한강시민공원 체육시설 현황과 효율적 활용 방안에 대한 연구

한진욱,김진호 경희대학교 체육과학연구소 1999 體育學論文集 Vol.27 No.-

The aim of this study is primarily to examine the current state of the sports facilities for the Han-Gang Citizens' Park and to propose its effective utilization plans for the coming 21st century. The main findings and conclusions can be described as follows: 1.Strengthening of publicity fucntions 2.To provide citizens with various means of easy access to the Park such as shuttle buses and samaul buses 3.Developments of new programs for the disabled and senior citizens 4.Extensive utlization measures for the evening hours 5.To make the Park distictive according to each distict 6.Reorganization of the Parks' administrative structures 7.Diversification of programs, and training and retaining instructors of an excellent caliber.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

첫 입원치료 받은 정신분열병 환자들의 삶의 질 추적 연구

한오수,이철,최지욱,홍진표,김창윤 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.6

울산의대 서울중앙병원 정신과에서 첫 입원 치료를 받고 퇴원하여 2년 혹은 5년이 경과한 정신분열병과 기타 정신병 108명 중 최종 73명(응답을 66%)을 대상으로 Heinrichs등이 고안한 삶의 질 척도(Quality of Life Scale)를 사용하여 현재의 삶의 질을 평가하여 다음과 같은 결과를 얻었다. 첫째, 삶의 질 측면 4가지 측면인 대인관계, 직업적 역할, 정신내적 요소, 및 일상적인 물건 및 행동 모두에서 삶의 질이 전반적으로 저하되어 있음을 관찰할 수 있었다. 대인 관계 영역 중 가족 구성원과의 인적 관계 항목은 다른 항목에 비해 상대적으로 만족도가 높았다. 둘째, 정신분열병군의 삶의 질은 기타 정신병군에 비해 대부분의 삶의 질 항목에서 유의하게 낮은 것으로 나타났다. 셋째, 2년 경과군과 5년 경과군 사이 삶의 질은 유의한 차이를 보이지 않았다. 발병 초기 삶의 질 저하가 상당기간 유지됨을 시사하였다. 넷째. 퇴원 후 삶의 질에 영향을 미치는 변인으로는 첫 입원 치료 기간이 유의한 역상관관계를 보였으며 또한 다변량 회귀 분석에 있어서도 같은 결과를 보였다. 이는 초기 치료에 대한 반응 정도가 부분적으로는 향후 삶의 질을 예측할 수 있음을 시사한다. 기타 첫 입원 당시의 연령, 교육 수준. 사회경제적 수준, 첫 입원하기까지의 이환 기간, 첫 입원 당시 Global Assessment of Functioning 입원 치료시 약물용량 등은 삶의 질과 유의한 상관관계를 보이지 않았다. Objectives : One object of this study is to provide a descriptive level of qua1ity of life(QOL) in a group of the first admired schizophrenic patients through interviews being performed after two or five yeah of fo11ow-up, and comparing them with patients in psychotic disorders other than schizophrenia. Another object is to identify clinical variables on the first admission which correlate to QOL factors, after two or five years of fo11ow up. Methods : A total of 73 subjects of the first admitted patients with schizophrenia(n=57) and psychotic disorders other than schizophrenia(other psychotic disorders group, n= 16) were selected. A Quality of Life Scale(QLS) measuring 21 items of life variables was used. Demographic and psychiatric data were obtained through medical records and psychiatric interviews. Results : Schizophrenia group(n=57) showed moderate decrease(mean 3.7 of 6) in all aspect of quality of life. However, the schizophrenia group displayed a relatively high score in relations with household members(mean=5.2) only among 21 QOL items. Comparison to other psychotic disorders group(n= 16), schizophrenia group showed a significant decrease in almost all aspects of QOL. No significant difference was obtained between the 2 year(n=27) and the 5year(n= 30) group. Duration of the first admission showed a significant correlation with current quality of life in the schizophrenic group. Conclusions : The significantly decreased score of quality of life suggests the need for careful observation and therapeutic concern for the early stage of schizophrenia. The schizophrenic group's relatively high score in relations with household members in this period may provide the importance of rehabilitation to improve their quality of life. Duration of the first admission may be a useful predictor of their subsequent quality of life.

