients, the rate of biotype 1 was 93.5%. In the staphylococcus epidermidis isolated from nose of medical and nursing students, the rate of biotype 1 was 55.6%(male), 31.8%(female). In the axilla, the rate of biotype 1 was 56.5%(male), 52.6%(female), respectively. 3. In the biotype 1 of Staphylococcus epidermidis isolated from patients and control groups, enzymatic activities were more active than other biotypes. 4. Crystal violet ring test of Staphylococcus epidermidis isolated from patients, biotype 1 was WR type 22.6%, SR type 67.7% and DR type 3.2%. 5. To the antibiotic activities of staphylococci isolated from patients, Staphylococcus aureus was resistant to gentamycin(96.5%), penicillin(78.9%), lincomycin(47.4%) and erythromycine(35.1%). In the nose of medical students, Staphylococcus aureus was resistant to penicillin(11.9%), gentamycin(11.9%), lincomycin(6.8%) and tetracycline(5.1%). 6. In the multiple antibiotic resistance of staphylococci isolated from patients, Staphylococcus aureus was resistant to 2 antibiotics(35.1%), 3 antibiotics(17.5%), 5 antibiotics(15.8%) and, Staphylococcus epidermidis was resistant to 3 antibiotics(32.3%), 4 antibiotics(19.4%) and 5 antibiotics(16.1%).

      • KCI등재

        자궁외임신의 임상통계학적 고찰

        최대경,황익하,전선희,김두표,김병수,이남섭,이정래,박덕련,송희진 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.11

        1991년 1월1일부터 1994년 12월31일까지 4년간 인천 기독병원 산부인과에 자궁외임신으로 진단되어 입원 치료한 환자 120예를 대상으로 임상적 고찰을 하였던 바 다음과 같은 결과를 얻었다. 1. 총분만건 수에 대한 자궁외임신의 빈도는 1:46.1이었다. 2. 빈반연령은 25-29세의 연령군이었다. 3. 초산부는 35.0% 미산부는 32.5%였으며 대상의 73.3%가 인공유산 경험이 있었다. 4. 과거력상 가능한 유발유인을 보면 1회이상이상의 인공유산 경험이 있은 경우가 73.3%, LTS수술 13.3%, 골반염증성 질환이 9.7%의 비율로 나타났다. 5. 마지막 생리 제1일부터 증상이 나타나기까지의 기간을 보면 6-8주가 42.5%로 가장 많았다. 6. 증상에 따른 분석을 보면 하복부 동통이 93.3%에 나타났으며 질출혈이 85.8%환자에서 나타났다. 7. U-HCG test상 92.3%의양성율을 보였다. 8. 착상부위는 난관부가 96.7% 자궁각 부위에 2.5% 난소부위가 1.7%를 차지하였다. 9. 치료의 51.7%는 환측 난소 난관절제술이 차지하였으며 환측 난관절제술을 31.2%의 환자에서 시행하였다. 10. 120례 중 사망한 례는 없었다. This study was done for a clinical evaluation and statistical analysis of 120 cases who were admitted and treated at Department of Obstetrics and Gynecology, Inchon Christian hospital from January 1, 1991 to December.31 1994. The main results were as follows ; 1. The incidence of ectopic pregnancy was 1 to 46.1 deliveries. 2. The most frequent age group was in 25-29 years of ages 3. Primigravida was 11.7%, nullipara was 32.5% and 73.3% of cases have been experienced artificial abortion. 4. In the past history of possible predisposing factors, 73.3% had artificial abortions 13.3% had laparascopic tubal sterilization PID was in 9.7%. 5. THe most frequent interval between LMP and the onset of symptoms was 6-8 wks in 42.5% 6. On symptomatological analysis, low abdominal pain was encountered in 93.3%, vaginal spotting and bleeding in 85.83%. 7. Of 120 patients tested urine HCG test positive result was in 92.3%. 8. Implantated site were tubal pregnancy in 96.7% cornual pregnancy in 2.5% ovarian pregnancy in 1.7%. 9. Unilateral salpingoophorectomy was applied in 51.7% of cases for treatment and unilateral salpingectomy was in 31.2%. 10 There was no fatal case in 120 ectopic pregnancy.

      • KCI등재

        난소임신 2 예

        최대경,전선희,임경주,김두표,이남섭,이정래 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.7

        저자 등은 최근 본병원 산부인과에서 Spiegelberg의 진단기준을 충족시키는 난소임신 2예를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다. Primary ovarian pregnancy occurs within the ovary and on the corups luteum, usually with rupture of the ovary and a massive hemoperitoneum. Primary ovarian pregnancy is comparatively rare in ectopic pregnancy and the Spiegelbergs crieteria shold be fulfilled for the diagnosis of ovarian pregnancy. Two cases of primary ovarian pregnancy which have Spiegelbergs criteria for the diagnosis of primary ovarian pregnancy are presented with a brief review of literatures.

      • Colchicine이 細菌增殖에 미치는 影響

        崔大卿,張明雄,朴鼎圭 충남대학교 의과대학 지역사회의학연구소 1981 충남의대잡지 Vol.8 No.2

        Attentions have been devoted to the effects of colchicine on the growth and biochemical characteristics of Bacillus subtilis (ATCC 6633) and Staphylococcus aureus (phage type 29) in BHI broth containing 1 and 5 mg per ml of colchicine. The results were summarized as follows: 1. Growth of Bacillus subtillis was decreased after 12 hours exposure to the 1 mg per ml of colchicine but growth of Staphylococcus aureus was not influenced to it. 2. Growth of Bacillus subtilis was remarkably decreased after 8 hours exposure to the 5mg per ml of colchicine but Staphylococcus aureus also remarkably decreased after 2 hours exposure to it. 3. One and 5mg per ml of colchicine was not influenced to the biochemical characteristics of Bacillus subtillis and Staphylococcus aureus. As above the result, it was suggested that 1 and 5mg per ml of colchicine was inhibited to growth of some bacteria but its effects was different to the bacterial species or strains. It was not influenced to the biochemical characteristics of some kind of bacteria.

      • 건강인에서 결핵균 30-kDa항원이 말초혈액 임파구증식에 미치는 영향

        최대경,고석신,김화중,조은경,백태현,신철식 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

        T lymphocytes are thought to play a central role in cell mediated immune response. To Study the T lymphocyte proliferative response to 30-kDa antigen purified from Mycobacterium tuberculosis H37Rv, peripheral blood lymphocytes isolated from healthy subjects were stimulated with the 30kDa antigen, crude antigen or PHA. Healthy subjects were divided into three groups so that PPD(+), PPD(±) and PPD(-). The proliferations of lymphocytes were measured by the incroporation of ^3H-thyrnidine. The results were summarized as follows: 1. For the PPD(+) person, at concentration of < 1 ㎍/ml, the proliferative response to 30-kDa antigen resulted in a mild reduction but crude antigen showed relatively rapid reduction. For the PPD(-) person, decreasing the concentration of the both antigens showed rapid reduction of proliferation 2. The lymphocytes proliferations to 30-kDa antigen and crude antigen were significantly increased in PPD(+) group when compared to those in PPD(-) group, but PHA response was no significant difference. 3. The sensitivity and specificity of lymphocyte proliferation assay to 30-kDa antigen and crude antigen when compared with skin test results were 92.3%, 100% and 76.9%, 50%, respectively.

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