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Peroxiredoxin V Regulates Aco2, Acadm, and Acox1 Activity in Hypoxic Kidney
Tae‐Hoon Lee,Hee‐Young Yang,Joseph Kwon,Hoon‐In Choi,Lina Ren,Ung Yang,Byung‐Ju Park,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1
Peroxiredoxin V, an atypical thioredoxin peroxidase, is widely expressed in mammalian tissues. In addition, Prdx V is localized in mitochondria, peroxisome, cytosol, and nucleus. Prdx V has been reported to protect a wide range of cellular environments as antioxidant enzyme, and its dysfunctions may be implicated in several diseases, such as cancer, inflammation, and neurodegenerative disease. Identification and relative quantification of proteins affected by Prdx V may help identify novel signaling mechanisms that are important for oxidative stress response. However, the role of Prdx V in the modulation of hypoxia‐related cellular response is not studied yet. In order to examine the function of endogenous Prdx V in hypoxic condition in vivo, we generated a transgenic mouse model with Prdx V siRNA expression controlled by U6 promoter. Of many tissues, the knockdown of Prdx V expression was displayed in kidney, lung, and liver, but not spleen and skin. We conducted on the basis of nano‐UPLC‐MSE proteomic study to identify the Prdx V‐affected protein networks in hypoxic kidneys. In this study, we identified protein networks associated with oxidative stress, fatty acid metabolism, and mitochondrial dysfunction. Our results indicated that Prdx V affected to regulation of kidney homeostasis under hypoxia stress.
Kwon,Ki-Tae,Lee,Woo-Sik,Kwon,Lee-Seung,Seong,Seung-Hwan,Kim,Young-Do,Kwon,Woo-Taeg 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-
It is possible not only to treat high concentration organic matter such as food wastes but also to utilize food wastes as resources according to the bio-energy generation such as methane. The method of co-digestion of mixed wastewater mixed with organic wastes such as sewage sludge concentrated waters together with drinking wastewater is the most ideal method. Radiation not only has germicidal power in water treatment, but also is effective in decomposing degradable organic matter. Second chemical contamination problem is also solved because it does not use chemicals. Introduction of radiation pretreatment system to solve problems caused by mixing of waste water and organic waste resources. Biological electrochemical fusion system is used to remove the nutrients contained in the organic matter-removed mixture. Through the development of a system for treatment of high concentration wastewater, the processing efficiency is verified through the universal water treatment system for wastewater containing high concentration organic matter in addition to treatment of wastewater.
Developpe devant 수행시 하지 관절 모멘트 분석
박기자,신성휴,권문석,김태완,이형나 한국운동역학회 2004 한국운동역학회지 Vol.14 No.1
K. J. PARK, S. H. SHIN, M. S. KWON, T. H. KIM, H. N. LEE. Analysis on lower extremity joint moment during a developpe devant. Korean Journal of Sport Biomechanics, Vol. 14, No. 1, pp. 133-144, 2004. The purpose of this study was to analyze the joint moment on lower extremity during a developpe devant. Data were collected by Kwon3D, KwonGRF program. Two professional modem female dancers were participated in this experiment. Subjects performed a developpe devant in meddle heights. On the axes of X, Y, Z, it was shown that the maximum joint moment was occurred in hip joint. The moments are plotted during developpe devant. The ankle muscles generate a plantar flexion moment and the knee muscles generate a flexion moment and The hip muscles generate a extension moment. So these muscles of joint muscles were known to play a key role in keeping the body balance while doing developpe devant. In addition adduction moment occurred at hip, knee, an ankle in the order of amount, we could assume from this data that turn out motion started from the hip joint. There was small active turn out possible below the hip joint. A small amount of extra turn out could be obtained when standing because of flexion between the foot and floor, which could be used to give a passive external rotation force to the whole leg and this could produce a rotation between the knee and foot. This passive external rotation could produce very damaging results. Therefore, lower extremity joint muscles such as hip, knee, and ankle muscle should be trained to keep the body balance and prevent injury during developpe devant performance. And for the safe and perfect turn ort performance, hip joint abduction, the most important external rotating muscle for turn out is needed to train and full stretching should be done in advance.
