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서태수,박윤기,김한수,이용덕 대구보건대학 1992 대구보건대학 論文集 Vol.13 No.-
In addition to the physical pains, the rheumatoid arthritis patients accompanies the joints to deformities of the hand and feet, the psychological disturbance followed by the continuous fight against disease. It is effective that the acute stage of RA comes under rest, splint, joint exercise, the subacute stage of RA is applicable to heat therapy, and the chroinc stalge of RA applies range of motion exercise, muscular strengtlhening exercise, occupational therapy, activities of daily living therapy, ortlhotic therapy. As the treatment will be changed during the process of disease, the active treatment program will contmuous observation is needed, and it will be also important for therapist to induce the helpers knowing about this disease and help the patient well in treatment the disease.
아스파라거스 부산물 추출물의 숙취 해소 및 통풍완화 효과
서태수,이재훈,임승태,이득찬,한준희,홍민,최다혜,이선엽,이재학,유근형 한국약용작물학회 2022 한국약용작물학회지 Vol.30 No.2
Background: Given the reported pharmacological effects of rutin from asparagus stems and roots, here, we assessed the anti-hangover and anti-gout effects of asparagus stem and root extracts. Methods and Results: We found that rutin amount in ethanol extracts of asparagus stems was 10.15 ㎎/g, and in hydrothermal extracts of asparagus roots it was 3.28 ㎎/g. Alcohol dehydrogenase and aldehyde dehydrogenase activities in asparagus-stem extracts were 80% and 40% of those in the control group, respectively. Following hangover induction in rats using alcohol, an injection of 400 ㎎/㎏ body weight (BW) of the extract significantly reduced the blood alcohol concentration compared to that of the control group. Additionally, blood gamma-glutamyl transpeptidase (GGT), glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) concentrations measured 5 h after alcohol administration revealed that treatment with 400 ㎎/㎏ BW of extract significantly reduced GGT and GOT concentrations compared to the control group, whereas changes in GPT were not significant. Moreover, xanthine oxidase activity after treatment with hydrothermal extracts of asparagus roots was 44.01 ± 0.32%, showing 53.3% inhibition compared to the positive control (allopurinol; 82.50 ± 4.98%). To assess the anti-gout effect of hydrothermal extracts of asparagus roots, we induced gout in rats by intraperitoneal injection of potassium oxonate and measured blood uric acid, creatinine, and blood urea nitrogen concentrations at 3 h post-administration of the extract. The results showed a significant reduction in creatinine and uric acid levels in the treated group compared to the control. Conclusions: These findings demonstrated the potential of asparagus stem and root extracts as functional ingredients.