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      • 젊은 남자 성인의 칼슘과 철의 영양상태에 관한 연구

        박영숙,곽주영,권지혜,류화라 순천향대학교 기초과학연구소 2002 순천향자연과학연구 논문집 Vol.8 No.1

        A survey was performed to 174 male young men who were living alone(40 persons) and shared living with friends(4143 persons) in Chungnam province. Their average age was 22.6 years old, height 171.8 ㎝, and weight 65.6 ㎏. Their daily calcium intake level was averaged 271.9±169.1 ㎎, which was 38.8 %RDA. Comparing calcium intake of each mealtime, breakfast, lunch, dinner, and snacks were composed of 18.6%, 30.0%, 34.0% and 17.4%, respectively. Their daily iron intake level was averaged 8.9±10.8 ㎎, which was 74.3 %RDA. Comparing iron intake of each mealtime, breakfast, lunch, dinner, and snacks were composed of 15.4%, 33.6%, 36.3% and 14.7%, respectively. These results suggested that deficiency of the two minerals in young male adults were severe and the nutrient qualities were also poor, no matter of their living alone or with accompanies. The deficiency was more profound in calcium than iron. And we observed iron nutriture differed significantly according to their living status, such as iron intake and its %RDA were significantly worse in single living subjects than the others. However calcium did not show significant difference. We concluded that shared living environment in young male adults could possibly improve their dietary mineral intake levels.

      • Helicobacter pylori와 대장균의 Shuttle Vector 개발

        조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

        In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

      • 사철나무 알칼로이드, Euojaponine의 NMR스펙트럼의 분석

        柳載夏,李沼映,李叔淵,韓秉勳 숙명여자대학교 약학연구소 1994 약학논문집-숙명여자대학교 Vol.10 No.-

        The strutures of euojaponines, alkaloidal components from Euonymus japonica are composed of β-agarofuran type sesquiterpene and pyridic dibasic acid, and they are linked via cyclodiester bonds. The structures of these compounds were elucidated by the application of various two dimensional NMR methods. From the results of complete interpretation of NMR spectra, several correlating aspects between structure and spectral pattern of sesquiterpene moiety were found, which can be utilized for the structural determination of the same family compounds.

      • 生長調節物質의 處理가 고추의 着果 및 果實特性에 미치는 影響

        金永信,呂承淑,李禧珠,李政明 경희대학교 부설 식량자원개발연구소 1991 硏究論文集 Vol.12 No.-

        A series of experiments were conducted to investigate the effect of some growth regulator treatment on the fruit set and fruit growth in a male sterile inbred line of hot pepper(Capsicum annuum ) which normally bears bean-sized tiny fruits only. Major results can be summarized as follows. 1. In the first experiment, which was consisted of Tomtlane treatments alone or in combination with gibberellic acid, fruit growth was not significantly influenced by any of the treatments. Only the hand-pollinated flowers with viable pollens from other fertile plants gave rise to significantly larger fruits suggesting that competition for nutrients within a plant may reduce the effectiveness of the chemicals treated. 2. 2, 4-D treatment, dipping the flowers in l00ppm solution, was found to be the most effective in inducing parthenocarpic fruit enlargement as compared to other chemicals in the second experiment. 3. In the 3rd experiment, which included all the treatments tested in the first and second experiments, 2,4-D treatment was found to be the most effective followed closely by Tomatotone (p-CPA) treatment. 4. Addition of gibberellic acid to Tomatotone appeared to increase the effectiviness of Tomatotone treatment. Addition of gibberellic acid to NAA or Tomatlane failed to show any significant additive effect. 5. Highly significant postitive correlation was found between the fruit fresh weight and the fresh weight of the placentae tissue thus suggesting the important role of placentae tissue in enlargement of fertilized fruits.

      • 수술실 오염도감소를 위한 수술실공조시스템에 대한 연구

        김천숙,박은정,강규식,김지은,안기량,권진형,유시현,주영철,권순정 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

        Background: The OR(operating room) should provide an optimum environment that is safe for the patient and the working personnel. The air ventilation system of OR has been studied to decrease the contamination of air. We investigated the flow and contamination of the air in OR at our hospital. Method: Cultures in OR were made and the number of bacteria and fungi were calculated. A two-dimensional model for the cross-section of an operation room is developed for the CFD (computational fluid dynamics) analysis. The characteristics of air flow in the empty operation room and in the occupied operation room are calculated by using a CFD program. Results: The current air ventilation system of our hospital does not deliver the clean air to the operating site efficiently in occupied OR. Conclusions: We suggested a new location of air ventilation system which improves air venting with little increase of the cost of equipment.

      • 혈당측정기 GlucoDr™ System의 평가

        박철영,류미숙,우정택,김성운,김진우,김영설,안규정 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

