氣功與防止衰老的作用

전신옥,이경섭,남상수,Quan, Xin-Yu,Lee, Kyung-Sub,Nam, Sang-Su 대한예방한의학회 2004 대한예방한의학회지 Vol.8 No.1

The average life span is expanded due to the development of modem society, material and cultural life and increasing level of public health. This means that the aging society is rapidly progressing. Geniatric diseases also have increased due to increasing of the aged population. Along with an increase of the aged patient, the anti-aging, prevention of geniatric disease and quality of life is tending high on social concern and medical issues. Many reports showed the evidence to the positive anti-aging effect of Oriental medicine. Qigong therapy, a kind of Oriental medicine, has been used to prevent aging and life prolongation with positive effect for many thousand years. Therefore, qigong practice is popular and common to middle age and old age in China.

일부 동물성 한약재의 독성과 안전성등급화 - 봉독, 사독, 반묘와 오공을 중심으로 -

박영철,이선동,Park, Yeongchul,Lee, Sundong 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : About 13% of the medicines used by traditional korean medicines(TKM), are called animal medicines and are derived from non-herbal sources such as animals and insects. However, the clinical use of these preparations from animal medicines is often based on tradition and belief, rather than on evidence of toxicity and efficacy. As a result, animal medicines containing toxin have caused serious problems from injecting patients with venom. Here, various venoms frequently used as TKM were reviewed in terms of their instinct toxity and tried to estimate their safety classification. Methods : The estimation of safety classification was based on human equivalent dose(HED)-based MOS (margin of safety) and clinical dose applied for patients. Results and Conclusions : Except that of snake venom due to no clinical dose, they were evaluated as class 3 for bee venom, class 4 for cantharidin, toxin from blister beetle, and class 1 for venom from scolopendrid. In conclusion, animal medicines showed a wide range of safety classification from class 1 to class 4. This wide range is estimated to result from extremely limited applications of each venom for patients because of their strong toxicity. However, it should be cautious for application in clinics since animal medicines can produce anaphylactic reactions particularly after veinous administration even with a tiny amount of venom.

본초 제조 공정의 DB화를 위한 형태소 분석 연구 - 숙지황 제조 공정을 중심으로 -

김태열,김기욱,김병철,이병욱,Kim, Thaeyul,Kim, Kiwook,Kim, Byungchul,Lee, Byungwook 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : Treatment method using drugs has already been used in Korean medicine for a long time. Moreover, database has been developed and utilized for more efficient management of the treatments that use drugs. Most of such database related to knowledge on drugs is composed of origin, efficacy, temperament, ingredients and examples of application of the standardized drugs. Communication with knowledge information in other specialized areas is also accomplished by using the efficacies and ingredients with the drugs. In this study, we aimed to make data structure of the terminologies that represent the manufacturing process of herbs. However, in spite of the fact that the manufacturing process of the drugs imparts effect on their efficacies and ingredients, details of the manufacturing processes are quite limited to simple text sentences, thereby resulting in substantially lower level of utilization and difficulties in systematic researches on various factors included in the manufacturing processes in comparison to other knowledge on drugs. Methods : This Study extracted the factors necessary in the development of database by executing morphological analysis of the manufacturing process of herbs. Results : The factors are 'Order', 'Act', 'Raw material', 'Tools', 'Supporting materials', 'Intensity', 'Duration Time', 'Interval', 'Focus', 'Repetition Number', 'Untill'. We were able to tell the difference of the manufacturing process with a simple structured query language and the factors. Conclusions : Morphological analysis of medicinal herbs manufacturing Process contributes to standardization with information of the manufacturing process. And it helps to creates a quality management system through the Database.

시스템생물학의 한의학적 응용

박영철,이선동,Park, Yeongchul,Lee, Sundong 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

In Korea and China, traditional medicine's holistic approaches, based on the views of whole-body and whole-person, have been applied to make the solution of health problem. However, these holistic approaches of traditional korea or chinese medicine have been limited in interpreting their theories in a view of modern scientific aspects of medicine. This limitation seems to be mainly due to the reductionism approaches of modern scientific medicine. Traditionally, science has taken a reductionism approach; dissecting biological systems into their constituent parts and studying them in isolation. However, systems biology based on omics technologies is providing a new thought and method for traditional medicine's research and interpretation. Systems biology uses integrity study as the characteristic and bioinformatic technology as the key method for connecting reductionism and holism. Therefore, it has much in common with the theory of traditional medicine. It was reviewed that how systems biology is applied to traditional medicine in Korea and China. Also it was suggested that more future researches on interpretation between traditional medicine and systems biology must be focused on personalized medicine since systems biology will have a major impact on future personalized therapeutic approaches.

