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      • KCI등재

        실용음악 전공 학생들의 발성치료 전후 성대 및 음성 특성 비교

        황연신,심미란,김철준,최용석,김상연,최찬호,선동일,Hwang, Yeon Shin,Shim, Mi Ran,Kim, Chul Jun,Choi, Yong Suk,Kim, Sang Yeon,Choi, Chan Ho,Sun, Dong Il 대한후두음성언어의학회 2016 대한후두음성언어의학회지 Vol.27 No.2

        Background and Objectives : Many students major in applied music singing have various difficulties in phonation when they sing or perform. But the studies about this cause are lack. The purpose of this study is whether singing voice therapy based on vocal music is effective or not to applied music singing students that have difficulties in phonation. Materials and Methods : Singing voice therapy program had been done to 8 students major in applied music singing during 7 weeks. We did laryngeal stroboscope, perceptual, acoustic and aerodynamic examination before and after singing voice therapy to this students. And we studied post examination results have differences or improvements compared to pre examination results. Results : Four male students don't have effective improvement after singing voice therapy but they shows slight improvement in aerodynamic examination values compared to pre examination values. Four female students shows improvement in aerodynamic examination values and pitch range increasing. Above all, one student's vocal nodules disappeared after singing voice therapy. Conclusion : Singing voice therapy based on music singing is very effective to the students major in applied music singing. Above all, their curriculum in applied music singing should include phonation training based on music singing before training perform and technic practices.

      • 中樞性 交感神經 效能藥의 體溫調節에 미치는 影響

        신인철,서대규,이승도 漢陽大學校 環境科學硏究所 1989 環境科學論文集 Vol.10 No.-

        生體機能의 均衡을 維持하는데는 體溫調節이 重要한 役割을 하며 體溫은 體內의 體溫調節機構의 作用으로 體熱의 生産과 發散間의 均衡을 이루어 一定한 節圍로 保存되고 있다. 中樞性 體溫調節에는 brain monoamines의 濃度가 重要한 役割을 하며 中樞性 交感神經效能藥인 methamphetamine은 brain monoamines 溫度를 上昇케 하고 methyldopa는 이를 下降케 한다고 알려져있고 ethanol은 noradrenaline 또는 5-hydroxytryptamine을 通하여 體溫下降을 招來케 한다고 알려져 있으므로 ethanol誘發 低體溫症에 對한 methamphetamine 및 methyldopa의 作用을 생쥐에서 實驗的으로 比較檢討하여 다음과 같은 結果를 얻을 수 있었다. Ethanol(3g/kg)의 腹腔內住射는 顯著한 體溫下降(低體溫症)을 招來하였으며 이 作用은 注射後 60分頃부터 發現되어 實驗終了時까지 持續되었다. Methamphetamine(1,2 및 4mg/kg. 腹腔內注射)은 用量에 比例하여 體溫을 上昇케 하였으나 methyldopa(1,2 및 4mg/kg. 腹腔內注射)는 對照的으로 體溫을 下降케 하였고 이 作用은 用量增加에 따라 減弱되었다. Ethanol 低體溫症에 對해서는 methamphetamine을 抗拮的으로 作用하였으나 methyldopa(1 및 2mg/kg)는 이에 影響을 미치지 않았고 比較的 大量(4mg/kg)은 ethanol 低體溫症에 拮抗的으로 作用하였다. Ethanol 前處置는 methamphetamine에 依한 體溫上昇作用을 抑制하였고 比較的 大量(4mg/kg)의 methyldopa에 依한 體溫下降作用을 增强하였다. Brain monoamines among other brain neurotransmitters play a role in thermoregulation. Methamphetamine causes increased brain monoamine levels, while the converse is true for methyldopa. The effects of drugs that may influence braine monoamines, d-methylamphetamine(1,2, and 4mg/kg, i.p.) and α-methyldopa(1,2, and 4mg/kg, i.p.) on rectal temperature and on ethanol(3g/kg, i.p.) induced hypothermia have been investigated in mice. Ethanol causes a significant reduction in rectal temperature which lasted from the time interval starting at 60min to end of the experiment. Methamphetaminecaused a significant hyperthermia in a dose-dependent manner, but methyldopa induced hypothermia, which decreased with increases in dose. Methamphetamine antagonized the hypothermic effect of ethanol but methyldopa did not affect it. Methyldopa in high doses(4mg/kg), however, reversed ethanol-induced hypothermia. Ethanol pretreatment significantly potentiated the hypothermic effet of methyldopa(4mg/kg) and it prevented methamphetamine-induced hyperthermia.

