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      • KCI등재

        국어 띄어쓰기 規定의 改善案 연구

        박정규(朴錠奎) 한국어문교육연구회 2006 어문연구(語文硏究) Vol.34 No.4

        A Study of Improvement in Korean Spacing Words Regulations Park, Jeong-gyu The purpose of this paper is to investigate the problems of Korean Spacing Words Regulations and to present an alternative plan. The problems of Korean Spacing Words regulations are as follows: 1. Current Korean Spacing Words Regulations is constituted 10 items but it is duplicated the dominant principle or same contents. As a result, current Spacing Words Regulations is uneconomical system. 2. Nevertheless, current Korean Spacing Words Regulations don't offer sufficient explanation because of unfaithful contents. 3. Also current Korean Spacing Words Regulations is overlapping various standards in addition to fundamental standard ‘word'. 4. Finally current Korean Spacing Words Regulations is contained self-contradictory explanation in 47, 48 items. Therefore this problems must be reflected in current Korean Spacing Words Regulations and must be improved in order to change more easy Spacing Words Regulations 이 연구는 국어의 띄어쓰기 規定에 나타난 문제점을 지적하고 이에 대한 代案을 제시하는 데 목적이 있다. 現行 맞춤법의 띄어쓰기 규정은, 우선 10개 條項 가운데 大部分의 항목이 띄어쓰기의 大原則을 확인하는 정도에 불과한 항목이어서 전체적으로 非經濟的 규정이라는 문제를 지적할 수 있는 이외에도 세부 조항이 10개 항이나 제시되어 있음에도 불구하고 각각의 조항에 나타난 설명이 상당히 未備하여 그다지 도움이 되지 못할 뿐만 아니라, 띄어쓰기 基準 또한 단어라는 기준 이외에 音節 및 專門 用語라는 異質的인 기준도 적용되어 문제를 더하고 있으며, 47항과 48항에서는 다른 조항들과는 완전히 相反된 설명 방식을 제시하고 있어 혼란을 야기하고 있다. 그러므로 이러한 문제는 현행 띄어쓰기 규정에 반드시 反映되어 국어의 띄어쓰기 규정이 보다 쉬운 띄어쓰기 규정이 될 수 있도록 수정되어야 할 것이다.

      • SCOPUSKCI등재

        TPA로 분화된 U937 세포에서 사람 세포거대바이러스에 의한 c-jun Promoter 활성도의 변화

        박정규,김대중,김진희,한태희,황응수,최명식,국윤호,최성배,차창룡,Park,,Chung-Gyu,Kim,,Dae-Joong,Kim,,Jin-Hee,Han,,Tae-Hee,Hwan,,Eung-Soo,Choi,,Myong-Sik,Kook,,Yoon-Hoh,Choi,,Sung-Bae,Cha,,Chang-Yong 대한미생물학회 1999 Journal of Bacteriology and Virology Vol.28 No.1

        Transient transfection assay has been done to evaluate whether the c-jun activation would be prerequisite to the induction of permissiveness against human cytomegalovirus using in vitro cell model in which U937 has been induced to express CD11b and CD14 to become potential monocyte/macrophage cells by TPA treatment. U937 cells were treated with $10\;{\mu}M$, $50\;{\mu}M$ or $100\;{\mu}M$ of TPA. The cell morphology change was observed and the expression of the CD11b and CD14 was confirmed by FACS. Differentiated cells were transfected with pJLuc reporter vector which contained the wild type murine c-jun promoter spanning the SP1, CTF, ATF/CREB and MEF-2 binding sites upstream of the firefly luciferase gene. After 48 hrs of transfection, the cells were infected with HCMV Towne strain and the luciferase activity was assessed at 1 hand 4 h pi. The transfection assay showed no activation of the c-jun promoter at 1 h pi, instead, it showed 2 times increase of the its activity at 4 h pi. There was no difference of the c-jun promoter activation between TPA treated and untreated U937 cells, implying that c-jun activation might not be prerequisite for allowing cells to be premissive to HCMV, although HCMV infection itself could activate c-jun promoter.

      • Interleukin-2와 결핵균 30 kDa 항원이 구개편도 및 말초혈액 T 세포 증식에 미치는 상승효과

        박정규,박찬권,조은경,김화중,백태현,고필준,김병국,남부현,나기상,박찬일 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1

        Widespread use of BCG has not controlled tuberculosis, and more effective vaccines are clearly needed. Although chemotherapy will remain the mainstay of antituberculosis treatment, the use of adjunctive immunotherapeutic modalitites is attractive, particularly in persons with drug-resistant tuberculosis. Administration of IL-2 or IFN-γto tuberculosis patients enhance bacillary elimination. Cell-mediated immunity is the critical protective immune response in tuberculosis. Mycobacterial antigens are recognized by T cells and that elicit production of protective cytokines are potentially important vaccine antigens. The 30 kDa antigen is secreted in large quantities by growing mycobacteria. That antigen elicits greater proliferation in lymphocytes from healthy tuberculin reactors than healthy tuberculin nonreactors. In this study, the T lymphocyte proliferative responses to 30 kDa antigen from Mycobactrium tuberculosis H37Rv were examined by using tonsilar and peripheral blood lymphocytes from PPD(+) and PPD(-) tonsilectomized persons. When cultured with 30 kD antigen, tonsilar mononuclear leukocytes and T cells of PPD(+) demonstrated more ^3H-thymidine incorporation than PPD(-) persons (stimulation index was 2.5 and 1.9, 0.8 and 1.0, repectively). Peripheral blood mononuclear cells (PBMC) and peripheral blood T lymphocytes were shown the similar responses to this antigen. The combination of IL-2 and 30 kDa antigen elicited a significant proliferative responsiveness in tonsilar mononuclear leukocytes and T cells of PPD(+) persons (SI was 20 and 14.1). PBMC and peripheral blood T cells of PPD(+) persons were also shown a significant responsiveness, but PPD(-) persons did not show. These results demonstrate that the 30 kDa antigen and IL-2 have a synergistic stimulatory property in mycobacteria sensitizing lymphocytes.