Low Dose Effect와 Non Monotonic Dose Responses(NMDRs) 그리고 의학적 의미 - 용량-반응관계의 새로운 패러다임을 중심으로 -

성 안젤라동민,신지연,이승은,박송미,오연지,이선동,Sung, Angela Dongmin,Shin, Jeeyoun,Lee, Seungeun,Park, Songmi,Oh, Yeonji,Lee, Sundong 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : The aim was to investigate the characteristics of low dose effect and non monotonic dose responses(NMDRs) and to predict the influence it might have on the health and medicine, traditional Korean medicine. Methods : By investigating recently published major literatures related to low dose effect and NMDRs, the definition, mechanism, major related fields, and the influence on public health and medicine has been categorized and summarized. Results : Although there are still heated debates about the definition of low dose, it implies the biological responses in environmental exposure level and the NDMDRs means the nonlinear relationship between the dose-response in the slope sign change. Also, it implies the new form of the curve showing a U, reverse U shape, and the slop sign constantly changing showing various forms. This mechanism is because the two acceptor shows opposing effects to toxic materials and the affinity is different along with the numerical value that increase and decrease being different. These characteristics generally appear in endocrine disrupters such as bisphenol A, agricultural pesticides, metal, and radiation. The research field in the public health and medical treatment is obesity, problems in metabolism, growth hormone treatment, climacteric treatment, breast cancer, intake of Korean traditional medicine for pregnancy, menopause and phytoestrogen. Conclusions : As a result of discussing implications, NMDRs is a particular effect in low dose and heated debates surround this response, research is being conducted surrounding the field of obesity, problems in metabolism, growth hormone treatment, climacteric treatment, breast cancer, intake of Korean traditional medicine for pregnancy, menopause, and phytoestrogen. More research and interest in needed as it can have a massive influence in the public health and medicine.

뇌성마비 아동의 한방치료 이용실태와 중단원인 연구

박병욱,박요한,유선애,허영진,김성철,윤영주,Park, Byungwook,Park, Yohan,Yu, Sunae,Hur, Youngjin,Kim, Sungchul,Yun, Youngju 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : The purpose of this study was to investigate the real status of the utilization of Korean medicine (KM) treatment among children with cerebral palsy (CP). Methods : In a prospective observational multicenter study for children with CP aged from 6 months to 78 months, we analyzed 69 questionnaires of children currently receiving or have received KM treatment such as acupuncture and Korean herbal medicine for CP. Results : Of all the 170 participants, 32 children was currently getting KM treatment and they were getting acupuncture therapy 2.5 times per week on average. The mean expenditure per month for acupuncture and herbal medicine was respectively 32,000won and 501,000won. 37 children have discontinued KM treatment. The most frequent reason for quitting acupuncture therapy was 'inconvenience' (40.7%), followed by 'suffering of children' (33.3%). The average duration of taking Korean herbal medicine was 3.78 months and the highest reason of stopping medicine was 'rejection of children' (32.3%), followed by the 'cost burden' (22.6%). 75% of currently KM using group answered they have experienced positive effect of KM and the rate was 48.6% among the group who have ceased KM. There was a significant difference between the two groups(p=0.025). Conclusions : Further study will be required to increase the therapeutic effect and utilization of KM among the children with CP. More efforts should be made to develop less invasive acupuncture method and various shape of KM herbal medicine and to expand the insurance coverage of KM for children with CP.

국내외 코호트 사업 고찰 및 한의학 코호트 구축

김지영,백영화,이시우,고광필,유종향,Kim, Jiyoung,Baek, Younghwa,Lee, Siwoo,Ko, Kwang Pil,Yoo, Jonghyang 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : In this study, we investigated the trends of cohort project in domestic and overseas, and suggested the necessity of cohort on korean medicine and the direction of research. Methods : The papers which include cohort in the title and published by 2015 were searched using PubMed. In order to study the history of cohort in domestic and overseas, research trend was investigated based on the websites of each cohort projects and traditional medicine searching engine named OASIS. Results : Using PubMed, 42,802 papers were searched. Most of the studies over 50 % of total articles, however, were conducted in these 6 years. Nevertheless, cohort studies are being actively proceed, the korean medicine based on cohort studies are nonexistent. Therefore, further discussion about cohort study on korean medicine is necessary to gather physiological index and clinical index of korean medicine consistently. Conclusions : Systematically constructed cohort on korean medicine would be the foundation which collects information, such as gene information, bio information, dietary habit, life style, and Pattern identification (辨證), and integrates them. The analysis of massive clinical materials could suggest the basis of Prevention and treatment of korean medicine considering the difference between personal.

