상백피에서 추출한 단백질 분해효소의 특성

권순경,박상욱,최우영 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

상백피에서 추출한 단백질 분해효소의 효소적 성질을 분석하였다. 상백피 추출액으로부터 분리한 단백질 함량은 1.12mg/ml, protease는 비활성도로서 5.14U/mg 수준이었다. 효소의 기질에 대한 특이성은 casein을 100으로 하였을 때 albumin 63, collagen 58, hemoglobin 45, gelatin 36의 비율로 가수분해하여 육류 단백질에 주로 함유된 collagen, hemoglobin을 분해하는 능력이 비교적 큰 것으로 나타났다. 효소의 최적온도는 60℃, 열안정성은 50∼80℃로서 비교적 열에 안정하였다. 효소의 최적 pH는 6.0이었으며 pH 6.0∼7.0에서 안정하였고 pH 9.0 이상에서는 활성이 급격히 저하되었다. 따라서 옛날부터 가정에서 고기를 삶을 때 연회를 위하여 사용하였던 상백피 중에 단백질 분해효소력이 존재함을 확인하였다. Water extract of mulberry tree barks(Morus alba Linne) was studied for its proteolytic activity. Protein content of the extract was 1.12 ㎎/ml and its specific activity was 5.14 U/ml. The enzyme was active on various proteins : the relative acitities were 100 for casein, 63 for albumin, 58 for collagen, 45 for hemoglobin and 36 for gelatin, respectively. These suggested that the ability of the enzyme to hydrolyze meat was relatively high since those are major meat proteins. Optimum pH and temperature for proteolytic activity were : pH 6.0 and 60℃. And the enzyme was stable at the pH range of 6.0 to 7.0 and temperature between 50 and 80℃. Apparent proteolytic activities could support some scientific grounds of traditional application of mulberry tree barks to home cooking for meat tenderization.

상백피 첨가에 따른 숙육의 연화와 관능적 특성

박상욱,권순경 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

상백피 첨가에 다른 숙육의 연화와 관능적 특성을 알아보기 위하여 숙육의 전단력, 조리손실, pH, 단백질함량, 관능적 검사 등을 분석하였다. 전단력은 상백피 첨가량이 증가함에 따라 감소하여 숙육의 연화도가 증가하는 것으로 나타났다. 즉 상백피를 첨가하지 않은 군과 비교해 볼 때 2.5%, 상백피 첨가시는 8.8%, 5,0% 첨가시는 25%, 7.5% 첨가시는 47%, 10% 첨가시는 58%로 각각 숙육의 연화도는 증가하였다. 숙육의 조리손실은 상백피를 0, 2.5, 5.0, 7.5, 10% 첨가함에 따라 44.5, 45.3, 45.8, 47.5, 50%로 증가하였다. 숙육의 pH는 상백피의 첨가하는 양이 증가할수록 5.60∼5.46의 범위로 다소 낮아졌다. 숙육의 단백질함량은 상백피를 첨가하는 양이 증가할수록 감소하였고 육수의 단백질함량은 증가하였다. 숙육의 관능검사 결과에서는 전반적으로 상백피를 첨가하지 않은 군보다 상백피를 첨가한 군에서 모두 높은 기호도를 보였으며 시료간에 유의적인 차이를 나타냈다. 특히 연화도에서는 10% 상백피 첨가시 유의적으로 가장 높게 나타났으며 색도, 향미, 다즙성, 전체적인 기호도에서는 5% 상백피 첨가군에서 유의적으로 높게 평가되었다. 따라서 이와 같은 결과를 종합해 볼 때 숙육제조시 상백피를 5% 수준으로 첨가하는 것이 전체적인 기호면에서 바람직하다고 생각한다. Tenderization of beef by the addition of barks(Morus alba Linne) and its sensory properties were observed by shearing test, cooking loss, pH, protein content and sensory evaluation. Shear force was decreased as the addition level of barks(Morus alba Linne) increased. Tenderization effect of beef was increased 8.8% at the addition level of 2.5%, 25% at 5.0%, 47% at 7.5%, 58% at 10% barks(Morus alba Linne). Cooking loss was observed 44.50% at the no addition, 45.3% at 2.5%, 45.8% at 5.0%, 47.5% at 7.5%, 50.0% at 10% addition level of barks(Morus alba Linne). As the addition level of barks(Morus alba Linne) increased pH of cooked beef decreased to the range of 5.6 to 5.46. As the addition level of barks (Morus alba Linne) increased protein content of beef decreased whereas protein content of cooked liquor increased. The addition of barks(Morus alba Linne) improved the sensory quality of cooked beef. Especially, tenderness scored the highest value in 10% added beef and other quality factors color, flavor, juiciness and overall quality were evaluated significantly high in 5% added beef. Therefore 5% addition level of barks(Morus alba Linne) for cooking beef was suggested as the desirable level of addition.