      • 요부수핵탈출증에서 Thermography의 진단적 가치

        신현택,신승우,송재철,정석희,이종수,김성수,신현대 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

        Objectives : Lumbar radiculopathy is a common disease in oriental rehabilitation medicine. It can be diagnosed by physical examination, plain X-ray, Myelography, CT, MRI, EMG etc. But those methods are not useful in observing the clinical procedure. Objectvie evaluating the clinical procedure is very important in treatment of lumbar radiculopathy. Mehthods : We studied the clinical efficacy of thermography in lumbar radiculopathy during conservative managements. We studied 36 patients with lumbar radiculopathy convinced by MRI. The had low back pain and radiating pain on one side. Thermography had taken before an after 4 weeks treatments, and compared with clinical procedure Results and conclusions : Thermography is not pertinent as a primary diagnostic method in lumbar radiculopathy, but useful in observing the clinical procedure. And it can be recommended as a objective evaluation for lumbar radiculopathy.

      • KCI등재후보

        급성 림프구성 백혈병 환자에서 발생한 침습성 국균 심내막염 2예

        신성철,백경란,정재홍,송봉근,김동희,전경만,채제욱,손준성,정숙인,오원섭,송재훈 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

        국균은 호흡기를 통해 유입되며 심한 면역기능저하 환자에서 기회감염을 일으키는 진균이며 주로 혈관을 따라 폐를 침범하고 심장과 골침범은 매우 드문 것으로 알려져 있다. 저자들은 급성 림프구성 백혈병 환자에서 발생한 침습성 국균 심내막염을 2예을 경험하였다. 19세 남자환자로 동종 조혈모세포이식 후 발생한 고열과 요통의 원인으로 감염성 심내막염 진단하에 수술결과 국균에 의한 감염으로 확증되어 수술적 절제술과 liposomal amphotericin B로 치료하였으나 국균 심내막염의 재발과 국균 척추염의 악화, 뇌 출혈로 사망하였다. 23세 남자환자로 관해요법 후 발생한 고열과 요통의 원인으로 국균 심내막염과 국균 척추염 진단하에 수술적 절제술과 amphotericin B로 치료하여 1년 2개월 동안 국균 심내막염의 재발은 없었으나 지속적인 백혈병의 재발과 국균 척추염의 악화, 침습성 폐 국균증으로 사망하였다. Although Aspergillus endocarditis has rarely been reported, it can cause fatal complications in hematologic malignancy patients and allogeneic stem cell transplant recipients. We experienced two cases of aspergillus endocarditis developed in acute lymphoblastic leukemia patients. Case; A 19-year-old patient developed Aspergillus endocarditis after allogenic hemopoietic stem cell transplantation. He was treated with surgical intervention and liposomal amphotericin B. He died of recurred Aspergillus endocarditis and cerebral hemorrhage probably related with aspergillosis of central nervous system. Case 2; A 23-year-old patient developed invasive Aspergillus endocarditis after induction chemotherapy. Aspergillus endocarditis was successfully treated by surgical intervention and amphotericin B. He died of refractory neutropenic fever and sepsis after the third relapse of leukemia and repetitive chemotherapy. He probably had invasive pulmonary aspergillosis without evidence of endocarditis recurrence. Because the mortality of Aspergillus endocarditis is very high, early diagnosis and surgical intervention are very important for better outcome.

      • 李 箱 文 學 論 : 作品에 投影된 精神分析學的 要因을 中心으로 Psychoanalytical elements projected in his works