근거 중심 Kampo medicine 임상진료지침의 현황

사사키 유이,황정운,김경한,박유리,심호종,박동선,전윤정,김지환,장보형,신용철,고성규,Sasaki, Yui,Huang, Ching Wen,Kim, Kyeong Han,Park, Yu Lee,Shim, Ho Jong,Park, Dong Sun,Jeon, Yoon Jeong,Kim, Ji-Hwan,Jang, Bo-Hyoung,Shin, Yong-Cheol,Ko, 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : In 2007, a survey of how Kampo was regarded in Japanese clinical practice guidelines (CPGs) was first conducted by the Special Committee for Evidence Based Medicine (EBM), namely the Japan Society for Oriental Medicine (JSOM). A manual for CPG development was also published in 2007 by the Japan Council for Quality Health Care, and the revised edition came out in 2014. The purpose this study is to review the current state in CPGs applied to Kampo after 2007, while focusing on how Kampo products being regarded evidence based branch of medicine by CPG developers. Methods : Sources include the Kampo CPGs website of Japan Society for Oriental Medicine (JSOM) and MINDS (Medical Information Network Distribution Service) website of Japan Council for Quality Health Care. Results : Among the 784 CPGs existing by the end of 2015, 91 CPGs were considered containing descriptions of Kampo. Furthermore, 28 type A Kampo CPG (KCPG) which had quality of evidence and strength of recommendation with references were found. Also, most of type A KCPGs relied on the MINDS Handbook for Clinical Practice Guideline Development that was published in 2007. Conclusions : The number of KCPGs are increasing yearly. However, there is still not much Kampo evidence found in CPGs in Japan. Overall, it could be said that we need to not only make evidence vertically but preach it horizontally well.

한의대생의 글쓰기가 자존감에 미치는 영향

문준석,신헌태,Moon, JoonSeok,Shin, HeonTae 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : Self-esteem is a necessary inner factor for the korean medicine undergraduate, who will perform a various treatment relationship as a future health care provider. Writing is closely related with improving self-esteem by providing insight towards oneself. Methods : The level of self-esteem and current state of writing among 251 undergraduates studying korean medicine in Dongshin University were looked into through a structural survey. Results : Self-esteem score was 3.12 on a scale of 4 which was relatively high, but they showed defensive self-esteem tendency. Meanwhile writing variables appeared to be more influential to the self-esteem of undergraduates than personal characteristics. Also among writing variables, emotional writing and writing 2 to 3 times or more a month was related to high self-esteem which defensive self-esteem tendency is low. Majority of the undergraduates, however, turned out to be writing essay and writing 2 to 3 times a month. Conclusions : The following result suggests the need of writing classes as well as writing involved in emotion for self-esteem and improve medical communication in the curriculum of korean medical college.

근골격계 질환에 대한 경근무늬측정검사(모아레)의 한의약적 임상응용 고찰

류홍선,송애진,정명수,Ryu, Hongsun,Song, Aejin,Chong, Myongsoo 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : This study aims to classify and analyze literature related to moire topography, as a diagnostic device of Korean medicine, discuss research trends and major results, and demonstrate the value of moire topography. Methods : To investigate moire topography research trends, Korean keywords that signify 'moire' were searched in a Korean journal search engine. Initially, 2,988 papers were found in the research, and, after classifying them and removing those that are duplicate in other databases, only 37 papers were applicable for the literature review in this study. To analyze research trends, the 37 papers were analyzed based on the publication year, research field, journal, and research type, and, clinical articles were classified based on the diagnosis purpose, subject characteristics, diagnosis method, test method, and test result, for analysis. Results : Moire topography research in South Korea was first conducted in 1995 and most active in 2003, mostly in the field of Korean medicine. In the journal analysis, The Journal of Korea CHUNA Manual Medicine for Spine & Nerves published the highest number of papers, most of which were clinical articles and the rest were literature review. And, in the analysis of clinical papers, based on the diagnosis purpose, muscle somatotype measurement was most common, followed by diagnosis of scoliosis. In terms of subjects, most studies focused on elementary, middle, and high school students, and, in terms of the diagnosis method, other tests were used in most studies. The analysis of moire topography methods showed that most studies measured the shoulder, back, and hip, and the most common measurement method in the studies measured the difference in contour lines on the left and right by designating a central line of the body. In terms of the result, most moire topography brought about significant diagnosis results, and many studies demonstrated its use for musculoskeletal diseases in particular. Conclusions : Moire topography is believed to be highly significant for diagnosis and treatment of musculoskeletal diseases and further research will be needed to support it.