위 전절제술을 받았던 환자에서 아급성 연합성 변성 1예

한정호,하현욱,이정석,송은향,김우정,김두응,최진영 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Subacute combined degeneration is a metabolic disorder of the spinal cord caused by vitamin B12 deficiency. A 72-year old man was admitted with weakness and tingling sensation of the bosh upper extremities. 9 years ago, he was diagnosed as having stomach cancer. So total gastrectomy with splenectomy was done at that time. The complete blood cell counts and morphology revealed megaloblastic anemia. Nerve conduction velocity study(NCV), electoromyography(EMG) and somatosensory evoked potentials(SEP) showed diffuse sensorimotor peripheral neuropathy. Magnetic resonance imaging(MRI) showed an increased T2-weighted signal, mild decreased T1-weighted signal, and slight contrast enhancement of the posterior columns of the cord in the cervical and upper thoracic spinal region. He was treated with vitamin B12 supplements and improved gradually. If abnormal sensation and muscle weakness was developed after gastrointestinal surgery, subacute combined degeneration should be considered in the differential diagnosis. We describe MRI findings of a typical case of subacute combined degeneration, which was induced by total gastrectomy.

한국 재래산양에서 Bovine Viral Diarrhea, Bovine Herpesvirus-1, Parainfluenza Type-3 바이러스에 대한 혈청학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

The 948 goat sera were serologically tested for ten pathogens including bovine viral diarrhea (BVD), bovine herpes virus type-1 (BHV-1) and parainfluenza virus type-3 (PI-3). By viral neutralizaion test, three pathogens including BVD virus, BHV-1, PI-3 were applied for screening each neutralizing antibody and its titration. Among 948 sera, there were 215 seropositives (22.7%) against BVD virus, 25 (2.6%) against BHV-1 virus, and 161 (17.0%) against PI-3 virus, respectively. In the seropositive cases to BVD virus, provincial prevalence of them were recorded as Gyeongnam(30.8%) for the highest one, while as Jeonbuk (15.8%) and Gyeongbuk(l6.7%) relatively for the lower ones. Among them, higher than 1:8 in antibody titration was classified as 74 cases (34.4%) which were suspected the cycle of its infection in their herds. Among the seropositives to BHV-1, it was relatively lower prevalence rate ranging from 1.7% to 6.7% that those of BVD virus and PI-3, but more importantly they were prevailing across the country. Most of the seropositive cases (42.9%) to PI-3 were classified as 1:4-1:16 in titration, but also distributed all around the country. The prevalence in goats varied according to areas (15.8 to 30.8%). Related to the provincial prevalence of three viral agents in Korean goats, it seemed that three viral pathogens would be directly or indirectly involving in various disorders as primary or secondary causative agents resulting in decreased productivity.

고속 주행 모드에서 자동차 디퓨저의 스트레이크 개수와 배치에 따른 공기저항 유동해석

이진호,박성하,최동석,한영진,곽나영,이상욱 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

This study proposes an optimized diffuser strake design that can improve driving performance for cars in high-speed driving mode. The speed of the vehicle is set to 160km/h, and the number of strake is set to 4, 6 and 8, and the angle of the diffuser is set to 4, 5 and 6 degrees. The arrangement of the strake is centered, edged and equally arranged. The optimized diffuser design induced with the Ansys Fluent analysis shows a drag coefficient of 16% less than the basic diffuser-free model at a diffuser angle of 6 degree, 8 strakes, and equal arrangement.

한국 재래 산양에서 Leptospira spp.에 대한 혈청역학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

Between January 1999 and September 2001, 948 sera (120 from each province except 108 from Chungbuk) from 8 provinces were sampled from Korean goats. All the samples were serologically tested for Leptospira spp. By the microscopic agglutination test against four L. interrogans serovars including canicola, icterohaemorrhagiae, pomona and hardjo, 948 Korean goats were confirmed as 11 seropositives (1.2%) only infected with L. icterohemorrhagiae. All positive sera were collected from Gyeonggi (5), Gangwon (4) and Chungbuk (2). Titration of them were classified as 1:100 of 10 sera except one case with 1:200 from Gyeonggi. It was meaningful that the pathogen in Korean goats was mainly distributed in the northen part of the country. Consequently, the results in the study were confirmed and analyzed the recent status of infection of leptospirosisas zoonotic agentsome in Korean goats.