열역학 실험식에 의한 Cd-Zn계의 안정 및 준안정 상태도의 계산

崔舜惇,權海旭,金星秀 嶺南大學校 工業技術硏究所 1986 연구보고 Vol.14 No.2

For quantitative predictions of the metastable features and the compact expression of phase equilibria encountered in the extractive metallurgy of cadmium and zine, the calculations of stable and metastable equilibrium diagrams of the Cd-Zn system are made using the four parameter subregular solution model. Parameters of the thermodynamic functions are derived from the phase diagram data of "Bulletin of Alloy Phase Diagrams" and the enthalpy data of Wittig and Kleppa. Stable equilibrium diagram and thermodynamic quantities re-calculated from the optimized parameters agree with all the experimental data within the errors. Such metastable phase equilibria as the chemical spinodals, the locus of compositions and temperature where the Gibbs energies of the liquid and solid are equal(To), the metastable extensions of the solidus and liquidus curves, and metastable miscibility gaps. Excellent agreement of the calculated solvus boundary data with the experimental data is believed to provide a correct expectation of the metastable phase equilibria.

노면표시 제거 자동화 장비개발을 위한 작업공정분석

한재구,김균태,권순옥,함영복 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

Present removal work for road signs has been required many workers and times because it has been worked by a manually controlled shaving equipment. While these manual works are progressing, there are unwillingly traffic jam by passing control, and unexpected accidents to all workers exposed dangerous road circumstance. Besides, in current shaving method, there are high potentialities on air pollution as well as explosive accidents occurred by using propane gas. However there have been little efforts to improve technical impediments and to develop a new method or equipment related to the road sign erasing works in domestic construction industry. The purpose of this study is to investigate the road sign erasing work processes of the existing in detail and to analyze the required performance criteria for the automated equipment development.

이중언어자에서 보인 두 형태의 실어증 : 증례보고 A Case Report

나해리,이정욱,박성민,박수열,권순용,이현정 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.2

Since many people in Korea know more than one language, bilingual aphasia is an important line of research in clinical and theoretical neurolinguistics. Nowadays we meet many people who speak other languages along with Korean, who are immigrants from foreign countries, especially from China. Differential recovery of language affected by an aphasic deficit is documented. In the present work, we introduced a patient with bilingual aphasia who showed different recovery patterns in Korean and Chinese. A 66-year-old man was presented with language disturbance and right hemiplegia. On past medical history, he had received a hematoma evacuation through burr-hole due to left basal ganglia hemorrhage. After the event, he showed nearly global aphasia in Korean, but he showed minimally preserved language function on comprehension and fluency in Chinese. This result suggests that aphasia in bilingual subject may show different pat-terns of recovery between two languages.

Escherichia coli 패혈증 환자에 합병된 대칭적 하지 말단 괴사증 1예

남해성,유진홍,권순석,민준기,조현선,박민경,심병주,남유정,이지인,김진수,길욱현,조근종,신완식 대한감염학회 2005 감염과 화학요법 Vol.37 No.6

We have encountered a rare case of symmetrical peripheral gangrene complicating Escherichia coli sepsis in a 47-years-old male. He was successfully treated with antibiotics, anticoagulants, and vasodilator. To our knowledge, this is the first report on symmetrical peripheral gangrene complicating E. coli sepsis in Korea.

