12주간의 유산소성 운동이 비만 초등학생의 신체조성과 혈액성분에 미치는 영향

윤미수,최건식,고성경,정소봉 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

[Purpose] The purpose of this study was to investigate the effect of aerobic exercise training on the body composition and blood components in obese elementary children after 12 weeks. [Methods] Subjects of this study were composed of 20 male students ranging in age from 9 to 12 years who were classified into two groups, obese exercise group(n=10) and normal control group(n=10). For 12 weeks, obese exercise group performed the aerobic exercise training that the program was composed by Yoon. The blood samples were taken before and after 12 week Paired t-Test was adopted to analyse the difference between before and after aerobic exercise training. [Results] body fat of obese exercise group was decreased 4.8% after aerobic exercise training(p<.01) and that of normal control group was decreased 0.1% during same time(NS). Among the blood lipoprotein, total cholesterol(p<.01), LCL-C(p<.01), and triglycerides(p<.05) of obese exercise group were decreased after aerobic exercise training, but not changed HDL-C of same group. Red blood cell, Hemoglobin(p<.65) of obese exercise group were increased after aerobic exercise training. Glucose of obese exercise group were decreased after aerobic exercise training(p<.05), but not changed in Ca and P. [Conclusion] In conclusion, aerobic exercise training for 12 weeks seems to reduce body might and body fat, and to change the profiles of blood Component in obese elementary children.

새로운 의약품의 합성에 관한 연구(IV):새로운 세파로스포린 항생물질의 합성과 그의 생물활성에 관한 연구

최원식,최소영,윤경하 순천향대학교 1994 논문집 Vol.17 No.3

New cephalosporin antibiotics, 7-[(3, 4-dihydro-6-alkoxycarbonyl-2, 2-dimethyl-2H-l, 4-thiazin-3-yl) acetamido]-3-[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-l, 2, 4-triazin-3-yl) thiomethyl]-3-cephem-4-carboxylic acid derivatives (2a-2d) were synthesized. Antibacterial activities of these new cephalosporin derivatives and the relationship between their structures and their avtivities were examined. Among them, 7-[(3,4-dihydro-6-methoxycarbonyl-2, 2-dimethyl-2H-l, 4-thiazin-3-yl) -acetamido] -3- [ (2, 5-dihydro-6-hydroxy-2-methyl-5-oxo-l, 2,4-triazin-3-yl) thiomethyl] -3-cep-hem-4-carboxylic acid exhibited the broad antibacterial activities against Gram(+) and Gram (-) bacteria.

상심실성 빈맥환자에서 관상정맥동의 형태비교

현대우,김윤년,박소영,한성욱,허승호,김기식,김권배 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.4

재원기간중 사망한 급성 심근경색증 환자의 임상적 특징

현대우,김기식,신이철,박소영,배장호,한창엽,김윤년,김권배 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.9

Preparation and properties of new polyurethane gels with a stress-distributing function for medical applications

Cha, Gook Chan,Lee, Sukmin,Song, Jeom Sik,Kim, Jong Kwon,Kim, Kyung Hoon,Mun, Mu Seong,Youn, Hyoung Soon,Pyun, Do Gi,Choi, Yoon So Wiley Subscription Services, Inc., A Wiley Company 2006 Journal of applied polymer science Vol.100 No.4

<P>The purpose of this study is to prepare new polyurethane gels that can be used as stress- or pressure-distributing materials, particularly by being combined with selective plasticizers for medical or clinical applications. Because low-molecular-weight plasticizer molecules in polymer gels intrinsically tend to migrate to the surface of the gels by the so-called entropy effect in polymer miscibility, the stress-distributing function may decrease gradually after a certain amount of time. Correspondingly, both the chemical nature of the plasticizer and polymer gels and the compatibility between the polymer segments and plasticizer should be deliberately considered as important factors in determining the thermophysical properties and stress-distributing performance of polymer gels. New polyurethane gels comprising separated phases of soft and hard segments, the glass-transition temperature of which was around the ambient temperature, were prepared, and selective plasticizers were combined to obtain an optimized formulation of gels for stress-relieving properties. The glassy-to-rubbery transition of semicrystalline hard segments occurring around the ambient temperature caused the rearrangement of chain conformations, leading to the reduction of the pressure applied to the surface; this indicated that the pressure buildup or loss was somewhat related to the heat regulation by thermal absorption and release in the phase-transition range. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 2750–2758, 2006</P>

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

Effect of Zinc Addition in Filler Metal on Sacrificial Anode Cathodic Protection of Fin-Tube Aluminum Heat Exchanger

Yoon-Sik So,Eun-Ha Park,Jung-Gu Kim The Korean Electrochemical Society 2023 Journal of electrochemical science and technology Vol.14 No.4

This study investigated the tri-metallic galvanic coupling of different metals in the tubes, fillers, and fins of a heat exchanger. The goal was to prevent corrosion of the tubes using the fin as a sacrificial anode while ensuring that the filler metal has a more noble potential than the fin, to avoid detachment. The metals were arranged in descending order of corrosion potential, with the noblest potential assigned to the tube, followed by the filler metal and the fin. To address a reduction in protection current of the fin, the filler metal was modified by adding Zn to decrease its corrosion potential. However, increasing the Zn content of filler metal also increases its corrosion current. The study examined three different filler metals, considering their corrosion potential, and kinetics. The results suggest that a filler metal with 1.5 wt.% Zn addition is optimal for providing cathodic protection to the tube while reducing the reaction rate of the sacrificial anode.

반응표면분석을 활용한 토양 부식 인자의 열수송관 부식 영향 평가

소윤식(Yoon-Sik So),김정구(Jung-Gu Kim),김우철(Woo-Cheol Kim) 한국에너지기후변화학회 2022 한국에너지기후변화학회 학술대회 Vol.2022 No.10

Outcome of Surgical Treatment in terms of Metastasis in Patients with Stage IV Colorectal Cancer

Yong Sik Yoon,Chan Wook Kim,In Ja Park,Seok-Byung Lim,Chang Sik Yu,So Yeon Kim,Tae Won Kim,Jin Cheon Kim 대한종양외과학회 2014 대한임상종양학회 학술대회지 Vol.2014 No.3

회귀분석을 통한 DH순환수 환경 부식인자에 따른 두께 감육량 산출식 도출

소윤식(Yoon Sik So),임정민(Jeong Min Lim),김우철(Woo Cheol Kim),김정구(Jung Gu Kim) 대한설비공학회 2022 대한설비공학회 학술발표대회논문집 Vol.2022 No.6

In order to evaluate the thickness loss due to corrosion of the district heating pipeline, it is necessary to evaluate various factors affecting corrosion. However, it is difficult to evaluate the corrosion property in all variables because the corrosion factors are varied. Therefore, in this study, the relationship between corrosion factors (pH, dissolved oxygen and period of use) and thickness loss was evaluated through an efficient experimental design using Box-Benhken method in the response surface methodology. For an acceleration of corrosion, a galvanostatic test was used. After that, based on the measured thickness loss, multiple-regression analysis was performed to derive the thickness loss equation according to the corrosion factors. Through this equation, it is expected that the long-term corroison of the metal structures can be predicted simply by measuring the corrosion factors present in the environment.