교육대학원에 있어서 초등 과학교육 영역의 중요성과 그 운영방안

오진태,옥치율,한영욱,이형철,김용권,임채성 釜山敎育大學校 1994 부산교육대학 논문집 Vol.30 No.1

The future society is expected to be rapidly change in all areas, that is, the length of change time is becoming much smaller than that of generation time. It is very important to prepare the citizens who possess scientific literacy which actively cope with the rapid changes and specialization of society. The sources of rapid changes may be due to the developments in science and technology. Therefore, the importance of science education will be increasingly high. Scientific literacy should be improved basically and systematically from the early stages of formal education. Teachers who are responsible to educate children should be able to research in the areas of science education as well as science itself, and to have capacity to transmit them to the classroom. To do this, the graduate course and the science education within the system beyond the level of college education are essential parts of teacher education. In the graduate course, it is important that science itself and pedagogy of science should be balanced.

2007년 대한감염학회 권장 성인 예방접종 권장안

강진한,김홍빈,손장욱,이상오,정문현,정희진,최영화,최정현,최준용,최희정 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

In 2007, the Korean Society of Infectious Diseases recommended an immunization schedule for adults residing in Korea. This recommendation includes four categories: standard immunization for healthy persons, supplementary immunization for persons with underlying illnesses, recommendations for health-care personnel and for international travelers. The Standard Immunization Schedule consists of universal vaccination (tetanus-diphtheria/tetanus-diphtheria-pertussis (Td/Tdap); hepatitis A vaccine for persons aged 20s; human papilloma virus vaccine for women under 26 years old; meningococcal vaccine for military recruits and college students in dormitories; influenza vaccination for persons aged 50 years or more and pregnant women; and pneumococcal vaccination for persons aged 65 years or more) and catch-up vaccination (hepatitis A vaccine for persons aged 30s; hepatitis B vaccine, varicella and MMR vaccines for persons who have uncertain specific immunities). The Supplementary Immunization Schedule recommends 4 vaccines, i.e., pneumococcal, influenza, meningococcal, and Haemophilus influenzae type b, appropriate to the underlying illnesses, and confirmation of the presence of antibodies to hepatitis A and hepatitis B. The Recommendation for Health-Care Personnel includes universal vaccination (influenza and pertussis) and catch-up vaccination (hepatitis B, measles-mumps-rubella and varicella for seronegative health-care personnel). The Recommended Immunization for International Travelers focuses reinforcement of vaccinations for healthy persons and includes certain immunizations necessary for international travel (yellow fever, meningococcal, plaque, tick-borne encephalitis, and cholera). These guidelines can be seen at www.ksid.or.kr.

한국인 집단에서 미토콘드리아 DNA의 'Asian-specific 9-bp결실'다형현상

김욱,진한준 단국대학교 1999 論文集 Vol.34 No.-

Length changes in mitochondrial DNA (mtDNA) offer a useful marker for the study of female aspects of human population history. One such length change is the intergenic COⅡ/tRNA^Lys 9-bp deletion, which the region usually contains two tandemly arranged copies of a 9-bp sequence (ccccctcta) in human mtDNA. This deletion has been reported at varying frequencies in populations from Asia. Polynesia, the New World, and sub-Saharan Africa. This genetic polymorphism of mtDNA was analyzed in samples from 171 unrelated individuals from the Korean population and compared the frequency and distribution of 9-bp deletion with other Asian population. The frequency of the 9-bp deletion was found to be 17.5% (30/171) in the Korean populations. Uncommonly, a new insertion allele of approximately 6-bp in the intergenic COⅡ/tRNA^Lys region in the Korean population (2/171) was first identified in this study. East Asian populations including Chinese. Japanese, and Koreans were relatively homogeneous in the frequency of 9-bp deletion. with the exception of the low frequency of this deletion in Mongolians. On the other hand, Indonesians and Malaysians of Southeast Asian populations were found to show relatively high frequencies of the 9-bp deletion. Based on results of the frequencies of the 9-bp deletion, the Japanese population appeared to have a closer genetic relationship to Koreans than to the other surveyed Asian populations. Therefore, the results of this study also supported the hypothesis that a large amount of the gene pool in mainland Japanese was derived from the continental gene flow after the Yayoi Age.