사업장(事業場) 근로자(勤勞者)의 사상체질(四象體質)에 따른 생활습관(生活習慣), 자각증상(自覺症狀), 건강인식(健康認識)에 관(關)한 연구(硏究)
서명효,강홍구,장두섭,왕명자,차남현,김삼태,권소희,정해경,송용선,이기남,Seo Muoung-Hoy,Kang Hong-Goo,Jahng Doo-Sub,Wang Myoung-Ja,Cha Nam-Hyun,Kim Sam-Tae,Kwon So-Hee,Jung Hae-Kyoung,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2003 대한예방한의학회지 Vol.7 No.2
The study was conducted to evaluate the difference of life style, subjective symptoms and health cognition depending on the Sasang Constitution in the industrial workers. The results were as follows ; Constitutional distribution among exposed group were Tae-eum In(38.4%), So-eum In(35.2%), and So-yang In(26.4%) and it was turned out that Tae-eum In took a higher portion of Sasang constitution than other constitutions in technician workers. 'Exercise' and 'Obesity' were found most in Tae-eum In, In So-eum In there were many 'Normal' weight and 'Having digestive disorders' were found most in So-eum In. There were no significant difference in the health cognition among the constitutions. The closer to 'normal' weight, the higher prevalence in 'having' concern about health condition and the more 'normal' condition in sleeping, the higher prevalence of 'having' self-confident in present health.
이상한,권대근,백상흠 경북대학교 병원 2002 경북대학교병원의학연구소논문집 Vol.6 No.1
This study was preformed to investigate the average anthropometric value of normal Korean men and women and to compare the preceding literatures.Additionally,average Korean profilogram was made to serve as a template for diagnosis of facial form. Eighty five Korean subjects(41 men 44 women)aged between 21 to 26 were selected by members of the author's department on the basis of intact dentition and ClassⅠocclusion without facial asymmetry.Frontal and lateral photographs were taken under standardized conition with digital camera.The image was magnified and according to the FH plane of cephalometric radiograps and digitized using personal compture. To compare the Western beauty,25 estherically pleasing famale was selected to measure various angle distance of the face. 1. It was possible to calculate the mean coordinate value of Korean normal samples which enables the direct visualization and comparsion with the use of template. The method in this study was easy to applicate under the Microsoft Windows bases. 2. Maxillary vertical hypoplasia, upper and lower lip protrusion was characteristics of Korean norms and relatively narrow alar base distance,less conspicuous nasal projection was observed.As the vermilion exposure and upper lip length was more than western norm,chin looks shorter than western. To compare the Korean and Weastern estherically pleasing profile,facial convexity and nose was less conpicuous in Korean womem.
복압성요실금(Stress urinary incontinence)과 절박성요실금(Urge incontinence)환자에서 TVT 수술 결과의 비교
이경구,이준호,권용욱,정태융,심희영,이상익 관동대학교 의과대학 의과학연구소 2005 關東醫大學術誌 Vol.9 No.1
Tension-free vaginal tape(TVT) has been widely used in the management of stress urinary incontinence(SUI), and has been applied to urge incontinence (UI). We evaluated and compared the outcomes between SUI and UI for patients who had undergone TVT. Patients were categorized into SUI(33 patients) and UI(26 patients). Before treatment, we asked about LUTSs using female bladder questionnaire. And we asked about sexual function. After treatment, the same questionnaires were repeated. During the postperative period, the objective and subjective success rate were evaluated. For operation outcome results, in SUI group there were 29 cases of cure (87.9%)and 2 of improvement(6.1%), and in UI group there were 20 cases of cure(76.9%)and 3 of improvement(11.5%) (p>0.05). The operation satisfaction rate of patients was 90.9% in SUI group and 84.6% in UI group(p>0.05). Improvement of sexual satisfaction occurred in 6(20.0%) of SUI group, and 3 (18.8%) of UI group, respectively(p>0.05). The objective success rate, satisfaction rate and sexual satisfaction of SUI patients did not significantly differ from the women with UI. Also, these results shows that TVT procedure improves some LUTSs in both groups. We consider the TVT procedure to be an effective treatment not for stress urinary incontinence but also urge incontinenece.
신규개발된 제초제 metamifop 현탁농축액제에 대한 급성독성평가
이동연,이상훈,백경진,김태원,정두순,임종환,김명석,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-
Metamifop, (R)-2-[4-[(6-chloro-2-benzoxazolyloxyphenoxy]-N-(2-fluorophenyl)-N-methyl propanamide, was newly developed by Dongbu Hannong Chemicals in Korea. In the present study we conducted acute oral toxicity and acute dermal toxicity test. The values of LD_(50) of metamifop was found to be over 5,000 mg/kg for ICR mice. On the other hand, metamifop showed no acute dermal toxicity to SD rats.