      • 결핵균 30 kDa항원과 Interleukin-2 혹은 Anti-CD28의 병합이 건강인 말초혈액 림프구와 단핵구 증식에 미치는 영향

        박정규,윤상호,조은경,김화중,백태현 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

        Cell-mediated immunity is necessary for protection against Mycobacterium tuberculosis. T lymphocytes are thought to play a central role in cell-mediated immune response. And in vitro stimulation of leukocytes with mycobactria or their products induces synthesis and release of several cytokines, including IL-2. To study the T lymphocyte proliferative response to purified 30 kDa antigen from Mycobacterium tuberculosis H37Rv, IL-2 or their combination, peripheral blood lymphocytes and mononuclear cells isolated from healthy subjects were stimulated with the 30 kDa antigen, IL-2 or both. The proliferations of lymphocytes and molnonuclear cells to 30 kDa or 30/32 kDa antigen were significantly increased in PPD(+) group when compared to those in PPD(-) group. It is confirmed here that have shown synergy between 30 kDa antigen and IL-2(250U) in the induction of lymphocytes and mononuclear cells proliferation in PPD(+) group. The proliferative response reflects synergy between two separate activation stimuli. And macrophage-like cells existed in peripheral blood mononuclear cells were shown to help the synergy of the proliferative response to mycobacterial antigen and IL-2. The proliferative responses of lymphocytes and mononuclear cells to 30 kDa antigen were more increased than those to 30/32 kDa antigen. So it was suggested that 30 kDa antigen was the more immunogenic antigen than 30/32 kDa antigen.

      • KCI등재

        17세기 후반 종교개혁사 논쟁과 길버트 버넷(Gilbert Burnet)의 역사서술

        박정규 영국사학회 2019 영국연구 Vol.0 No.41

        This paper analyses Gilbert Burnet's History of the Reformation of the Church of England. His three-volume work of the English Reformation was published over three decades to repudiate De Origine ac Progressu Schismatis Anglicani, written by Nicholas Sander in 1585. The second half of the seventeenth century when the first part of Burnet's book was published showed anti-popery mentality provoked by a series of political events. The central issue rested upon the historical justification of the Henrician Reformation. This dispute between Catholics and conformists reflects how they respectively understood the historical process of the establishment of the English Church for their sakes. Burnet's work was full of detailed accounts of religious and political circumstances which led to the establishment of the Church of England. However, there was also a strong sense of providential achievement which could be made by civil magistrates to fulfil what divine revelation desired. His work was not just the historical writing of the Reformation but was an account of royal propaganda that reflected the religious situation in which the Church of England struggled for supremacy over other religious persuasions in the late seventeenth century. 본 논문은 길버트 버넷의 『잉글랜드 국교회 종교개혁사』의 역사서술을 분석한다. 버넷은 1679년 가톨릭 역사가 니콜라스 샌더의 『잉글랜드 분파의 기원과 성장』을 겨냥하여 30여 년간 총 3권에 걸쳐서 16세기 잉글랜드 종교개혁사를 집필했다. 버넷의 역사서술은 17세기 후반 일련의 정치적 사건으로 인해 촉발된 반가톨릭 정서가 고조된 상황에서 써졌다. 이 시기 국교회와 가톨릭교회가 벌인 논쟁의 핵심은 바로 16세기 잉글랜드 종교개혁의 역사적 정당성에 대한 문제였다. 이 두 진영 간의 종교개혁 논쟁은 잉글랜드 프로테스탄트 교회가 세워진 과정을 역사적으로 어떻게 바라보는가에 대한 역사적 논쟁이기도 했다. 버넷의 『종교개혁사』는 잉글랜드 국교회의 탄생을 둘러싼 종교적·정치적 배경의 풍부한 설명으로 가득 차 있지만, 그 이면에는 잉글랜드 세속권력자의 신성한 권위가 어떻게 현세에서 신의 계시를 구현하는 데 이바지 하였는가를 보여주는 정치선전물의 성격도 띄고 있었다. 그의 저술은 단순한 역사서가 아니라, 17세기 후반 잉글랜드 국교도가 프로테스탄트교회의 종교적 우위를 확보하고자 하는 종교적 의도가 담긴 시대적 산물이었다.

      • KCI등재

        Infection of Thyroid Cyst Occurring 1 Month after Fine-Needle Aspiration in an Immunocompetent Patient

        박정규,전언주 대한갑상선학회 2018 International Journal of Thyroidology Vol.11 No.2

        Fine-needle aspiration (FNA) with ultrasonography is considered a minimally invasive and safe procedure. Complications of it are infrequent and occur immediately or within a few days after FNA. Such complications may occur mainly in patients with underlying problems. We here report a rare case of thyroid cystic nodule infection occurring 1 month after FNA in an immunocompetent patient and serial sonographic findings in this patient. A 33-year-old woman with a cystic nodule including partially isoechoic solid areas on the right thyroid gland complained of difficulty swallowing and painful sensations in the right neck 1 month after FNA. On follow-up examination, the cystic nodule and perithyroidal soft tissue were suspicious of infection. The possibility of infection after FNA should be considered even if the patient is immunocompetent in order to prompt evaluation and immediate management with empirical antibiotic therapy to avoid life-threatening complications.

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