        연구배경: 당뇨병 환자에서 엄격한 혈당조절은 환자의 예후와 밀접한 관련이 있다. 혈당조절을 철저히 하기 위해서는 자가 혈당 측정기의 사용이 필수적이라 할 수 있다. 또한 저혈당이 빈번하게 발생하거나, 위험요소가 있는 환자들에게도 유용하게 사용될 수 있다. 이에 저자들은 전기화학감지법의 원리를 이용하여 국내에서 처음 생산된 자가혈당측정기인 GlucoDr™ blood Glucose Testing System(ALL Medicus, Co, Korea)를 현재 국내에서 시판되고 있는 다른 제품과 비교, 평가하여 임상적 유용성을 살펴보고자 하였다 방법: 혈당측정기준장비는 YSI 2300 STAT Plus(YSI Incorporated, USA)를 사용하였으며 GlucoDr™외에 Glucocard(KDK, Japan), Precision QID(Abbott Laboratories, Co, USA), Glucotrend(Roche, USA), Surestep(Lifescan, USA)의 다른 혈당측정기를 같이 평가하였다. 정밀도, 직선성, 비교방법과의 상관관계 평가, 검체량에 따른 영향, 헤마토크리트에 따른 영향, 검사자에 따른 영향, 항응고제에 따른 영향들을 평가하였다. 결과: 본 연구에서의 주된 평가대상인 GlucoDr™의 평가결과, 정밀도를 나타내는 검사 내, 검사 간 변이계수는 8%이내였으며, 45~500mg/dL 범위에서 R²=0.9906, 0.9984 정도의 직선성을 나타내었다. 본 연구에 있어 비교방법으로 이용한 YSI 2300 STAT Plus와의 상관관계 및 정확도는 y = 1.0058x + 0.453, R = 0.9853인 것으로 나타났다. 검체량이나 검사자 및 항응고제에 따른 측정값에는 유의할만한 차이가 없는 것으로 나타났으나, 헤마토크리트가 증가 또는 감소함에 따라 최소 10%에서 최대 26% 가량의 영향을 받는 것으로 관찰되었다. 결론: GlucoDrTM는 국내 사용되는 다른 혈당측정기와 비교하여 유용할 것으로 생각된다. Background: Self-monitoing blood glucose devices are sidely used in monitoring and point-of-care testing for the management of diabetic patients. We performed the present study to evaluate the performance of the GlucoDr™ blood glucose testing system using an electrochemical technique. Method: The GlucoDr™ was evaluated for linearity, precision, comparison of method, the effect of sample volume, hematocrit concentration, reapplication, operator and application methods. Results: The GlucoDr™ showed good linearity for glucose concentrations ranging from 52mg/dl to 475mg/dl(r²=0.971). The single day, and day-to-day, CV were within 8%. Excellent correlation was found between the GlucoDr™ and YSI 2300 STAT Plus(y=1.0058x + 0.453, r²=0.9710). The sample volume, reapplication, operator and application method produced no significant effect on the test result. An overestimation in the glucose values was found with low hematocrit concentrations. There was no significant effect by the anticoagulants, with the exception of citrate. Conclusion: The GlucoDr™ showed good linearity, precision and correlation with the reference method and provided rapid and reliable result for blood glucose levels. Therefore, the GlucoDr™ seems appropriate for clinical use in the management of diabetic patients.

      • 폐농양 및 복부농양을 일으킨 Eikenella corrodens 감염 2예 : Two Case Reports and Review

        정용희,류미숙,김영식,이우인,이희주,서환조 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.1

        Eikenella corrodens is a slowly growing, facultative anaerobic gram-negative bacillus. It is a normal inhabitant of the human upper respiratory tract, and it is recognized as an infrequent cause of invasive disease. To date, a few cases of E. corrodens infection were noted from all other organ. We report herein two cases of E. corrodens infection. In one case E. corrodens was isolated in the lung abscess and in the other case it was in the appendiceal abscess. The patients were treated empirically with penicillin G. The results of the bacterial culture and sensitivity test were available with it. The patients were discharged 15 days later with marked improvement after treatment. Our report clearly demonstrates that E. corrodens can be the pathogen of lung abscess and intraabdominal abscess. We reviewed descriptions from the literature of infections caused by E. corrodens.

      • 고학력 여성인력 개발 및 활용을 위한 평생학습 지원체제 연구

        박승호,유숙영 서울여자대학교 여성연구소 2006 여성연구논총 Vol.21 No.-

        One of the most serious problems of our society is the very low rate of high educated or high skilled women's social participation rate, and limited opportunity in higher value-added businesses for women. Efforts to make human resources of high educated women are so urgent for entering top 10 countries with competitive human power that Korean government enacted laws promoting development and use of them. These steps can be proper only when based on understanding of their real situation and their needs. With study on relative documents and survey on high educated women, we made some suggestions for a lifelong learning support system promoting development and use of high educated woman resources. First, the system should be based on woman's needs driven from their places in their life cycles. Second, the system sould be various on the learning style and characteristics of women. Third, collaborative relations between lifelong learning system and the local community need to be built. Forth, woman lerners should be encouraged by emotional supports from other family members and shared household chores. To develop and use high educated woman resources, more educational facilities in the community should be used for women to learn at any time and in any place. Second, more active supports should be offered through close cooperation among lifelong educational institutes. Woman learners can manage their course of career development with the database on their learning. Third, by database on high educated women, they should be given more opportunities to get appropriated places for their abilities. Forth, higher value-added business for high educated women should be developed. Finally, more opportunities of grant-type lifelong education should be offered to them.

      • KCI등재

        Efficient Unlinkable Secret Handshakes for Anonymous Communications

        Eun-Kyung Ryu1,Kee-Young Yoo,Keum-Sook Ha 보안공학연구지원센터(JSE) 2010 보안공학연구논문지 Vol.7 No.6

        The technique of secret handshake is used as a fundamental building block for anonymous peer-to-peer communications over untrusted networks. However, the fact that most existing schemes fail to meet unlinkability causes the use of schemes to limit for practical use. In this paper, we provide new constructions for unlinkable secret handshake, allowing arbitrary two communication parties with the same role in either one single group or multiple groups to privately authenticate each other. Compared to previous works, our techniques have much better performance in terms of both computational and communication cost, while they obtain good security results.

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