Epidermal Growth Factor(EGF)가 개의 손상된 슬관절 전방십자인대의 치유에 미치는 영향

김용식,정도현,정진화,우영균,임영욱,이화성,권순용 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

식이섬유 보충 음료의 섭취와 규칙적 운동에 따른 비만관련 체구성 요인 및 혈중 요인의 변화

임용택,김성수,윤성진,강선영,김재등,박인성,권순욱,이충영 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The purpose of this study was to investigate the effect of drink including dietary fiber supplementation and regulatory exercise on body composition and blood profile concerning obesity of women. Twenty young healthy but on mild obesity women were participated as a subject, Body composition and blood profile were measured before and after 6 weeks' supplementation and exercise, The results of this study were as follows: First, Body composition concerning obesity such as body weight(p=.0001) and %body fat(p=.0001) after 6weeks' dietary fiber supplementation and exercise was decreased significantly. Second, blood profile concerning obesity such as TC(p=.0001), LDL-C(p=.0001) and TG(p=.0002.) after 6weeks' dietary fiber supplementation and exercise was decreased significantly. This results suggested that drink including dietary fiber supplementation and regulatory exercise should be recommended as a effective method for cure and prevention obesity.

A case of hypopigmented cellular blue nevus (초)

( Soon Kwon Hong ),( Kyung Jong Cho ),( Jong Keun Seo ),( Deborah Lee ),( Ho Suk Sung ),( Seon Wook Hwang ) 대한피부과학회 2009 초록집 Vol.47 No.10

Real-life experience of ledipasvir and sofosbuvir for HCV infected Korean patients: a multicenter cohort study

Soon Kyu Lee,Sung Won Lee,Hae Lim Lee,Hee Yeon Kim,Chang Wook Kim,Do Seon Song,U Im Chang,Jin Mo Yang,Sun Hong Yoo,Jung Hyun Kwon,Soon Woo Nam,Seok-Hwan Kim,Myeong Jun Song,Jaejun Lee,Hyun Yang,Si Hyu 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.6

Background/Aims : To evaluate the efficacy and safety of ledipasvir/sofosbuvir (LDV/SOF) therapy in hepatitis C virus (HCV)-infected Korean patients in a real clinical setting. Methods: A total of 273 patients who received LDV/SOF therapy between May 2016 and February 2021 were consecutively enrolled and analyzed. A per-protocol analysis was performed to evaluate the virologic response. Results: Seventy-five percent were infected with genotype 1, and 25% were infected with genotype 2. A hundred eightyone (66.3%) patients had chronic hepatitis, 74 (27.1%) had compensated cirrhosis, eight (2.9%) had decompensated cirrhosis, and 10 (3.7%) had undergone liver transplantation. Undetectable HCV RNA at week 4 was achieved in 90.2% (231/256) of patients, 99.2% (250/252) achieved the end of treatment response, and 98.1% (202/206) achieved sustained virologic response at 12 weeks post-treatment (SVR12). According to liver function, the SVR12 rates were 99.3% (135/136) in chronic hepatitis, 96.4% (53/55) in compensated cirrhosis, and 100% (6/6) in decompensated cirrhosis. The SVR12 rates according to the genotype were 98.2% (167/170) for genotype 1 and 97.2% (35/36) for genotype 2. An 8-week LDV/SOF treatment in treatment-naïve chronic hepatitis patients with HCV RNA < 6,000,000 IU/mL at baseline resulted in 100% (23/23) SVR12 rates. Overall, LDV/SOF was tolerated well, with a 0.7% (2/273) discontinuation rate due to adverse events that were unrelated to LDV/SOF. Conclusions: LDV/SOF is effective and safe for treating HCV-infected Korean patients with high SVR12 rates.