        申尙澈 東亞大學校 國語國文學科 1978 국어국문학 Vol.2 No.-

        In the paper, the writer surveyed the psychoanalytical aspect of I-Sang's works that has sur-realism, neo-psychological character based on many materials and researches by pathological method related to consciousness. The aspects projected in his poetries are as follows : First, the position of 'I' in his poetry and 'I'(ego) at the disruption of self in over-self consciousness is on the mirror. The atmosphere swirling in the poetry is dark and unrest. I-Sang's esprit is in the emancipation of 'Be in prison' with dismal faces and 'another different myself'. Second, the outstanding phase in I-Sang's poetry, sexual amusement is expressed in terrific style for instance, the sword of 'submersion', the farrel of 'muzzel of the gun' and the chocolate of 'the confession of unreasonable woman' and 'angels of performance' are the metaphorical penis. Third, the other feature found in his poetry is impetus for suicide. Though 'the canvass of suicide' is shown in his 'poetry' No 15' and 'subject that has no title', he provides suicide to the extent of 'I insert autographical obituary in my autobiobraphy on the day' in his poetry '1933. 6 . 1' The aspects which has psychoanalytical elements in his prose are as follows : Firstly, the point is that he deals with the thing beyond common sense and unconscious world rather than his literary world, daily lives, or conscious world. By examining the expression of his 'when the finger is taken prisoner of self-consciousness' or 'the secret of the last moment stretching oneself on the summit of self-corsciousness' in his first person fiction, 'all his life' , we realize that his fictions are based on his experiences, and depict the world of self-consciousness. Secondly, the heroes in his fictions, for the most part, are autism patients with their backs towards reality squeezed into themselves. The pulling over coverlet in the dark room without any outside negotiation is 'my' life in 'wings' and 'genius turned into stuffing'. All characters in the 'I' of 'Tonghae', 'he' of 'spiders' and 'I' in his essay 'Languor' are the same types. Thirdly, the other aspect searched out in his fictions is that sexual amusements are placed all over the works as in poems. The putting memorial stamp on the fiction 'bobbed hair' that means his importent erotic mind is the metaphor of sexual intercourse. This sexual amusement is expressed more metaphorically in 'spiders'. Fourth, another aspect in I-Sang's fiction in impulse of suicide as in his poetry. The last subdivision of 'TongHae' menas the thinking of suicide looking at the comedy(the man replacing his shose with another) the impulse of suicide like this is traced in 'Lost Flowers' 'Illusions' and his essay, 'The rest emotion of a village).

      • R.C. Slab System의 信賴性解析 및 設計規準

        申鉉默,李相哲 成均館大學校 科學技術硏究所 1983 論文集 Vol.34 No.2

        This study proposes a reliability based design criteria for the reinforced concrete slab system. Resistence and load factors corresponding to the target reliability index (β_0 = = 3.0) which is considered to be appropriate level of reliability are calculated by using the proposed methods. Because of the large variation in load-effect uncertainties, the magnitudes of the factors varied considerably depending on the design section being considered. The same set of load factors associated with different resistence factors for each different design bay of a slab system are adopted as a reliability based design criteria for the purpose of practical. design applications.

      • SCOPUSSCIEKCI등재

        뇌수막종에 관한 연구 : 병리조직학적, 면역조직화학적 및 중합효소연쇄반응을 중심으로

        신호,임성철,이선일 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.3

        Meningioma is the most common primary intracranial neoplasm that orginates from the meningothelial cells. It occurs mainly in adults, and has a female preponderance. It is classically into three main types : meningotheliomatous or syncytial type, fibrous or fibroblastic type, and transitional type. Transforming growth factor α(TGF-α) was known as a neoplastic transformer found in the neoplastic tissue of the brain rather than in normal tissue. In the neoplastic tissue, the expression of the TGF-α was more intense in the malignant rather than benign tumor, but, the expression of the TGF-α on the meningioma was not reported. Transforming growth factor-β(TGF-β) was known as a peptide which is involved in the proliferation of the mesenchymal cells and the other many physiologic processes. Tumor necrosis factor(TNF) has a selective necrotic action of the neoplastic cells without influence on normal tissues. Epidermal growth factor(EGF) and epidermal growth factor receptor(EGR) have a control effect on cellular proliferation and differentiation, and the expression of the EGR in breast cancer has a reverse correlation to the expression of the setrogen receptor(ER). The meningioma is the most common host tumor of breast cancer among the intracranial neoplasm, so presence of some estrogen receptors in the meningioma is suspected. The correlation of the estrogen receptor expression to EGR expression in the meningioma is the concern of this study. Therefore, the authors have observed the meningioma on the basis of the expression of the EG, TGF-α, TGFβ, TNF-β, EGF and EGR were more intensely positive in 2 out of 25 examined cases, especially in the vascular wall and perivascular area. TNF-β expression was weakly positive to focal area only in one case of the meningotheliomatous type. The ER expression was weakly positive to focal areas. The subtypes of meningioma expressing positively were meningotheliomatous and transitional type, which were not related to tumor aggressiveness or poor prognosis. In conclusion, ER, EGF-α, TGF-β, TNF-β, EGF and EGR were expressed in the meningioma, and it is suspected that these factors may be involved in the tumorigenesis or "host" tumor action rather than in tumor aggressiveness.

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