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정창화,심유섭,김성준,박철휘 대한상하수도학회 2003 상하수도학회지 Vol.17 No.6
The purpose of this study was to develop a solution to reduce the cost of methanol as external carbon source. The raw water of J-S.T.P. contains low concentration of readily biodegradable organics and high concentration of nitrogen due to the influents of industrial wastewater and leachate. Consequently, the influent C/N ratio is very low, and thus the supplemental addition of methanol is required to provide external carbon source for denitrification. Pilot plant experiments composed 2-stage denitrification process were performed to examine the effects and performances of the selected carbon source and the operation conditions for applications in practice. When the same amount of denitrifying substrates based on denitrification rate of methanol were injected, the effluent T-N concentration of using mecellulose wastewater was similar to that of methanol. Comparing the influent concentration of carbon source and the denitrification rate, it was shown that the denitrifying potential of mecellulose wastewater was 60% and injecting 1/3 of carbon source into the preanoxic tank was appropriate to ensure the stabilized effluent water quality. The COD,, requirement of mecellulose wastewater per nitrogen removed was 1.4 times of the required amount for methanol, and the settlability of sludge treated with mecellulose wastewater improved about 29%, which confirmed its potential as effective external carbon source.
GPS-X 시뮬레이션을 이용한 2단탈질 공정에서 외부탄소원 적용성 평가
정창화,심유섭,김태형,박철휘 대한상하수도학회 2004 상하수도학회지 Vol.18 No.1
The purpose of this study was to evaluate adaptability of external carbon source using GPS-X program in pilot plant composed with 2-stage denitrification process. The result from analysis of pilot plant operation and GPS-X simulation showed that effluent concentration could be simulated similarly by modifying operation conditions, such as DO concentration, C/N ratio and other calibrated parameter. In order to satisfy the standard of the effluent water quality on T-N of 20㎎/L, it required approximately 3.1 of C/N ratio and 50% of nitrogen removal efficiency when influent T-N is 36.9㎎/L. To maintain the stable water quality of the receiving water, the effluent T-N concentration should be less than 10-15㎎/L and the appropriate C/N ratio to remove nitrogen was 4.27-6.82. The analysis of sensitivity to kinetic coefficient and reaction constant showed that Y_(H) and μ_(mAUT) were most sensitive to nitrate and ammonia nitrogen, relatively and sensitivity coefficient of their were 1.32, 1.98. It was concluded that as Y_(H) decreased and μ_(mAUT) increased, the reaction rates of denitrification and nitrification increased and the removal efficiencies of NO₃^(-)-N and NH₄^(+)-N improved.
송근호,유진호,김정은,장화익,이광래 江原大學校 産業技術硏究所 2005 産業技術硏究 Vol.25 No.A
Auto exhausts and air pollution can become trapped in the cabin of vehicle, reducing the amount of oxygen available for breathing. Driver may feel sleepy, headaches, nausea, confusion, dizziness and lower levels of oxygen can damage the driver's general health. Consequently, oxygen generator purified oxygen into the car to help driver get the oxygen driver's body needs. In this study, in order to evaluate the oxygen generator performance, the samples that the various conditions(humidity(50%, 100%), flow and oxygen concentration) were examined. There were three types of oxygen generator; sample 1(2.5ℓ/min, 36%0₂), sample 2(4.5ℓ/min, 41%0₂) and sample 3(5ℓ/min, 39%0₂). As the humidity increased from 50% to 100%, the oxygen concentration of the sample 1(36%), 2(41%) and 3(39%) was reduced 31%0₂, 38%0₂ and 38%0₂, respectively. Also, the each sample measured that effect of human in car on oxygen concentration, if the oxygen concentration is one person in car, each sample of oxygen concentration was 20.8%0₂, 23.7%0₂ and 21.2%0₂. From the above results, it was shown that oxygen generator for car, if the oxygen concentration is increased, effect of humidity is reduced, and that in the sample of supplying a high-rate of oxygen, the oxygen concentration is increased. It was suggested that effect of humidity on oxygen generator for car can be reduced according to the supply of oxygen.
백창렬,이동건,최정현,정현화,조유경,박훈준,이승훈,박윤희,이교영,민우성,김춘추,신완식 대한감염학회 2001 감염 Vol.33 No.4
As a result of the enlarging pool of unvaccinated children and young adults, there has been an increase in measles in our countries. In these situation, it has been reported that measles associated pneumoinia is easily complicated with fatal respiratory failure, espycially in immunocompromised patients. Herein we report the case of lethal measles pneumonia after allogenic hematopoietic stem cell transplantation in adults proven by autopsy. Recently, one case of measles was encountered in 39-year-old female patients after allogenic bone marrow transplanted case (chronic myelogenous leukemia), who progressed into interstitial pneumonia pattern, despite treatment including antibiotics, immunoglobulin. The patient died of giant cell pneumonia compatible with that of measles which was comfirmed in the section of necropsy lung specimen. (Korean J Infect Dis 33:301∼309, 2001)
Analysis of Glycated Serum Proteins in Type 2 Diabetes Patients with Nephropathy
Kim, Mi-Ryung,Yu, Shin-Ae,Kim, Mi-Yeon,Choi, Kyung Mook,Kim, Chan-Wha 한국생물공학회 2014 Biotechnology and Bioprocess Engineering Vol.19 No.1
The aim of this study was to screen for proteins that are susceptible to glycation under hyperglycemic conditions in patients with type 2 diabetic nephropathy. Serum proteins were analyzed by a proteomic approach using two-dimensional electrophoresis (2-DE) and ESI-Q-TOF MS/MS. Gels were stained with Pro-Q Emerald 488 to analyze the serum glycoproteome, followed by silver nitrate to examine the total serum proteome. Patient sera were divided into four groups according to their microalbuminuria index: type 2 diabetics with normoalbuminuria, microalbuminuria, and overt nephropathy, and healthy subjects. When the HbA1c levels of the diabetic groups were examined, groups with higher HbA1c exhibited higher fructosamine levels, suggesting that the loss of glycemic control affected the glycation of serum proteins. The proteins that became glycated under poor glycemic control were PEDF, apolipoprotein J precursor, hemopexin, immunoglobulin mu heavy chain, and immunoglobulin kappa chain. As albuminuria increased, a marker of kidney damage, the levels of glycated prekallikrein and complement factor C4B3 also increased. The glycated proteins identified in this study may provide the foundation for the development of novel markers of diabetes, hyperglycemia, and diabetic complications.
김영재,김희종,김은화,송은섭,김문중,김귀완,한기옥,류영근,유제윤 대한내과학회 1991 대한내과학회지 Vol.41 No.5
Rifampicin is a widely used drug for the treatment of mycobacterium tuberculosis infections. This drug, among others, is a potent inducer of the hepatic mixed oxygenase enzymes involved in drug metabolism. Therefore, the effects of drugs or hormones metabolized by liver enzymes may be influenced by rifampicin administration. Thus, concurrent treatment of rifampicin and the glucocorticoid hormone can lead to decreased bioavailability of the glucocorticoid hormone and to icreased requirement. With a brief review of the literature, we report a case of rifampicin-induced adrenal crisis, in which the patient received a physiologic maintenance dose of prednisolone and rifampicin.